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K. Hargadon · SciRah

Researcher profile · Semantic Scholar

K. Hargadon

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K. Hargadon — researcher profile on SciRah

h-index: 14
Works: 52
Citations: 1,651

Most-cited papers

Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors.
K. Hargadon, Coleman E. Johnson, C. J. Williams
2018International Immunopharmacology1,061 citations
Semantic Scholar
Tumor-Altered Dendritic Cell Function: Implications for Anti-Tumor Immunity
K. Hargadon
2013Frontiers in Immunology121 citations Open access
Semantic Scholar
Incomplete Differentiation of Antigen-Specific CD8 T Cells in Tumor-Draining Lymph Nodes1
K. Hargadon, C. Brinkman, Stacey L. Sheasley-O’Neill, L. Nichols +2 more
2006Journal of Immunology67 citations Open access
Semantic Scholar
Tumor microenvironmental influences on dendritic cell and T cell function: A focus on clinically relevant immunologic and metabolic checkpoints
K. Hargadon
2020Clinical and Translational Medicine58 citations Open access
Semantic Scholar
Strategies to Improve the Efficacy of Dendritic Cell-Based Immunotherapy for Melanoma
K. Hargadon
2017Frontiers in Immunology54 citations Open access
Semantic Scholar
Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity
K. Hargadon
2016Journal of Clinical Medicine45 citations Open access
Semantic Scholar
Suppression of the maturation and activation of the dendritic cell line DC2.4 by melanoma-derived factors.
K. Hargadon, Osric A. Forrest, Pranay Reddy
2012Cellular Immunology32 citations
Semantic Scholar
Genetic dysregulation of immunologic and oncogenic signaling pathways associated with tumor-intrinsic immune resistance: a molecular basis for combination targeted therapy-immunotherapy for cancer
K. Hargadon
2023Cellular and Molecular Life Sciences28 citations Open access
Semantic Scholar
Major Histocompatibility Complex Class II Expression and Hemagglutinin Subtype Influence the Infectivity of Type A Influenza Virus for Respiratory Dendritic Cells
K. Hargadon, Hai-Xia Zhou, R. Albrecht, Haley A. Dodd +2 more
2011Journal of Virology26 citations Open access
Semantic Scholar
A model system for the study of gene expression in the undergraduate laboratory
K. Hargadon
2016Biochemistry and Molecular Biology Education18 citations Open access
Semantic Scholar
Oncogenic functions of the FOXC2 transcription factor: a hallmarks of cancer perspective.
K. Hargadon, Travis B. Goodloe, Nathaniel D Lloyd
2022Cancer metastasis reviews17 citations
Semantic Scholar
The FOXC2 Transcription Factor Promotes Melanoma Outgrowth and Regulates Expression of Genes Associated With Drug Resistance and Interferon Responsiveness
K. Hargadon, Balázs Győrffy, Elijah W. Strong, Brian D. Tarnai +4 more
2019Cancer Genomics & Proteomics16 citations Open access
Semantic Scholar
Murine and Human Model Systems for the Study of Dendritic Cell Immunobiology
K. Hargadon
2014International Reviews of Immunology16 citations
Semantic Scholar
The role of interferons in melanoma resistance to immune checkpoint blockade: mechanisms of escape and therapeutic implications
K. Hargadon
2021British Journal of Dermatology14 citations
Semantic Scholar
Melanoma-Associated Suppression of the Dendritic Cell Lines DC2.4 and Jawsii
K. Hargadon, Yonathan T. Ararso, Osric A. Forrest, C. M. Harte
201213 citations Open access
Semantic Scholar
The FOXC2 Transcription Factor: A Master Regulator of Chemoresistance in Cancer
K. Hargadon, Elijah W. Strong
2023Technology in Cancer Research and Treatment11 citations Open access
Semantic Scholar
Detection of Ranavirus in Eastern Fence Lizards and Eastern Box Turtles in Central Virginia
Rachel M. Goodman, K. Hargadon, E. Carter
2018Northeastern Naturalist10 citations
Semantic Scholar
The prognostic significance of FOXC2 gene expression in cancer: A comprehensive analysis of RNA-seq data from the cancer genome atlas.
K. Hargadon, Balázs Győrffy, Elijah W. Strong
2021Cancer Genetics8 citations
Semantic Scholar
Genomic and transcriptional changes in IFNγ pathway genes are putative biomarkers of response to ipilimumab immunotherapy in melanoma patients
K. Hargadon, Balázs Győrffy, T. J. McGee
2020Expert Review of Clinical Immunology7 citations
Semantic Scholar
RNA-seq Analysis of Wild-Type vs. FOXC2-Deficient Melanoma Cells Reveals a Role for the FOXC2 Transcription Factor in the Regulation of Multiple Oncogenic Pathways
K. Hargadon, C. J. Williams
2020Frontiers in Oncology7 citations Open access
Semantic Scholar
Using The Cancer Genome Atlas as a Tool to Improve Undergraduate Student Understanding of Cancer Genetics and the Hallmarks of Cancer Progression
K. Hargadon
2021Journal of Cancer Education3 citations
Semantic Scholar
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity
K. Hargadon
2015Oncoimmunology3 citations Open access
Semantic Scholar
Melanoma Immunotherapy: Overcoming Obstacles to Augment Anti-Tumor Immune Responses
K. Hargadon
20133 citations Open access
Semantic Scholar
Lymph Node Invasion by Melanoma Cells Is Not Required for the Induction of Incomplete Differentiation by Tumor‐Specific CD8+ T Cells
K. Hargadon, Travis B. Goodloe, S. Woodall
2025Cancer Reports2 citations Open access
Semantic Scholar
A Bioinformatic Approach to Enhance Undergraduate Student Understanding of the Cancer-Immunity Cycle
K. Hargadon
2022Journal of Cancer Education2 citations Open access
Semantic Scholar
Whole Genome Expression Microarray Analysis of Highly Versus Poorly Tumorigenic Murine Melanoma Cell Lines Provides Insights into Factors That Regulate Tumor Growth, Metastasis, and Immunogenicity
K. Hargadon
2015Frontiers in Immunology2 citations Open access
Semantic Scholar
The Role of Tumor/Dendritic Cell Interactions in the Regulation of Anti-Tumor Immunity: The Good, the Bad, and the Ugly
K. Hargadon, Timothy N. J. Bullock
2014Frontiers in Immunology2 citations Open access
Semantic Scholar
CD8+ T Cell Dysfunction in Tumor-Draining Lymph Nodes: A Hallmark of Tumor Immune Escape That May Arise Early During the Course of Cancer Progression
K. Hargadon
2026Lymphatics1 citations Open access
Semantic Scholar
A Highly Sensitive Tissue‐specific qRT‐PCR‐based Assay for Detection of Melanoma Cells in Tumor‐Draining Lymph Nodes
K. Hargadon, Travis B. Goodloe
2025Current Protocols1 citations
Semantic Scholar
Impact pathway and gene ontology analyses of FOXC2 ‐correlated genes in melanoma reveal a role for the FOXC2 transcription factor in several oncogenic pathways and processes
K. Hargadon, Balázs Győrffy, J. Wall
2025Clinical and Translational Discovery1 citations Open access
Semantic Scholar
Editorial: Modulation of T-cell function and survival by the tumor microenvironment
K. Hargadon, Courtney M. Lappas, S. Jalali
2023Frontiers in Cell and Developmental Biology1 citations Open access
Semantic Scholar
Generation of Functional Gene Knockout Melanoma Cell Lines by CRISPR-Cas9 Gene Editing.
K. Hargadon, David Z. Bushhouse, Coleman E. Johnson, C. J. Williams
2021Methods in molecular biology1 citations
Semantic Scholar
A call for discovery: Re‐envisioning The Cancer Genome Atlas as a blueprint for a TCGA2.0—The COVID‐19 Genome Atlas
K. Hargadon
2021Clinical and Translational Discovery1 citations Open access
Semantic Scholar
Out“FOX”ing cancer: the implications of FOXC2 as a putative predictive biomarker for cancer immunotherapy
K. Hargadon
2026Frontiers in Medicine0 citations Open access
Semantic Scholar
Abstract 551: The FOXC2 transcription factor inhibitor MC-1-F2 alters the chemosensitivity of B16-F10 melanoma cells
Baylor F. Jenkins, K. Hargadon
2025Cancer Research0 citations
Semantic Scholar
Abstract 3032: Generation of a FOXC2-deficient melanoma cell line using CRISPR-Cas9 gene editing
D. Clark, Patrick D. Conde, K. Hargadon
2024Cancer Research0 citations
Semantic Scholar
Abstract 2358: Impact pathway analysis of FOXC2-correlated genes in melanoma: A meta-analysis approach to understand the tumor-promoting functions of the FOXC2 transcription factor
J. Wall, K. Hargadon
2022Cancer Research0 citations
Semantic Scholar
A Flow Cytometric Assay for Investigating Melanoma Cell Adhesion to Lymphatic Endothelial Cells.
K. Hargadon, Coleman E. Johnson
2021Methods in molecular biology0 citations
Semantic Scholar
Educating society about the unseen, but not unknown, risk factors for severe COVID-19: a step towards overcoming vaccine hesitancy through a more informed public
K. Hargadon
2021Journal of global health reports0 citations Open access
Semantic Scholar
Abstract 2617: FOXC2-associated regulation of melanoma cell adhesion to the extracellular matrix and lymphatic endothelial cells
Coleman E. Johnson, C. J. Williams, K. Hargadon
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 159: Chemokine receptor expression profiling of lymph node invasive versus lymph node non-invasive melanomas
David Z. Bushhouse, K. Hargadon
2019Tumor Biology0 citations Open access
Semantic Scholar
Abstract 2610: The FOXC2 transcription factor promotes growth of melanoma cells in bothin vitroandin vivo settings
C. J. Williams, Coleman E. Johnson, David Z. Bushhouse, K. Hargadon
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Dactyloidae : Anolis sagrei Duméril and Bibron ( Brown Anole ) and A . carolinensis
K. Hargadon, E. Carter, Rachel M. Goodman, K. Hargadon +1 more
20180 citations
Semantic Scholar
Generation of a Foxc2 Gene Knockout Murine Melanoma Cell Line via CRISPR Cas9 Genome Editing Technology
Jefferson C Thompson, K. Hargadon
2016The FASEB Journal0 citations Open access
Semantic Scholar
Validation of a Quantitative Polymerase Chain Reaction (qPCR)‐based Method for Detecting Lymph Node Metastasis by Melanoma Cells
Travis B. Goodloe, K. Hargadon
2016The FASEB Journal0 citations Open access
Semantic Scholar
Genetic Engineering of the Murine Melanoma D5.1G4 to Express a Model Antigen for Evaluation of Anti‐tumor CD8+ T Cell Responses
S. Woodall, K. Hargadon
20150 citations
Semantic Scholar
Tumor Cell/Dendritic Cell Interactions and the Influence of Tumors on Dendritic Cell-mediated Anti-Tumor Immune Responses and Dendritic Cell-Based Tumor Immunotherapies
K. Hargadon, Timothy N. J. Bullock
20140 citations Open access
Semantic Scholar
Inheritance Patterns in Monohybrid and Dihybrid Crosses for sepia eye color and apterous ( wingless ) Mutations in Drosophila melanogaster
S. Wiles, K. Hargadon
20130 citations
Semantic Scholar
Characterization of the Murine Melanoma Cell Lines B 12F 1 and D 5 . 1 G 4 : A Model System for Investigating Immune Regulation by Highly Tumorigenic versus Poorly Tumorigenic Melanomas
Pranay Reddy, K. Hargadon
20120 citations
Semantic Scholar
Major Histocompatibility Complex Class II Expression and Hemagglutinin Subtype Inﬂuence the Infectivity of Type A Inﬂuenza Virus for Respiratory Dendritic Cells (cid:1)
K. Hargadon, Hai-Xia Zhou, R. Albrecht, Haley A. Dodd +2 more
20110 citations
Semantic Scholar

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Coleman E. Johnson×6
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C. J. Williams×6
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Travis B. Goodloe×4
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David Z. Bushhouse×4

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