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Paula Pierozan · SciRah

Researcher profile · Semantic Scholar

Paula Pierozan

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Paula Pierozan — researcher profile on SciRah

h-index: 26
Works: 70
Citations: 1,934

Most-cited papers

Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.
Vera Lúcia de Liz Oliveira Cavalli, Daiane Cattani, Carla Elise Heinz Rieg, Paula Pierozan +6 more
2013Free Radical Biology & Medicine212 citations Open access
Semantic Scholar
Neutrophil apoptosis: a marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome
L. Fialkow, Luciano Fochesatto, M. Bozzetti, A. R. Milani +7 more
2006Critical Care147 citations Open access
Semantic Scholar
Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells
Paula Pierozan, F. Jernerén, Oskar Karlsson
2018Archives of Toxicology112 citations Open access
Semantic Scholar
The Choice of Euthanasia Method Affects Metabolic Serum Biomarkers
Paula Pierozan, F. Jernerén, Y. Ransome, Oskar Karlsson
2017Basic & Clinical Pharmacology & Toxicology91 citations Open access
Semantic Scholar
1α,25-dihydroxyvitamin D(3) mechanism of action: modulation of L-type calcium channels leading to calcium uptake and intermediate filament phosphorylation in cerebral cortex of young rats.
L. Zanatta, Paola Bez Goulart, Renata Gonçalves, Paula Pierozan +5 more
2012Biochimica et Biophysica Acta74 citations Open access
Semantic Scholar
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro
Paula Pierozan, Daiane Cattani, Oskar Karlsson
2020Archives of Toxicology73 citations Open access
Semantic Scholar
Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats.
Paula Pierozan, Ariane Zamoner, Ângela Krombauer Soska, R. Silvestrin +5 more
2010Experimental Neurology73 citations Open access
Semantic Scholar
PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells
Paula Pierozan, Oskar Karlsson
2017Archives of Toxicology72 citations Open access
Semantic Scholar
High-content analysis shows synergistic effects of low perfluorooctanoic acid (PFOS) and perfluorooctane sulfonic acid (PFOA) mixture concentrations on human breast epithelial cell carcinogenesis.
Paula Pierozan, M. Kosnik, Oskar Karlsson
2023Environment International63 citations Open access
Semantic Scholar
Congenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats.
Daiane Cattani, Paola Bez Goulart, Vera Lúcia de Liz Oliveira Cavalli, E. Winkelmann-Duarte +9 more
2013Molecular and Cellular Endocrinology63 citations Open access
Semantic Scholar
Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies.
Paula Pierozan, Daiane Cattani, Oskar Karlsson
2021Science of the Total Environment54 citations Open access
Semantic Scholar
Kynurenic Acid Restores Nrf2 Levels and Prevents Quinolinic Acid-Induced Toxicity in Rat Striatal Slices
F. Ferreira, Helena Biasibetti-Brendler, Paula Pierozan, F. Schmitz +4 more
2018Molecular Neurobiology47 citations Open access
Semantic Scholar
Signaling mechanisms downstream of quinolinic acid targeting the cytoskeleton of rat striatal neurons and astrocytes.
Paula Pierozan, Ariane Zamoner, Ângela Krombauer Soska, B. O. D. de Lima +4 more
2012Experimental Neurology42 citations Open access
Semantic Scholar
Neurotoxicity of Methylmercury in Isolated Astrocytes and Neurons: the Cytoskeleton as a Main Target
Paula Pierozan, Helena Biasibetti, F. Schmitz, Helena Ávila +3 more
2016Molecular Neurobiology41 citations Open access
Semantic Scholar
Quinolinic acid induces disrupts cytoskeletal homeostasis in striatal neurons. Protective role of astrocyte–neuron interaction
Paula Pierozan, F. Ferreira, B. O. D. de Lima, R. Pessoa-Pureur
2015Journal of Neuroscience Research36 citations
Semantic Scholar
Methylphenidate Decreases ATP Levels and Impairs Glutamate Uptake and Na+,K+-ATPase Activity in Juvenile Rat Hippocampus
F. Schmitz, Paula Pierozan, A. Rodrigues, Helena Biasibetti +6 more
2017Molecular Neurobiology34 citations
Semantic Scholar
Methylphenidate Causes Behavioral Impairments and Neuron and Astrocyte Loss in the Hippocampus of Juvenile Rats
F. Schmitz, Paula Pierozan, A. Rodrigues, Helena Biasibetti +6 more
2016Molecular Neurobiology34 citations Open access
Semantic Scholar
Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases
L. Heimfarth, S. Loureiro, Paula Pierozan, B. O. D. de Lima +3 more
2013Metabolic brain disease33 citations
Semantic Scholar
Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity.
Paula Pierozan, Oskar Karlsson
2021Toxicology Letters32 citations Open access
Semantic Scholar
Hypoxanthine Induces Neuroenergetic Impairment and Cell Death in Striatum of Young Adult Wistar Rats
Helena Biasibetti-Brendler, F. Schmitz, Paula Pierozan, B. Zanotto +4 more
2017Molecular Neurobiology30 citations
Semantic Scholar
Hypoxanthine Intrastriatal Administration Alters Neuroinflammatory Profile and Redox Status in Striatum of Infant and Young Adult Rats
Helena Biasibetti, Paula Pierozan, A. Rodrigues, V. Manfredini +1 more
2017Molecular Neurobiology30 citations
Semantic Scholar
Quinolinic acid neurotoxicity: Differential roles of astrocytes and microglia via FGF-2-mediated signaling in redox-linked cytoskeletal changes.
Paula Pierozan, Helena Biasibetti, F. Schmitz, Helena Ávila +4 more
2016Biochimica et Biophysica Acta30 citations Open access
Semantic Scholar
In vivo experimental evidence that the major metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency induce oxidative stress in striatum of developing rats: a potential pathophysiological mechanism of striatal damage in this disorder.
C. Fernandes, M. D. da Rosa, Bianca Seminotti, Paula Pierozan +5 more
2013Molecular Genetics and Metabolism28 citations
Semantic Scholar
Adult Exposure to Di-N-Butyl Phthalate (DBP) Induces Persistent Effects on Testicular Cell Markers and Testosterone Biosynthesis in Mice
Liselott Källsten, Radwa Almamoun, Paula Pierozan, E. Nylander +3 more
2022International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
The phosphorylation status and cytoskeletal remodeling of striatal astrocytes treated with quinolinic acid.
Paula Pierozan, F. Ferreira, Bárbara Ortiz de Lima, Carolina Gonçalves Fernandes +5 more
2014Experimental Cell Research26 citations
Semantic Scholar
Biochemical, histopathological and behavioral alterations caused by intrastriatal administration of quinolic acid to young rats
Paula Pierozan, C. Fernandes, M. F. Dutra, P. Pandolfo +5 more
2014The FEBS Journal26 citations
Semantic Scholar
Di-n-Butyl Phthalate and Its Monoester Metabolite Impairs Steroid Hormone Biosynthesis in Human Cells: Mechanistic In Vitro Studies
Liselott Källsten, Paula Pierozan, Jonathan W. Martin, Oskar Karlsson
2022Cells25 citations Open access
Semantic Scholar
Vimentin phosphorylation as a target of cell signaling mechanisms induced by 1alpha,25-dihydroxyvitamin D3 in immature rat testes.
Ariane Zamoner, Paula Pierozan, L. F. Vidal, Bruna Arcce Lacerda +3 more
2008Steroids24 citations
Semantic Scholar
Chronic Treatment with a Clinically Relevant Dose of Methylphenidate Increases Glutamate Levels in Cerebrospinal Fluid and Impairs Glutamatergic Homeostasis in Prefrontal Cortex of Juvenile Rats
F. Schmitz, Paula Pierozan, A. Rodrigues, Helena Biasibetti +8 more
2016Molecular Neurobiology23 citations
Semantic Scholar
Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylation
Paula Pierozan, Daiane Cattani, Oskar Karlsson
2020Cell Death and Disease22 citations Open access
Semantic Scholar
Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation
Paula Pierozan, Oskar Karlsson
2019Cell Death and Disease21 citations Open access
Semantic Scholar
Kynurenic Acid Prevents Cytoskeletal Disorganization Induced by Quinolinic Acid in Mixed Cultures of Rat Striatum
Paula Pierozan, Helena Biasibetti-Brendler, F. Schmitz, F. Ferreira +2 more
2017Molecular Neurobiology21 citations Open access
Semantic Scholar
Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
Paula Pierozan, Liselott Källsten, E. Theodoropoulou, Radwa Almamoun +1 more
2023Science of the Total Environment20 citations Open access
Semantic Scholar
Synergistic Toxicity of the Neurometabolites Quinolinic Acid and Homocysteine in Cortical Neurons and Astrocytes: Implications in Alzheimer’s Disease
Paula Pierozan, Helena Biasibetti-Brendler, F. Schmitz, F. Ferreira +2 more
2018Neurotoxicity research20 citations
Semantic Scholar
Cytoskeleton as a Target of Quinolinic Acid Neurotoxicity: Insight from Animal Models
Paula Pierozan, R. Pessoa-Pureur
2017Molecular Neurobiology18 citations
Semantic Scholar
D-Galactose Causes Motor Coordination Impairment, and Histological and Biochemical Changes in the Cerebellum of Rats
A. Rodrigues, Helena Biasibetti, B. Zanotto, E. Sanches +7 more
2017Molecular Neurobiology17 citations Open access
Semantic Scholar
Calcium signaling mechanisms disrupt the cytoskeleton of primary astrocytes and neurons exposed to diphenylditelluride.
L. Heimfarth, Fernanda da Silva Ferreira, Paula Pierozan, S. Loureiro +4 more
2016Biochimica et Biophysica Acta16 citations
Semantic Scholar
Acute intrastriatal injection of quinolinic acid provokes long-lasting misregulation of the cytoskeleton in the striatum, cerebral cortex and hippocampus of young rats.
Paula Pierozan, Carolina Gonçalves Fernandes, F. Ferreira, R. Pessoa-Pureur
2014Brain Research16 citations Open access
Semantic Scholar
Long-Term Effects of Perinatal Exposure to a Glyphosate-Based Herbicide on Melatonin Levels and Oxidative Brain Damage in Adult Male Rats
Daiane Cattani, Paula Pierozan, Ariane Zamoner, E. Brittebo +1 more
2023Antioxidants15 citations Open access
Semantic Scholar
Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice.
Radwa Almamoun, Paula Pierozan, L. Manoharan, Oskar Karlsson
2023Ecotoxicology and Environmental Safety15 citations Open access
Semantic Scholar
Toxic Synergism Between Quinolinic Acid and Glutaric Acid in Neuronal Cells Is Mediated by Oxidative Stress: Insights to a New Toxic Model
Paula Pierozan, A. L. Colín-González, Helena Biasibetti, J. C. da Silva +3 more
2017Molecular Neurobiology15 citations Open access
Semantic Scholar
Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na+,K+-ATPase Expression/Content in Brain of Rat Offspring
B. M. Schweinberger, A. Rodrigues, Elias Turcatel, Paula Pierozan +8 more
2018Molecular Neurobiology14 citations
Semantic Scholar
Methylphenidate disrupts cytoskeletal homeostasis and reduces membrane-associated lipid content in juvenile rat hippocampus
F. Schmitz, Paula Pierozan, Helena Biasibetti-Brendler, F. Ferreira +4 more
2017Metabolic brain disease13 citations
Semantic Scholar
Astrocyte-neuron interaction in diphenyl ditelluride toxicity directed to the cytoskeleton.
L. Heimfarth, Fernanda da Silva Ferreira, Paula Pierozan, M. Mingori +3 more
2017Toxicology12 citations
Semantic Scholar
The cyanobacterial neurotoxin β-N-methylamino-l-alanine (BMAA) targets the olfactory bulb region
Paula Pierozan, Elena Piras, E. Brittebo, Oskar Karlsson
2020Archives of Toxicology11 citations Open access
Semantic Scholar
The environmental neurotoxin β‐N‐methylamino‐L‐alanine inhibits melatonin synthesis in primary pinealocytes and a rat model
Paula Pierozan, M. Andersson, I. Brandt, Oskar Karlsson
2018Journal of Pineal Research11 citations
Semantic Scholar
Vitamin D3 Reverses the Hippocampal Cytoskeleton Imbalance But Not Memory Deficits Caused by Ovariectomy in Adult Wistar Rats
C. Siebert, Paula Pierozan, J. Kolling, T. D. dos Santos +8 more
2017Neuromolecular medicine10 citations
Semantic Scholar
High postnatal susceptibility of hippocampal cytoskeleton in response to ethanol exposure during pregnancy and lactation.
K. P. Reis, L. Heimfarth, Paula Pierozan, F. Ferreira +4 more
2015Alcohol10 citations
Semantic Scholar
Intracerebroventricular d‐galactose administration impairs memory and alters activity and expression of acetylcholinesterase in the rat
A. Rodrigues, Helena Biasibetti, Bruna Stela Zanotto, E. Sanches +6 more
2016International Journal of Developmental Neuroscience9 citations Open access
Semantic Scholar
NMDA Receptors and Oxidative Stress Induced by the Major Metabolites Accumulating in HMG Lyase Deficiency Mediate Hypophosphorylation of Cytoskeletal Proteins in Brain From Adolescent Rats: Potential Mechanisms Contributing to the Neuropathology of This Disease
C. Fernandes, Paula Pierozan, Gilberto Machado Soares, F. Ferreira +5 more
2015Neurotoxicity research8 citations
Semantic Scholar

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R. Pessoa-Pureur×21
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Oskar Karlsson×15
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F. Schmitz×12
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Ariane Zamoner×7

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Daiane Cattani×6

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