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K. Tahlan · SciRah

Researcher profile · Semantic Scholar

K. Tahlan

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K. Tahlan — researcher profile on SciRah

h-index: 21
Works: 61
Citations: 2,820

Most-cited papers

Minimum Information about a Biosynthetic Gene cluster
M. Medema, R. Kottmann, P. Yilmaz, M. Cummings +150 more
2015Nature Chemical Biology819 citations Open access
Semantic Scholar
SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
K. Tahlan, Regina Wilson, David B. Kastrinsky, Kriti Arora +7 more
2012Antimicrobial Agents and Chemotherapy457 citations Open access
Semantic Scholar
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis
Keriann M. Backus, H. Boshoff, C. Barry, Omar Boutureira +7 more
2011Nature Chemical Biology205 citations Open access
Semantic Scholar
Initiation of actinorhodin export in Streptomyces coelicolor
K. Tahlan, S. Ahn, Anson Sing, Tetyana D. Bodnaruk +3 more
2007Molecular Microbiology148 citations Open access
Semantic Scholar
A community resource for paired genomic and metabolomic data mining
M. Schorn, S. Verhoeven, L. Ridder, Florian Huber +106 more
2021Nature Chemical Biology115 citations Open access
Semantic Scholar
Biosynthesis and Recycling of Nicotinamide Cofactors in Mycobacterium tuberculosis
H. Boshoff, Xia Xu, K. Tahlan, Cynthia S. Dowd +8 more
2008Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA.
A. Willems, K. Tahlan, T. Taguchi, Kun-xiao Zhang +4 more
2008Journal of Molecular Biology71 citations Open access
Semantic Scholar
Klebsiella Species Associated with Bovine Mastitis in Newfoundland
M. P. Podder, L. Rogers, P. Daley, G. Keefe +2 more
2014PLoS ONE70 citations Open access
Semantic Scholar
Origins of the β-lactam rings in natural products
K. Tahlan, S. Jensen
2013Journal of antibiotics (Tokyo. 1968)69 citations
Semantic Scholar
A Two-Step Mechanism for the Activation of Actinorhodin Export and Resistance in Streptomyces coelicolor
Ye Xu, A. Willems, Catherine Au-yeung, K. Tahlan +1 more
2012mBio60 citations Open access
Semantic Scholar
Expression of ccaR, Encoding the Positive Activator of Cephamycin C and Clavulanic Acid Production in Streptomyces clavuligerus, Is Dependent on bldG
D. Bignell, K. Tahlan, Kimberley R. Colvin, S. Jensen +1 more
2005Antimicrobial Agents and Chemotherapy57 citations Open access
Semantic Scholar
Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus
K. Tahlan, H. Park, A. Wong, P. Beatty +1 more
2004Antimicrobial Agents and Chemotherapy55 citations Open access
Semantic Scholar
Ligand recognition by ActR, a TetR-like regulator of actinorhodin export.
K. Tahlan, Zhou Yu, Ye Xu, A. Davidson +1 more
2008Journal of Molecular Biology49 citations
Semantic Scholar
5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus.
K. Tahlan, C. Anders, A. Wong, R. H. Mosher +7 more
2007Chemistry and Biology41 citations Open access
Semantic Scholar
The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus
K. Tahlan, C. Anders, S. Jensen
2004Journal of Bacteriology32 citations Open access
Semantic Scholar
Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus.
K. Tahlan, H. Park, S. Jensen
2004Canadian Journal of Microbiology (print)32 citations
Semantic Scholar
Genomic and Metabolomic Analysis of the Potato Common Scab Pathogen Streptomyces scabiei
Jingyu Liu, L. Nothias, P. Dorrestein, K. Tahlan +1 more
2021ACS Omega31 citations Open access
Semantic Scholar
Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen Streptomyces sp. 11-1-2
G. Díaz-Cruz, Jingyu Liu, K. Tahlan, D. Bignell
2022Microbiology spectrum29 citations Open access
Semantic Scholar
Genome-Wide Diversity and Phylogeography of Mycobacterium avium subsp. paratuberculosis in Canadian Dairy Cattle
C. Ahlstrom, H. Barkema, K. Stevenson, R. Zadoks +11 more
2016PLoS ONE28 citations Open access
Semantic Scholar
Investigation of Transcription Repression and Small-Molecule Responsiveness by TetR-Like Transcription Factors Using a Heterologous Escherichia coli-Based Assay
S. Ahn, K. Tahlan, Zhou Yu, J. Nodwell
2007Journal of Bacteriology26 citations Open access
Semantic Scholar
Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism
Nader AbuSara, Brandon M. Piercey, M. Moore, A. Shaikh +6 more
2019Frontiers in Microbiology25 citations Open access
Semantic Scholar
TxtH is a key component of the thaxtomin biosynthetic machinery in the potato common scab pathogen Streptomyces scabies
Yu-Ting Li, Jingyu Liu, Damilola O. Adekunle, Luke Bown +2 more
2019Molecular plant pathology23 citations Open access
Semantic Scholar
Specialized Metabolites from Ribosome Engineered Strains of Streptomyces clavuligerus
A. Shaikh, L. Nothias, S. Srivastava, P. Dorrestein +1 more
2021Metabolites21 citations Open access
Semantic Scholar
Proteomics analysis of global regulatory cascades involved in clavulanic acid production and morphological development in Streptomyces clavuligerus
N. L. Ferguson, L. Peña-Castillo, M. Moore, D. Bignell +1 more
2016Journal of Industrial Microbiology & Biotechnology21 citations
Semantic Scholar
Bacterial Transmembrane Proteins that Lack N-Terminal Signal Sequences
A. Craney, K. Tahlan, D. Andrews, J. Nodwell
2011PLoS ONE20 citations Open access
Semantic Scholar
Methods for Detecting Mycobacterial Mixed Strain Infections–A Systematic Review
Alexander S. Byrne, Alex Goudreau, N. Bissonnette, I. Shamputa +1 more
2020Frontiers in Genetics19 citations Open access
Semantic Scholar
Production of Plant-Associated Volatiles by Select Model and Industrially Important Streptomyces spp.
Zhen-Long Cheng, S. McCann, N. Faraone, Jody-Ann Clarke +4 more
2020Microorganisms18 citations Open access
Semantic Scholar
Genomic epidemiology of Mycobacterium avium subsp. paratuberculosis isolates from Canadian dairy herds provides evidence for multiple infection events
Alexander S. Byrne, S. Ollier, K. Tahlan, Franck Biet +1 more
2023Frontiers in Genetics17 citations Open access
Semantic Scholar
Analysis of Streptomyces Volatilomes Using Global Molecular Networking Reveals the Presence of Metabolites with Diverse Biological Activities
Jingyu Liu, Jody-Ann Clarke, Sean M McCann, N. K. Hillier +1 more
2022Microbiology spectrum16 citations Open access
Semantic Scholar
Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets, and Associated Mechanisms of Resistance
Luke Bown, S. Srivastava, Brandon M. Piercey, C. McIsaac +1 more
2017Journal of Membrane Biology16 citations
Semantic Scholar
Use of the native flp gene to generate in-frame unmarked mutations in Streptomyces spp.
N. Zelyas, K. Tahlan, S. Jensen
2009Gene16 citations
Semantic Scholar
Genetics and Molecular Biology of Industrial Organisms -review Δ‑(l‑α‑aminoadipyl)‑l‑cysteinyl‑d‑valine Synthetase (acvs): Discovery and Perspectives
K. Tahlan, M. Moore, S. Jensen
16 citations
Semantic Scholar
Anthropogenic contamination sources drive differences in antimicrobial-resistant Escherichia coli in three urban lakes
J. Wight, Alexander S. Byrne, K. Tahlan, Andrew S. Lang
2024Applied and Environmental Microbiology15 citations Open access
Semantic Scholar
Regulation of Coronafacoyl Phytotoxin Production by the PAS-LuxR Family Regulator CfaR in the Common Scab Pathogen Streptomyces scabies
Zhen-Long Cheng, Luke Bown, K. Tahlan, D. Bignell
2015PLoS ONE15 citations Open access
Semantic Scholar
Examination of Mycobacterium avium subspecies paratuberculosis mixed genotype infections in dairy animals using a whole genome sequencing approach
Fraser W. Davidson, C. Ahlstrom, J. De Buck, H. Whitney +1 more
2016PeerJ12 citations Open access
Semantic Scholar
Genome Sequences of Klebsiella variicola Isolates from Dairy Animals with Bovine Mastitis from Newfoundland, Canada
Fraser W. Davidson, H. Whitney, K. Tahlan
2015Genome Announcements10 citations Open access
Semantic Scholar
Typing of Mycobacterium avium Subspecies paratuberculosis Isolates from Newfoundland Using Fragment Analysis
M. P. Podder, S. Banfield, G. Keefe, H. Whitney +1 more
2015PLoS ONE9 citations Open access
Semantic Scholar
Systematic assessment of the reliability of quantitative PCR assays targeting IS900 for the detection of Mycobacterium avium ssp. paratuberculosis presence in animal and environmental samples.
N. Bissonnette, J.-P. Brousseau, S. Ollier, A. Byrne +2 more
2024Journal of Dairy Science8 citations Open access
Semantic Scholar
Mechanisms and Implications of Phenotypic Switching in Bacterial Pathogens.
Alexander S. Byrne, Nathalie Bissonnette, K. Tahlan
2024Canadian Journal of Microbiology (print)7 citations
Semantic Scholar
Investigating in vivo Mycobacterium avium subsp. paratuberculosis microevolution and mixed strain infections
Alexander S. Byrne, N. Bissonnette, S. Ollier, K. Tahlan
2023Microbiology spectrum6 citations Open access
Semantic Scholar
In vivo functional analysis of a class A β-lactamase-related protein essential for clavulanic acid biosynthesis in Streptomyces clavuligerus
S. Srivastava, Kelcey S. King, Nader AbuSara, Chelsea J Malayny +3 more
2019PLoS ONE6 citations Open access
Semantic Scholar
5S Clavam Biosynthesis Is Controlled by an Atypical Two-Component Regulatory System in Streptomyces clavuligerus
Thomas Kwong, N. Zelyas, H. Cai, K. Tahlan +2 more
2012Antimicrobial Agents and Chemotherapy6 citations Open access
Semantic Scholar
Discovery and mechanistic characterization of a probiotic-origin 3β-OH-Δ5-6-cholesterol-5β-reductase directly converting cholesterol to coprostanol
Urmila Netter, Vishakha Bisht, Amit Gaurav, Rekha Sharma +9 more
2024bioRxiv5 citations Open access
Semantic Scholar
Effects of storage conditions on the microbiota of fecal samples collected from dairy cattle
A. S. Jaramillo-Jaramillo, J. T. McClure, Henrik Stryhn, K. Tahlan +1 more
2024PLoS ONE5 citations
Semantic Scholar
Systematic evaluation and optimization of TaqMan qPCR assays targeting F57, ISMAP02, and IS900 for multiplex detection of Mycobacterium avium subsp. paratuberculosis
Nathalie Bissonnette, S. Ollier, J.-P. Brousseau, A. Byrne +2 more
2025Journal of Clinical Microbiology3 citations Open access
Semantic Scholar
Carboxyethylarginine Synthase Genes Show Complex Cross-Regulation in Streptomyces clavuligerus
Thomas Kwong, K. Tahlan, C. Anders, S. Jensen
2012Applied and Environmental Microbiology3 citations Open access
Semantic Scholar
Mechanisms underlying mycobacterial infections
H. Boshoff, K. Tahlan
2010Drug Discovery Today : Disease Mechanisms3 citations Open access
Semantic Scholar
New cell wall biosynthesis inhibitors under active development for tuberculosis
K. Tahlan, H. Boshoff
2009Drugs of the future3 citations
Semantic Scholar
Transcriptional and translational analysis of the ccaR gene from Streptomyces clavuligerus.
Li-Ru Wang, K. Tahlan, Tracy L. Kaziuk, Dylan C. Alexander +1 more
2004Microbiology3 citations Open access
Semantic Scholar
Functional Cross-Talk of MbtH-Like Proteins During Thaxtomin Biosynthesis in the Potato Common Scab Pathogen Streptomyces scabiei
Yu-Ting Li, K. Tahlan, D. Bignell
2020Frontiers in Microbiology2 citations Open access
Semantic Scholar

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