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M. Hashimura · SciRah

Researcher profile · Semantic Scholar

M. Hashimura

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M. Hashimura — researcher profile on SciRah

h-index: 25
Works: 66
Citations: 1,720

Most-cited papers

β-Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis
M. Saegusa, M. Hashimura, Tsutomu Yoshida, I. Okayasu
2001British Journal of Cancer191 citations Open access
Semantic Scholar
Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug.
M. Saegusa, M. Hashimura, T. Kuwata, I. Okayasu
2009American Journal of Pathology99 citations Open access
Semantic Scholar
The possible role of bcl–2 expression in the progression of tumors of the uterine cervix
M. Saegusa, Y. Takano, M. Hashimura, Youko Shoji +1 more
1995Cancer75 citations Open access
Semantic Scholar
Transcriptional up-regulation of Sox9 by NF-κB in endometrial carcinoma cells, modulating cell proliferation through alteration in the p14(ARF)/p53/p21(WAF1) pathway.
M. Saegusa, M. Hashimura, Erina Suzuki, Tsutomu Yoshida +1 more
2012American Journal of Pathology68 citations
Semantic Scholar
HPV type 16 in conjunctival and junctional papilloma, dysplasia, and squamous cell carcinoma.
M. Saegusa, Y. Takano, M. Hashimura, I. Okayasu +1 more
1995Journal of Clinical Pathology64 citations Open access
Semantic Scholar
Upregulation of TCF4 expression as a transcriptional target of β-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells
M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano +1 more
2005Laboratory Investigation63 citations Open access
Semantic Scholar
β-Catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells
M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano +1 more
200463 citations Open access
Semantic Scholar
Transcriptional upregulation of HIF-1α by NF-κB/p65 and its associations with β-catenin/p300 complexes in endometrial carcinoma cells
Tsutomu Yoshida, M. Hashimura, Toshihide Mastumoto, Y. Tazo +3 more
2013Laboratory Investigation58 citations Open access
Semantic Scholar
Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas
M. Saegusa, M. Hashimura, T. Kuwata
2012Laboratory Investigation56 citations Open access
Semantic Scholar
Crosstalk between NF‐κB/p65 and β‐catenin/TCF4/p300 signalling pathways through alterations in GSK‐3β expression during trans‐differentiation of endometrial carcinoma cells
M. Saegusa, M. Hashimura, Takeshi Kuwata, M. Hamano +1 more
2007Journal of Pathology55 citations
Semantic Scholar
CD44 expression in normal, hyperplastic, and malignant endometrium
M. Saegusa, M. Hashimura, I. Okayasu
1998Journal of Pathology54 citations
Semantic Scholar
CD44 expression in benign, premalignant, and malignant ovarian neoplasms: relation to tumour development and progression
M. Saegusa, Daisuke Machida, M. Hashimura, I. Okayasu
1999Journal of Pathology53 citations
Semantic Scholar
TGF‐β‐mediated LEFTY/Akt/GSK‐3β/Snail axis modulates epithelial‐mesenchymal transition and cancer stem cell properties in ovarian clear cell carcinomas
Toshihide Matsumoto, Ako Yokoi, M. Hashimura, Yasuko Oguri +2 more
2018Molecular Carcinogenesis52 citations
Semantic Scholar
Down‐regulation of CD44 standard and variant isoforms during the development and progression of uterine cervical tumours
M. Saegusa, M. Hashimura, Daisuke Machida, I. Okayasu
1999Journal of Pathology48 citations
Semantic Scholar
S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma
M. Tochimoto, Yasuko Oguri, M. Hashimura, Ryo Konno +4 more
2019Laboratory Investigation41 citations Open access
Semantic Scholar
Absence of human papillomavirus genomic sequences detected by the polymerase chain reaction in oesophageal and gastric carcinomas in Japan.
M. Saegusa, M. Hashimura, Y. Takano, M. Ohbu +1 more
1997Molecular Pathology41 citations Open access
Semantic Scholar
Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma
H. Inoue, Hiroyuki Takahashi, M. Hashimura, K. Eshima +3 more
2016BMC Cancer38 citations Open access
Semantic Scholar
A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas.
M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano +2 more
2007Carcinogenesis38 citations Open access
Semantic Scholar
Transcription factor Egr1 acts as an upstream regulator of β‐catenin signalling through up‐regulation of TCF4 and p300 expression during trans‐differentiation of endometrial carcinoma cells
M. Saegusa, M. Hashimura, Takeshi Kuwata, M. Hamano +3 more
2008Journal of Pathology35 citations
Semantic Scholar
Down‐regulation of p27Kip1 expression is correlated with increased cell proliferation but not expression of p21waf1 and p53, and human papillomavirus infection in benign and malignant tumours of sinonasal regions
M. Saegusa, H. Nitta, M. Hashimura, Isao Okayasu
1999Histopathology33 citations
Semantic Scholar
Induction of p16INK4A mediated by β‐catenin in a TCF4‐independent manner: Implications for alterations in p16INK4A and pRb expression during trans‐differentiation of endometrial carcinoma cells
M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano +1 more
2006International Journal of Cancer27 citations
Semantic Scholar
Detection of the Epstein‐Barr virus genome in cervical neoplasia is closely related to the degree of infiltrating lymphoid cells: A polymerase chain reaction and in situ hybridization approach
Yoko Shojl, M. Saegusa, Y. Takano, M. Hashimura +1 more
1997Pathology international (Print)27 citations
Semantic Scholar
ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation
Risako Chiba, Masashi Akiya, M. Hashimura, Yasuko Oguri +3 more
2017PLoS ONE26 citations Open access
Semantic Scholar
Functional role of ALK-related signal cascades on modulation of epithelial-mesenchymal transition and apoptosis in uterine carcinosarcoma
H. Inoue, M. Hashimura, Masashi Akiya, Risako Chiba +1 more
2017Molecular Cancer25 citations Open access
Semantic Scholar
Pin1 acts as a modulator of cell proliferation through alteration in NF‐κB but not β‐catenin/TCF4 signalling in a subset of endometrial carcinoma cells
M. Saegusa, M. Hashimura, T. Kuwata
2010Journal of Pathology25 citations
Semantic Scholar
Loss of expression of the gene deleted in colon carcinoma (DCC) is closely related to histologic differentiation and lymph node metastasis in endometrial carcinoma
M. Saegusa, M. Hashimura, A. Hara, I. Okayasu
1999Cancer25 citations Open access
Semantic Scholar
FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma
T. Nishi, Hiroyuki Takahashi, M. Hashimura, Tsutomu Yoshida +2 more
2015Cancer Medicine23 citations Open access
Semantic Scholar
Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells.
M. Saegusa, M. Hashimura, T. Kuwata, M. Hamano +1 more
2004American Journal of Pathology23 citations
Semantic Scholar
Up‐regulation and nuclear localization of β‐catenin in endometrial carcinoma in response to progesterone therapy
M. Saegusa, M. Hamano, T. Kuwata, Tsutomu Yoshida +5 more
2003Cancer Science22 citations Open access
Semantic Scholar
A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma
M. Inukai, Ako Yokoi, Yuuki Ishizuka, M. Hashimura +7 more
2021Cell Communication and Signaling18 citations Open access
Semantic Scholar
S100A4/non-muscle myosin IIA/p53 axis contributes to aggressive features in ovarian high-grade serous carcinoma.
A. Hîruța, Yasuko Oguri, Ako Yokoi, Toshihide Matsumoto +7 more
2020American Journal of Pathology18 citations Open access
Semantic Scholar
PTEN overexpression and nuclear β-catenin stabilization promote morular differentiation through induction of epithelial–mesenchymal transition and cancer stem cell-like properties in endometrial carcinoma
Ako Yokoi, Marina Minami, M. Hashimura, Yasuko Oguri +9 more
2022Cell Communication and Signaling17 citations Open access
Semantic Scholar
The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas
A. Hara, M. Hashimura, Koji Tsutsumi, Masashi Akiya +3 more
2016Cancer Medicine17 citations Open access
Semantic Scholar
Transcriptional regulation of pro‐apoptotic Par‐4 by NF‐κB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis
M. Saegusa, M. Hashimura, T. Kuwata, I. Okayasu
2010Journal of Pathology17 citations
Semantic Scholar
Anaplastic lymphoma kinase (ALK) overexpression is associated with aggressive phenotypic characteristics of ovarian high-grade serous carcinoma.
Toshihide Matsumoto, Y. Oda, Y. Hasegawa, M. Hashimura +7 more
2021American Journal of Pathology16 citations Open access
Semantic Scholar
Possible role of nuclear β‐catenin in resistance to preoperative chemoradiotherapy in locally advanced rectal cancer
Hiroyuki Takahashi, Kie Nakamura, Akane Usami, Tomoko Tsuruta +3 more
2017Histopathology16 citations
Semantic Scholar
Mixed angiosarcoma, clear cell adenocarcinoma and mature teratoma elements in an ovarian tumor: A case report and literature review
Hiroyuki Takahashi, Pattama Chaopotong, S. Kajita, M. Hashimura +2 more
2012Pathology international (Print)16 citations
Semantic Scholar
A combination of stromal PD‐L1 and tumoral nuclear β‐catenin expression as an indicator of colorectal carcinoma progression and resistance to chemoradiotherapy in locally advanced rectal carcinoma
Hiroyuki Takahashi, Hironori Watanabe, M. Hashimura, Toshihide Matsumoto +6 more
2022The Journal of Pathology: Clinical Research15 citations Open access
Semantic Scholar
Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma
Mayu Nakagawa, Toshihide Matsumoto, Ako Yokoi, M. Hashimura +9 more
2023Molecular Oncology11 citations Open access
Semantic Scholar
A functional role of LEFTY during progesterone therapy for endometrial carcinoma
Wu Fei, Daiki Kijima, Mami Hashimoto, M. Hashimura +5 more
2017Cell Communication and Signaling11 citations Open access
Semantic Scholar
Transcriptional regulation of the alpha-1 type II collagen gene by nuclear factor B/p65 and Sox9 in the chondrocytic phenotype of uterine carcinosarcomas.
Tsutomu Yoshida, M. Hashimura, T. Kuwata, Toshihide Matsumoto +5 more
2013Human Pathology11 citations
Semantic Scholar
Up‐regulation of pS2 expression during the development of adenocarcinomas but not squamous cell carcinomas of the uterine cervix, independently of expression of c‐jun or oestrogen and progesterone receptors
M. Saegusa, M. Hashimura, A. Hara, I. Okayasu
2000Journal of Pathology11 citations
Semantic Scholar
Cytoplasmic EBP50 and elevated PARP1 are unfavorable prognostic factors in ovarian clear cell carcinoma.
Toshihide Matsumoto, Ako Yoki, Ryo Konno, Yasuko Oguri +8 more
2021Carcinogenesis10 citations
Semantic Scholar
Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma
Toshihide Matsumoto, Hiromi Chino, Masashi Akiya, M. Hashimura +5 more
2020Molecular Carcinogenesis9 citations
Semantic Scholar
Nuclear survivin is associated with cell proliferative advantage in uterine cervical carcinomas during radiation therapy
Pattama Chaopotong, S. Kajita, M. Hashimura, M. Saegusa
2012Journal of Clinical Pathology9 citations
Semantic Scholar
S100A4 contributes to colorectal carcinoma aggressive behavior and to chemoradiotherapy resistance in locally advanced rectal carcinoma
Yohei Harada, Sayako Ikeda, Yuna Kawabe, Yasuko Oguri +9 more
2024Scientific Reports7 citations Open access
Semantic Scholar
Nodal induces apoptosis and inhibits proliferation in ovarian endometriosis-clear cell carcinoma lesions
R. Miura, Ako Yokoi, Toshihide Matsumoto, Yasuko Oguri +4 more
2019BMC Cancer6 citations Open access
Semantic Scholar
A complex interplay between Notch effectors and β-catenin signaling in morular differentiation of endometrial carcinoma cells.
Ako Yokoi, Akari Murayama, M. Hashimura, Yasuko Oguri +6 more
2023American Journal of Pathology5 citations Open access
Semantic Scholar
Nucleobindin-2 mediates TGF-β1-driven phenotypes in ZEB1-high uterine carcinosarcoma.
Yui Kobayashi, Ako Yokoi, M. Hashimura, Yasuko Oguri +11 more
2023American Journal of Pathology5 citations
Semantic Scholar
EBP50 Depletion and Nuclear β-Catenin Accumulation Engender Aggressive Behavior of Colorectal Carcinoma through Induction of Tumor Budding
T. Itou, Y. Ishibashi, Yasuko Oguri, M. Hashimura +7 more
2023Cancers5 citations Open access
Semantic Scholar

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M. Saegusa×50
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M. Saegusa — researcher profile on SciRah
I. Okayasu×18
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I. Okayasu — researcher profile on SciRah
Toshihide Matsumoto×16
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Toshihide Matsumoto — researcher profile on SciRah
Ako Yokoi×15
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Ako Yokoi — researcher profile on SciRah

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Yasuko Oguri — researcher profile on SciRah

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T. Kuwata — researcher profile on SciRah

Mayu Nakagawa×9

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Mayu Nakagawa — researcher profile on SciRah

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M. Hamano — researcher profile on SciRah

M. Tochimoto×7

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M. Tochimoto — researcher profile on SciRah

Y. Ishibashi×7

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Y. Ishibashi — researcher profile on SciRah

Tsutomu Yoshida×6

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Tsutomu Yoshida — researcher profile on SciRah

Masashi Akiya×6

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Masashi Akiya — researcher profile on SciRah