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Macarena S. Arrázola · SciRah

Researcher profile · Semantic Scholar

Macarena S. Arrázola

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Macarena S. Arrázola — researcher profile on SciRah

h-index: 17
Works: 33
Citations: 1,022

Most-cited papers

Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease
M. Dinamarca, J. P. Sagal, R. Quintanilla, J. Godoy +2 more
2010Molecular Neurodegeneration115 citations Open access
Semantic Scholar
Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice
C. Tapia-Rojas, C. Lindsay, C. Montecinos-Oliva, Macarena S. Arrázola +4 more
2015Molecular Neurodegeneration89 citations Open access
Semantic Scholar
Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics
C. Silva‐Alvarez, Macarena S. Arrázola, J. Godoy, Daniela Ordenes +1 more
2013Frontiers in Cellular Neuroscience88 citations Open access
Semantic Scholar
Nicotine Prevents Synaptic Impairment Induced by Amyloid-β Oligomers Through α7-Nicotinic Acetylcholine Receptor Activation
N. Inestrosa, J. Godoy, Jessica Y. Vargas, Macarena S. Arrázola +4 more
2013Neuromolecular medicine84 citations
Semantic Scholar
How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario
Macarena S. Arrázola, C. Silva‐Alvarez, N. Inestrosa
2015Frontiers in Cellular Neuroscience80 citations Open access
Semantic Scholar
Calcium/calmodulin‐dependent protein kinase type IV is a target gene of the Wnt/β‐catenin signaling pathway
Macarena S. Arrázola, Lorena Varela-Nallar, Marcela Colombres, Enrique M. Toledo +9 more
2009Journal of Cellular Physiology71 citations Open access
Semantic Scholar
Mitochondria in Developmental and Adult Neurogenesis
Macarena S. Arrázola, T. Andraini, M. Szelechowski, L. Moulédous +5 more
2018Neurotoxicity research56 citations
Semantic Scholar
Wnt-5a Ligand Modulates Mitochondrial Fission-Fusion in Rat Hippocampal Neurons*
J. Godoy, Macarena S. Arrázola, Daniela Ordenes, C. Silva‐Alvarez +2 more
2014Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Axonal Degeneration Is Mediated by Necroptosis Activation
Macarena S. Arrázola, Cristian Saquel, Romina J. Catalán, Sebastián A. Barrientos +4 more
2019Journal of Neuroscience55 citations Open access
Semantic Scholar
Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons
Macarena S. Arrázola, E. Ramos-Fernández, P. Cisternas, Daniela Ordenes +1 more
2017PLoS ONE49 citations Open access
Semantic Scholar
Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice.
M. Dinamarca, Macarena S. Arrázola, Enrique M. Toledo, W. Cerpa +2 more
2008Chemico-Biological Interactions45 citations Open access
Semantic Scholar
Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease.
Kevin Richetin, M. Moulis, A. Millet, Macarena S. Arrázola +7 more
2017Neurobiology of Disease41 citations Open access
Semantic Scholar
WASP-1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by Aβ oligomers.
Jessica Y. Vargas, Juan Ahumada, Macarena S. Arrázola, Marco Fuenzalida +1 more
2015Experimental Neurology34 citations
Semantic Scholar
Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation
Macarena S. Arrázola, Matías Lira, Felipe Véliz-Valverde, G. Quiroz +10 more
2023Aging Cell26 citations Open access
Semantic Scholar
The Protein Oxidation Repair Enzyme Methionine Sulfoxide Reductase A Modulates Aβ Aggregation and Toxicity In Vivo
A. N. Minniti, Macarena S. Arrázola, M. Bravo‐Zehnder, F. Ramos +2 more
2015Antioxidants and Redox Signaling25 citations Open access
Semantic Scholar
The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling
J. M. Chao de la Barca, Macarena S. Arrázola, C. Bocca, Laetitia Arnauné-Pelloquin +6 more
2019Scientific Reports18 citations Open access
Semantic Scholar
Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aβ Aggregation
C. Montecinos-Oliva, Macarena S. Arrázola, C. Jara, C. Tapia-Rojas +1 more
2020Pharmaceuticals17 citations Open access
Semantic Scholar
Monitoring mitochondrial membranes permeability in live neurons and mitochondrial swelling through electron microscopy analysis.
Macarena S. Arrázola, N. Inestrosa
2015Methods in molecular biology17 citations
Semantic Scholar
Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology
Macarena S. Arrázola, F. Court
2019Neural Regeneration Research14 citations Open access
Semantic Scholar
Poly(ethylene imine)-chitosan carbon dots: study of its physical–chemical properties and biological in vitro performance
Nicolás Santos, Santiago Valenzuela, Camilo Segura, Igor Osorio-Román +4 more
2023Discover Nano13 citations Open access
Semantic Scholar
Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase
E. Ramos-Fernández, Macarena S. Arrázola, C. A. Oliva, Sebastian B. Arredondo +2 more
2021Scientific Reports13 citations Open access
Semantic Scholar
Commentary on “PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons”
Macarena S. Arrázola, F. Court
2022Neural Regeneration Research10 citations Open access
Semantic Scholar
Mitochondrial OPA1 Deficiency Is Associated to Reversible Defects in Spatial Memory Related to Adult Neurogenesis in Mice
T. Andraini, Lionel Moulédous, Petnoi Petsophonsakul, Cédrick Florian +11 more
2023eNeuro9 citations Open access
Semantic Scholar
Protein Misfolding Disorders: A Trip into the ER
C. Hetz, R. Kaufman, Amy S. Lee, J. Atkin +32 more
20187 citations Open access
Semantic Scholar
Mimicking the Physicochemical Properties of the Cornea: A Low-Cost Approximation Using Highly Available Biopolymers
Juan Hernández, Concepción Panadero-Medianero, Macarena S. Arrázola, Manuel Ahumada
2024Polymers4 citations Open access
Semantic Scholar
SIRT1 Protects Dendrites, Mitochondria and Synapses from Aβ Oligomers in Hippocampal Neurons
J. Godoy, C. Allard, Macarena S. Arrázola, J. Zolezzi +1 more
20134 citations Open access
Semantic Scholar
Genetic background modulates phenotypic expressivity in OPA1 mutated mice, relevance to DOA pathogenesis
Djamaa Atamena, Venu Gurram, Petnoi Petsophonsakul, Farnoosh Khosrobakhsh +5 more
2023Frontiers in Molecular Neuroscience3 citations Open access
Semantic Scholar
Necroptosis inhibition counteracts neurodegeneration, memory decline and key hallmarks of aging, promoting brain rejuvenation
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Felipe Véliz-Valverde +11 more
2021bioRxiv1 citations Open access
Semantic Scholar
Mitochondrial OPA1 deficiency causes reversible defects in adult neurogenesis-associated spatial memory in mice
T. Andraini, L. Moulédous, Petnoi Petsophonsakul, C. Florian +11 more
2021bioRxiv1 citations Open access
Semantic Scholar
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key 1 hallmarks of aging, promoting brain rejuvenation.
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal +12 more
20211 citations
Semantic Scholar
Necroptosis inhibition counteracts neurodegeneration
Macarena S. Arrázola, Matías Lira, Felipe Véliz-Valverde, Gabriel Quiroz +11 more
20230 citations
Semantic Scholar
Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice
C. Tapia-Rojas, C. Lindsay, C. Montecinos-Oliva, Macarena S. Arrázola +4 more
2015Molecular Neurodegeneration0 citations Open access
Semantic Scholar
Role of Alzheimer's β-Amyloid on Wnt signaling
N. Inestrosa, Catalina P. Grabowski, Macarena S. Arrázola, Lorena Varela-Nallar +1 more
20090 citations Open access
Semantic Scholar
Targeting necroptosis to halt neural retina degeneration in the hOPA1delTTAG mouse model of Dominant Optic Atrophy
Macarena S. Arrázola, Concepción Panadero-Medianero, A. Iribarren
0 citations Open access
Semantic Scholar

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