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Liqi He · SciRah

Researcher profile · Semantic Scholar

Liqi He

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Liqi He — researcher profile on SciRah

h-index: 8
Works: 21
Citations: 488

Most-cited papers

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors
P. Ross-Macdonald, H. D. De Silva, Qi Guo, Hong Xiao +10 more
2008Molecular Cancer Therapeutics121 citations Open access
Semantic Scholar
4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2, 4-dichlorophenyl)pyrazolo[1,5-a]-1,3,5-triazine: a potent, orally bioavailable CRF(1) receptor antagonist.
Liqi He, P. Gilligan, R. Zaczek, L. Fitzgerald +8 more
2000Journal of Medicinal Chemistry105 citations Open access
Semantic Scholar
Non-peptide corticotropin-releasing hormone antagonists: syntheses and structure-activity relationships of 2-anilinopyrimidines and -triazines.
A. Arvanitis, P. Gilligan, R. J. Chorvat, R. S. Cheeseman +21 more
1999Journal of Medicinal Chemistry65 citations Open access
Semantic Scholar
Effects of a Non-peptide CRF Antagonist (DMP696) on the Behavioral and Endocrine Sequelae of Maternal Separation
C. Maciag, G. Dent, P. Gilligan, Liqi He +4 more
2002Neuropsychopharmacology63 citations
Semantic Scholar
The CRF1 receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats
J. Mcelroy, Kathryn A. Ward, Kim L. Zeller, Keith Jones +3 more
2002Psychopharmacology44 citations
Semantic Scholar
8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists.
P. Gilligan, Liqi He, Todd Clarke, P. Tivitmahaisoon +19 more
2009Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors.
K. Zimmermann, M. Wittman, M. Saulnier, Upender Velaparthi +17 more
2010Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Modulation of cofilin phosphorylation by inhibition of the Lim family kinases.
Liqi He, S. Seitz, G. Trainor, D. Tortolani +8 more
2012Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Structure-activity studies on 4-substituted-2-anilinopyrimidine corticotropin releasing factor (CRF) antagonists.
P. Gilligan, Liqi He, S. Culp, L. Fitzgerald +2 more
1999Bioorganic & Medicinal Chemistry8 citations
Semantic Scholar
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology.
Liqi He, Meng-Yao Zhang, Matthew Cox, Qian Zhang +24 more
2024ACS Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Yam B. Poudel, Liqi He, Matthew Cox, Qian Zhang +29 more
2024ACS Medicinal Chemistry Letters4 citations Open access
Semantic Scholar
Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach.
Yam B. Poudel, Julian C Lo, Derek J. Norris, Matthew Cox +21 more
2024ACS Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
Discovery of BMS-159, an Orally Active Imidazotriazine Pan-CK2 Inhibitor for the Treatment of Cancer.
Christine Tarby, A. Hart, H. Wan, Liqi He +31 more
2026ACS Medicinal Chemistry Letters1 citations
Semantic Scholar
Abstract 5417: The identification of BMS-595, an orally active imidazo[1,2-b]pyridazine CK2 inhibitor with in vivo anti-tumor activity
C. Tarby, Liqi He, B. Fink, Andrew J. Nation +20 more
20150 citations
Semantic Scholar
Composes pyrimidine a substitution phenyle utilises en tant qu'inhibiteurs de kinases
S. Wrobleski, Shuqun Lin, Katherina Leftheris, Liqi He +3 more
20060 citations
Semantic Scholar
antagonists Pyrazolotriazine as crf
Liqi He, P. Gilligan, R. J. Chorvat, G. Arvanitis
19990 citations
Semantic Scholar
Pyrazolotriazine as crf antagonists
G. Arvanitis, R. J. Chorvat, P. Gilligan, Liqi He
19990 citations
Semantic Scholar
Azolotriaziner and pyrimidines
A. Arvanitis, R. J. Chorvat, Liqi He, P. Gilligan +2 more
19970 citations
Semantic Scholar
Azolotriazine and pyrimidines
A. Arvanitis, R. J. Chorvat, Liqi He, P. Gilligan +2 more
19970 citations
Semantic Scholar

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