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D. Gamm · SciRah

Researcher profile · Semantic Scholar

D. Gamm

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D. Gamm — researcher profile on SciRah

h-index: 36
Works: 161
Citations: 5,370

Most-cited papers

Generation of three dimensional retinal tissue with functional photoreceptors from human iPSCs
X. Zhong, C. Gutierrez, Tian Xue, Christopher Hampton +9 more
2014Nature Communications884 citations Open access
Semantic Scholar
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines
E. Capowski, Kayvan Samimi, Steven J. Mayerl, M. Phillips +16 more
2019Development292 citations Open access
Semantic Scholar
iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.
Ruchira Singh, Wei Shen, David Kuai, Jessica Martin +15 more
2013Human Molecular Genetics217 citations Open access
Semantic Scholar
Functional analysis of serially expanded human iPS cell-derived RPE cultures.
Ruchira Singh, M. Phillips, David Kuai, Jackelyn Meyer +8 more
2013Investigative Ophthalmology and Visual Science128 citations Open access
Semantic Scholar
Drusen in patient-derived hiPSC-RPE models of macular dystrophies
Chad A. Galloway, Sonal Dalvi, Sandy S. C. Hung, Leslie A. MacDonald +10 more
2017Proceedings of the National Academy of Sciences of the United States of America114 citations Open access
Semantic Scholar
The NIH Somatic Cell Genome Editing program
Krishanu Saha, E. Sontheimer, P. Brooks, M. Dwinell +71 more
2021Nature106 citations Open access
Semantic Scholar
Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.
Debra A. Thompson, R. Ali, E. Banin, K. Branham +12 more
2015Investigative Ophthalmology and Visual Science102 citations Open access
Semantic Scholar
The use of topical insulin to treat refractory neurotrophic corneal ulcers
Angeline L. Wang, E. Weinlander, Brandon Metcalf, N. Barney +3 more
2017Cornea91 citations Open access
Semantic Scholar
Generation of Highly Enriched Populations of Optic Vesicle-Like Retinal Cells from Human Pluripotent Stem Cells
Sarah K. Ohlemacher, Clara Iglesias, Akshayalakshmi Sridhar, D. Gamm +1 more
2015Current protocols in stem cell biology90 citations Open access
Semantic Scholar
Biallelic Mutations in MITF Cause Coloboma, Osteopetrosis, Microphthalmia, Macrocephaly, Albinism, and Deafness.
A. George, Dina J. Zand, R. Hufnagel, Ruchi Sharma +9 more
2016American Journal of Human Genetics85 citations Open access
Semantic Scholar
Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae
Jorn Lakowski, Emily Welby, D. Budinger, Fabiana di Marco +6 more
2018Stem Cells82 citations Open access
Semantic Scholar
Investigating cone photoreceptor development using patient-derived NRL null retinal organoids
Alyssa Kallman, E. Capowski, Jie Wang, A. Kaushik +10 more
2020Communications Biology78 citations Open access
Semantic Scholar
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
Jonathan R. Soucy, Erika A. Aguzzi, Julie Y. Cho, M. Gilhooley +131 more
2023Molecular Neurodegeneration73 citations Open access
Semantic Scholar
Using human induced pluripotent stem cells to treat retinal disease
S. Borooah, M. Phillips, B. Bilican, Alan F. Wright +4 more
2013Progress in retinal and eye research72 citations Open access
Semantic Scholar
Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection
Benjamin Steyer, Q. Bu, Evan Cory, Ke-Er Jiang +6 more
2018Stem Cell Reports67 citations Open access
Semantic Scholar
Cone photoreceptors in human stem cell derived retinal organoids demonstrate intrinsic light responses that mimic those of primate fovea
Aindrila Saha, E. Capowski, Maria A. Fernandez Zepeda, Emma C Nelson +2 more
2022Cell Stem Cell65 citations Open access
Semantic Scholar
Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.
E. Capowski, Joseph M. Simonett, E. Clark, L. Wright +9 more
2014Human Molecular Genetics65 citations Open access
Semantic Scholar
Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration.
Ruchira Singh, David Kuai, K. Guziewicz, Jackelyn Meyer +7 more
2015Molecular Therapy63 citations Open access
Semantic Scholar
A novel approach to single cell RNA-seq analysis facilitates in silico gene reporting of human pluripotent stem cell-derived retinal cell types
M. Phillips, Peng Jiang, Sara E. Howden, Patrick Barney +12 more
2017Stem Cells61 citations Open access
Semantic Scholar
Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods
Lyndsay L. Leach, R. Croze, Qi-Rui Hu, Vignesh P Nadar +4 more
2016Journal of Ocular Pharmacology and Therapeutics60 citations Open access
Semantic Scholar
Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution
Ebrahim Aboualizadeh, M. Phillips, Juliette E. McGregor, D. Diloreto +11 more
2020Stem Cell Reports54 citations Open access
Semantic Scholar
Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy.
Divya Sinha, Benjamin Steyer, Pawan K. Shahi, Katherine P. Mueller +15 more
2020American Journal of Human Genetics51 citations Open access
Semantic Scholar
β2–Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression
Jeremy A. Lavine, M. Farnoodian, Shoujian Wang, Soesiawati R. Darjatmoko +5 more
2017Investigative Ophthalmology and Visual Science39 citations Open access
Semantic Scholar
Gene augmentation and read-through rescue channelopathy in an iPSC-RPE model of congenital blindness
Pawan K. Shahi, Dalton Hermans, Divya Sinha, S. Brar +7 more
2018bioRxiv36 citations Open access
Semantic Scholar
Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs
Ana Ripolles-Garcia, N. Dolgova, M. Phillips, S. Savina +11 more
2022Stem Cell Reports33 citations Open access
Semantic Scholar
Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin
Chad A. Galloway, Sonal Dalvi, A. M. Shadforth, Shuko Suzuki +7 more
2018Investigative Ophthalmology and Visual Science33 citations Open access
Semantic Scholar
Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications
D. Gamm, M. Phillips, Ruchira Singh
2013Expert Review of Ophthalmology33 citations Open access
Semantic Scholar
Micromolded honeycomb scaffold design to support the generation of a bilayered RPE and photoreceptor cell construct
In-Kyu Lee, Ruo-Sen Xie, Agustín Luz-Madrigal, Seunghwan Min +8 more
2023Bioactive Materials30 citations Open access
Semantic Scholar
CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids
K. Wahlin, Jie Cheng, Shawna L Jurlina, Melissa K. Jones +12 more
2021Frontiers in Cell and Developmental Biology29 citations Open access
Semantic Scholar
Ultrathin micromolded 3D scaffolds for high-density photoreceptor layer reconstruction
In-Kyu Lee, Allison L. Ludwig, M. Phillips, Juhwan Lee +6 more
2021Science Advances29 citations Open access
Semantic Scholar
Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy
M. Kabra, Pawan K. Shahi, Yuyuan Wang, Divya Sinha +13 more
2023Journal of Clinical Investigation27 citations Open access
Semantic Scholar
Outer Retinal Cell Replacement: Putting the Pieces Together
Allison L. Ludwig, D. Gamm
2021Translational Vision Science & Technology27 citations Open access
Semantic Scholar
THE ROLE OF FGF9 IN THE PRODUCTION OF NEURAL RETINA AND RPE IN A PLURIPOTENT STEM CELL MODEL OF EARLY HUMAN RETINAL DEVELOPMENT
D. Gamm, E. Clark, E. Capowski, Ruchira Singh
2019American journal of ophthalmology-glaucoma26 citations Open access
Semantic Scholar
A combined RNA-seq and whole genome sequencing approach for identification of non-coding pathogenic variants in single families
Revital Bronstein, E. Capowski, Sudeep Mehrotra, Alex D. Jansen +7 more
2019bioRxiv25 citations Open access
Semantic Scholar
Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa
Steven J. Mayerl, Simona Bajgai, Allison L. Ludwig, Lindsey D. Jager +6 more
2022Stem Cell Reports22 citations Open access
Semantic Scholar
Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures
Allison L. Ludwig, Steven J. Mayerl, Yu Gao, Mark Banghart +4 more
2023Proceedings of the National Academy of Sciences of the United States of America19 citations Open access
Semantic Scholar
Mimicking Retinal Development and Disease With Human Pluripotent Stem Cells.
Divya Sinha, J. Phillips, M. Phillips, D. Gamm
2016Investigative Ophthalmology and Visual Science18 citations Open access
Semantic Scholar
Report on the National Eye Institute Audacious Goals Initiative: Photoreceptor Regeneration and Integration Workshop.
D. Gamm, R. Wong
2015Translational Vision Science & Technology18 citations
Semantic Scholar
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing
Francesca Barone, J. Amaral, I. Bunea, M. Farnoodian +8 more
2023JCI Insight14 citations Open access
Semantic Scholar
VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures
L. Wright, I. Pinilla, Jishnu Saha, Joshua M. Clermont +5 more
2015PLoS ONE12 citations Open access
Semantic Scholar
Human photoreceptors switch from autonomous axon extension to cell-mediated process pulling during synaptic marker redistribution
Sarah K. Rempel, Madalynn J. Welch, Allison L. Ludwig, M. Phillips +4 more
2021bioRxiv10 citations Open access
Semantic Scholar
Metabolic stress and early cell death in photoreceptor precursor cells following retinal transplantation
Raghavi Sudharsan, N. Dolgova, Jennifer C Kwok, Alexa P Gray +9 more
2025Stem cell research & therapeutics9 citations Open access
Semantic Scholar
Cone photoreceptors in human stem cell-derived retinal organoids demonstrate intrinsic light responses that mimic those of primate fovea
Aindrila Saha, E. Capowski, Maria A. Fernandez Zepeda, Emma C Nelson +2 more
2022Cell Stem Cell9 citations Open access
Semantic Scholar
From embryonic stem cells to mature photoreceptors
D. Gamm, L. Wright
2013Nature Biotechnology9 citations
Semantic Scholar
Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level
Florian Udry, Sarah Decembrini, D. Gamm, N. Déglon +2 more
2020Scientific Reports8 citations Open access
Semantic Scholar
In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids.
Kayvan Samimi, B. Pattnaik, E. Capowski, Krishanu Saha +2 more
2022Biomedical Optics Express7 citations Open access
Semantic Scholar
Robust generation of photoreceptor-dominant retinal organoids from porcine induced pluripotent stem cells
Kimberly L. Edwards, Bethany Moore, Tyler-Serie Ganser, P. J. Susaimanickam +10 more
2025Stem Cell Reports6 citations Open access
Semantic Scholar
Chapter 4 - Restoring Vision to the Blind: Stem Cells and Transplantation.
J. Sowden, C. Cepko, D. Clegg, D. Gamm +8 more
2014Translational Vision Science & Technology5 citations Open access
Semantic Scholar
Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy
M. Kabra, Pawan K. Shahi, Yuyuan Wang, Divya Sinha +13 more
2023bioRxiv3 citations Open access
Semantic Scholar
Necrotizing myositis in a rectus muscle arising in the setting of long-standing Langerhans cell histiocystosis and recent dabrafenib treatment
Suzanne W. van Landingham, D. Puccetti, H. Potter, D. Gamm +2 more
2020American Journal of Ophthalmology Case Reports3 citations Open access
Semantic Scholar

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M. Phillips×17
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E. Capowski×13
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Divya Sinha×8
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Allison L. Ludwig×8
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Kimberly L. Edwards

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Ruchira Singh×7

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B. Pattnaik — researcher profile on SciRah

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D. Zack — researcher profile on SciRah

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Krishanu Saha×6

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Lindsey D. Jager×5

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