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L. Mahimainathan · SciRah

Researcher profile · Semantic Scholar

L. Mahimainathan

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L. Mahimainathan — researcher profile on SciRah

h-index: 26
Works: 56
Citations: 2,764

Most-cited papers

Requirement of BMP-2-induced Phosphatidylinositol 3-Kinase and Akt Serine/Threonine Kinase in Osteoblast Differentiation and Smad-dependent BMP-2 Gene Transcription*
N. Ghosh-choudhury, S. Abboud, R. Nishimura, A. Celeste +2 more
2002Journal of Biological Chemistry309 citations Open access
Semantic Scholar
A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy.
Myung-Ja Lee, D. Féliers, M. M. Mariappan, K. Sataranatarajan +7 more
2007AJP - Renal Physiology292 citations
Semantic Scholar
Interleukin-18-induced Human Coronary Artery Smooth Muscle Cell Migration Is Dependent on NF-κB- and AP-1-mediated Matrix Metalloproteinase-9 Expression and Is Inhibited by Atorvastatin*
B. Chandrasekar, Srinivas Mummidi, L. Mahimainathan, Devang N. Patel +4 more
2006Journal of Biological Chemistry215 citations Open access
Semantic Scholar
Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells
M. Narasimhan, Dhyanesh Patel, D. Vedpathak, M. Rathinam +2 more
2012PLoS ONE195 citations Open access
Semantic Scholar
Mesangial Cell Hypertrophy by High Glucose Is Mediated by Downregulation of the Tumor Suppressor PTEN
L. Mahimainathan, F. Das, B. Venkatesan, G. G. Choudhury
2006Diabetes170 citations
Semantic Scholar
Clinical Evaluation of the Abbott Alinity SARS-CoV-2 Spike-Specific Quantitative IgG and IgM Assays among Infected, Recovered, and Vaccinated Groups
M. Narasimhan, L. Mahimainathan, Ellen Araj, A. E. Clark +16 more
2021medRxiv117 citations Open access
Semantic Scholar
Inactivation of Platelet-derived Growth Factor Receptor by the Tumor Suppressor PTEN Provides a Novel Mechanism of Action of the Phosphatase*
L. Mahimainathan, G. G. Choudhury
2004Journal of Biological Chemistry106 citations Open access
Semantic Scholar
In-Depth Evaluation of a Case of Presumed Myocarditis After the Second Dose of COVID-19 mRNA Vaccine
A. Muthukumar, M. Narasimhan, Quan-Zhen Li, L. Mahimainathan +15 more
2021Circulation103 citations Open access
Semantic Scholar
Hydrogen Peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity
M. Narasimhan, A. Riar, M. Rathinam, D. Vedpathak +2 more
2014Toxicology Letters95 citations Open access
Semantic Scholar
Downregulation of catalase by reactive oxygen species via PI 3 kinase/Akt signaling in mesangial cells
B. Venkatesan, L. Mahimainathan, F. Das, N. Ghosh-choudhury +1 more
2007Journal of Cellular Physiology92 citations
Semantic Scholar
5-HT2C Receptor Knockdown in the Amygdala Inhibits Neuropathic-Pain-Related Plasticity and Behaviors
G. Ji, Wei Zhang, L. Mahimainathan, M. Narasimhan +5 more
2017Journal of Neuroscience86 citations Open access
Semantic Scholar
c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells.
G. G. Choudhury, L. Mahimainathan, F. Das, B. Venkatesan +1 more
2006Cellular Signalling69 citations
Semantic Scholar
Serological Response in Lung Transplant Recipients after Two Doses of SARS-CoV-2 mRNA Vaccines
M. Narasimhan, L. Mahimainathan, A. E. Clark, Amena Usmani +7 more
2021medRxiv68 citations Open access
Semantic Scholar
Akt kinase targets association of CBP with SMAD 3 to regulate TGFβ‐induced expression of plasminogen activator inhibitor‐1
F. Das, N. Ghosh-choudhury, B. Venkatesan, Xiaonan Li +2 more
2008Journal of Cellular Physiology68 citations
Semantic Scholar
Raptor-rictor axis in TGFβ-induced protein synthesis
F. Das, N. Ghosh-choudhury, L. Mahimainathan, B. Venkatesan +4 more
200862 citations
Semantic Scholar
Interleukin-18 induces human cardiac endothelial cell death via a novel signaling pathway involving NF-kappaB-dependent PTEN activation.
B. Chandrasekar, A. J. Valente, G. Freeman, L. Mahimainathan +1 more
2006Biochemical and Biophysical Research Communications - BBRC62 citations
Semantic Scholar
Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
M. Narasimhan, L. Mahimainathan, M. Rathinam, A. Riar +1 more
2011Molecular Pharmacology59 citations Open access
Semantic Scholar
Astrocyte control of fetal cortical neuron glutathione homeostasis: up‐regulation by ethanol
M. Rathinam, L. Watts, A. Stark, L. Mahimainathan +3 more
2006Journal of Neurochemistry59 citations
Semantic Scholar
Unrestrained Mammalian Target of Rapamycin Complexes 1 and 2 Increase Expression of Phosphatase and Tensin Homolog Deleted on Chromosome 10 to Regulate Phosphorylation of Akt Kinase*
F. Das, N. Ghosh-choudhury, Nirmalya Dey, C. Mandal +4 more
2011Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Phosphatidylinositol 3-Kinase Regulates Bone Morphogenetic Protein-2 (BMP-2)-induced Myocyte Enhancer Factor 2A-dependent Transcription of BMP-2 Gene in Cardiomyocyte Precursor Cells*
N. Ghosh-choudhury, S. Abboud, L. Mahimainathan, B. Chandrasekar +1 more
2003Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B
B. Venkatesan, N. Ghosh-choudhury, F. Das, L. Mahimainathan +4 more
2008The FASEB Journal41 citations Open access
Semantic Scholar
Astrocyte Mediated Protection of Fetal Cerebral Cortical Neurons from Rotenone and Paraquat
M. Rathinam, L. Watts, M. Narasimhan, A. Riar +2 more
2012Environmental Toxicology and Pharmacology36 citations Open access
Semantic Scholar
Tuberin regulates the DNA repair enzyme OGG1.
S. L. Habib, D. Riley, L. Mahimainathan, B. Bhandari +2 more
2008AJP - Renal Physiology36 citations
Semantic Scholar
Raptor-rictor axis in TGFbeta-induced protein synthesis.
F. Das, N. Ghosh-choudhury, L. Mahimainathan, B. Venkatesan +4 more
2008Cellular Signalling35 citations
Semantic Scholar
TSC2 Deficiency Increases PTEN via HIF1α*
L. Mahimainathan, N. Ghosh-choudhury, B. Venkatesan, F. Das +6 more
2009Journal of Biological Chemistry29 citations Open access
Semantic Scholar
EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK-dependent and AKT kinase-independent manner: involvement of c-fos and p27Kip1.
L. Mahimainathan, N. Ghosh-choudhury, B. Venkatesan, R. Danda +1 more
2005AJP - Renal Physiology28 citations
Semantic Scholar
Saliva for use with a point of care assay for the rapid diagnosis of COVID-19
J. SoRelle, L. Mahimainathan, Clare McCormick-Baw, D. Cavuoti +5 more
2020Clinica chimica acta; international journal of clinical chemistry26 citations Open access
Semantic Scholar
PI 3 kinase-dependent Akt kinase and PKCε independently regulate interferon-γ-induced STAT1α serine phosphorylation to induce monocyte chemotactic protein-1 expression
B. Venkatesan, L. Mahimainathan, N. Ghosh-choudhury, Y. Gorin +4 more
200626 citations
Semantic Scholar
Regulation of PI 3-K, PTEN, p53, and mTOR in Malignant and Benign Tumors Deficient in Tuberin.
S. L. Habib, Anamika Yadav, L. Mahimainathan, A. J. Valente
2011Genes & cancer20 citations Open access
Semantic Scholar
Ethanol-Induced Transcriptional Activation of Programmed Cell Death 4 (Pdcd4) Is Mediated by GSK-3β Signaling in Rat Cortical Neuroblasts
A. Riar, M. Narasimhan, M. Rathinam, D. Vedpathak +3 more
2014PLoS ONE19 citations Open access
Semantic Scholar
Programmed Cell Death 4 (PDCD4): A Novel Player in Ethanol Mediated Suppression of Protein Translation in Primary Cortical Neurons and Developing Cerebral Cortex
M. Narasimhan, M. Rathinam, A. Riar, Dhyanesh Patel +5 more
2012Alcoholism: Clinical and Experimental Research18 citations Open access
Semantic Scholar
Astrocytes Prevent Ethanol Induced Apoptosis of Nrf2 Depleted Neurons by Maintaining GSH Homeostasis
M. Narasimhan, M. Rathinam, Dhyanesh Patel, G. Henderson +1 more
2012Open Journal of Apoptosis17 citations Open access
Semantic Scholar
Ethanol Impairs NRF2/Antioxidant and Growth Signaling in the Intact Placenta In Vivo and in Human Trophoblasts
Sambantham Shanmugam, Dhyanesh Patel, John M. Wolpert, Caezaan Keshvani +6 more
2019Biomolecules16 citations Open access
Semantic Scholar
Ethanol induces cytostasis of cortical basal progenitors
A. Riar, M. Narasimhan, M. Rathinam, G. Henderson +1 more
2016Journal of Biomedical Sciences15 citations Open access
Semantic Scholar
Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt.
M. Quinones, Yogeshwar V. Kalkonde, C. Estrada, F. Jimenez +13 more
2008Molecular and cellular neurosciences12 citations
Semantic Scholar
PI 3 kinase-dependent Akt kinase and PKCepsilon independently regulate interferon-gamma-induced STAT1alpha serine phosphorylation to induce monocyte chemotactic protein-1 expression.
B. Venkatesan, L. Mahimainathan, N. Ghosh-choudhury, Y. Gorin +4 more
2006Cellular Signalling12 citations
Semantic Scholar
Diagnostic Performance of a Rapid Point‐of‐care Test for SARS‐CoV‐2 in an Urban Emergency Department Setting
S. McDonald, D. Courtney, A. E. Clark, A. Muthukumar +7 more
2020Academic Emergency Medicine10 citations Open access
Semantic Scholar
Role for Cystathionine γ Lyase (CSE) in an Ethanol (E)-Induced Lesion in Fetal Brain GSH Homeostasis
Dhyanesh Patel, M. Rathinam, C. Jarvis, L. Mahimainathan +2 more
2018International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
TGFβ intercepts nuclear glycogen synthase kinase 3β to inhibit PDGF‐induced DNA synthesis in mesangial cells
F. Das, L. Mahimainathan, N. Ghosh-choudhury, B. Venkatesan +3 more
20078 citations
Semantic Scholar
SARS-CoV-2 coinfections with variant genomic lineages identified by multiplex fragment analysis
Richard Lueking, A. E. Clark, M. Narasimhan, L. Mahimainathan +3 more
2022Frontiers in Genetics7 citations Open access
Semantic Scholar
Ethanol (E) Impairs Fetal Brain GSH Homeostasis by Inhibiting Excitatory Amino-Acid Carrier 1 (EAAC1)-Mediated Cysteine Transport
Dhyanesh Patel, L. Mahimainathan, M. Narasimhan, M. Rathinam +1 more
2017International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
GPR18-NAGly system in periaqueductal gray and chronic neuropathic pain.
M. Narasimhan, L. Mahimainathan, P. Reddy, K. Benamar
2020Biochimica et Biophysica Acta - Molecular Basis of Disease5 citations Open access
Semantic Scholar
TGFbeta intercepts nuclear glycogen synthase kinase 3beta to inhibit PDGF-induced DNA synthesis in mesangial cells.
F. Das, L. Mahimainathan, N. Ghosh-choudhury, B. Venkatesan +3 more
2007FEBS Letters5 citations
Semantic Scholar
Silent SARS-CoV-2 Infections, Waning Immunity, Serology Testing, and COVID-19 Vaccination: A Perspective
M. Narasimhan, L. Mahimainathan, J. Noh, A. Muthukumar
2021Frontiers in Immunology3 citations Open access
Semantic Scholar
Overexpression of Nrf 2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic
M. Narasimhan, L. Mahimainathan, M. Rathinam, A. Riar +1 more
20113 citations
Semantic Scholar
Ethanol inhibition of undifferentiated rat neural progenitor cell replication can be prevented by chlorogenic acid via the NFATc4/CSE signalling pathway.
Sambantham Shanmugam, Dhyanesh Patel, A. L. Rodríguez, Aashlesha Walchale +5 more
2023Alcohol2 citations
Semantic Scholar
‘nAb’ the self-reactive activity in the COVID-19 combat
M. Narasimhan, L. Mahimainathan, A. Muthukumar
2021Signal Transduction and Targeted Therapy2 citations Open access
Semantic Scholar
Evaluation of SARS-CoV-2 Serological Testing in Patients with Multiple Myeloma and Other Hematologic Malignancies on Monoclonal Antibody Therapies
L. Mahimainathan, M. Narasimhan, R. Corchado, Hetalkumari Patel +4 more
2020Diagnostics2 citations Open access
Semantic Scholar
Expanding COVID-19 Vaccine Availability: Role for Combined Orthogonal Serology Testing (COST)
M. Narasimhan, L. Mahimainathan, Ellen Araj, A. E. Clark +8 more
2021Vaccines1 citations Open access
Semantic Scholar
Variable Creatinine Levels in Critical Care Patients: A Concerning Knowledge Gap
T. Shah, M. Narasimhan, M. Rathinam, Karen Relle +6 more
2021Journal of Clinical Medicine1 citations Open access
Semantic Scholar

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G. G. Choudhury×18
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N. Ghosh-choudhury×15
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