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T. Wehler · SciRah

Researcher profile · Semantic Scholar

T. Wehler

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T. Wehler — researcher profile on SciRah

h-index: 30
Works: 110
Citations: 2,768

Most-cited papers

Efficacy of the Irreversible ErbB Family Blocker Afatinib in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)–Pretreated Non–Small-Cell Lung Cancer Patients with Brain Metastases or Leptomeningeal Disease
P. Hoffknecht, Amanda Tufman, T. Wehler, T. Pelzer +7 more
2014Journal of Thoracic Oncology248 citations Open access
Semantic Scholar
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
A. Papachristofilou, M. Hipp, U. Klinkhardt, M. Früh +23 more
2019Journal of Immunotherapy for Cancer199 citations Open access
Semantic Scholar
Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4
C. Schimanski, R. Bahre, I. Gockel, A. Müller +11 more
2006British Journal of Cancer178 citations Open access
Semantic Scholar
Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive®) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer
M. Sebastian, A. Papachristofilou, C. Weiss, M. Früh +11 more
2014BMC Cancer119 citations Open access
Semantic Scholar
A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
S. Ramalingam, G. Goss, R. Rosell, G. Schmid-Bindert +18 more
2015Annals of Oncology103 citations Open access
Semantic Scholar
Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines.
T. Wehler, Marion Nonn, Britta Brandt, C. Britten +8 more
2007Blood102 citations
Semantic Scholar
Rapid identification and sorting of viable virus-reactive CD4(+) and CD8(+) T cells based on antigen-triggered CD137 expression.
T. Wehler, Michael Karg, E. Distler, A. Konur +5 more
2008JIM - Journal of Immunological Methods99 citations
Semantic Scholar
Prophylactic transfer of CD8-depleted donor lymphocytes after T-cell-depleted reduced-intensity transplantation.
R. Meyer, C. Britten, D. Wehler, K. Bender +10 more
2007Blood87 citations Open access
Semantic Scholar
Long-term outcomes in radically treated synchronous vs. metachronous oligometastatic non-small-cell lung cancer
J. Fleckenstein, Alev Petroff, H. Schäfers, T. Wehler +2 more
2016BMC Cancer83 citations Open access
Semantic Scholar
KRAS G12C-mutated advanced non-small cell lung cancer: A real-world cohort from the German prospective, observational, nation-wide CRISP Registry (AIO-TRK-0315).
M. Sebastian, W. Eberhardt, P. Hoffknecht, M. Metzenmacher +20 more
2021Lung Cancer80 citations Open access
Semantic Scholar
Quality of Life in NSCLC Survivors — A Multicenter Cross‐Sectional Study
M. Hechtner, M. Eichler, B. Wehler, R. Buhl +13 more
2019Journal of Thoracic Oncology79 citations Open access
Semantic Scholar
High incidence of cataract formation after implantation of a silicone posterior chamber lens in phakic, highly myopic eyes.
P. Brauweiler, T. Wehler, M. Busin
1999Ophthalmology (Rochester, Minn.)74 citations
Semantic Scholar
Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease.
T. Wehler, F. Wolfert, C. Schimanski, I. Gockel +8 more
2006Oncology Report73 citations Open access
Semantic Scholar
Prevalence of PD-L1 expression in patients with non-small cell lung cancer screened for enrollment in KEYNOTE-001, -010, and -024
C. Aggarwal, D. Abreu, E. Felip, E. Carcereny +9 more
201671 citations Open access
Semantic Scholar
Safety and Patient-Reported Outcomes of Atezolizumab Plus Chemotherapy With or Without Bevacizumab Versus Bevacizumab Plus Chemotherapy in Non–Small-Cell Lung Cancer
M. Reck, T. Wehler, F. Orlandi, N. Nogami +15 more
2020Journal of Clinical Oncology66 citations Open access
Semantic Scholar
Preclinical analyses and phase I evaluation of LY2603618 administered in combination with Pemetrexed and cisplatin in patients with advanced cancer
E. Calvo, Victor J. Chen, M. Marshall, U. Ohnmacht +14 more
2014Investigational new drugs63 citations
Semantic Scholar
A randomized, phase 2 evaluation of the CHK1 inhibitor, LY2603618, administered in combination with pemetrexed and cisplatin in patients with advanced nonsquamous non-small cell lung cancer.
T. Wehler, Michael Thomas, C. Schumann, J. Bosch-Barrera +12 more
2017Lung Cancer51 citations
Semantic Scholar
Strong Expression of Chemokine Receptor CXCR4 by Renal Cell Carcinoma Correlates with Advanced Disease
T. Wehler, C. Graf, S. Biesterfeld, W. Brenner +7 more
2008Journal of Oncology43 citations Open access
Semantic Scholar
Chemokine receptor CCR7 enhances intrahepatic and lymphatic dissemination of human hepatocellular cancer.
C. Schimanski, R. Bahre, I. Gockel, T. Junginger +6 more
2006Oncology Report40 citations Open access
Semantic Scholar
Psychological distress in lung cancer survivors at least 1 year after diagnosis—Results of a German multicenter cross‐sectional study
M. Eichler, M. Hechtner, B. Wehler, R. Buhl +11 more
2018Psycho-Oncology38 citations
Semantic Scholar
Liver transplanted patients with preoperative autoimmune hepatitis and immunological disorders are at increased risk for Post-Transplant Lymphoproliferative Disease (PTLD).
T. Zimmermann, M. Hoppe-Lotichius, Vuk Tripkovic, A. Barreiros +8 more
2010European journal of internal medicine36 citations
Semantic Scholar
Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma--a rationale for a molecular targeting strategy?
D. Drescher, M. Moehler, I. Gockel, K. Frerichs +13 more
2007World Journal of Gastroenterology35 citations Open access
Semantic Scholar
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy.
T. Wehler, K. Frerichs, C. Graf, D. Drescher +9 more
2008Oncology Report34 citations
Semantic Scholar
PDGFRα/β expression correlates with the metastatic behavior of human colorectal cancer: A possible rationale for a molecular targeting strategy
T. Wehler, K. Frerichs, C. Graf, D. Drescher +9 more
200833 citations Open access
Semantic Scholar
Randomised phase II trial of trofosfamide vs. doxorubicin in elderly patients with untreated metastatic soft-tissue sarcoma.
J. Hartmann, H. Kopp, V. Gruenwald, S. Piperno-Neumann +14 more
2019European Journal of Cancer31 citations
Semantic Scholar
Isolation and characterization of a trisulfide variant of recombinant human growth hormone formed during expression in Escherichia coli.
Claes Andersson, P. Edlund, P. Gellerfors, Yngve Hansson +10 more
2009International journal of peptide & protein research30 citations
Semantic Scholar
Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft—no benefit of combination therapy
T. Wehler, S. Hamdi, A. Maderer, C. Graf +8 more
2012International Journal of Colorectal Disease28 citations Open access
Semantic Scholar
Acute myeloid leukemia (AML)-reactive cytotoxic T lymphocyte clones rapidly expanded from CD8(+) CD62L((high)+) T cells of healthy donors prevent AML engraftment in NOD/SCID IL2Rgamma(null) mice.
E. Distler, C. Wölfel, Sylvia Köhler, Marion Nonn +8 more
2008Experimental Hematology26 citations Open access
Semantic Scholar
Nintedanib plus docetaxel after progression on first-line immunochemotherapy in patients with lung adenocarcinoma: Cohort C of the non-interventional study, VARGADO
C. Grohé, T. Wehler, T. Dechow, S. Henschke +8 more
2021Translational Lung Cancer Research25 citations Open access
Semantic Scholar
Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells.
S. Kausche, T. Wehler, E. Schnürer, V. Lennerz +10 more
2006Cancer Research19 citations
Semantic Scholar
Real-World Efficacy of Nintedanib Plus Docetaxel After Progression on Immune Checkpoint Inhibitors: Results From the Ongoing, Non-interventional VARGADO Study.
C. Grohé, W. Blau, W. Gleiber, S. Haas +7 more
2022Clinics in oncology18 citations Open access
Semantic Scholar
Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.
M. Kahraman, Thomas Laufer, C. Backes, Hannah Schrörs +7 more
2017Clinical Chemistry18 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
International Tailored Chemotherapy Adjuvant (ITACA) Trial, a Phase III Multicenter Randomized Trial Comparing Adjuvant Pharmacogenomic-Driven Chemotherapy versus Standard Adjuvant Chemotherapy in completely Resected Stage II-IIIA Non-Small Cell Lung Cancer.
S. Novello, V. Torri, C. Grohé, S. Kurz +32 more
2021Annals of Oncology17 citations Open access
Semantic Scholar
Erratum to: Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective
T. Wehler, C. Graf, M. Möhler, J. Herzog +6 more
2013Journal of Cancer Research and Clinical Oncology15 citations Open access
Semantic Scholar
Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease
Michael Weber, Corinna Lupp, Pamela Stein, A. Kreft +5 more
2013PLoS ONE15 citations Open access
Semantic Scholar
HDAC inhibitor-loaded bone cement for advanced local treatment of osteosarcoma and chondrosarcoma.
M. Tonak, M. Becker, C. Graf, L. Eckhard +4 more
2014Anticancer Research14 citations
Semantic Scholar
Patient-reported outcomes (PROs) in the randomized, phase III IMpower150 study of atezolizumab (atezo) + chemotherapy (chemo) ± bevacizumab (bev) vs chemo + bev in 1L nonsquamous metastatic NSCLC (mNSCLC).
M. Reck, T. Karagiannis, T. Wehler, M. Shtivelband +7 more
201813 citations
Semantic Scholar
A Randomized Phase II Trial Comparing the Efficacy and Safety of Pioglitazone, Clarithromycin and Metronomic Low-Dose Chemotherapy with Single-Agent Nivolumab Therapy in Patients with Advanced Non-small Cell Lung Cancer Treated in Second or Further Line (ModuLung)
D. Heudobler, C. Schulz, J. Fischer, P. Staib +14 more
2021Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Use of psychosocial services by lung cancer survivors in Germany
M. Eichler, M. Hechtner, B. Wehler, R. Buhl +9 more
2019Strahlentherapie und Onkologie (Print)12 citations
Semantic Scholar
Analysis of the expression of SDF-1 splicing variants in human colorectal cancer and normal mucosa tissues.
R. Allami, C. Graf, K. Martchenko, B. Voss +6 more
2016Oncology Letters12 citations Open access
Semantic Scholar
Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes.
J. Chromik, E. Schnürer, Ralf Georg Meyer, T. Wehler +4 more
2006JIM - Journal of Immunological Methods12 citations
Semantic Scholar
Phase 3, randomized, placebo-controlled study of stereotactic body radiotherapy (SBRT) with or without pembrolizumab in patients with unresected stage I or II non–small cell lung cancer (NSCLC): KEYNOTE-867.
S. Jabbour, B. Houghton, A. Robinson, X. Quantin +10 more
2022Journal of Clinical Oncology11 citations
Semantic Scholar
Cylindromatosis (Cyld) gene mutation in T cells promotes the development of an IL-9-dependent allergic phenotype in experimental asthma.
S. Reuter, J. Maxeiner, H. Meyer-Martin, Anastasija Michel +9 more
2016Cellular Immunology11 citations
Semantic Scholar
Xenograft models for undifferentiated pleomorphic sarcoma not otherwise specified are essential for preclinical testing of therapeutic agents.
M. Becker, C. Graf, M. Tonak, M. Radsak +7 more
2016Oncology Letters11 citations Open access
Semantic Scholar
Last line therapy with sorafenib in colorectal cancer: A retrospective analysis.
K. Martchenko, I. Schmidtmann, T. Thomaidis, Verena Thole +5 more
2016World Journal of Gastroenterology11 citations Open access
Semantic Scholar
Structure-Based Discovery of Small Molecules Binding to RNA
T. Wehler, R. Brenk
20179 citations
Semantic Scholar
Combination therapies with oxaliplatin and oral capecitabine or intravenous 5-FU show similar toxicity profiles in gastrointestinal carcinoma patients if hand-food syndrome prophylaxis is performed continuously.
T. Wehler, Yang Cao, P. Galle, M. Theobald +2 more
2012Oncology Letters9 citations Open access
Semantic Scholar
1286P Activity of tepotinib in brain metastases (BM): Preclinical models and clinical data from patients (pts) with MET exon 14 (METex14) skipping NSCLC
S. Viteri, J. Mazières, R. Veillon, E. Felip +14 more
20208 citations Open access
Semantic Scholar
Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective
T. Wehler, C. Graf, M. Möhler, J. Herzog +6 more
2013Journal of Cancer Research and Clinical Oncology8 citations Open access
Semantic Scholar

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