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N. Monks · SciRah

Researcher profile · Semantic Scholar

N. Monks

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N. Monks — researcher profile on SciRah

h-index: 19
Works: 54
Citations: 1,096

Most-cited papers

Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells
N. Monks, Shuqian Liu, Yongsheng Xu, Hui-ying Yu +2 more
2007Molecular Cancer Therapeutics162 citations
Semantic Scholar
Anticancer, antichemotactic and antimicrobial activities of marine sponges collected off the coast of Santa Catarina, southern Brazil
N. Monks, C. Lerner, A. Henriques, Fabiane M. Farias +5 more
200293 citations
Semantic Scholar
Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
Matthew J. Sale, Emma Minihane, N. Monks, Rebecca Gilley +14 more
2019Nature Communications70 citations Open access
Semantic Scholar
Comparative RNA-Seq and Microarray Analysis of Gene Expression Changes in B-Cell Lymphomas of Canis familiaris
Marie R. Mooney, J. Bond, N. Monks, Emily Eugster +11 more
2013PLoS ONE70 citations Open access
Semantic Scholar
Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue
D. Monsma, N. Monks, David M. Cherba, D. Dylewski +12 more
2012Journal of Translational Medicine65 citations Open access
Semantic Scholar
Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy.
N. Durham, K. Mulgrew, K. McGlinchey, N. Monks +5 more
2017Molecular Therapy64 citations Open access
Semantic Scholar
Blocking anti‐apoptosis as a strategy for cancer chemotherapy: NF‐κB as a target
N. Monks, D. Biswas, A. Pardee
200458 citations
Semantic Scholar
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305.
Krista Kinneer, Philipp Wortmann, Z. Cooper, Niall J Dickinson +28 more
2022Clinical Cancer Research57 citations Open access
Semantic Scholar
Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer
Cho Song, F. Zammarchi, David G. Williams, C. Havenith +30 more
2018Molecular Cancer Therapeutics38 citations Open access
Semantic Scholar
Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.
D. Monsma, David M. Cherba, Emily Eugster, D. Dylewski +10 more
2015American Journal of Cancer Research38 citations
Semantic Scholar
Anti-tumour Screening of Brazilian Plants
N. Monks, S. Bordignon, A. Ferraz, Katia R. Machado +7 more
200238 citations Open access
Semantic Scholar
Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-kappaB as a target.
N. Monks, D. Biswas, A. Pardee
2004Journal of Cellular Biochemistry32 citations
Semantic Scholar
Anoikis-resistant subpopulations of human osteosarcoma display significant chemoresistance and are sensitive to targeted epigenetic therapies predicted by expression profiling
J. Foley, Donald J. Scholten Ii, N. Monks, David M. Cherba +6 more
2015Journal of Translational Medicine28 citations Open access
Semantic Scholar
Melanoma genotypes and phenotypes get personal
J. Pimiento, E. M. Larkin, K. Smalley, G. Wiersma +4 more
2013Laboratory Investigation27 citations
Semantic Scholar
In vitro Cytotoxicity of Extracts from Brazilian Asteraceae
N. Monks, A. Ferraz, S. Bordignon, Katia R. Machado +3 more
200227 citations Open access
Semantic Scholar
Using a rhabdomyosarcoma patient‐derived xenograft to examine precision medicine approaches and model acquired resistance
David J. Monsma, David M. Cherba, Patrick J. Richardson, S. Vance +12 more
2014Pediatric Blood & Cancer23 citations
Semantic Scholar
Sensitivity of breast cancer cell lines to recombinant thiaminase I
Shuqian Liu, N. Monks, J. Hanes, T. Begley +2 more
2009Cancer Chemotherapy and Pharmacology23 citations Open access
Semantic Scholar
DNA interstrand cross-linking and TP53 status as determinants of tumour cell sensitivity in vitro to the antibody-directed enzyme prodrug therapy ZD2767.
N. Monks, D. Blakey, S. East, R. Dowell +4 more
2002European Journal of Cancer20 citations Open access
Semantic Scholar
Targeting the NF‐κB pathway in estrogen receptor negative MDA‐MB‐231 breast cancer cells using small inhibitory RNAs
N. Monks, A. Pardee
2006Journal of Cellular Biochemistry19 citations
Semantic Scholar
Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition.
Abigail Daily, N. Monks, M. Leggas, J. Moscow
2010Toxicon17 citations
Semantic Scholar
A multi-site feasibility study for personalized medicine in canines with Osteosarcoma
N. Monks, David M. Cherba, S. Kamerling, H. Simpson +9 more
2013Journal of Translational Medicine16 citations Open access
Semantic Scholar
Molecular-guided therapy predictions reveal drug resistance phenotypes and treatment alternatives in malignant peripheral nerve sheath tumors
Jacqueline D. Peacock, David M. Cherba, Kevin Kampfschulte, Mallory K Smith +3 more
2013Journal of Translational Medicine15 citations Open access
Semantic Scholar
Natural Products Genomics: A novel approach for the discovery of anti-cancer therapeutics.
N. Monks, B. Li, S. Gunjan, D. Rogers +3 more
2011Journal of pharmacological and toxicological methods14 citations
Semantic Scholar
Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue
N. Monks, D. Blakey, N. Curtin, S. East +2 more
2001British Journal of Cancer13 citations Open access
Semantic Scholar
Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy.
Maria Letizia Giardino Torchia, M. Letizia, Ryan Gilbreth, Ashley A. Merlino +15 more
2022Cytotherapy12 citations Open access
Semantic Scholar
Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12
C. Kurokawa, Sonia Agrawal, Abhisek Mitra, Elena Galvani +18 more
2024Molecular therapy. Oncology8 citations Open access
Semantic Scholar
Discovery and Development of MEDI7247, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate Targeting ASCT2, for Treating Hematological Cancers
N. Pore, Kevin P. Schifferli, N. Monks, R. Tammali +10 more
2018Blood8 citations
Semantic Scholar
Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia
I. Kinjyo, K. Matlawska-Wasowska, Xiao-Ru Chen, N. Monks +3 more
2017Pediatric Blood & Cancer6 citations Open access
Semantic Scholar
Metabolism and transport pathways of the blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10-hydroxycamptothecin).
M. Milewska, Jamie Horn, N. Monks, J. Moscow +2 more
2009Journal of Clinical Oncology6 citations
Semantic Scholar
Abstract LB-298: MEDI7247: A first in class antibody drug conjugate targeting ASCT2 in a range of solid tumors
Kevin P. Schifferli, N. Monks, R. Tammali, M. Jack Borrok +6 more
2018Immunology5 citations
Semantic Scholar
Abstract LB-295: MEDI7247, a novel pyrrolobenzodiazepine ADC targeting ASCT2 with potentin vivoactivity across a spectrum of hematological malignancies
N. Monks, Kevin P. Schifferli, R. Tammali, M. Jack Borrok +4 more
2018Immunology5 citations
Semantic Scholar
Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT)
N. Monks, J. A. Calvete, N. Curtin, D. Blakey +2 more
2000British Journal of Cancer5 citations Open access
Semantic Scholar
Addressing the design of in vitro models for the investigation of microcystins: The essential role of transporter‐mediated uptake
N. Monks, J. Moscow
2010Cell Biology International4 citations
Semantic Scholar
Abstract 76: Synthetic lethal targeting ofBRCAmutant tumors with antibody linked pyrrolobenzodiazepine dimers
H. Zhong, R. Tammali, Cui Chen, Christine Fazenbaker +5 more
20173 citations
Semantic Scholar
Abstract LB-296: Discovery and development of MEDI7247, a novel Pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2, for treating hematological and solid cancers
N. Pore, M. Borrok, Marlon C. Rebellato, M. Hinrichs +6 more
2018Immunology2 citations
Semantic Scholar
Microcystins as Agents for Treatment of Cancer
N. Monks
20172 citations
Semantic Scholar
I06 Allele-selective inhibition of mutant htt transcription throughout the brain after subcutaneous administration of a patrol™-enabled investigational genetic therapy in the r6/2 Huntington’s disease transgenic mouse model
R. Friedlander, V. Di Caro, D. Carlisle, N. Monks +16 more
2022Infotech@Aerospace Conference1 citations
Semantic Scholar
Abstract 5544: Newcastle Disease Virus in human derived tumors: Understanding immune recruitment and activation via virally delivered IL-12
N. Durham, K. McGlinchey, S. Burke, T. Creasy +11 more
2020Immunology1 citations
Semantic Scholar
Abstract A004: MEDI3726 (ADCT-401), a novel antibody-drug conjugate targeting PSMA, has potent in vivo antitumor activity in prostate cancer patient-derived xenograft models
Cho Song, F. Zammarchi, N. Monks, Kapil Vashisht +17 more
2018Poster Presentations - Proffered Abstracts1 citations
Semantic Scholar
Molecular-guided therapy predictions reveal drug resistance phenotypes and treatment alternatives in malignant peripheral nerve sheath tumors
Jacqueline D. Peacock, David M. Cherba, Kevin Kampfschulte, Mallory K Smith +3 more
2013Journal of Translational Medicine1 citations Open access
Semantic Scholar
Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue
D. Monsma, N. Monks, David M. Cherba, D. Dylewski +12 more
2012Journal of Translational Medicine1 citations Open access
Semantic Scholar
Screening in vitro do efeito anticâncer de espécies de Asteraceae
R. Lopes, N. Monks, Katia R. Machado, Alexandre de Barros Falcão Ferraz +4 more
20011 citations
Semantic Scholar
Abstract 1765: Discovery and first disclosure of AZD8205, a B7-H4-targeted antibody-drug conjugate utilizing a novel topoisomerase I linker-warhead
Krista Kinneer, Niall J Dickinson, Luke A. Masterson, Thais Cailleau +32 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 1813: The genetic makeup of patient-derived xenografts shapes the immune landscape of humanized mice tumors
Maneesh Singh, Laura Bradshaw, Laura B Prickett, G. Matthew +6 more
2021Immunology0 citations
Semantic Scholar
112 Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy
Letizia Giardino, Ryan Gilbreth, Cui Chen, Erin Sult +12 more
20200 citations Open access
Semantic Scholar
Abstract 821: B7-H3 is a potential antibody drug conjugate target for the treatment of prostate cancer
G. Davies, Kelli Ryan, Alison J. Smith, Chris Lloyd +4 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract A37: Complex crosstalk between MAPK signaling and energy metabolism in melanoma
N. Lanning, P. Jose, N. Monks, Paula J. Davidson +7 more
20140 citations
Semantic Scholar
Abstract A70: Chemotherapy-resistant subpopulations in a tumor-initiating cell model of human osteosarcoma
J. Foley, N. Monks, D. Scholten, D. Monsma +3 more
20140 citations
Semantic Scholar
Abstract B12: Overcoming acquired resistance to vemurafenib using clinically relevant PDX models of melanoma.
N. Monks, D. Monsma, David M. Cherba, Emily Eugster +14 more
20130 citations
Semantic Scholar
Abstract 363: Development of computer-aided detection (CAD) tool for liver metastasis micro CT imaging using targeted contrast agent
Anderson Peck, Jeff VanOss, D. Monsma, N. Monks +5 more
20120 citations
Semantic Scholar

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R. Tammali×12
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C. Webb×10
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Kevin P. Schifferli×9
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Kevin P. Schifferli — researcher profile on SciRah
David M. Cherba×9
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D. Monsma — researcher profile on SciRah

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Emily Eugster×7

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Emily Eugster — researcher profile on SciRah

B. Nickoloff×6

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