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U. Syrbe · SciRah

Researcher profile · Semantic Scholar

U. Syrbe

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U. Syrbe — researcher profile on SciRah

h-index: 24
Works: 61
Citations: 4,570

Most-cited papers

Monocyte deactivation in septic patients: Restoration by IFN-γ treatment
W. Döcke, F. Randow, U. Syrbe, D. Krausch +4 more
1997Nature Medicine831 citations
Semantic Scholar
Monocyte deactivation in septic patients: restoration by IFN-gamma treatment.
W. Döcke, F. Randow, U. Syrbe, D. Krausch +4 more
1997Nature Medicine555 citations
Semantic Scholar
Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta
F. Randow, U. Syrbe, C. Meisel, D. Krausch +3 more
1995Journal of Experimental Medicine487 citations Open access
Semantic Scholar
TNF signaling drives myeloid-derived suppressor cell accumulation.
Xue-Qiang Zhao, Lijie Rong, Xiao-Pu Zhao, Xiao Li +9 more
2012Journal of Clinical Investigation355 citations Open access
Semantic Scholar
Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo.
K. Siegmund, M. Feuerer, C. Siewert, Saeed Ghani +9 more
2005Blood289 citations Open access
Semantic Scholar
Cytomegalovirus reactivation and tumour necrosis factor.
W. Döcke, E. Fietze, U. Syrbe, R. von Baehr +6 more
1994The Lancet274 citations
Semantic Scholar
Effect of continuous versus on-demand treatment of ankylosing spondylitis with diclofenac over 2 years on radiographic progression of the spine: results from a randomised multicentre trial (ENRADAS)
J. Sieper, J. Listing, D. Poddubnyy, I. Song +5 more
2015Annals of the Rheumatic Diseases202 citations Open access
Semantic Scholar
Enhanced Antitumor Immunity in Mice Deficient in CD69
E. Esplugues, D. Sancho, J. Vega-Ramos, C. Martínez-A +5 more
2003Journal of Experimental Medicine191 citations Open access
Semantic Scholar
Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.
P. Durek, K. Nordström, G. Gasparoni, A. Salhab +54 more
2016Immunity188 citations Open access
Semantic Scholar
Th1/Th2 subsets: distinct differences in homing and chemokine receptor expression?
U. Syrbe, J. Siveke, A. Hamann
2004Springer Seminars in Immunopathology157 citations
Semantic Scholar
In situ analysis of interleukin-23- and interleukin-12-positive cells in the spine of patients with ankylosing spondylitis.
H. Appel, R. Maier, J. Bleil, A. Hempfing +4 more
2013Arthritis & Rheumatism138 citations
Semantic Scholar
Elevated serum level of the vascular endothelial growth factor predicts radiographic spinal progression in patients with axial spondyloarthritis
D. Poddubnyy, K. Conrad, H. Haibel, U. Syrbe +4 more
2013Annals of the Rheumatic Diseases82 citations
Semantic Scholar
Serum Adipokine Levels in Patients With Ankylosing Spondylitis and Their Relationship to Clinical Parameters and Radiographic Spinal Progression
U. Syrbe, J. Callhoff, K. Conrad, D. Poddubnyy +6 more
2015Arthritis & Rheumatology80 citations
Semantic Scholar
Histomorphologic and Histomorphometric Characteristics of Zygapophyseal Joint Remodeling in Ankylosing Spondylitis
J. Bleil, R. Maier, A. Hempfing, Uwe Schlichting +3 more
2014Arthritis & Rheumatology63 citations Open access
Semantic Scholar
Differential regulation of P-selectin ligand expression in naive versus memory CD4+ T cells: evidence for epigenetic regulation of involved glycosyltransferase genes.
U. Syrbe, S. Jennrich, A. Schottelius, A. Richter +2 more
2004Blood59 citations
Semantic Scholar
Serum levels of leptin and high molecular weight adiponectin are inversely associated with radiographic spinal progression in patients with ankylosing spondylitis: results from the ENRADAS trial
Agnes Hartl, J. Sieper, U. Syrbe, J. Listing +3 more
2017Arthritis Research & Therapy57 citations Open access
Semantic Scholar
Synovial and Peripheral Blood CD4+FoxP3+ T Cells in Spondyloarthritis
H. Appel, Pei-Hua Wu, R. Scheer, C. Kedor +5 more
2011Journal of Rheumatology56 citations Open access
Semantic Scholar
Improvement of Monocyte Function — A New Therapeutic Approach?
W. Döcke, U. Syrbe, A. Meinecke, C. Platzer +8 more
199452 citations
Semantic Scholar
Granulation Tissue Eroding the Subchondral Bone Also Promotes New Bone Formation in Ankylosing Spondylitis
J. Bleil, R. Maier, A. Hempfing, J. Sieper +2 more
2016Arthritis & Rheumatology49 citations Open access
Semantic Scholar
T cells as pioneers: antigen‐specific T cells condition inflamed sites for high‐rate antigen‐non‐specific effector cell recruitment
Saeed Ghani, M. Feuerer, C. Doebis, Uta Lauer +4 more
2009Immunology44 citations Open access
Semantic Scholar
In vivo pre-activation of monocytes in patients with axial spondyloarthritis
K. Conrad, Pei-Hua Wu, J. Sieper, U. Syrbe
2015Arthritis Research & Therapy40 citations Open access
Semantic Scholar
Expression of selectin ligands on murine effector and IL‐10‐producing CD4+ T cells from non‐infected and infected tissues
U. Kretschmer, K. Bonhagen, G. Debes, H. Mittrücker +6 more
2004European Journal of Immunology40 citations Open access
Semantic Scholar
Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS
J. Bleil, J. Sieper, R. Maier, Uwe Schlichting +3 more
2015Arthritis Research & Therapy35 citations Open access
Semantic Scholar
Impaired Peripheral Th1 CD4+ T Cell Response to Escherichia coli Proteins in Patients with Crohn’s Disease and Ankylosing Spondylitis
Asgar Ergin, U. Syrbe, R. Scheer, A. Thiel +5 more
2011Journal of Clinical Immunology26 citations
Semantic Scholar
Synovial cell production of IL-26 induces bone mineralization in spondyloarthritis
L. Heftdal, T. Andersen, Ditte Jæhger, A. Woetmann +7 more
2017Journal of molecular medicine24 citations
Semantic Scholar
Differential synovial Th1 cell reactivity towards Escherichia coli antigens in patients with ankylosing spondylitis and rheumatoid arthritis
U. Syrbe, R. Scheer, Pei-Hua Wu, J. Sieper
2012Annals of the Rheumatic Diseases24 citations
Semantic Scholar
Effects of the Angiotensin II Type 1 Receptor Antagonist Telmisartan on Monocyte Adhesion and Activation in Patients with Essential Hypertension
U. Syrbe, Anja Moebes, J. Scholze, A. Swidsinski +1 more
2007Hypertension Research24 citations Open access
Semantic Scholar
Immunopathology and Infectious Diseases Cellular Players and Role of Selectin Ligands in Leukocyte Recruitment in a T-Cell-Initiated Delayed-Type Hypersensitivity Reaction
C. Doebis, K. Siegmund, C. Loddenkemper, J. Lowe +4 more
201023 citations
Semantic Scholar
T-cell trafficking into sites of inflammation.
A. Hamann, U. Syrbe
2000Rheumatology23 citations
Semantic Scholar
Microenvironment-Dependent Requirement of STAT4 for the Induction of P-Selectin Ligands and Effector Cytokines on CD4+ T Cells in Healthy and Parasite-Infected Mice1
U. Syrbe, U. Hoffmann, Kerstin Schlawe, O. Liesenfeld +2 more
2006Journal of Immunology19 citations Open access
Semantic Scholar
Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene
Matthias Pink, B. Ratsch, Maibritt Mardahl, P. Durek +14 more
2016Journal of Immunology17 citations
Semantic Scholar
An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus
Ursula Schulte‐Wrede, T. Sörensen, Joachim R. Grün, T. Häupl +8 more
2018Arthritis Research & Therapy16 citations Open access
Semantic Scholar
Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint
Fabian Karow, B. Smiljanovic, Joachim R. Grün, Denis Poddubnyy +14 more
2021Arthritis Research & Therapy14 citations Open access
Semantic Scholar
Long-Term Commitment to Inflammation-Seeking Homing in CD4+ Effector Cells1
S. Jennrich, B. Ratsch, A. Hamann, U. Syrbe
2007Journal of Immunology14 citations Open access
Semantic Scholar
Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4+ memory T cells
B. Szilagyi, Julia Triebus, C. Kressler, M. D. de Almeida +10 more
2017Mucosal Immunology10 citations Open access
Semantic Scholar
Bone marrow Th17 TNFα cells induce osteoclast differentiation and link bone destruction to IBD
U. Syrbe, B. Siegmund
2014Gut10 citations
Semantic Scholar
Accumulation and local proliferation of antigen‐specific CD4+ T cells in antigen‐bearing tissue
C. Doebis, A. Menning, K. Neumann, Saeed Ghani +5 more
2011Immunology and Cell Biology10 citations
Semantic Scholar
In situ analysis of interleukin-6 expression at different sites of zygapophyseal joints from patients with ankylosing spondylitis in comparison to controls
J. Bleil, R. Maier, U. Syrbe, J. Sieper +1 more
2015Scandinavian Journal of Rheumatology9 citations
Semantic Scholar
Differential regulation and impact of fucosyltransferase VII and core 2 β1,6‐N‐acetyl‐glycosaminyltransferase for generation of E‐selectin and P‐selectin ligands in murine CD4+ T cells
M. Schroeter, Boris A. Ratsch, J. Lehmann, R. Baumgrass +2 more
2012Immunology9 citations Open access
Semantic Scholar
Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model
S. M. Atkinson, J. Bleil, R. Maier, A. Kühl +8 more
2016Arthritis Research & Therapy8 citations Open access
Semantic Scholar
Identification of two regulatory elements controlling Fucosyltransferase 7 transcription in murine CD4+ T cells.
Matthias Pink, B. Ratsch, Maibritt Mardahl, M. F. Schröter +4 more
2014Molecular Immunology7 citations
Semantic Scholar
Regulation and Migratory Role of P-Selectin Ligands during Intestinal Inflammation
U. Hoffmann, Matthias Pink, Uta Lauer, M. Heimesaat +7 more
2013PLoS ONE5 citations Open access
Semantic Scholar
Core 2 ß1,6-N-acetylglucosaminyltransferase-I, crucial for P-selectin ligand expression is controlled by a distal enhancer regulated by STAT4 and T-bet in CD4+ T helper cells 1.
Maibritt Mardahl, M. F. Schröter, D. Engelbert, Matthias Pink +3 more
2016Molecular Immunology4 citations
Semantic Scholar
A6.09 Nk cells as biosensors for responsiveness to etanercept in ankylosing spondylitis (Morbus Bechterew)
Ursula Schulte-Wrede, T. Sörensen, J. Grün, U. Syrbe +4 more
20163 citations
Semantic Scholar
OP0091 Prediction of radiographic spinal progression using biomarkers in patients with ankylosing spondylitis who are at high risk for progression
D. Poddubnyy, K. Conrad, G. Ruiz-Heiland, U. Syrbe +5 more
20133 citations
Semantic Scholar
OP0141 No Signs for Direct Bone Formation or Endochondral Ossification at the Entheses in Facet Joints from Ankylosing Spondylitis Patients
J. Bleil, U. Syrbe, R. Maier, J. Sieper +1 more
20131 citations
Semantic Scholar
SAT0245 Elevated serum levels of sclerostin and periostin protect against syndesmophyte formation in patients with ankylosing spondylitis and high activity of systemic inflammation
D. Poddubnyy, K. Conrad, G. Ruiz-Heiland, U. Syrbe +5 more
20131 citations
Semantic Scholar
Selectin ligands on T cells.
A. Hamann, U. Syrbe, U. Kretschmer, S. Jennrich +1 more
2004Ernst Schering Research Foundation workshop1 citations
Semantic Scholar
Soluble programmed cell death-1 is increased in axial spondyloarthritis and present at the local site of pathology
E. Ahrenfeldt, M. Hvid, A. Jurik, U. Syrbe +4 more
2026Scandinavian Journal of Rheumatology0 citations
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Invasive fungal infections in patients with rheumatoid arthritis: an explorative analysis from the German RABBIT register
Alina Purschke, Vera Zietemann, P. Herzer, C. Kühne +4 more
2025RMD Open0 citations Open access
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