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A. Yoshimura · SciRah

Researcher profile · Semantic Scholar

A. Yoshimura

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A. Yoshimura — researcher profile on SciRah

h-index: 27
Works: 98
Citations: 2,211

Most-cited papers

MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells
M. Cao, M. Seike, Chie Soeno, H. Mizutani +6 more
2012International Journal of Oncology176 citations Open access
Semantic Scholar
The safety and efficacy of weekly paclitaxel in combination with carboplatin for advanced non-small cell lung cancer with idiopathic interstitial pneumonias.
Y. Minegishi, J. Sudoh, Hideaki Kuribayasi, H. Mizutani +5 more
2011Lung Cancer136 citations
Semantic Scholar
Reduction of PTEN protein and loss of epidermal growth factor receptor gene mutation in lung cancer with natural resistance to gefitinib (IRESSA)
Y. Kokubo, A. Gemma, R. Noro, M. Seike +7 more
2005British Journal of Cancer126 citations Open access
Semantic Scholar
Exacerbation of idiopathic interstitial pneumonias associated with lung cancer therapy.
Y. Minegishi, Kiyoshi Takenaka, H. Mizutani, J. Sudoh +8 more
2009Internal medicine122 citations Open access
Semantic Scholar
Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model
A. Miyanaga, A. Gemma, R. Noro, K. Kataoka +9 more
2008Molecular Cancer Therapeutics103 citations Open access
Semantic Scholar
Somatic mutation of the hBUB1 mitotic checkpoint gene in primary lung cancer
A. Gemma, M. Seike, Yoko Seike, K. Uematsu +6 more
2000Genes, Chromosomes and Cancer97 citations
Semantic Scholar
Three dimensional computed tomography lung modeling is useful in simulation and navigation of lung cancer surgery.
N. Ikeda, A. Yoshimura, M. Hagiwara, S. Akata +1 more
2013Annals of Thoracic and Cardiovascular Surgery94 citations Open access
Semantic Scholar
Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line.
A. Gemma, Kiyoshi Takenaka, Yoko Hosoya, K. Matuda +9 more
2001European Journal of Cancer94 citations
Semantic Scholar
Aberrations in the fragile histidine triad (FHIT) gene in idiopathic pulmonary fibrosis.
K. Uematsu, A. Yoshimura, A. Gemma, Hiroshi Mochimaru +12 more
2001Cancer Research71 citations
Semantic Scholar
The Feasibility Study of Carboplatin Plus Etoposide for Advanced Small Cell Lung Cancer with Idiopathic Interstitial Pneumonias
Y. Minegishi, Hidehiko Kuribayashi, K. Kitamura, H. Mizutani +7 more
2011Journal of Thoracic Oncology66 citations Open access
Semantic Scholar
Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation
R. Noro, A. Gemma, Seiji Kosaihira, Y. Kokubo +8 more
2006BMC Cancer63 citations Open access
Semantic Scholar
Phase I study of E7010
Kaichiro Yamamoto, K. Noda, A. Yoshimura, M. Fukuoka +2 more
1998Cancer Chemotherapy and Pharmacology62 citations
Semantic Scholar
PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors.
R. Noro, A. Gemma, A. Miyanaga, Seiji Kosaihira +9 more
2007International Journal of Oncology58 citations Open access
Semantic Scholar
Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4–ALK-rearranged non–small–cell lung cancer harbored coexisting EGFR mutation
A. Miyanaga, Kumi Shimizu, R. Noro, M. Seike +14 more
2013BMC Cancer56 citations Open access
Semantic Scholar
Anticancer drug clustering in lung cancer based on gene expression profiles and sensitivity database
A. Gemma, Cai Li, Yuka Sugiyama, K. Matsuda +12 more
2006BMC Cancer53 citations Open access
Semantic Scholar
Interstitial Lung Disease Onset and Its Risk Factors in Japanese Patients With ALK‐Positive NSCLC After Treatment With Crizotinib
A. Gemma, M. Kusumoto, Y. Kurihara, N. Masuda +6 more
2019Journal of Thoracic Oncology52 citations Open access
Semantic Scholar
Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers.
A. Gemma, Yoko Hosoya, M. Seike, K. Uematsu +6 more
2001Lung Cancer52 citations
Semantic Scholar
Bevacizumab plus chemotherapy for advanced non-squamous non-small-cell lung cancer with malignant pleural effusion
K. Kitamura, K. Kubota, M. Ando, Satoshi Takahashi +10 more
2013Cancer Chemotherapy and Pharmacology49 citations
Semantic Scholar
Increased expression of the LGALS3 (Galectin 3) gene in human non–small‐cell lung cancer
A. Yoshimura, A. Gemma, Yoko Hosoya, Eriko Komaki +11 more
2003Genes, Chromosomes and Cancer45 citations
Semantic Scholar
Alterations in novel candidate tumor suppressor genes, ING1 and ING2 in human lung cancer.
T. Okano, A. Gemma, Yoko Hosoya, Y. Hosomi +7 more
2006Oncology Report41 citations Open access
Semantic Scholar
Histone deacetylase inhibitor enhances sensitivity of non‐small‐cell lung cancer cells to 5‐FU/S‐1 via down‐regulation of thymidylate synthase expression and up‐regulation of p21waf1/cip1 expression
R. Noro, A. Miyanaga, Y. Minegishi, T. Okano +6 more
2010Cancer Science37 citations Open access
Semantic Scholar
MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation
R. Noro, M. Seike, Fenfei Zou, Chie Soeno +10 more
2015BMC Cancer35 citations Open access
Semantic Scholar
Weekly administration of irinotecan (CPT-11) plus cisplatin for refractory or relapsed small cell lung cancer.
M. Ando, Kunihiko Kobayashi, A. Yoshimura, F. Kurimoto +9 more
2004Lung Cancer34 citations
Semantic Scholar
Alteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis.
Yoko Hosoya, A. Gemma, Masahiro Seike, F. Kurimoto +5 more
1999Lung Cancer34 citations
Semantic Scholar
The promoter region of the human BUBR1 gene and its expression analysis in lung cancer.
M. Seike, A. Gemma, Yoko Hosoya, Y. Hosomi +8 more
2002Lung Cancer33 citations
Semantic Scholar
HSP27 modulates epithelial to mesenchymal transition of lung cancer cells in a Smad-independent manner.
H. Mizutani, T. Okano, Y. Minegishi, K. Matsuda +7 more
2010Oncology Letters31 citations Open access
Semantic Scholar
Docetaxel in Combination with Either Cisplatin or Gemcitabine in Unresectable Non-small Cell Lung Carcinoma: A Randomized Phase II Study by the Japan Lung Cancer Cooperative Clinical Study Group
N. Katakami, Y. Takiguchi, K. Yoshimori, H. Isobe +3 more
2006Journal of Thoracic Oncology28 citations Open access
Semantic Scholar
Reduced transcription of the Smad4 gene during pulmonary carcinogenesis in idiopathic pulmonary fibrosis.
Kiyoshi Takenaka, A. Gemma, A. Yoshimura, Yoko Hosoya +9 more
2009Molecular Medicine Reports27 citations Open access
Semantic Scholar
Somatic mutation of the Caspase-5 gene in human lung cancer.
Y. Hosomi, Akihiko Gemma, Yoko Hosoya, Michiya Nara +6 more
2003International Journal of Molecular Medicine21 citations
Semantic Scholar
Association between F-18 fluorodeoxyglucose uptake of noncancerous lung area and acute exacerbation of interstitial pneumonia in patients with lung cancer after resection.
T. Yamamichi, Y. Shimada, R. Masuno, T. Ohira +3 more
2020Journal of Thoracic and Cardiovascular Surgery20 citations Open access
Semantic Scholar
Cross-cultural validation of the Japanese Functional Assessment of Cancer Therapy-Anemia (FACT-An).
A. Yoshimura, Kunihiko Kobayashi, H. Fumimoto, Yuki Fujiki +2 more
2004Journal of Nippon Medical School = Nippon Ika Daigaku zasshi20 citations Open access
Semantic Scholar
Reduced transcription of the RB2/p130 gene in human lung cancer
Hu-Xue Jun, A. Gemma, Yoko Hosoya, K. Matsuda +9 more
2003Molecular Carcinogenesis18 citations Open access
Semantic Scholar
Unchanged frequency of loss of heterozygosity and size of the deleted region at 8p21-23 during metastasis of lung cancer.
F. Kurimoto, A. Gemma, Yoko Hosoya, M. Seike +5 more
2001International Journal of Molecular Medicine18 citations
Semantic Scholar
E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib.
A. Miyanaga, A. Gemma, M. Ando, Seiji Kosaihira +13 more
2008Oncology Report16 citations Open access
Semantic Scholar
How Wild-Type TP53 Is Inactivated in Undifferentiated-Type Gastric Carcinomas: Analyses of Intratumoral Heterogeneity in Deletion and Mutation of TP53
A. Yoshimura, H. Sugihara, Zhi-Qiang Ling, D. Peng +3 more
2006Pathobiology (Basel)16 citations
Semantic Scholar
Mutation analysis of the gene encoding the human mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in human cell lines resistant to growth inhibition by transforming growth factor beta(1) (TGF-beta(1)).
A. Gemma, Yoko Hosoya, K. Uematsu, Masahiro Seike +4 more
2000Lung Cancer16 citations
Semantic Scholar
Glasgow Prognostic Score predicts chemotherapy‐triggered acute exacerbation‐interstitial lung disease in patients with non‐small cell lung cancer
R. Kikuchi, H. Takoi, T. Tsuji, Yoko Nagatomo +10 more
2021Thoracic Cancer15 citations Open access
Semantic Scholar
Treatment status and safety of crizotinib in 2028 Japanese patients with ALK-positive NSCLC in clinical settings.
Naomi Ueno, Shigeo Banno, Y. Endo, Motoko Tamura +5 more
2019Japanese Journal of Clinical Oncology15 citations Open access
Semantic Scholar
Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules
T. Shimokawa, M. Seike, Chie Soeno, Haruka Uesaka +8 more
2012British Journal of Cancer14 citations Open access
Semantic Scholar
Glasgow prognostic score for prediction of chemotherapy‐triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer
R. Kikuchi, H. Takoi, T. Tsuji, Yoko Nagatomo +10 more
2021Thoracic Cancer13 citations Open access
Semantic Scholar
Interstitial pneumonia complicated by Sjögren's syndrome, Hashimoto's disease, rheumatoid arthritis and primary biliary cirrhosis.
H. Miyamoto, A. Azuma, Y. Taniguchi, Takuo Takahashi +4 more
2000Internal medicine13 citations Open access
Semantic Scholar
Alternating chemotherapy with amrubicin plus cisplatin and weekly administration of irinotecan plus cisplatin for extensive-stage small cell lung cancer.
R. Noro, A. Yoshimura, Kazuo Yamamoto, A. Miyanaga +12 more
2013Anticancer Research10 citations
Semantic Scholar
[Iressa (gefitinib)].
S. Kudoh, A. Yoshimura, A. Gemma
2003Gan to kagaku ryoho. Cancer & chemotherapy10 citations
Semantic Scholar
Pilot trial of a combination comprising of consecutive oral administration of UFT, and two-divided administration of CDDP in non-small cell lung cancer.
A. Gemma, Shoji Kudoh, A. Yoshimura, Y. Ono +5 more
1995Anticancer Research9 citations
Semantic Scholar
Phase I/II study of docetaxel and S-1, an oral fluorinated pyrimidine, for untreated advanced non-small cell lung cancer.
Y. Takiguchi, Yuji Tada, A. Gemma, S. Kudoh +5 more
2010Lung Cancer8 citations
Semantic Scholar
Weekly administration of irinotecan (CPT-11) plus cisplatin for non-small cell lung cancer.
M. Hino, Kunihiko Kobayashi, A. Yoshimura, Y. Takeda +5 more
2006Anticancer Research6 citations
Semantic Scholar
Phase I/II study of paclitaxel + carboplatin for refractory or recurrent non-small cell lung cancer.
A. Gemma, M. Seike, Seiji Kosaihira, Y. Minegishi +8 more
2006Anticancer Research6 citations
Semantic Scholar
Augmented Lung Adenocarcinoma Cytotoxicity by the Combination of a Genetically Modified Anti‐Lewis Y Antibody and Antibodies to Complement Regulatory Proteins
A. Azuma, Y. Yamano, A. Yoshimura, T. Hibino +7 more
1995Scandinavian Journal of Immunology6 citations
Semantic Scholar
Phase I/II study of combination chemotherapy of CDDP and CBDCA in patients with non small cell lung cancer
A. Gemma, A. Yoshimura, Kunihiko Kobayashi, Y. Taniguchi +3 more
19916 citations
Semantic Scholar
Combination chemotherapy of alternating etoposide and carboplatin with weekly administration of irinotecan and cisplatin in extensive-stage small-cell lung cancer.
A. Yoshimura, R. Noro, A. Miyanaga, H. Mizutani +9 more
2012Anticancer Research4 citations
Semantic Scholar

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A. Gemma×38
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A. Gemma — researcher profile on SciRah
M. Seike×26
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M. Seike — researcher profile on SciRah
S. Kudoh×23
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S. Kudoh — researcher profile on SciRah
T. Okano×20
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T. Okano — researcher profile on SciRah

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Y. Minegishi — researcher profile on SciRah

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R. Noro — researcher profile on SciRah

Yoko Hosoya×12

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Yoko Hosoya — researcher profile on SciRah

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K. Uematsu — researcher profile on SciRah

Seiji Kosaihira×11

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Seiji Kosaihira — researcher profile on SciRah

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K. Matsuda — researcher profile on SciRah

Michiya Nara×10

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Michiya Nara — researcher profile on SciRah

Kiyoshi Takenaka×9

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Kiyoshi Takenaka — researcher profile on SciRah