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N. Gerwin · SciRah

Researcher profile · Semantic Scholar

N. Gerwin

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N. Gerwin — researcher profile on SciRah

h-index: 19
Works: 46
Citations: 2,694

Most-cited papers

The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat.
N. Gerwin, A. Bendele, S. Glasson, C. Carlson
2010Osteoarthritis and Cartilage705 citations Open access
Semantic Scholar
Intraarticular drug delivery in osteoarthritis.
N. Gerwin, Caroline Hops, Andrea Lucke
2006Advanced Drug Delivery Reviews461 citations
Semantic Scholar
Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis.
K. Rudolphi, N. Gerwin, N. Verzijl, P. M. van der Kraan +1 more
2003Osteoarthritis and Cartilage210 citations Open access
Semantic Scholar
Histopathology atlas of animal model systems - overview of guiding principles.
T. Aigner, J. Cook, N. Gerwin, S. Glasson +4 more
2010Osteoarthritis and Cartilage178 citations Open access
Semantic Scholar
T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells.
Ruth Lyck, Y. Reiss, N. Gerwin, J. Greenwood +2 more
2003Blood169 citations
Semantic Scholar
Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the Drosophila embryo.
M. Pankratz, E. Seifert, N. Gerwin, B. Billi +2 more
1990Cell139 citations
Semantic Scholar
ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration.
Miao-Tzu Huang, Karen Y. Larbi, C. Scheiermann, A. Woodfin +3 more
2006Blood134 citations Open access
Semantic Scholar
Competition for overlapping sites in the regulatory region of the Drosophila gene Krüppel.
M. Hoch, N. Gerwin, Heike Taubert, H. Jäckle
1992Science133 citations
Semantic Scholar
Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness.
N. Gerwin, J. Gonzalo, Clare M. Lloyd, A. Coyle +8 more
1999Immunity130 citations Open access
Semantic Scholar
Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone.
Rishard Salie, M. Kneissel, Mirko Vukevic, N. Zamurović +6 more
2010Bone70 citations
Semantic Scholar
Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial
N. Gerwin, C. Scotti, C. Halleux, M. Fornaro +26 more
2022Nature Medicine59 citations Open access
Semantic Scholar
ADAMTS-1, a gene product of articular chondrocytes in vivo and in vitro, is downregulated by interleukin 1beta.
L. Wachsmuth, B. Bau, Zhi-Yong Fan, A. Pecht +2 more
2004Journal of Rheumatology41 citations
Semantic Scholar
Transcriptional control by Drosophila gap genes
H. Jäckle, M. Hoch, M. Pankratz, N. Gerwin +2 more
1992Journal of Cell Science36 citations Open access
Semantic Scholar
Schmits, R. et al. CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity. Blood 90, 2217-2233
R. Schmits, J. Filmus, N. Gerwin, G. Senaldi +13 more
199729 citations
Semantic Scholar
Functional and conserved domains of the Drosophila transcription factor encoded by the segmentation gene knirps
N. Gerwin, A. La Rosée, F. Sauer, H. Halbritter +3 more
1994Molecular and Cellular Biology26 citations Open access
Semantic Scholar
Cloning, expression analysis, and functional characterization of PKL12, a member of a new subfamily of ser/thr kinases.
J. Ligos, N. Gerwin, Piedad Fernández, J. Gutiérrez-Ramos +1 more
1998Biochemical and Biophysical Research Communications - BBRC25 citations
Semantic Scholar
Pattern formation in Drosophila.
H. Jckle, U. Gaul, U. Nauber, N. Gerwin +4 more
1989Seminars in Cell Biology23 citations
Semantic Scholar
Growth plate cartilage as developmental model in osteoarthritis research--potentials and limitations.
Thomas Aigner, N. Gerwin
2007Current Drug Targets22 citations
Semantic Scholar
Reprints Available Directly from the Publisher Photocopying Permitted by License Only Interleukin Gene Expression in Mouse Preimplantation Development
N. Gerwin, G. Jia, R. Kulbacki, J. Gutierrezramos
21 citations
Semantic Scholar
Nucleotide sequence of the dcm locus of Escherichia coli K12.
Theodor Hanck, N. Gerwin, Hans-Joachim Fritz
1989Nucleic Acids Research19 citations Open access
Semantic Scholar
Sporozoites of Plasmodium yoelii infect mice with targeted deletions in ICAM-1 and ICAM-2 or complement components C3 and C4.
A. Sultan, M. R. Briones, N. Gerwin, Michael C. Carroll +1 more
1997Molecular and biochemical parasitology (Print)16 citations Open access
Semantic Scholar
Multiple antigens are altered on T and B lymphocytes from peripheral blood and spleen of patients with Wiskott–Aldrich syndrome
N. Gerwin, C. Friedrich, Antonio R. Perez-Atayde, F. Rosen +1 more
1996Clinical and Experimental Immunology16 citations Open access
Semantic Scholar
Toward designing human intervention studies to prevent osteoarthritis after knee injury: A report from an interdisciplinary OARSI 2023 workshop
Jackie L. Whittaker, R. Kalsoum, James Bilzon, P. Conaghan +17 more
2024Osteoarthritis and Cartilage Open12 citations Open access
Semantic Scholar
High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor
Paul J. Groot-Kormelink, Sandrine Ferrand, Nicholas Kelley, A. Bill +10 more
2016PLoS ONE9 citations Open access
Semantic Scholar
Positive allosteric modulator selective for adult muscle nicotinic acetylcholine receptor
Richard G Webster, S. Alabaf, Anna Li, R. Beerli +10 more
2026Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
First-in-human trial results of LNA043, a novel cartilage regenerative treatment for osteoarthritis
C. Scotti, J. Gimbel, D. Laurent, Á. Madár +10 more
20212 citations Open access
Semantic Scholar
Effect of Calstabin1 Depletion on Calcium Transients and Energy Utilization in Muscle Fibers and Treatment Opportunities with RyR1 Stabilizers
Anke Breckner, Magdalena Ganz, D. Marcellin, Jens Richter +2 more
2013PLoS ONE2 citations Open access
Semantic Scholar
Drug delivery in degenerative joint disease.
T. Aigner, N. Gerwin
2006Advanced Drug Delivery Reviews2 citations
Semantic Scholar
Validation of a diffusion chamber as in vitro system for the analysis of compound diffusibility through cartilage tissue.
Alexander Kreiselmeier, W. Ulmer, J. Stöve, H. Wieland +7 more
2005Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2 citations
Semantic Scholar
Pathology and Development - Developmental Systems for Target Validation and Drug Screening in Osteoarthritis
N. Gerwin, T. Pellas, U. Junker, T. Aigner
20052 citations
Semantic Scholar
Dynamics of matrix loss in the spontaneous osteoarthritic mouse strain STR-1N
Lydia K. Wachsmuth, B. Durchfeld-Meyer, N. Jahn, N. Verzijl +5 more
20022 citations
Semantic Scholar
Musterbildung bei Drosophila
H. Jäckle, Ulrike Gaul, Ulrich Nauber, N. Gerwin +4 more
1989SCIENCE NATURE2 citations
Semantic Scholar
Regeneration of hyaline cartilage in response to a single injection of LNA043, an ANGPTL3 mimetic, in the knee of patients with a focal cartilage defect
D. Laurent, C. Scotti, M. Schreiner, M. Neubauer +11 more
20211 citations Open access
Semantic Scholar
DNA-Binding Proteins in Drosophila Development
M. Pankratz, M. Hoch, M. Rothe, U. Nauber +4 more
19901 citations
Semantic Scholar
Early development of LRX712, preclinical chondroanabolic findings and results from a randomized first-in-human study
A. Meijs, J. P. M. Vrouwe, F. Saxer, I. Kramer +23 more
2026Arthritis Research & Therapy0 citations Open access
Semantic Scholar
LNA043 and ANGPTL3 Interactions with Integrin α5β1 and Fibronectin Drive Distinct Stromal and Immune Responses
Andrea Grosso, Stefano Cucuzza, Elsa Gambs, Thomas Lapointe +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
LNA043 A NOVEL CANDIDATE FOR OSTEOARTHRITIS TREATMENT INDUCES CARTILAGE REGENERATION AND REVERSES THE OSTEOARTHRITIS TRANSCRIPTOME
N. Gerwin, C. Halleux, M. Fornaro, J. Elliott +13 more
2022Osteoarthritis and Cartilage0 citations Open access
Semantic Scholar
Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies
S. Siehler, Sandrine Ferrand, Nicholas Kelley, A. Bill +10 more
2017The FASEB Journal0 citations Open access
Semantic Scholar
Temporal profile curves for calcium transients during single twitch activation (A) and tetanic stimulation (B).
Anke Breckner, Magdalena Ganz, D. Marcellin, Jens Richter +2 more
20130 citations Open access
Semantic Scholar
angiogenesis Endothelial intercellular adhesion molecule (ICAM)-2 regulates
A. Ridley, J. Mason, V. Amsellem, N. Gerwin
20130 citations
Semantic Scholar
Effect of Calstabin 1 Depletion on Calcium Transients and Energy Utilization in Muscle Fibers and Treatment Opportunities with RyR 1 Stabilizers
Anke Breckner, Magdalena Ganz, D. Marcellin, Jens Richter +2 more
20130 citations
Semantic Scholar
angiogenesis 2 regulates - Endothelial intercellular adhesion molecule (ICAM)
A. Ridley, A. Randi, Miao-Tzu Huang, J. Mason +3 more
20130 citations
Semantic Scholar
Formation, and Tumorigenicity CD44 Regulates Hematopoietic Progenitor Distribution, Granuloma
P. Ohashi, C. Paige, J. Gutiérrez-Ramos, T. Mak +12 more
20130 citations
Semantic Scholar
Intercellular adhesion molecule (ICAM)-2 mediates angiogenesis via homophilic interaction
M.-T. Huang, J. Mason, N. Gerwin, A. Ridley +2 more
20050 citations
Semantic Scholar
, H segmentation gene knirps . Drosophila transcription factor encoded by the Functional and conserved domains of the
N. Gerwin, A. La Rosée, F. Sauer, H. Halbritter +1 more
19940 citations
Semantic Scholar
[Pattern formation in Drosophila].
H. Jckle, U. Gaul, U. Nauber, N. Gerwin +4 more
1989Die Naturwissenschaften0 citations
Semantic Scholar

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