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Kevin Van Bortle · SciRah

Researcher profile · Semantic Scholar

Kevin Van Bortle

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Kevin Van Bortle — researcher profile on SciRah

h-index: 19
Works: 47
Citations: 1,690

Most-cited papers

Insulator function and topological domain border strength scale with architectural protein occupancy
Kevin Van Bortle, Michael H. Nichols, Li Li, Chin-Tong Ong +3 more
2014Genome Biology292 citations Open access
Semantic Scholar
Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development
D. Phanstiel, Kevin Van Bortle, D. Spacek, G. Hess +6 more
2017bioRxiv278 citations Open access
Semantic Scholar
Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains
Kevin Van Bortle, Edward Ramos, Naomi Takenaka, Jingping Yang +2 more
2012Genome Research127 citations Open access
Semantic Scholar
Nuclear Organization and Genome Function
Kevin Van Bortle, V. Corces
2012Annual Review of Cell and Developmental Biology125 citations Open access
Semantic Scholar
Regulation of chromatin organization and inducible gene expression by a Drosophila insulator
Ashley M. Wood, Kevin Van Bortle, Edward Ramos, Naomi Takenaka +4 more
2011Molecules and Cells120 citations Open access
Semantic Scholar
Genome-Wide Temporal Profiling of Transcriptome and Open-Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs
Qing Liu, Chao Jiang, Jin Xu, Ming-Tao Zhao +6 more
2017Circulation Research119 citations Open access
Semantic Scholar
Poly(ADP-ribosyl)ation regulates insulator function and intra-chromosomal interactions in Drosophila
Chin-Tong Ong, Kevin Van Bortle, Edward Ramos, V. Corces
2013Cell69 citations Open access
Semantic Scholar
The role of chromatin insulators in nuclear architecture and genome function
Kevin Van Bortle, V. Corces
2013Current Opinion in Genetics and Development64 citations Open access
Semantic Scholar
tDNA insulators and the emerging role of TFIIIC in genome organization
Kevin Van Bortle, V. Corces
2012Transcription57 citations Open access
Semantic Scholar
Genome-wide phosphoacetylation of histone H3 at Drosophila enhancers and promoters
Wendy A. Kellner, Edward Ramos, Kevin Van Bortle, Naomi Takenaka +1 more
2012Genome Research55 citations Open access
Semantic Scholar
Dynamic changes in the genomic localization of DNA replication-related element binding factor during the cell cycle
B. Gurudatta, Jingping Yang, Kevin Van Bortle, Paul G. Donlin-Asp +1 more
2013Cell Cycle46 citations Open access
Semantic Scholar
Topological organization and dynamic regulation of human tRNA genes during macrophage differentiation
Kevin Van Bortle, D. Phanstiel, M. Snyder
2017Genome Biology44 citations Open access
Semantic Scholar
Intranuclear dynamics of the Nup107-160 complex
Stéphanie Morchoisne-Bolhy, M. Geoffroy, I. Bouhlel, A. Alves +5 more
2015Molecular Biology of the Cell40 citations Open access
Semantic Scholar
Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites
Wendy A. Kellner, Kevin Van Bortle, Li Li, Edward Ramos +2 more
2013Nucleic Acids Research38 citations Open access
Semantic Scholar
The Pol III transcriptome: Basic features, recurrent patterns, and emerging roles in cancer
Sihang Zhou, Kevin Van Bortle
2023Wiley Interdisciplinary Reviews - RNA33 citations Open access
Semantic Scholar
A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA
Kevin Van Bortle, David P. Marciano, Qing Liu, T. Chou +6 more
2021Nature Communications26 citations Open access
Semantic Scholar
Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
Qing Liu, Kevin Van Bortle, Yue Zhang, Ming-Tao Zhao +6 more
2018Scientific Reports26 citations Open access
Semantic Scholar
Spinning the Web of Cell Fate
Kevin Van Bortle, V. Corces
2013Cell26 citations Open access
Semantic Scholar
CTCF-dependent co-localization of canonical Smad signaling factors at architectural protein binding sites in D. melanogaster
Kevin Van Bortle, Aidan J. Peterson, Naomi Takenaka, M. O'Connor +1 more
2015Cell Cycle23 citations Open access
Semantic Scholar
Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters
K. Rajendra, Rui-Ying Cheng, Si-Hang Zhou, Simon Lizarazo +2 more
2024bioRxiv12 citations Open access
Semantic Scholar
Chimpanzee and pig-tailed macaque iPSCs: improved culture and generation of primate cross-species embryos
M. Roodgar, Fabian P. Suchy, L. H. Nguyen, V. Bajpai +17 more
2022Cell Reports11 citations Open access
Semantic Scholar
Lost in Transition: Dynamic Enhancer Organization across Naive and Primed Stem Cell States
Kevin Van Bortle, V. Corces
2014Cell Stem Cell9 citations Open access
Semantic Scholar
Cholesterol efflux protein, ABCA1, supports anticancer functions of myeloid immune cells
Shruti V. Bendre, Yu Wang, Basel Hajyousif, Rajendra K. C. +28 more
2026Science Advances8 citations Open access
Semantic Scholar
Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters
Rajendra K. C., Rui-Ying Cheng, Si-Hang Zhou, Simon Lizarazo +2 more
2024Molecules and Cells8 citations Open access
Semantic Scholar
RNA polymerase III transcription and cancer: A tale of two RPC7 subunits
Ruiying Cheng, Kevin Van Bortle
2023Frontiers in Molecular Biosciences8 citations Open access
Semantic Scholar
Integrated tRNA, transcript, and protein profiles in response to steroid hormone signaling
Kevin Van Bortle, Michael H. Nichols, Edward Ramos, V. Corces
2015RNA: A publication of the RNA Society7 citations Open access
Semantic Scholar
MANCR lncRNA Modulates Cell-Cycle Progression and Metastasis by Cis-Regulation of Nuclear Rho-GEF
D. K. Singh, Zhengmin Cong, You-Jin Song, Minxue Liu +15 more
2024Molecular and Cellular Biology6 citations Open access
Semantic Scholar
A Combinatorial Regulatory Platform Determines Expression of RNA Polymerase III Subunit RPC7α (POLR3G) in Cancer
Rui-Ying Cheng, Si-Hang Zhou, Rajendra K. C., Simon Lizarazo +4 more
2023Cancers5 citations Open access
Semantic Scholar
The NuRD complex shapes RNA polymerase III activity at highly expressed tRNA gene clusters, tuning the dynamic range of cellular tRNA pools.
Rui-Ying Cheng, Rajendra K. C., Simon Lizarazo, Jun-Meng Yuan +3 more
2026Cell Reports2 citations Open access
Semantic Scholar
Cholesterol efflux protein, ABCA1, supports anti-cancer functions of myeloid immune cells
Shruti V. Bendre, Yu Wang, Basel Hajyousif, K. Rajendra +24 more
2025bioRxiv2 citations Open access
Semantic Scholar
Abstract A048: The Loss of Cholesterol Efflux Pump ABCA1 Skews Macrophages Towards a Pro-tumor Phenotype and Facilitates Breast Cancer Progression
Shruti V. Bendre, Natalia Krawczynska, Shaunak Bhogale, Erin Weisser +16 more
2024Cancer immunology research2 citations
Semantic Scholar
An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms.
Simon Lizarazo, Si-Hang Zhou, Rui-Ying Cheng, Rajendra K. C. +4 more
2026Genome Research1 citations Open access
Semantic Scholar
Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations
Si-Hang Zhou, Simon Lizarazo, Sandip Chorghade, Leela Mouli +4 more
2025Nature Communications1 citations Open access
Semantic Scholar
Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations
Si-Hang Zhou, Simon Lizarazo, Leela Mouli, Sandip Chorghade +4 more
2024bioRxiv1 citations Open access
Semantic Scholar
Tyrosine kinase inhibitors induce mitochondrial dysfunction during cardiomyocyte differentiation through alteration of GATA4-mediated networks
Qing Liu, Hao-Di Wu, Qing-Jun Luo, Chao Jiang +23 more
2020bioRxiv1 citations Open access
Semantic Scholar
Insulator function and topological domain border strength scale with architectural protein occupancy
Kevin Van Bortle, Michael H. Nichols, Li Li, Chin-Tong Ong +3 more
2014Genome Biology1 citations Open access
Semantic Scholar
ATF4 Modulates Group 1 mGluR-Dependent molecular signaling, hippocampal plasticity and behavior.
Shi-Yu Wang, Yeeun Yook, Simon Lizarazo, Kwan Lee +4 more
2026Molecular Psychiatry0 citations Open access
Semantic Scholar
Abstract 5012: Multiomic profiling reveals ligand and cell specific regulatory programs of LXR selective modulation in myeloid immune cells
Yi-Fan Fei, Rajendra K. C., M. Flory, Natalia Krawczynska +4 more
2026Cancer Research0 citations
Semantic Scholar
Reciprocal effective conductance-based inference of protein-protein relationships delineates protein network hubs and macromolecular properties
K. Rajendra, Si-Hang Zhou, Rui-Ying Cheng, Marco Andres Penaherrera +2 more
2026bioRxiv0 citations Open access
Semantic Scholar
The NuRD complex shapes RNA polymerase III activity at highly expressed tRNA gene clusters, tuning the dynamic range of cellular tRNA pools
Rui-Ying Cheng, K. Rajendra, Simon Lizarazo, Jun-Meng Yuan +2 more
2025bioRxiv0 citations Open access
Semantic Scholar
An RNA polymerase III tissue and tumor atlas uncovers context-specific activities linked to 3D epigenome regulatory mechanisms
Simon Lizarazo, Si-Hang Zhou, Rui-Ying Cheng, K. Rajendra +3 more
2025bioRxiv0 citations
Semantic Scholar
Abstract B063: The cholesterol efflux protein, ABCA1, plays a critical role in modulating anti-tumor myeloid immune cell functions
Shruti V. Bendre, Natalia Krawczynska, Rajendra K. C., Yu Wang +17 more
2025Cancer immunology research0 citations
Semantic Scholar
Abstract 174: Cholesterol efflux protein ABCA1 skews macrophages towards an anti-tumor phenotype and consequently impacts breast cancer progression
Shruti V. Bendre, Natalia Krawczynska, Shaunak Bhogale, Erin Weisser +14 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 10300: Crosstalk Between GATA4 and Mitochondria During Cardiomyocyte Differentiation Upon Exposure to Tyrosine Kinase Inhibitors
Qing Liu, Hao-Di Wu, Ming-Tao Zhao, Chao Jiang +5 more
20180 citations
Semantic Scholar
enhancers and promoters Drosophila Genome-wide phosphoacetylation of histone H 3 at Material Supplemental
Edward Ramos, Kevin Van Bortle, Naomi Takenaka, V. Corces
20120 citations
Semantic Scholar
the borders of H 3 K 27 me 3 domains CTCF tandemly aligns with other insulator proteins at Drosophila Material Supplemental
Kevin Van Bortle, Edward Ramos, Naomi Takenaka, D. Schmidt +4 more
20120 citations
Semantic Scholar
Faculty Opinions recommendation of Yeast pre-rRNA processing and modification occur cotranscriptionally.
D. Reines, Kevin Van Bortle
20100 citations
Semantic Scholar

Frequent co-authors

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V. Corces×16
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V. Corces — researcher profile on SciRah
Simon Lizarazo×12
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Simon Lizarazo — researcher profile on SciRah
Rui-Ying Cheng×10
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Rui-Ying Cheng — researcher profile on SciRah
Si-Hang Zhou×10
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Rajendra K. C. — researcher profile on SciRah

Naomi Takenaka×9

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Naomi Takenaka — researcher profile on SciRah

Edward Ramos×8

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Edward Ramos — researcher profile on SciRah

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M. Snyder — researcher profile on SciRah

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K. Rajendra — researcher profile on SciRah

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Yu Wang — researcher profile on SciRah

Natalia Krawczynska×6

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Qing Liu — researcher profile on SciRah