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J. Gaifem · SciRah

Researcher profile · Semantic Scholar

J. Gaifem

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J. Gaifem — researcher profile on SciRah

h-index: 18
Works: 36
Citations: 1,015

Most-cited papers

Immune regulatory networks coordinated by glycans and glycan-binding proteins in autoimmunity and infection
S. Pinho, Inês Alves, J. Gaifem, G. Rabinovich
2023Cellular & Molecular Immunology188 citations Open access
Semantic Scholar
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity
Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Cláudia F. Campos, V. Aimanianda +30 more
2020Nature Communications102 citations Open access
Semantic Scholar
Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling
Lúcia Moreira-Teixeira, J. Sousa, Finlay W Mcnab, E. Torrado +10 more
2016Journal of Immunology99 citations Open access
Semantic Scholar
Akkermansia muciniphila and Parabacteroides distasonis synergistically protect from colitis by promoting ILC3 in the gut
J. Gaifem, Ana Mendes-Frias, Mathis Wolter, Alex Steimle +11 more
2024mBio69 citations Open access
Semantic Scholar
Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn’s Disease
A. Mortha, R. Remark, D. Del Valle, Ling-Shiang Chuang +31 more
2022Gastroenterology64 citations Open access
Semantic Scholar
A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan
J. Gaifem, Cláudia S Rodrigues, F. Petralia, Inês Alves +17 more
2024Nature Immunology53 citations Open access
Semantic Scholar
Exploring NAD+ metabolism in host–pathogen interactions
Inês Mesquita, Patrícia Varela, Ana Belinha, J. Gaifem +4 more
2016Cellular and Molecular Life Sciences53 citations Open access
Semantic Scholar
IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.
C. Cunha, Samuel M. Gonçalves, Cláudio Duarte-Oliveira, L. Leite +26 more
2017Journal of Allergy and Clinical Immunology49 citations Open access
Semantic Scholar
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity
M. Vicente, Inês Alves, J. Gaifem, C. Rodrigues +14 more
2022European Journal of Immunology44 citations Open access
Semantic Scholar
Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity
Ângela Brito, J. Gaifem, V. Ramos, Evgenia Glukhov +5 more
201534 citations Open access
Semantic Scholar
Sphingolipid signaling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1
Rita Vilaça, E. Silva, André Nadais, Vitor Teixeira +5 more
2013Molecular Microbiology34 citations Open access
Semantic Scholar
Composition of the immunoglobulin G glycome associates with the severity of COVID-19
T. Petrović, Inês Alves, D. Bugada, J. Pascual +26 more
2020medRxiv29 citations Open access
Semantic Scholar
IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages
A. Cruz, P. Ludovico, E. Torrado, José B. Gama +8 more
2015Frontiers in Immunology29 citations Open access
Semantic Scholar
The role of glycans in health and disease: Regulators of the interaction between gut microbiota and host immune system.
Lucy I. Crouch, Cláudia S Rodrigues, Cassie R. Bakshani, L. Tavares-Gomes +2 more
2024Seminars in Immunology27 citations Open access
Semantic Scholar
L-Threonine Supplementation During Colitis Onset Delays Disease Recovery
J. Gaifem, Luís G. Gonçalves, R. Dinis-Oliveira, C. Cunha +6 more
2018Frontiers in Physiology25 citations Open access
Semantic Scholar
Definition of the Anti-inflammatory Oligosaccharides Derived From the Galactosaminogalactan (GAG) From Aspergillus fumigatus
Markus Gressler, C. Heddergott, Inès N'Go, G. Renga +8 more
2019Frontiers in Cellular and Infection Microbiology23 citations Open access
Semantic Scholar
Influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages
C. R. Correia, J. Gaifem, Mariana B. Oliveira, R. Silvestre +1 more
2017Biomaterials Science23 citations Open access
Semantic Scholar
Dysregulation of glycerophospholipid metabolism during Behçet’s disease contributes to a pro-inflammatory phenotype of circulating monocytes
Ana Mendes-Frias, Bruno Santos-Lima, D. Furtado, F. Rupérez +8 more
2020Journal of Translational Autoimmunity18 citations Open access
Semantic Scholar
Akkermansia muciniphila and Parabacteroides distasonis as prognostic markers for relapse in ulcerative colitis patients
Ana Mendes-Frias, M. Moreira, Maria C. Vieira, J. Gaifem +3 more
2024Frontiers in Cellular and Infection Microbiology14 citations Open access
Semantic Scholar
Alterations in mucosa branched N-glycans lead to dysbiosis and downregulation of ILC3: a key driver of intestinal inflammation
Cláudia S Rodrigues, J. Gaifem, M. Pereira, M. Alves +11 more
2025Gut microbes10 citations Open access
Semantic Scholar
SARS-CoV-2 Infection Drives a Glycan Switch of Peripheral T Cells at Diagnosis
Inês Alves, M. M. Vicente, J. Gaifem, Â. Fernandes +8 more
2021Journal of Immunology9 citations Open access
Semantic Scholar
The Role of Glycosylation in Inflammatory Diseases.
Inês Alves, M. Vicente, A. Dias, J. Gaifem +3 more
2021Advances in Experimental Medicine and Biology7 citations
Semantic Scholar
Mathematical Modelling Using Predictive Biomarkers for the Outcome of Canine Leishmaniasis upon Chemotherapy
Rafaela Rodrigues de Sousa Gonçalves, Flaviane Alves de Pinho, R. Dinis-Oliveira, Rui Azevedo +6 more
2020Microorganisms7 citations Open access
Semantic Scholar
Branched-Chain Amino Acids Exacerbate Colitis Progression by Lowering Colonic Fumarate Levels.
Ana Mendes-Frias, Maria C. Vieira, Marta Araújo, Cláudio Duarte-Oliveira +14 more
2025Inflammatory Bowel Diseases4 citations
Semantic Scholar
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation
N. Domingues, J. Gaifem, R. Matthiesen, D. P. Saraiva +19 more
2023bioRxiv4 citations Open access
Semantic Scholar
Anti-GM-CSF autoantibodies promote a pre-diseased state in Crohns Disease.
A. Mortha, Romain Remark, D. Del Valle, Ling-Shiang Chuang +30 more
2021medRxiv1 citations Open access
Semantic Scholar
The Role of Glycans in Chronic Inflammatory Gastrointestinal and Liver Disorders and Cancer
Â. Fernandes, A. Dias, M. Silva, J. Gaifem +3 more
20201 citations
Semantic Scholar
Treg-associated oligomannose N-glycans trigger immune dysregulation in myasthenia gravis.
P. Carneiro, M. M. Vicente, Inês Alves, C. Azevedo +7 more
2026Journal of Autoimmunity0 citations Open access
Semantic Scholar
418: CHANGES IN CELLULAR GLYCOSYLATION ARE ASSOCIATED WITH AN INCREASED INTESTINAL PERMEABILITY AND PRECEDE BY UP TO 6 YEARS THE DEVELOPMENT OF CRONHS DISEASE.
J. Gaifem, Cláudia S Rodrigues, L. Tavares-Gomes, Gonçalo Barreto +4 more
2025Gastroenterology0 citations
Semantic Scholar
P0034 Glycosylation as new molecular mechanism underlying Pediatric Inflammatory Bowel Disease
R. Amorim, B. Santos-Pereira, A. M. Días, B. S. Pinto +6 more
2025Journal of Crohn's & Colitis0 citations
Semantic Scholar
Changes in the glycosylation of circulating IgG predict future Crohn’s disease onset
J. Gaifem, Salomé S. Pinho
2024Nature Immunology0 citations
Semantic Scholar
DOP69 Glycans as an actor in the microbiome-immune response crosstalk
C. Rodrigues, J. Gaifem, M. Pereira, A. Lavelle +3 more
2023Journal of Crohn's & Colitis0 citations Open access
Semantic Scholar
Switch of Peripheral T Cells at Diagnosis SARS-CoV-2 Infection Drives a Glycan
S. Pinho, M. Abreu, R. Castro, Salomé +10 more
20210 citations
Semantic Scholar
Exploring NAD+ metabolism in host–pathogen interactions
Inês Mesquita, Patrícia Varela, Ana Belinha, J. Gaifem +4 more
2015Cellular and Molecular Life Sciences0 citations Open access
Semantic Scholar
Role Of In Endoplasmic Reticulum Stress Response In Sacccharoromyces cerevisiae
J. Gaifem
20110 citations
Semantic Scholar
The in ﬂ uence of surface modi ﬁ ed poly( L -lactic acid) ﬁ lms on the di ﬀ erentiation of human monocytes into macrophages †
C. R. Correia, J. Gaifem, Mariana B. Oliveira, Ricardo Silvestre +1 more
0 citations
Semantic Scholar

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