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L. Macvinish · SciRah

Researcher profile · Semantic Scholar

L. Macvinish

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L. Macvinish — researcher profile on SciRah

h-index: 25
Works: 45
Citations: 2,303

Most-cited papers

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
S. Hyde, D. Gill, C. F. Higgins, A. E. Trezíse +5 more
1993Nature447 citations
Semantic Scholar
Production of a severe cystic fibrosis mutation in mice by gene targeting
R. Ratcliff, M. Evans, A. Cuthbert, L. Macvinish +3 more
1993Nature Genetics281 citations
Semantic Scholar
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis
D. R. Gill, K. Southern, K. Mofford, T. Seddon +15 more
1997Gene Therapy254 citations Open access
Semantic Scholar
Generation and characterization of a ΔF508 cystic fibrosis mouse model
W. Colledge, B. Abella, K. Southern, R. Ratcliff +6 more
1995Nature Genetics169 citations
Semantic Scholar
Chloride secretion in response to guanylin in colonic epithelia from normal and transgenic cystic fibrosis mice
A. W. Cuthbert, M. E. Hickman, L. Macvinish, Mathew J. Evans +4 more
1994British Journal of Pharmacology102 citations Open access
Semantic Scholar
Importance of basolateral K+ conductance in maintaining Cl− secretion in murine nasal and colonic epithelia
L. Macvinish, M. E. Hickman, Dina A. H. Mufti, Hannah J. Durrington +1 more
1998Journal of Physiology90 citations Open access
Semantic Scholar
Complementation of null CF mice with a human CFTR YAC transgene
A. Manson, Ann E. O. Trezise, L. Macvinish, Kristin D. Kasschau +7 more
1997EMBO Journal82 citations Open access
Semantic Scholar
Generation and characterization of a delta F508 cystic fibrosis mouse model.
W. Colledge, B. Abella, K. Southern, R. Ratcliff +6 more
1995Nature Genetics70 citations
Semantic Scholar
Activation of Ca2+- and cAMP-sensitive K+ channels in murine colonic epithelia by 1-ethyl-2-benzimidazolone.
A. W. Cuthbert, M. E. Hickman, Peter Thorn, L. Macvinish
1999American Journal of Physiology - Cell Physiology50 citations
Semantic Scholar
Calcium‐and cyclic AMP‐dependent chloride secretion in human colonic epithelia
A. Cuthbert, C. Eglème, H. Greenwood, M. E. Hickman +2 more
1987British Journal of Pharmacology48 citations Open access
Semantic Scholar
Kinin effects on electrogenic ion transport in primary cultures of pig renal papillary collecting tubule cells.
A. Cuthbert, A. M. George, L. Macvinish
1985American Journal of Physiology46 citations
Semantic Scholar
Kinin effects on ion transport in monolayers of HCA‐7 cells, a line from a human colonic adenocarcinoma
A. W. Cuthbert, S. C. Kirkland, L. Macvinish
1985British Journal of Pharmacology45 citations Open access
Semantic Scholar
Chloride transporting capability of Calu‐3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR
L. Macvinish, G. Cope, A. Ropenga, A. W. Cuthbert
2007British Journal of Pharmacology36 citations Open access
Semantic Scholar
Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.
S. Buckley, S. Waddington, S. Jezzard, A. Bergau +5 more
2008Molecular Therapy34 citations Open access
Semantic Scholar
A second dose of a CFTR cDNA–liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea
C. Goddard, R. Ratcliff, J. R. Anderson, E. Glenn +9 more
1997Gene Therapy34 citations
Semantic Scholar
Normalization of ion transport in murine cystic fibrosis nasal epithelium using gene transfer.
L. Macvinish, C. Goddard, William H. Colledge, C. F. Higgins +2 more
1997American Journal of Physiology34 citations
Semantic Scholar
Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium.
L. Macvinish, Yuan Guo, A. Dixon, R. Murrell-Lagnado +1 more
2001Molecular Pharmacology31 citations Open access
Semantic Scholar
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis
A. W. Cuthbert, L. Macvinish, M. E. Hickman, R. Ratcliff +2 more
1994Pflügers Archiv30 citations
Semantic Scholar
Phenanthrolines – a new class of CFTR chloride channel openers
M. Duszyk, L. Macvinish, A. W. Cuthbert
2001British Journal of Pharmacology29 citations Open access
Semantic Scholar
4‐Chloro‐benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu‐3 human airway epithelial cells
A. J. Szkotak, M. Murthy, L. Macvinish, Marek Duszyk +1 more
2004British Journal of Pharmacology28 citations Open access
Semantic Scholar
Type 1 hypersensitivity reactions in reconstructed tissues using syngeneic cell types
A. Baird, A. Cuthbert, L. Macvinish
1987British Journal of Pharmacology27 citations Open access
Semantic Scholar
Cyclic AMP and Ca2+ interactions affecting epithelial chloride secretion in human cultured colonic epithelia
L. Macvinish, R. Pickles, A. W. Cuthbert
1993British Journal of Pharmacology26 citations Open access
Semantic Scholar
Bicarbonate‐dependent chloride secretion in Calu‐3 epithelia in response to 7,8‐benzoquinoline
A. Cuthbert, C. Supuran, L. Macvinish
2003Journal of Physiology25 citations
Semantic Scholar
Mechanisms of anion secretion in Calu‐3 human airway epithelial cells by 7,8‐benzoquinoline
A. W. Cuthbert, L. Macvinish
2003British Journal of Pharmacology25 citations Open access
Semantic Scholar
Kinin‐induced chloride permeability changes in colony 29 epithelia estimated from 125I− efflux and MEQ fluorescence
L. Macvinish, T. Reancharoen, A. W. Cuthbert
1993British Journal of Pharmacology25 citations Open access
Semantic Scholar
Formal analysis of electrogenic sodium, potassium, chloride and bicarbonate transport in mouse colon epithelium
A. W. Cuthbert, M. E. Hickman, L. Macvinish
1999British Journal of Pharmacology23 citations Open access
Semantic Scholar
4-Chlorobenzo[F]isoquinoline (CBIQ), a novel activator of CFTR and ΔF508 CFTR
M. Murthy, N. Pedemonte, L. Macvinish, Luis J. V. Galietta +1 more
200521 citations
Semantic Scholar
Activation of Ca 2 1 - and cAMP-sensitive K 1 channels in murine colonic epithelia by 1-ethyl-2-benzimidazolone
A. Cuthbert, M. E. Hickman, P. Thorn, L. Macvinish
199921 citations
Semantic Scholar
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10‐CFTR2.
L. Macvinish, D. Gill, S. Hyde, K. Mofford +7 more
1997Journal of Physiology21 citations Open access
Semantic Scholar
Chloride channels and anion fluxes in a human colonic epithelium (HCA‐7)
Robert M. Henderson, M. Ashford, L. Macvinish, A. W. Cuthbert
1992British Journal of Pharmacology19 citations Open access
Semantic Scholar
EBIO, an agent causing maintained epithelial chloride secretion by co-ordinate actions at both apical and basolateral membranes
L. Macvinish, J. Keogh, A. Cuthbert
2001Pflügers Archiv17 citations
Semantic Scholar
Antagonism of kinin effects on epithelia by Hoe 140: apparently competitive and non‐competitive interactions
A. W. Cuthbert, L. Macvinish, R. Pickles
1992British Journal of Pharmacology17 citations Open access
Semantic Scholar
The effect of implantation of trenbolone acetate and oestradiol-17β in wether lambs at two initial live weights on concentrations of steroidal residues and blood glucose, urea and thyroid hormones
L. Macvinish, H. Galbraith
198817 citations
Semantic Scholar
Selective in vivo transfection of murine biliary epithelia using polycation-enhanced adenovirus
Tristan R. McKay, L. Macvinish, B. Carpenter, M. Themis +6 more
2000Gene Therapy16 citations Open access
Semantic Scholar
Electrogenic bicarbonate secretion in mouse gallbladder.
L. Martin, M. E. Hickman, C. M. Curtis, L. Macvinish +1 more
1998American Journal of Physiology - Gastrointestinal and Liver Physiology15 citations Open access
Semantic Scholar
Restoration by intratracheal gene transfer of bicarbonate secretion in cystic fibrosis mouse gallbladder.
C. M. Curtis, L. Martin, C. F. Higgins, William H. Colledge +4 more
1998American Journal of Physiology - Gastrointestinal and Liver Physiology15 citations
Semantic Scholar
Kinin-stimulated chloride secretion in mouse colon requires the participation of CFTR chloride channels.
A. Cuthbert, M. J. Evans, W. Colledge, L. Macvinish +1 more
1994Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas8 citations
Semantic Scholar
4-Chlorobenzo[F]isoquinoline (CBIQ), a novel activator of CFTR and DeltaF508 CFTR.
M. Murthy, N. Pedemonte, L. Macvinish, Luis J. V. Galietta +1 more
2005European Journal of Pharmacology6 citations
Semantic Scholar
A note on the concentrations of steroidal residues in tissues of mature female sheep implanted with trenbolone acetate
L. Macvinish, H. Galbraith
19936 citations
Semantic Scholar
Diversity of kinin effects on transporting epithelia.
A. Cuthbert, L. Macvinish
1989Advances in Experimental Medicine and Biology6 citations
Semantic Scholar
Transporting epithelia as targets for kinin effects.
A. Cuthbert, L. Macvinish
1986Advances in Experimental Medicine and Biology5 citations
Semantic Scholar
Restoration by intratracheal gene transfer of bicarbonate secretion in cystic fibrosis mouse gallbladder
C. M. Curtis, L. Martin, C. F. Higgins, W. Colledge +4 more
19983 citations
Semantic Scholar
Electrogenic bicarbonate secretion in mouse gallbladder.
L. Martin, M. E. Hickman, C. M. Curtis, L. Macvinish +1 more
1998American Journal of Physiology1 citations Open access
Semantic Scholar
Chloride secretion inthetrachea ofnullcystic fibrosis mice: theeffects oftransfection withpTriallO-CFTR2
L. Macvinish, D. Gill, S. C. Hydet, K. Mofford +7 more
20110 citations
Semantic Scholar
Chloride conductance changes in cultured colonic epithelium induced by kinins.
A. Cuthbert, L. Macvinish, R. Henderson
1992Agents and actions. Supplements0 citations
Semantic Scholar

Frequent co-authors

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A. W. Cuthbert×22
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A. W. Cuthbert — researcher profile on SciRah
A. Cuthbert×19
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A. Cuthbert — researcher profile on SciRah
M. E. Hickman×12
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M. E. Hickman — researcher profile on SciRah
R. Ratcliff×10
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R. Ratcliff — researcher profile on SciRah

William H. Colledge

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William H. Colledge — researcher profile on SciRah

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W. Colledge — researcher profile on SciRah

C. F. Higgins×6

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C. F. Higgins — researcher profile on SciRah

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M. Evans — researcher profile on SciRah

Mathew J. Evans×5

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Mathew J. Evans — researcher profile on SciRah

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D. Gill — researcher profile on SciRah

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L. Martin — researcher profile on SciRah

C. M. Curtis×4

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C. M. Curtis — researcher profile on SciRah