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N. Vandeputte · SciRah

Researcher profile · Semantic Scholar

N. Vandeputte

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N. Vandeputte — researcher profile on SciRah

h-index: 16
Works: 33
Citations: 945

Most-cited papers

Shielding of the A1 Domain by the D′D3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein Ib-IX-V*
H. Ulrichts, M. Udvardy, P. Lenting, I. Pareyn +3 more
2006Journal of Biological Chemistry147 citations Open access
Semantic Scholar
Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus).
H. Feys, J. Roodt, N. Vandeputte, I. Pareyn +8 more
2010Blood122 citations Open access
Semantic Scholar
ADAMTS‐13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences
H. Feys, Fang Liu, N. Dong, I. Pareyn +6 more
2006Journal of Thrombosis and Haemostasis109 citations Open access
Semantic Scholar
Restoration of Plasma von Willebrand Factor Deficiency Is Sufficient to Correct Thrombus Formation After Gene Therapy for Severe von Willebrand Disease
S. D. De Meyer, N. Vandeputte, I. Pareyn, I. Petrus +5 more
2008Arteriosclerosis, Thrombosis and Vascular Biology77 citations Open access
Semantic Scholar
Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS13
L. Deforche, E. Roose, A. Vandenbulcke, N. Vandeputte +10 more
2015Journal of Thrombosis and Haemostasis73 citations Open access
Semantic Scholar
Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor and Plasminogen Activator Inhibitor-1 Reduces Ischemic Brain Damage in Mice
F. Denorme, T. Wyseure, M. Peeters, N. Vandeputte +5 more
2016Stroke61 citations Open access
Semantic Scholar
N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.
C. Tersteeg, J. Roodt, W. J. V. van Rensburg, C. Dekimpe +9 more
2017Blood57 citations Open access
Semantic Scholar
Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons.
H. Feys, J. Roodt, N. Vandeputte, I. Pareyn +6 more
2012Blood49 citations
Semantic Scholar
Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura
H. Feys, N. Vandeputte, R. Palla, F. Peyvandi +4 more
2010Journal of Thrombosis and Haemostasis44 citations Open access
Semantic Scholar
The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet‐decorated VWF strings in vivo
B. De Maeyer, S. D. De Meyer, H. Feys, I. Pareyn +3 more
2010Journal of Thrombosis and Haemostasis38 citations Open access
Semantic Scholar
Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura
E. Roose, G. Vidarsson, K. Kangro, O. Verhagen +16 more
2018Thrombosis and Haemostasis29 citations Open access
Semantic Scholar
High and long‐term von Willebrand factor expression after Sleeping Beauty transposon‐mediated gene therapy in a mouse model of severe von Willebrand disease
I. Portier, K. Vanhoorelbeke, S. Verhenne, I. Pareyn +8 more
2018Journal of Thrombosis and Haemostasis26 citations Open access
Semantic Scholar
Long-Term Prevention of Congenital Thrombotic Thrombocytopenic Purpura in ADAMTS13 Knockout Mice by Sleeping Beauty Transposon-Mediated Gene Therapy
S. Verhenne, N. Vandeputte, I. Pareyn, Z. Izsvák +4 more
2017Arteriosclerosis, Thrombosis and Vascular Biology19 citations Open access
Semantic Scholar
Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura
L. Deforche, C. Tersteeg, E. Roose, A. Vandenbulcke +7 more
2016PLoS ONE19 citations Open access
Semantic Scholar
Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura
E. Roose, C. Tersteeg, Ruth Demeersseman, A. Schelpe +9 more
2018TH Open18 citations Open access
Semantic Scholar
Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction*
Katleen Broos, Mieke Trekels, R. Jose, J. Demeulemeester +7 more
2012Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Shielding of the A 1 Domain by the D D 3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein
H. Ulrichts, M. Udvardy, P. Lenting, I. Pareyn +3 more
200613 citations
Semantic Scholar
von Willebrand factor in experimental malaria‐associated acute respiratory distress syndrome
Sirima Kraisin, S. Verhenne, Thao-Thy Pham, K. Martinod +6 more
2019Journal of Thrombosis and Haemostasis12 citations Open access
Semantic Scholar
Differences in von Willebrand factor function in type 2A von Willebrand disease and left ventricular assist device‐induced acquired von Willebrand syndrome
S. Deconinck, C. Tersteeg, E. Bailleul, L. Delrue +7 more
2018Research and Practice in Thrombosis and Haemostasis9 citations Open access
Semantic Scholar
Child‐onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13
A. Schelpe, C. Orlando, Bogac Ercig, Chloë Geeroms +10 more
2018European Journal of Haematology4 citations Open access
Semantic Scholar
von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice
I. Portier, K. Martinod, L. Desender, N. Vandeputte +3 more
2018Scientific Reports4 citations Open access
Semantic Scholar
Newly Developed ADAMTS13 Antigen Assay Reveals Marked Ethnic Differences and Depletion in Acquired Thrombotic Thrombocytopenic Purpura.
H. Feys, Fang Liu, N. Dong, I. Pareyn +5 more
20052 citations
Semantic Scholar
Acquired von Willebrand syndrome in patients on long-term left ventricular assist device support: Results of a Belgian center.
S. Deconinck, C. Tersteeg, E. Bailleul, L. Delrue +6 more
2019Thrombosis Research1 citations Open access
Semantic Scholar
Long-term gene therapy for thrombotic thrombocytopenic purpura using the 'Sleeping Beauty' transposon system
S. Verhenne, N. Vandeputte, I. Pareyn, Z. Izsvák +4 more
20151 citations
Semantic Scholar
RESTORATION OF VON WILLEBRAND FACTOR FUNCTION IN A MURINE MODEL OF SEVERE VON WILLEBRAND DISEASE AFTER LIVER SPECIFIC GENE TRANSFER
S. Meyer, M. Chuah, T. VandenDriessche, N. Vandeputte +4 more
20071 citations
Semantic Scholar
Anti-CUB1 or Anti-Spacer Antibodies That Increase ADAMTS13 Activity Act By Allosterically Enhancing Metalloprotease Domain Function
A. Schelpe, A. Petri, N. Vandeputte, H. Deckmyn +3 more
2018Blood0 citations Open access
Semantic Scholar
Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology
E. Roose, A. Schelpe, E. Tellier, György Sinkovits +17 more
2018Blood0 citations Open access
Semantic Scholar
P5119Differences in VWF activity in von willebrand disease type 2A patients versus LVAD patients with the acquired von willebrand syndrome
S. Deconinck, C. Terseeg, E. Bailleul, L. Delrue +5 more
2018European Heart Journal0 citations
Semantic Scholar
P3277Distinct differences in laboratory findings of patients with von Willebrand disease type 2A versus patients with LVAD-induced acquired von Willebrand syndrome
S. Deconinck, C. Tersteeg, E. Bailleul, L. Delrue +7 more
20170 citations Open access
Semantic Scholar
ADAMTS13-induced unfolding of the von Willebrand factor A2 domain
L. Deforche, H. Feys, K. De Ceunynck, A. Vandenbulcke +10 more
20150 citations
Semantic Scholar
Inhibition of TAFI and PAI-1 protects mice from cerebral ischemia/reperfusion injury
F. Denorme, T. Wyseure, M. Peeters, N. Vandeputte +5 more
20150 citations
Semantic Scholar
The antithrombotic effect of the fucoidan of Lessonia vadosa: a strong inhibitior of the platelet GPIb receptor - von Willebrand factor interaction
Katleen Broos, W. De Borggraeve, A. Vandenbulcke, N. Vandeputte +5 more
20110 citations
Semantic Scholar
Distinct differences in laboratory findings of patients with von Willebrand disease type 2A versus patients with LVAD-induced acquired von Willebrand syndrome
S. Deconinck, C. Tersteeg, E. Bailleul, L. Delrue +38 more
0 citations
Semantic Scholar

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