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T. Eckle · SciRah

Researcher profile · Semantic Scholar

T. Eckle

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T. Eckle — researcher profile on SciRah

h-index: 41
Works: 102
Citations: 11K

Most-cited papers

Ischemia and reperfusion—from mechanism to translation
H. Eltzschig, T. Eckle
2011Nature Medicine3,305 citations Open access
Semantic Scholar
Physiological roles for ecto-5’-nucleotidase (CD73)
S. Colgan, H. Eltzschig, T. Eckle, L. Thompson
2006Purinergic Signalling Purinergic Signalling535 citations Open access
Semantic Scholar
Myocardial ischemia reperfusion injury - from basic science to clinical bedside
Anja Frank, Megan Bonney, Stephanie Bonney, L. Weitzel +2 more
2012Seminars in Cardiothoracic and Vascular Anesthesia526 citations Open access
Semantic Scholar
Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A2B Adenosine Receptors
T. Eckle, T. Krahn, A. Grenz, David Köhler +7 more
2007Circulation472 citations
Semantic Scholar
Hypoxia-Inducible Factor-1 Is Central to Cardioprotection: A New Paradigm for Ischemic Preconditioning
T. Eckle, David Köhler, R. Lehmann, K. El Kasmi +1 more
2008Circulation416 citations Open access
Semantic Scholar
ATP Release From Activated Neutrophils Occurs via Connexin 43 and Modulates Adenosine-Dependent Endothelial Cell Function
H. Eltzschig, T. Eckle, A. Mager, Natalie Küper +6 more
2006Circulation Research360 citations Open access
Semantic Scholar
A2B adenosine receptor dampens hypoxia-induced vascular leak.
T. Eckle, M. Faigle, A. Grenz, Stefanie Laucher +2 more
2008Blood322 citations Open access
Semantic Scholar
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch critical for myocardial adaptation to ischemia
T. Eckle, Katherine Hartmann, Stephanie Bonney, Susan A. Reithel +9 more
2012Nature Medicine318 citations Open access
Semantic Scholar
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice.
T. Eckle, A. Grenz, Stefanie Laucher, H. Eltzschig
2008Journal of Clinical Investigation301 citations Open access
Semantic Scholar
Identification of Ectonucleotidases CD39 and CD73 in Innate Protection during Acute Lung Injury1
T. Eckle, L. Füllbier, M. Wehrmann, Joseph Khoury +4 more
2007Journal of Immunology284 citations Open access
Semantic Scholar
The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia
A. Grenz, H. Osswald, T. Eckle, Dan Yang +5 more
2008PLoS Medicine232 citations Open access
Semantic Scholar
CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia/Reperfusion Injury
David Köhler, T. Eckle, M. Faigle, A. Grenz +6 more
2007Circulation221 citations Open access
Semantic Scholar
Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury
Ulrich Schingnitz, Katherine Hartmann, C. Macmanus, T. Eckle +3 more
2010Journal of Immunology187 citations Open access
Semantic Scholar
Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia.
A. Grenz, Hua Zhang, T. Eckle, M. Mittelbronn +6 more
2007Journal of the American Society of Nephrology182 citations
Semantic Scholar
HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium
T. Eckle, Kelley S. Brodsky, Megan Bonney, Thomas A. Packard +6 more
2013PLoS Biology170 citations Open access
Semantic Scholar
Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice.
T. Eckle, A. Grenz, David Köhler, A. Redel +5 more
2006American Journal of Physiology. Heart and Circulatory Physiology131 citations
Semantic Scholar
Role of extracellular adenosine in acute lung injury.
T. Eckle, M. Koeppen, H. Eltzschig
2009Physiology125 citations
Semantic Scholar
Metabolomic Analysis of Key Central Carbon Metabolism Carboxylic Acids as Their 3-Nitrophenylhydrazones by UPLC/ESI-MS
Jun Han, S. Gagnon, T. Eckle, Christoph H. Borchers
2013Electrophoresis122 citations Open access
Semantic Scholar
Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury
M. Koeppen, Jae W. Lee, S. Seo, Kelley S. Brodsky +5 more
2018Nature Communications113 citations Open access
Semantic Scholar
Attenuating myocardial ischemia by targeting A2B adenosine receptors
H. Eltzschig, Stephanie Bonney, T. Eckle
2013Trends in Molecular Medicine112 citations Open access
Semantic Scholar
Identification of hypoxia-inducible factor HIF1A as transcriptional regulator of the A2B adenosine receptor during acute lung injury
T. Eckle, E. Kewley, Kelley S. Brodsky, Eunyoung Tak +7 more
2014Journal of Immunology109 citations Open access
Semantic Scholar
Nucleotide metabolism and cell-cell interactions.
H. Eltzschig, Thomas Weissmuller, A. Mager, T. Eckle
2006Methods in molecular biology104 citations
Semantic Scholar
Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury
T. Eckle, Kelly Hughes, Heidi Ehrentraut, Kelley S. Brodsky +7 more
2013The FASEB Journal99 citations Open access
Semantic Scholar
Selective Deletion of the A1 Adenosine Receptor Abolishes Heart-Rate Slowing Effects of Intravascular Adenosine In Vivo
M. Koeppen, T. Eckle, H. Eltzschig
2009PLoS ONE89 citations Open access
Semantic Scholar
Contribution of E‐NTPDasel (CD39) to renal protection from ischemia‐reperfusion injury
A. Grenz, Hua Zhang, M. Hermes, T. Eckle +6 more
2007The FASEB Journal89 citations
Semantic Scholar
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury
A. Grenz, Hua Zhang, M. Hermes, T. Eckle +6 more
200787 citations
Semantic Scholar
Cardiac Per2 Functions as Novel Link between Fatty Acid Metabolism and Myocardial Inflammation during Ischemia and Reperfusion Injury of the Heart
Stephanie Bonney, Douglas J. Kominsky, Kelley S. Brodsky, H. Eltzschig +2 more
2013PLoS ONE78 citations Open access
Semantic Scholar
Interplay of hypoxia and A2B adenosine receptors in tissue protection.
M. Koeppen, T. Eckle, H. Eltzschig
2011Advances in Pharmacology73 citations
Semantic Scholar
Ganciclovir-resistant cytomegalovirus disease after allogeneic stem cell transplantation: pitfalls of phenotypic diagnosis by in vitro selection of an UL97 mutant strain.
K. Hamprecht, T. Eckle, L. Prix, C. Faul +2 more
2003Journal of Infectious Diseases73 citations
Semantic Scholar
Health implications of disrupted circadian rhythms and the potential for daylight as therapy
Jason C. Brainard, Merit Gobel, Benjamin K. Scott, M. Koeppen +1 more
2015Anesthesiology70 citations Open access
Semantic Scholar
Circadian Rhythms in Anesthesia and Critical Care Medicine: Potential importance of circadian disruptions
Jason C. Brainard, Merit Gobel, K. Bartels, Benjamin K. Scott +2 more
2014Seminars in Cardiothoracic and Vascular Anesthesia63 citations Open access
Semantic Scholar
Direct Treatment of Mouse or Human Blood With Soluble 5′-Nucleotidase Inhibits Platelet Aggregation
Melanie L. Hart, David Köhler, T. Eckle, D. Kloor +2 more
2008Arteriosclerosis, Thrombosis and Vascular Biology61 citations
Semantic Scholar
Impact of Ischemia and Reperfusion Times on Myocardial Infarct Size in Mice In Vivo
A. Redel, V. Jazbutyte, Thorsten M. Smul, M. Lange +4 more
2008Experimental biology and medicine59 citations
Semantic Scholar
The Hypoxia-Inflammation Link and Potential Drug Targets
M. Koeppen, T. Eckle, H. Eltzschig
2011Current Opinion in Anaesthesiology58 citations Open access
Semantic Scholar
Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium
Y. Oyama, C. M. Bartman, Stephanie Bonney, J. S. Lee +8 more
2019bioRxiv53 citations Open access
Semantic Scholar
Adora2b Signaling on Bone Marrow Derived Cells Dampens Myocardial Ischemia-Reperfusion Injury
M. Koeppen, P. Harter, Stephanie Bonney, Megan Bonney +4 more
2012Anesthesiology50 citations Open access
Semantic Scholar
Analysis of Selected Sugars and Sugar Phosphates in Mouse Heart Tissue by Reductive Amination and Liquid Chromatography-Electrospray Ionization Mass Spectrometry
Jun Han, Vera Tschernutter, Jun-Cong Yang, T. Eckle +1 more
2013Analytical Chemistry48 citations Open access
Semantic Scholar
Upregulation of the Water Channel Aquaporin-4 as a Potential Cause of Postischemic Cell Swelling in a Murine Model of Myocardial Infarction
A. Warth, T. Eckle, David Köhler, M. Faigle +4 more
2007The Cardiology48 citations
Semantic Scholar
Intense light-elicited upregulation of miR-21 facilitates glycolysis and cardioprotection through Per2-dependent mechanisms
C. M. Bartman, Y. Oyama, Kelley S. Brodsky, L. Khailová +3 more
2017PLoS ONE47 citations Open access
Semantic Scholar
Differential tissue-specific function of the Adora2b in cardio-protection
S. Seo, M. Koeppen, Stephanie Bonney, Merit Gobel +7 more
2015Journal of Immunology37 citations Open access
Semantic Scholar
The PER2 enhancer nobiletin as novel therapy in murine models of circadian disruption resembling delirium
J. Gile, Benjamin K. Scott, T. Eckle
2018Critical Care Medicine35 citations Open access
Semantic Scholar
Circadian MicroRNAs in Cardioprotection
Y. Oyama, C. M. Bartman, J. Gile, T. Eckle
2017Current pharmaceutical design35 citations Open access
Semantic Scholar
Cardiac Period 2 in myocardial ischemia: Clinical implications of a light dependent protein
Stephanie Bonney, Kelly Hughes, P. Harter, M. Mittelbronn +2 more
2013International Journal of Biochemistry and Cell Biology34 citations Open access
Semantic Scholar
Use of a hanging-weight system for isolated renal artery occlusion during ischemic preconditioning in mice.
A. Grenz, T. Eckle, Hua Zhang, D. Huang +5 more
2007AJP - Renal Physiology34 citations
Semantic Scholar
Usefulness of pressure-controlled ventilation at high inspiratory pressures to induce acute lung injury in mice.
T. Eckle, L. Füllbier, A. Grenz, H. Eltzschig
2008American Journal of Physiology - Lung cellular and Molecular Physiology33 citations
Semantic Scholar
Circadian-Hypoxia Link and its Potential for Treatment of Cardiovascular Disease
C. M. Bartman, T. Eckle
2019Current pharmaceutical design31 citations Open access
Semantic Scholar
Transcription-independent induction of ERBB1 through hypoxia-inducible factor HIF2A provides cardio-protection during ischemia and reperfusion
Jae W. Lee, M. Koeppen, S. Seo, J. Bowser +8 more
2019Anesthesiology30 citations Open access
Semantic Scholar
Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia.
A. Grenz, Hua Zhang, J. Weingart, Simone von Wietersheim +8 more
2007AJP - Renal Physiology30 citations
Semantic Scholar
The circadian PER2 enhancer Nobiletin reverses the deleterious effects of midazolam in myocardial ischemia and reperfusion injury
Y. Oyama, C. M. Bartman, J. Gile, D. Sehrt +1 more
2018Current pharmaceutical design26 citations Open access
Semantic Scholar
CD 39 / Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia / Reperfusion Injury
David Köhler, T. Eckle, M. Faigle, A. Grenz +6 more
200726 citations
Semantic Scholar

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H. Eltzschig×36
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H. Eltzschig — researcher profile on SciRah
A. Grenz×13
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M. Koeppen×12
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M. Mittelbronn×10
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Stephanie Bonney

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