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K. Dezaki · SciRah

Researcher profile · Semantic Scholar

K. Dezaki

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K. Dezaki — researcher profile on SciRah

h-index: 30
Works: 99
Citations: 4,703

Most-cited papers

Ghrelin is present in pancreatic α-cells of humans and rats and stimulates insulin secretion
Y. Date, M. Nakazato, S. Hashiguchi, K. Dezaki +8 more
2002577 citations
Semantic Scholar
Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)
Y. Okada, E. Maeno, Takahiro Shimizu, K. Dezaki +2 more
2001Journal of Physiology543 citations Open access
Semantic Scholar
Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents.
K. Dezaki, H. Hosoda, M. Kakei, S. Hashiguchi +3 more
2004Diabetes377 citations
Semantic Scholar
Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
Y. Maejima, Udval Sedbazar, Shigetomo Suyama, Daisuke Kohno +17 more
2009Cell Metabolism324 citations Open access
Semantic Scholar
Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion.
Y. Date, M. Nakazato, S. Hashiguchi, K. Dezaki +8 more
2002Diabetes297 citations
Semantic Scholar
Blockade of Pancreatic Islet–Derived Ghrelin Enhances Insulin Secretion to Prevent High-Fat Diet–Induced Glucose Intolerance
K. Dezaki, H. Sone, M. Koizumi, M. Nakata +5 more
2006Diabetes252 citations Open access
Semantic Scholar
Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice
Kunitoshi Uchida, K. Dezaki, B. Damdindorj, H. Inada +5 more
2010Diabetes184 citations Open access
Semantic Scholar
GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose
Yusaku Iwasaki, Mio Sendo, K. Dezaki, T. Hira +14 more
2018Nature Communications175 citations Open access
Semantic Scholar
Ghrelin Uses Gαi2 and Activates Voltage-Dependent K+ Channels to Attenuate Glucose-Induced Ca2+ Signaling and Insulin Release in Islet β-Cells
K. Dezaki, M. Kakei, T. Yada
2007Diabetes173 citations
Semantic Scholar
Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis.
K. Dezaki, H. Sone, T. Yada
2008Pharmacology and Therapeutics159 citations
Semantic Scholar
Stressor-responsive central nesfatin-1 activates corticotropin-releasing hormone, noradrenaline and serotonin neurons and evokes hypothalamic-pituitary-adrenal axis
Natsu Yoshida, Y. Maejima, Udval Sedbazar, A. Ando +11 more
2010Aging139 citations Open access
Semantic Scholar
NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia–Reperfusion Injury Independently of Inflammasomes
Yoshiyuki Inoue, K. Shirasuna, Hiroaki Kimura, Fumitake Usui +14 more
2014Journal of Immunology130 citations Open access
Semantic Scholar
Ghrelin regulates insulin release and glycemia: physiological role and therapeutic potential.
T. Yada, K. Dezaki, H. Sone, M. Koizumi +3 more
2008Current Diabetes Reviews104 citations
Semantic Scholar
Involvement of thermosensitive TRP channels in energy metabolism
Kunitoshi Uchida, K. Dezaki, T. Yoneshiro, Tatsuo Watanabe +5 more
2017Journal of Physiological Sciences85 citations Open access
Semantic Scholar
Potentiation of Glucose-stimulated Insulin Secretion by the GPR40–PLC–TRPC Pathway in Pancreatic β-Cells
H. Yamada, Masashi Yoshida, K. Ito, K. Dezaki +3 more
2016Scientific Reports77 citations Open access
Semantic Scholar
Involvement of cAMP/EPAC/TRPM2 Activation in Glucose- and Incretin-Induced Insulin Secretion
Masashi Yosida, K. Dezaki, Kunitoshi Uchida, Shiho Kodera +11 more
2014Diabetes67 citations Open access
Semantic Scholar
Receptor-mediated facilitation of cell volume regulation by swelling-induced ATP release in human epithelial cells.
K. Dezaki, T. Tsumura, E. Maeno, Yasunobu Okada
2000The Japanese Journal of Physiology67 citations Open access
Semantic Scholar
Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet β-Cells
K. Dezaki, B. Damdindorj, H. Sone, O. Dyachok +6 more
2011Diabetes61 citations Open access
Semantic Scholar
The β-cell GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin
Tomoyuki Kurashina, K. Dezaki, Masashi Yoshida, Rauza Sukma Rita +7 more
2015Scientific Reports56 citations Open access
Semantic Scholar
Ghrelin function in insulin release and glucose metabolism.
K. Dezaki
2013Endocrine Development52 citations
Semantic Scholar
Immunohistochemical localization of neuronal nicotinic receptor subtypes at the pre- and postjunctional sites in mouse diaphragm muscle.
H. Tsuneki, I. Kimura, K. Dezaki, M. Kimura +2 more
1995Neuroscience Letters46 citations
Semantic Scholar
Ninjin-yoeito activates ghrelin-responsive and unresponsive NPY neurons in the arcuate nucleus and counteracts cisplatin-induced anorexia.
C. Goswami, K. Dezaki, Lei Wang, A. Inui +2 more
2019Neuropeptides41 citations
Semantic Scholar
Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca2+ Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity
Yusaku Iwasaki, K. Shimomura, Daisuke Kohno, K. Dezaki +7 more
2013PLoS ONE36 citations Open access
Semantic Scholar
Exogenous and endogenous ghrelin counteracts GLP‐1 action to stimulate cAMP signaling and insulin secretion in islet β‐cells
B. Damdindorj, K. Dezaki, Tomoyuki Kurashina, H. Sone +3 more
2012FEBS Letters36 citations
Semantic Scholar
Inhibition of Y1 receptor signaling improves islet transplant outcome
Kim Loh, Yan-Chuan Shi, S. Walters, M. Bensellam +14 more
2017Nature Communications34 citations Open access
Semantic Scholar
Endogenous α2A-Adrenoceptor–Operated Sympathoadrenergic Tones Attenuate Insulin Secretion via cAMP/TRPM2 Signaling
K. Ito, K. Dezaki, Masashi Yoshida, H. Yamada +9 more
2016Diabetes34 citations
Semantic Scholar
Early-phase occurrence of K+ and Cl− efflux in addition to Ca2+ mobilization is a prerequisite to apoptosis in HeLa cells
K. Dezaki, E. Maeno, Kaori Sato, T. Akita +1 more
2012Apoptosis33 citations
Semantic Scholar
β-Cell–Specific Deletion of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) Reductase Causes Overt Diabetes due to Reduction of β-Cell Mass and Impaired Insulin Secretion
Ada Admin, Shoko Takei, Shuichi Nagashima, Akihito Takei +14 more
2020Diabetes32 citations Open access
Semantic Scholar
Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons.
Hideharu Kurita, Kai Y. Xu, Y. Maejima, M. Nakata +10 more
2015American Journal of Physiology. Endocrinology and Metabolism32 citations
Semantic Scholar
Flux pinning properties of ErBa2Cu3Oy thin films with BaZrO3 nanorods
M. Haruta, T. Fujiyoshi, T. Sueyoshi, K. Dezaki +8 more
200631 citations
Semantic Scholar
Ghrelin counteracts salt-induced hypertension via promoting diuresis and renal nitric oxide production in Dahl rats.
Hirotaka Aoki, M. Nakata, K. Dezaki, Ming-You Lu +5 more
2013Endocrine journal28 citations Open access
Semantic Scholar
A novel mechanism of imeglimin‐mediated insulin secretion via the cADPR‐TRP channel pathway
Shunsuke Funazaki, Masashi Yoshida, H. Yamada, M. Kakei +4 more
2021Journal of Diabetes Investigation27 citations Open access
Semantic Scholar
Regulation of voltage‐gated K+ channels by glucose metabolism in pancreatic β‐cells
Masashi Yoshida, K. Dezaki, S. Yamato, A. Aoki +7 more
2009FEBS Letters27 citations
Semantic Scholar
Inhibition of insulin secretion from rat pancreatic islets by dexmedetomidine and medetomidine, two sedatives frequently used in clinical settings.
Shiho Kodera, Masashi Yoshida, K. Dezaki, T. Yada +3 more
2013Endocrine journal26 citations Open access
Semantic Scholar
Neuropeptide W in the rat pancreas: potentiation of glucose-induced insulin release and Ca2+ influx through L-type Ca2+ channels in beta-cells and localization in islets.
K. Dezaki, H. Kageyama, M. Seki, S. Shioda +1 more
2008Regulatory Peptides20 citations
Semantic Scholar
Enhancement by calcitonin gene‐related peptide of nicotinic receptor‐operated noncontractile Ca2+ mobilization at the mouse neuromuscular junction
I. Kimura, H. Tsuneki, K. Dezaki, M. Kimura
1993British Journal of Pharmacology20 citations Open access
Semantic Scholar
Serum ghrelin levels partially recover with the recovery of appetite and food intake after total gastrectomy
M. Koizumi, Y. Hosoya, K. Dezaki, T. Yada +6 more
2014Surgery today (Print)18 citations
Semantic Scholar
Islet β-cell ghrelin signaling for inhibition of insulin secretion.
K. Dezaki, T. Yada
2012Methods in Enzymology18 citations
Semantic Scholar
Muscle mass evaluation using psoas muscle mass index by computed tomography imaging in hemodialysis patients.
K. Ito, S. Ookawara, Sojiro Imai, Hideo Kakuda +18 more
2021Clinical Nutrition ESPEN17 citations
Semantic Scholar
Postoperative weight loss does not resolve after esophagectomy despite normal serum ghrelin levels.
M. Koizumi, Y. Hosoya, K. Dezaki, T. Yada +6 more
2011Annals of Thoracic Surgery17 citations
Semantic Scholar
Postsynaptic nicotinic receptor desensitized by non‐contractile Ca2+ mobilization via protein kinase‐C activation at the mouse neuromuscular junction
I. Kimura, K. Dezaki, H. Tsuneki, M. Kimura
1995British Journal of Pharmacology17 citations Open access
Semantic Scholar
Oleic Acid Glucose-Independently Stimulates Glucagon Secretion by Increasing Cytoplasmic Ca2+ via Endoplasmic Reticulum Ca2+ Release and Ca2+ Influx in the Rat Islet α-Cells
K. Fujiwara, F. Maekawa, K. Dezaki, M. Nakata +2 more
200716 citations
Semantic Scholar
Glucose and GTP-binding protein-coupled receptor cooperatively regulate transient receptor potential-channels to stimulate insulin secretion [Review].
M. Kakei, Masashi Yoshida, K. Dezaki, K. Ito +5 more
2016Endocrine journal15 citations Open access
Semantic Scholar
Total gastrectomy-induced reductions in food intake and weight are counteracted by rikkunshito by attenuating glucagon-like peptide-1 elevation in rats.
M. Taguchi, K. Dezaki, M. Koizumi, K. Kurashina +4 more
2016Surgery14 citations
Semantic Scholar
Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic beta-cells.
Masashi Yoshida, M. Nakata, S. Yamato, K. Dezaki +5 more
2010Biochemical and Biophysical Research Communications - BBRC14 citations
Semantic Scholar
GLP-1 and ghrelin inversely regulate insulin secretion and action in pancreatic islets, vagal afferents and hypothalamus for controlling glycemia and feeding.
Toshihiko Yada, K. Dezaki, Yusaku Iwasaki
2025American Journal of Physiology - Cell Physiology13 citations
Semantic Scholar
Ninjin'yoeito Targets Distinct Ca2+ Channels to Activate Ghrelin-Responsive vs. Unresponsive NPY Neurons in the Arcuate Nucleus
C. Goswami, K. Dezaki, Lei Wang, A. Inui +2 more
2020Frontiers in Nutrition13 citations Open access
Semantic Scholar
A new experimental model of ATP-sensitive K⁺ channel-independent insulinotropic action of glucose: a permissive role of cAMP for triggering of insulin release from rat pancreatic β-cells.
M. Takei, K. Dezaki, Hiroaki Ishii, S. Nishio +4 more
2013Endocrine journal13 citations Open access
Semantic Scholar
Status of ghrelin as an islet hormone and paracrine/autocrine regulator of insulin secretion.
K. Dezaki, T. Yada
2021Peptides12 citations
Semantic Scholar
Partial blockade of Kv2.1 channel potentiates GLP-1's insulinotropic effects in islets and reduces its dose required for improving glucose tolerance in type 2 diabetic male mice.
Rauza Sukma Rita, K. Dezaki, Tomoyuki Kurashina, M. Kakei +1 more
2015Endocrinology12 citations
Semantic Scholar

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T. Yada×38
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T. Yada — researcher profile on SciRah
M. Kakei×19
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M. Kakei — researcher profile on SciRah
M. Nakata×12
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Masashi Yoshida×9
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H. Hosoda — researcher profile on SciRah

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K. Kangawa — researcher profile on SciRah

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K. Ito — researcher profile on SciRah

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M. Koizumi — researcher profile on SciRah

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B. Damdindorj — researcher profile on SciRah

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Tomoyuki Kurashina — researcher profile on SciRah

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H. Yamada — researcher profile on SciRah