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M. Beullens · SciRah

Researcher profile · Semantic Scholar

M. Beullens

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M. Beullens — researcher profile on SciRah

h-index: 50
Works: 140
Citations: 7,103

Most-cited papers

The extended PP1 toolkit: designed to create specificity
M. Bollen, W. Peti, M. J. Ragusa, M. Beullens
2010TIBS -Trends in Biochemical Sciences. Regular ed509 citations Open access
Semantic Scholar
Docking motif-guided mapping of the interactome of protein phosphatase-1.
A. Hendrickx, M. Beullens, H. Ceulemans, Tom den Abt +4 more
2009Chemistry and Biology331 citations Open access
Semantic Scholar
The PP1 binding code: a molecular‐lego strategy that governs specificity
Ewald Heroes, Bart Lesage, Janina Görnemann, M. Beullens +2 more
2013The FEBS Journal318 citations
Semantic Scholar
Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory
K. Koshibu, J. Gräff, M. Beullens, F. Heitz +5 more
2009Journal of Neuroscience205 citations Open access
Semantic Scholar
MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells
Kaushal Joshi, Y. Banasavadi-Siddegowda, X. Mo, Sung-Hak Kim +9 more
2013Stem Cells199 citations Open access
Semantic Scholar
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.
L. Bultot, B. Guigas, Alexander von Wilamowitz-Moellendorff, L. Maisin +9 more
2012Biochemical Journal117 citations
Semantic Scholar
The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2
Lijs Beke, Mieke Nuytten, A. Van Eynde, M. Beullens +1 more
2007Oncogene117 citations
Semantic Scholar
Substrate Specificity and Activity Regulation of Protein Kinase MELK*
M. Beullens, Sadia Vancauwenbergh, N. Morrice, R. Derua +3 more
2005Journal of Biological Chemistry114 citations Open access
Semantic Scholar
MELK—a conserved kinase: functions, signaling, cancer, and controversy
Ranjit Ganguly, Ahmed Mohyeldin, J. Thiel, H. Kornblum +2 more
2015Clinical and Translational Medicine107 citations Open access
Semantic Scholar
Split‐BioID: a proximity biotinylation assay for dimerization‐dependent protein interactions
S. De Munter, Janina Görnemann, R. Derua, Bart Lesage +6 more
2017FEBS Letters106 citations Open access
Semantic Scholar
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
Evy Lobbestael, Jing Zhao, I. Rudenko, Aleksandra Beylina +8 more
2013Biochemical Journal98 citations Open access
Semantic Scholar
Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man.
J. Qian, M. Beullens, Bart Lesage, M. Bollen
2013Current Biology91 citations Open access
Semantic Scholar
Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells.
Dirk Vander Mierde, D. Scheuner, R. Quintens, Rupali Patel +6 more
2007Endocrinology86 citations Open access
Semantic Scholar
The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 holoenzyme
N. O'Connell, S. Nichols, Ewald Heroes, M. Beullens +3 more
2012Structure82 citations Open access
Semantic Scholar
The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing
Mieke Nuytten, Lijs Beke, A. Van Eynde, H. Ceulemans +4 more
2008Oncogene82 citations Open access
Semantic Scholar
The PP1‐R6 protein phosphatase holoenzyme is involved in the glucose‐induced dephosphorylation and inactivation of AMP‐activated protein kinase, a key regulator of insulin secretion, in MIN6 β cells
Luisa García-Haro, M. García-Gimeno, D. Neumann, M. Beullens +2 more
2010The FASEB Journal81 citations Open access
Semantic Scholar
A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3.
Bart Lesage, M. Beullens, Leda Pedelini, M. García-Gimeno +3 more
2007Biochemistry75 citations Open access
Semantic Scholar
MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells
Lijs Beke, Cenk Kığ, J. T. Linders, Shannah Boens +13 more
2015Bioscience Reports72 citations Open access
Semantic Scholar
Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells
J. Chatterjee, M. Beullens, R. Sukackaitė, J. Qian +4 more
2012Angewandte Chemie72 citations Open access
Semantic Scholar
Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch
J. Qian, M. Beullens, Jin Huang, S. De Munter +2 more
2015Nature Communications68 citations Open access
Semantic Scholar
False-positive detection of recombinant human erythropoietin in urine following strenuous physical exercise.
M. Beullens, J. Delanghe, M. Bollen
2006Blood67 citations
Semantic Scholar
Nuclear Targeting of Protein Phosphatase-1 by HIV-1 Tat Protein*
T. Ammosova, M. Jerebtsova, M. Beullens, Bart Lesage +6 more
2005Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Y65C Missense Mutation in the WW Domain of the Golabi-Ito-Hall Syndrome Protein PQBP1 Affects Its Binding Activity and Deregulates Pre-mRNA Splicing*
Victor E. Tapia, E. Nicolaescu, Caleb B. McDonald, V. Musi +14 more
2010Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis.
Xiao-Jiang Quan, Li-Qun Yuan, L. Tiberi, Annelies Claeys +12 more
2016Cell64 citations Open access
Semantic Scholar
Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)*
N. Tanuma, Sei-Eun Kim, M. Beullens, Y. Tsubaki +9 more
2008Journal of Biological Chemistry62 citations Open access
Semantic Scholar
An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint.
J. Qian, M. García-Gimeno, M. Beullens, Maria Giulia Manzione +6 more
2017Molecules and Cells59 citations Open access
Semantic Scholar
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.
P. Vangheluwe, M. Tjwa, A. van den Bergh, W. Louch +8 more
2006Journal of Molecular and Cellular Cardiology55 citations
Semantic Scholar
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma
L. Vandenberk, Abhishek D Garg, Tina Verschuere, C. Koks +5 more
2015Oncoimmunology53 citations Open access
Semantic Scholar
Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor.
B. Devogelaere, M. Beullens, E. Sammels, R. Derua +6 more
2007Biochemical Journal53 citations Open access
Semantic Scholar
Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics
Mónica Ferreira, M. Beullens, M. Bollen, A. Van Eynde
2018Biochimica et biophysica acta. Molecular cell research51 citations Open access
Semantic Scholar
Testing for recombinant erythropoietin
J. Delanghe, M. Bollen, M. Beullens
2008American journal of hematology/oncology49 citations Open access
Semantic Scholar
CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90
Denitra Breuer, A. Kotelkin, T. Ammosova, N. Kumari +8 more
2012Retrovirology48 citations Open access
Semantic Scholar
Expression of a Protein Phosphatase 1 Inhibitor, cdNIPP1, Increases CDK9 Threonine 186 Phosphorylation and Inhibits HIV-1 Transcription*
T. Ammosova, Venkat R. K. Yedavalli, Xiao-Mei Niu, M. Jerebtsova +5 more
2010Journal of Biological Chemistry48 citations Open access
Semantic Scholar
The transcription factor ERG recruits CCR4–NOT to control mRNA decay and mitotic progression
Xavier Rambout, Cécile Detiffe, Jonathan Bruyr, Emeline Mariavelle +18 more
2016Nature Structural &Molecular Biology46 citations Open access
Semantic Scholar
NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes
Nikki Minnebo, Janina Görnemann, N. O'Connell, Nele Van Dessel +7 more
2012Nucleic Acids Research46 citations Open access
Semantic Scholar
Characterization of the Condensin Component Cnap1 and Protein Kinase Melk as Novel E2F Target Genes Down-regulated by 1,25-Dihydroxyvitamin D3*
L. Verlinden, G. Eelen, Ine Beullens, M. Van Camp +12 more
2005Journal of Biological Chemistry46 citations Open access
Semantic Scholar
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Dan Wu, Veerle De Wever, R. Derua, C. Winkler +3 more
2018Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Structure and Function of the Two Tandem WW Domains of the Pre-mRNA Splicing Factor FBP21 (Formin-binding Protein 21)*
Xiaojuan Huang, M. Beullens, Jia-Hai Zhang, Yi Zhou +6 more
2009Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175
T. Ammosova, Yuri Obukhov, A. Kotelkin, Denitra Breuer +4 more
2011PLoS ONE42 citations Open access
Semantic Scholar
Inhibitor‐3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore‐bound protein phosphatase‐1
Annika Eiteneuer, Jonas Seiler, Matthias Weith, M. Beullens +5 more
2014EMBO Journal38 citations Open access
Semantic Scholar
The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets
Nele Van Dessel, Lijs Beke, Janina Görnemann, Nikki Minnebo +5 more
2010Nucleic Acids Research38 citations Open access
Semantic Scholar
The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth
C. Winkler, S. De Munter, Nele Van Dessel, Bart Lesage +5 more
2015Journal of Cell Science35 citations Open access
Semantic Scholar
Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer
K. Litovkin, S. Joniau, E. Lerut, A. Laenen +8 more
2014Journal of Cancer Research and Clinical Oncology35 citations Open access
Semantic Scholar
C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1
Chiranthani Sumanasekera, O. Kelemen, M. Beullens, Brandon E. Aubol +6 more
2011Nucleic Acids Research33 citations Open access
Semantic Scholar
Metals in the active site of native protein phosphatase-1.
Ewald Heroes, J. Rip, M. Beullens, L. van Meervelt +2 more
2015Journal of Inorganic Biochemistry30 citations
Semantic Scholar
A Role for PP1/NIPP1 in Steering Migration of Human Cancer Cells
Cristina Martín‐Granados, A. Prescott, Nele Van Dessel, A. Van Eynde +7 more
2012PLoS ONE30 citations Open access
Semantic Scholar
The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.
Mark A. Barber, A. Hendrickx, M. Beullens, H. Ceulemans +5 more
2012Biochemical Journal29 citations
Semantic Scholar
Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits
Toon Verheyen, Janina Görnemann, Iris Verbinnen, Shannah Boens +3 more
2015Nucleic Acids Research28 citations Open access
Semantic Scholar
Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.
Cenk Kığ, M. Beullens, Lijs Beke, A. Van Eynde +3 more
2013Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Synthesis and Characterization of Pseudocantharidins, Novel Phosphatase Modulators That Promote the Inclusion of Exon 7 into the SMN (Survival of Motoneuron) pre-mRNA*
Zhaiyi Zhang, O. Kelemen, Maria A. van Santen, Sharon M. Yelton +8 more
2011Journal of Biological Chemistry27 citations Open access
Semantic Scholar

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