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T. Taghian · SciRah

Researcher profile · Semantic Scholar

T. Taghian

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T. Taghian — researcher profile on SciRah

h-index: 11
Works: 38
Citations: 498

Most-cited papers

A Safe and Reliable Technique for CNS Delivery of AAV Vectors in the Cisterna Magna.
T. Taghian, M. Marosfoi, A. Puri, O. Cataltepe +19 more
2019Molecular Therapy99 citations Open access
Semantic Scholar
Modulation of cell function by electric field: a high-resolution analysis
T. Taghian, D. Narmoneva, A. Kogan
2015Journal of the Royal Society Interface99 citations Open access
Semantic Scholar
Regulation of endothelial MAPK/ERK signalling and capillary morphogenesis by low-amplitude electric field
Abdul Q. Sheikh, T. Taghian, B. Hemingway, Hongkwan Cho +2 more
2013Journal of the Royal Society Interface71 citations Open access
Semantic Scholar
Diabetes Alters Intracellular Calcium Transients in Cardiac Endothelial Cells
Abdul Q. Sheikh, Jennifer R. Hurley, Wei Huang, T. Taghian +4 more
2012PLoS ONE40 citations Open access
Semantic Scholar
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
Chantal M. Ferguson, B. Godinho, J. Alterman, Andrew H. Coles +14 more
2021JCI Insight32 citations Open access
Semantic Scholar
Pronounced Therapeutic Benefit of a Single Bidirectional AAV Vector Administered Systemically in Sandhoff Mice.
Hannah G Lahey, C. J. Webber, D. Golebiowski, C. Izzo +9 more
2020Molecular Therapy29 citations Open access
Semantic Scholar
Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases
Brett D. Story, M. Miller, Allison M. Bradbury, Emily D. Million +6 more
2020Frontiers in Veterinary Science23 citations Open access
Semantic Scholar
Real-time MR tracking of AAV gene therapy with βgal-responsive MR probe in a murine model of GM1-gangliosidosis
T. Taghian, A. Batista, Sarah G Kamper, Michael Caldwell +13 more
2021Molecular Therapy: Methods & Clinical Development15 citations Open access
Semantic Scholar
Angiogenic microenvironment augments impaired endothelial responses under diabetic conditions.
Abdul Q. Sheikh, Courtney Kuesel, T. Taghian, Jennifer R. Hurley +4 more
2014American Journal of Physiology - Cell Physiology14 citations Open access
Semantic Scholar
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease.
Jiaming Wang, Laura E Poskitt, Jillian Gallagher, E. Puffenberger +28 more
2025Science Translational Medicine12 citations
Semantic Scholar
Natural History of Tay-Sachs Disease in Sheep
Brett D. Story, T. Taghian, Jillian Gallagher, J. Koehler +17 more
2021Molecular Genetics and Metabolism11 citations Open access
Semantic Scholar
Brain Alterations in Aged OVT73 Sheep Model of Huntington’s Disease: An MRI Based Approach
T. Taghian, Jillian Gallagher, Erin Batcho, Caitlin Pullan +15 more
2022Journal of Huntington's Disease10 citations Open access
Semantic Scholar
Dual-vector rAAVrh8 gene therapy for GM2 gangliosidosis: a phase 1/2 trial
Florian Eichler, Oguz I. Cataltepe, R. Daci, Ajit S. Puri +32 more
2025Nature Medicine9 citations Open access
Semantic Scholar
Imaging NF-κB activity in a murine model of early stage diabetes
T. Taghian, Valeri Metelev, Su-Rong Zhang, A. Bogdanov
2019The FASEB Journal9 citations Open access
Semantic Scholar
A minimally invasive endovascular approach to the cerebellopontine angle cistern enables broad CNS biodistribution of scAAV9-CB-GFP
H. Benatti, Vania Anagnostakou, T. Taghian, Erin F. Hall +10 more
2024Molecular Therapy7 citations Open access
Semantic Scholar
Volume and Infusion Rate Dynamics of Intraparenchymal Central Nervous System Infusion in a Large Animal Model
T. Taghian, Erin Horn, M. Shazeeb, Lindsey Bierfeldt +11 more
2020Human Gene Therapy6 citations Open access
Semantic Scholar
Five-year analysis of efficacy and safety of a bidirectional AAV gene therapy in Tay-Sachs sheep
T. Taghian, Jillian Gallagher, Stephanie Bertrand, William C Baker +33 more
2025Journal of Clinical Investigation3 citations Open access
Semantic Scholar
Awake intracerebroventricular delivery and safety assessment of oligonucleotides in a large animal model
H. Benatti, Rachel Prestigiacomo, T. Taghian, Rachael Miller +14 more
2023Molecular Therapy: Methods & Clinical Development3 citations Open access
Semantic Scholar
Cerebrospinal Fluid Flow Enhancement (CFE) Increases the Spatial Distribution of Methotrexate after Intracerebroventricular Administration in a Sheep Model
H. Benatti, T. Taghian, Olivia Mihalek, Sarah Nath +11 more
2025Molecular Pharmaceutics2 citations
Semantic Scholar
BSLD-01 DYNAMIC CONTROL OF CSF FOR PERSONALIZED CNS DRUG DELIVERY FOR LEPTOMINGEAL DISEASE
P. Kumthekar, H. Benatti, T. Taghian, S. Nagpal +6 more
2023Neuro-Oncology Advances2 citations Open access
Semantic Scholar
INFORMATION DISTANCE AND ITS APPLICATION IN TIME SERIES
B. Mirza, T. Taghian, M. Sharifianpour
20082 citations
Semantic Scholar
Bioresponsive MR Imaging Probes for Noninvasive Monitoring of AAV Gene Therapy.
Jian-Hong Tang, T. Taghian, Srinivasan Jayakumar, Giacomo Parigi +4 more
2026Bioconjugate chemistry1 citations
Semantic Scholar
Levels of Synaptic Proteins in Brain and Neurofilament Light Chain in Cerebrospinal Fluid and Plasma of OVT73 Huntington’s Disease Sheep Support a Prodromal Disease State
E. Sapp, A. Boudi, S. Reid, Bianca A. Trombetta +7 more
2023Journal of Huntington's Disease1 citations Open access
Semantic Scholar
Cerebrospinal delivery of a bidirectional AAV9 vector improves optic nerve and retinal pathology in a sheep model of Tay-Sachs disease
Brett D Story, S. Thomasy, Sara A. Adelman, T. Taghian +18 more
2026Molecular Therapy0 citations Open access
Semantic Scholar
DDEL-01. ANIMAL STUDIES WITH A NEW CNS DRUG DELIVERY DEVICE TO EFFECTIVELY TREAT LEPTOMENINGEAL CARCINOMATOSIS PATIENTS
P. Kumthekar, H. Benatti, T. Taghian, W. Gormley +6 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
Near-infrared oligonucleotide duplex sensors for imaging rapidly activated transcription factors in vitro and in situ
A. Bogdanov, Valeri Metelev, T. Taghian, I. Solovyev +3 more
2019BiOS0 citations Open access
Semantic Scholar
Imaging Probes for Detecting Inflammation in the Mouse Model of Type 1 Diabetes
T. Taghian, Suresh Gupta, A. Dixon, Su-Rong Zhang +1 more
20170 citations
Semantic Scholar
Regulation of cellular function via electromagnetic field frequency and extracellular environment: A theoretical- experimental approach
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20150 citations
Semantic Scholar
Regulation of Cell Function via Extracellular Biophysical Environment: A Theoretical- Experimental Approach
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20150 citations Open access
Semantic Scholar
Interaction of an Electric Field with Vascular Cells
T. Taghian
20150 citations
Semantic Scholar
Co-regulation of cell behavior by electromagnetic stimulus and extracellular environment
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20140 citations
Semantic Scholar
The Role of Extracellular Environment in Regulation of Cellular Response to Electric Field
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20140 citations Open access
Semantic Scholar
Substrate Dependent Modulation of Cellular Response to External Electric Field
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20130 citations
Semantic Scholar
Frequency- dependent cell responses to an electromagnetic stimulus
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20130 citations
Semantic Scholar
Theoretical-Experimental Studies of Electric Field-Induced Cell Responses
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20130 citations Open access
Semantic Scholar
Frequency Dependent Regulation of Cell Behavior by Electrical Stimuli: a Theoretical-Experimental Approach
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20130 citations
Semantic Scholar
Interaction of Electric Fields with Vascular Cells
T. Taghian, Abdul Q. Sheikh, D. Narmoneva, A. Kogan
20120 citations
Semantic Scholar
Electric Field Stimulates Angiogenesis via Activation of MAPK/ERK Signaling in Microvascular Endothelial Cells
Abdul Q. Sheikh, T. Taghian, A. Kogan, D. Narmoneva
20120 citations
Semantic Scholar

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