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V. Lohmann · SciRah

Researcher profile · Semantic Scholar

V. Lohmann

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V. Lohmann — researcher profile on SciRah

h-index: 71
Works: 179
Citations: 20K

Most-cited papers

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
S. Reiss, Ilka Rebhan, P. Backes, I. Romero-Brey +20 more
2011Cell Host and Microbe527 citations Open access
Semantic Scholar
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
R. Bartenschlager, V. Lohmann, F. Penin
2013Nature Reviews Microbiology385 citations
Semantic Scholar
Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae
T. Postler, M. Beer, B. Blitvich, J. Bukh +11 more
2023Archives of Virology253 citations Open access
Semantic Scholar
Restoration of HCV-specific CD8+ T cell function by interferon-free therapy.
B. Martin, Nadine Hennecke, V. Lohmann, Antonin Kayser +4 more
2014Journal of Hepatology239 citations
Semantic Scholar
Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor.
S. Nkongolo, Y. Ni, F. Lempp, Christina Kaufman +6 more
2014Journal of Hepatology234 citations
Semantic Scholar
Dynamic Oscillation of Translation and Stress Granule Formation Mark the Cellular Response to Virus Infection
A. Ruggieri, E. Dazert, P. Metz, Sarah Hofmann +13 more
2012Cell Host and Microbe192 citations Open access
Semantic Scholar
Hepatitis C Virus RNA Replication
V. Lohmann
2013Current Topics in Microbiology and Immunology168 citations Open access
Semantic Scholar
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.
R. Bartenschlager, T. Baumert, J. Bukh, M. Houghton +8 more
2018Virus Research156 citations Open access
Semantic Scholar
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
C. Berger, I. Romero-Brey, Danijela Radujković, R. Terreux +8 more
2014Gastroenterology152 citations Open access
Semantic Scholar
Identification of type I and type II interferon‐induced effectors controlling hepatitis C virus replication
P. Metz, E. Dazert, A. Ruggieri, J. Mazur +9 more
2012Hepatology143 citations Open access
Semantic Scholar
Ultrastructure of the replication sites of positive-strand RNA viruses
C. Harak, V. Lohmann
2015Virology141 citations Open access
Semantic Scholar
The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A
S. Reiss, C. Harak, I. Romero-Brey, Danijela Radujković +5 more
2013PLoS Pathogens132 citations Open access
Semantic Scholar
Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
Hanna Roth, Vera Magg, Fabian Uch, P. Mutz +8 more
2017mBio131 citations Open access
Semantic Scholar
Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)*
M. Binder, Florian Eberle, Stefan Seitz, Norbert Mücke +6 more
2011Journal of Biological Chemistry129 citations Open access
Semantic Scholar
microRNA-122 amplifies hepatitis C virus translation by shaping the structure of the internal ribosomal entry site
P. Schult, Hanna Roth, R. L. Adams, C. Mas +5 more
2018Nature Communications110 citations Open access
Semantic Scholar
Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus
C. Dorobantu, L. Albulescu, C. Harak, Qian Feng +6 more
2015PLoS Pathogens109 citations Open access
Semantic Scholar
On the history of hepatitis C virus cell culture systems.
V. Lohmann, R. Bartenschlager
2014Journal of Medicinal Chemistry97 citations
Semantic Scholar
Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
Ina Karen Stoeck, Ji-Young Lee, K. Tabata, I. Romero-Brey +5 more
2017Journal of Virology87 citations Open access
Semantic Scholar
Monocytes Activate Natural Killer Cells via Inflammasome-induced Interleukin 18 in Response to Hepatitis C Virus Replication
E. Serti, Jens M. Werner, M. Chattergoon, A. Cox +2 more
2014Gastroenterology87 citations Open access
Semantic Scholar
Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle
M. Binder, Nurgazy Sulaimanov, Diana Clausznitzer, M. Schulze +7 more
2013PLoS Pathogens83 citations Open access
Semantic Scholar
Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation.
Vanesa Madan, David Paul, V. Lohmann, R. Bartenschlager
2014Gastroenterology82 citations
Semantic Scholar
Membrane alterations induced by nonstructural proteins of human norovirus
Sylvie Y. Doerflinger, M. Cortese, I. Romero-Brey, Zach Menne +7 more
2017PLoS Pathogens80 citations Open access
Semantic Scholar
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
K. Tabata, V. Prasad, David Paul, Ji-Young Lee +22 more
2021Nature Communications78 citations Open access
Semantic Scholar
NS5A Domain 1 and Polyprotein Cleavage Kinetics Are Critical for Induction of Double-Membrane Vesicles Associated with Hepatitis C Virus Replication
I. Romero-Brey, C. Berger, S. Kallis, Androniki Kolovou +3 more
2015mBio78 citations Open access
Semantic Scholar
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes.
Oliver Grünvogel, Ombretta Colasanti, Ji-Young Lee, Volker Klöss +18 more
2018Gastroenterology76 citations Open access
Semantic Scholar
A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes
M. Schmitt, N. Scrima, Danijela Radujković, C. Caillet-Saguy +7 more
2011Journal of Virology70 citations Open access
Semantic Scholar
Identification of HNRNPK as Regulator of Hepatitis C Virus Particle Production
Marion Poenisch, P. Metz, H. Blankenburg, A. Ruggieri +10 more
2015PLoS Pathogens62 citations Open access
Semantic Scholar
DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture
Oliver Grünvogel, K. Esser-Nobis, A. Reustle, P. Schult +10 more
2015Journal of Virology61 citations Open access
Semantic Scholar
Analysis of hepatitis C virus resistance to Silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B
K. Esser-Nobis, I. Romero-Brey, T. Ganten, J. Gouttenoire +12 more
2013Hepatology58 citations Open access
Semantic Scholar
Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A.
M. Hiet, Oliver Bauhofer, M. Zayas, Hanna Roth +10 more
2015Journal of Hepatology55 citations Open access
Semantic Scholar
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
C. Harak, M. Meyrath, I. Romero-Brey, C. Schenk +16 more
2016Nature Microbiology54 citations
Semantic Scholar
Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening.
J. Willemsen, O. Wicht, J. Wolanski, N. Baur +14 more
2017Molecules and Cells48 citations Open access
Semantic Scholar
Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein
C. Dorobantu, L. Albulescu, Heyrhyoung Lyoo, Mirjam Van Kampen +7 more
2016Msphere47 citations Open access
Semantic Scholar
Novel perspectives for hepatitis A virus therapy revealed by comparative analysis of hepatitis C virus and hepatitis A virus RNA replication
K. Esser-Nobis, C. Harak, P. Schult, Y. Kusov +1 more
2015Hepatology43 citations Open access
Semantic Scholar
Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo.
B. Seigel, B. Bengsch, V. Lohmann, R. Bartenschlager +2 more
2013Gastroenterology41 citations Open access
Semantic Scholar
Annexin A2 as a differential diagnostic marker of hepatocellular tumors.
T. Longerich, Maria Haller, Carolin Mogler, S. Aulmann +3 more
2011Pathology, Research and Practice37 citations
Semantic Scholar
Mapping of Functional Domains of the Lipid Kinase Phosphatidylinositol 4-Kinase Type III Alpha Involved in Enzymatic Activity and Hepatitis C Virus Replication
C. Harak, Danijela Radujković, Cyntia Taveneau, S. Reiss +3 more
2014Journal of Virology32 citations Open access
Semantic Scholar
Bile Acids Specifically Increase Hepatitis C Virus RNA-Replication
P. Chhatwal, D. Bankwitz, Juliane Gentzsch, A. Frentzen +3 more
2012PLoS ONE30 citations Open access
Semantic Scholar
Rapid Antigen Processing and Presentation of a Protective and Immunodominant HLA-B*27-restricted Hepatitis C Virus-specific CD8+ T-cell Epitope
J. Schmidt, A. Iversen, S. Tenzer, E. Gostick +9 more
2012PLoS Pathogens29 citations Open access
Semantic Scholar
Hepatitis C virus cell culture models: an encomium on basic research paving the road to therapy development
V. Lohmann
2018Medical Microbiology and Immmunology28 citations
Semantic Scholar
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
Aurélie Badillo, V. Receveur-Bréchot, S. Sarrazin, F. Cantrelle +11 more
2017Biochemistry27 citations Open access
Semantic Scholar
TCR-Redirected Human T Cells Inhibit Hepatitis C Virus Replication: Hepatotoxic Potential Is Linked to Antigen Specificity and Functional Avidity
A. Pasetto, L. Frelin, Soo Aleman, Fredrik Holmström +8 more
2012Journal of Immunology27 citations Open access
Semantic Scholar
Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation
Ombretta Colasanti, Rani Burm, Hao-En Huang, T. Riedl +18 more
2022bioRxiv21 citations Open access
Semantic Scholar
Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin
A. Wuestenberg, J. Kah, K. Singethan, H. Sirma +12 more
2014PLoS ONE21 citations Open access
Semantic Scholar
Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses
Qiang Chen, M. Coto-Llerena, A. Suslov, R. D. Teixeira +10 more
2021Nature Communications20 citations Open access
Semantic Scholar
Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis.
Julia Pollmann, Jana-Julia Götz, D. Rupp, Otto Strauss +10 more
2017Journal of Hepatology20 citations
Semantic Scholar
Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential.
Juandy Jo, B. Bengsch, B. Seigel, S. Rau +13 more
2012Journal of Hepatology20 citations
Semantic Scholar
Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties
Anangi Balasiddaiah, Haleh Davanian, Soo Aleman, A. Pasetto +6 more
2017Journal of Virology17 citations Open access
Semantic Scholar
Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα
C. Dorobantu, C. Harak, Rahel Klein, Lonneke van der Linden +4 more
2016Antimicrobial Agents and Chemotherapy17 citations Open access
Semantic Scholar
Biochemical and structural characterization of hepatitis A virus 2C reveals an unusual ribonuclease activity on single-stranded RNA
Pu Chen, J. Wojdyla, Ombretta Colasanti, Zhijian Li +4 more
2022Nucleic Acids Research16 citations Open access
Semantic Scholar

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