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Lvyi Chen · SciRah

Researcher profile · Semantic Scholar

Lvyi Chen

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Lvyi Chen — researcher profile on SciRah

h-index: 27
Works: 65
Citations: 2,208

Most-cited papers

Salidroside suppressing LPS‐induced myocardial injury by inhibiting ROS‐mediated PI3K/Akt/mTOR pathway in vitro and in vivo
Lvyi Chen, P. Liu, Xin Feng, Chun-Hua Ma
2017Journal of Cellular and Molecular Medicine242 citations Open access
Semantic Scholar
In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors.
Yong-Qiang Zhou, Wei-Ze Li, Lei Xu, Lvyi Chen
2011Environmental Toxicology and Pharmacology118 citations
Semantic Scholar
Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-κB/NLRP3 inflammasome activation via the AMPK/SIRT1 pathway.
Lvyi Chen, Z. Lan
2017Food & Function115 citations
Semantic Scholar
Anti-hyperuricemic and nephroprotective effects of Smilax china L.
Lvyi Chen, Huafeng Yin, Z. Lan, Shu-Wei Ma +4 more
2011Journal of Ethnopharmacology113 citations
Semantic Scholar
Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice.
Lvyi Chen, Z. Lan, Q. Lin, Xue Mi +5 more
2013Food and Chemical Toxicology110 citations
Semantic Scholar
Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in d-galactose-induced senescent mice.
Z. Lan, Ji-Ping Liu, Lvyi Chen, Qiang Fu +4 more
2012Journal of Ethnopharmacology95 citations
Semantic Scholar
Neuroprotective effect of ginkgolide K on glutamate-induced cytotoxicity in PC 12 cells via inhibition of ROS generation and Ca(2+) influx.
Shu-Wei Ma, Hong-Xia Liu, Haoyan Jiao, Li-Yan Wang +4 more
2012Neurotoxicology94 citations Open access
Semantic Scholar
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain
Xueming Hu, Lixia Du, Shenbin Liu, Z. Lan +14 more
2023Journal of Clinical Investigation84 citations Open access
Semantic Scholar
Piezo2 Channels Expressed by Colon-innervating TRPV1-lineage Neurons Mediate Visceral Mechanical Hypersensitivity
Zi-Li Xie, Jing Feng, T. Hibberd, B. Chen +8 more
2022Neuron76 citations Open access
Semantic Scholar
The mechanosensitive TRPV4 is required for crystal-induced inflammation ------ TRPV4 mediates crystal-induced inflammation
Z. Lan, Lvyi Chen, Jing Feng, Zi-Li Xie +16 more
2021Annals of the Rheumatic Diseases72 citations Open access
Semantic Scholar
Enhancement of intestinal absorption of akebia saponin D by borneol and probenecid in situ and in vitro.
Yong-Qiang Zhou, Wei-Ze Li, Lvyi Chen, Shu-Wei Ma +2 more
2010Environmental Toxicology and Pharmacology67 citations
Semantic Scholar
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Guang-Wen Shu, Xue Mi, Jian Cai, Xinlin Zhang +5 more
2013Toxicology Letters59 citations Open access
Semantic Scholar
Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis.
Zhi-guang Wen, Li Kang, Hudie Fu, Shengpeng Zhu +8 more
2023Carbohydrate Polymers57 citations
Semantic Scholar
Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF‐&kgr;B signaling pathway
Huafeng Yin, Li-Hao Huang, Ting Ouyang, Lvyi Chen
2018International Immunopharmacology54 citations
Semantic Scholar
Paeoniflorin attenuates amyloid-beta peptide-induced neurotoxicity by ameliorating oxidative stress and regulating the NGF-mediated signaling in rats.
Z. Lan, Lvyi Chen, Qiang Fu, Weiwei Ji +5 more
2013Brain Research51 citations
Semantic Scholar
Protective Effect of p-Cymene on Lipopolysaccharide-Induced Acute Lung Injury in Mice
Lvyi Chen, Lei Zhao, Chunfeng Zhang, Z. Lan
2014Inflammation49 citations
Semantic Scholar
Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats.
Lvyi Chen, Z. Lan, Yong-Qiang Zhou, Fei Li +4 more
2011Planta Medica44 citations
Semantic Scholar
Neuroprotective effect of ginkgolide K against acute ischemic stroke on middle cerebral ischemia occlusion in rats
Shu-Wei Ma, Huafeng Yin, Lvyi Chen, Hong-Xia Liu +2 more
2011Journal of Natural Medicines42 citations
Semantic Scholar
The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer’s disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome
Z. Lan, Guang-Jing Xie, Meng Wei, Ping Wang +1 more
2017OncoTarget37 citations Open access
Semantic Scholar
Doliroside A attenuates monosodium urate crystals-induced inflammation by targeting NLRP3 inflammasome.
Han-Song Wei, Chao Hu, Jin-Bo Xie, Chao Yang +5 more
2014European Journal of Pharmacology35 citations
Semantic Scholar
A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice.
Xian-Min Zhao, Guang-Wen Shu, Lvyi Chen, Xue Mi +2 more
2012Food and Chemical Toxicology35 citations
Semantic Scholar
Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway.
Hui Xiong, Shengnan Zhang, Zhongqiu Zhao, Ping Zhao +2 more
2018Journal of Ethnopharmacology34 citations Open access
Semantic Scholar
Methyl Gallate Improves Hyperuricemia Nephropathy Mice Through Inhibiting NLRP3 Pathway
Peng Liu, Wen Wang, Qiang Li, Xin Hu +6 more
2021Frontiers in Pharmacology33 citations Open access
Semantic Scholar
Hepatoprotection of Herpetospermum caudigerum Wall. against CCl4-induced liver fibrosis on rats.
Ming-Hui Li, Xin Feng, Da-Ji-Deng Ba, Cheng Chen +5 more
2019Journal of Ethnopharmacology29 citations
Semantic Scholar
Role of Sinomenine on Complete Freund's Adjuvant‐Induced Arthritis in Rats
Z. Lan, Meng Wei, Lvyi Chen, Guang-Jing Xie +2 more
2016IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology29 citations Open access
Semantic Scholar
Dolichos falcata Klein attenuated the inflammation induced by monosodium urate crystals in vivo and in vitro.
Lvyi Chen, M. Mola, Xu-Kun Deng, Zhi-Nan Mei +6 more
2013Journal of Ethnopharmacology29 citations
Semantic Scholar
Anti-Tumor Effects of Flavonoids from the Ethnic Medicine Docynia delavayi (Franch.) Schneid. and Its Possible Mechanism
Xu-Kun Deng, Xian-Min Zhao, Z. Lan, Jie Jiang +2 more
2014Journal of Medicinal Food27 citations
Semantic Scholar
Chrysanthemum morifolium attenuates metabolic and alcohol-associated liver disease via gut microbiota and PPARα/γ activation.
Dan Liu, Jianting Zhan, Shiqin Wang, Lvyi Chen +8 more
2024Phytomedicine26 citations
Semantic Scholar
Potential anti-gout properties of Wuwei Shexiang pills based on network pharmacology and pharmacological verification.
Li-Jie Bai, Chen-Hung Wu, Shuhui Lei, Min Zou +10 more
2023Journal of Ethnopharmacology26 citations
Semantic Scholar
Protective effect of luteolin on streptozotocin-induced diabetic renal damage in mice via the regulation of RIP140/NF-кB pathway and insulin signalling pathway
Lvyi Chen, Guowen Tian, Weidong Tang, Wei Luo +2 more
201626 citations Open access
Semantic Scholar
Integrating network pharmacology and pharmacological validation to explore the effect of Shi Wei Ru Xiang powder on suppressing hyperuricemia.
Qiang Li, P. Liu, Chen-Hung Wu, Li-Jie Bai +9 more
2022Journal of Ethnopharmacology22 citations Open access
Semantic Scholar
Combination of Polygoni Multiflori Radix Praeparata and Acori Tatarinowii Rhizoma Alleviates Learning and Memory Impairment in Scopolamine-Treated Mice by Regulating Synaptic-Related Proteins
Funan Ning, Lvyi Chen, Lin-Lin Chen, Xin Liu +7 more
2021Frontiers in Pharmacology21 citations Open access
Semantic Scholar
Piper longum L. ameliorates gout through the MAPK/PI3K-AKT pathway.
Chen-Hung Wu, Zhongyun Zhang, Li-Jie Bai, Shuhui Lei +7 more
2024Journal of Ethnopharmacology20 citations
Semantic Scholar
A Triterpenoid from Thalictrum fortunei Induces Apoptosis in BEL-7402 Cells Through the P53-Induced Apoptosis Pathway
Xian-Tao Zhang, Ming Zhao, Lvyi Chen, Haoyan Jiao +3 more
2011Molecules20 citations Open access
Semantic Scholar
Chemotherapy‐induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin
P. Liu, Li-Chun Ye, Yongshen Ren, Guo-Dun Zhao +13 more
2022British Journal of Pharmacology19 citations Open access
Semantic Scholar
Anti-inflammatory and anticancer activities of ethanol extract of pendulous monkshood root in vitro.
Xian-Ju Huang, W. Ren, Jun Li, Lvyi Chen +1 more
2013Asian Pacific Journal of Cancer Prevention19 citations Open access
Semantic Scholar
Gut Microbiota–Derived Tryptophan Indole Metabolites Ameliorate Collagen‐Induced Arthritis in Mice Via Aryl Hydrocarbon Receptor Activation
Liang Wu, Qiu-Ping Zhang, Zhi-Gang Tang, Yan-Hong Li +10 more
2025Arthritis & Rheumatology18 citations
Semantic Scholar
Comparison of the efficacy and safety of benzbromarone and febuxostat in gout and hyperuricemia: a systematic review and meta-analysis
Fan Wu, Lvyi Chen, Yimei Du
2024Clinical Rheumatology18 citations
Semantic Scholar
Epimedii Folium and Curculiginis Rhizoma ameliorate lipopolysaccharides-induced cognitive impairment by regulating the TREM2 signaling pathway.
K. Shi, Lvyi Chen, Lin-Lin Chen, Ai-Hua Tan +5 more
2021Journal of Ethnopharmacology17 citations
Semantic Scholar
Cis-resveratrol blocks crystal-induced NLRP3 inflammasome activation via the TRPV4-Ca²⁺-phagocytosis-ROS axis.
Shuhui Lei, Kaiqun Liu, Cong Liu, Ran An +8 more
2025Phytomedicine16 citations
Semantic Scholar
Hepatoprotective effect of Herpetospermum caudigerum Wall. on carbon tetrachloride‐induced hepatic fibrosis in rats
Xin Feng, Ge-Jia Zhong, Da-Ji-Deng Ba, Bin Yang +2 more
2018Journal of Cellular and Molecular Medicine16 citations Open access
Semantic Scholar
Safety assessment of saponins extract in Dolichos falcatus Klein: Subchronic study in Sprague-Dawley rats.
Z. Lan, Chao Hu, Ya-Min Huang, Lvyi Chen +5 more
2015Journal of Ethnopharmacology12 citations
Semantic Scholar
Attenuation of Gouty Arthritis by Emodinol in Monosodium Urate Crystal-Treated Mice
Lvyi Chen, Z. Lan, Shu-Wei Ma, Ling Zhao +1 more
2013Planta Medica12 citations
Semantic Scholar
Benzoylmesaconine mitigates NLRP3 inflammasome-related diseases by reducing intracellular K+ efflux and disrupting NLRP3 inflammasome assembly.
Zhongyun Zhang, Chen-Hung Wu, Zilu Bao, Zhaoxiang Ren +9 more
2024Phytomedicine11 citations
Semantic Scholar
Polygoni Multiflori Radix Praeparata and Acori Tatarinowii Rhizoma ameliorate scopolamine-induced cognitive impairment by regulating the cholinergic and synaptic associated proteins.
Yuman Xie, Li Liu, Junzuo Zheng, K. Shi +5 more
2023Journal of Ethnopharmacology11 citations
Semantic Scholar
The immunosuppressive effects and mechanisms of loureirin B on collagen-induced arthritis in rats
Yan Zou, Qianru Zhao, Xu Zhang, Hui Yu +10 more
2023Frontiers in Immunology11 citations Open access
Semantic Scholar
The mechanosensitive TRPV4 is required for crystal-induced inflammation
Lvyi Chen
202111 citations
Semantic Scholar
Two new phenylpropanoids isolated from the rhizomes of Alpinia galanga
Ling Zhao, Lvyi Chen, Jing-Yu Liang
201210 citations
Semantic Scholar
Effects of Kv1.3 knockout on pyramidal neuron excitability and synaptic plasticity in piriform cortex of mice
Yong-Xin Zhou, Haobo Tao, Si-si Lv, Ke-Qin Liang +7 more
2024Acta Pharmacologica Sinica6 citations Open access
Semantic Scholar
Ergothioneine Attenuates CCl4‐Induced Acute Liver Injury by Inhibiting Oxidative Stress and Apoptosis via Regulating LKB1/Nrf2 Pathway
Tiantian Zhang, Xiao Lei, Guangqiong Li, Zhiyong Zheng +5 more
2025The FASEB Journal5 citations
Semantic Scholar

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