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Takafumi Senokuchi · SciRah

Researcher profile · Semantic Scholar

Takafumi Senokuchi

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Takafumi Senokuchi — researcher profile on SciRah

h-index: 26
Works: 71
Citations: 2,329

Most-cited papers

SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.
T. Yoshizawa, M. Karim, Yoshifumi Sato, Takafumi Senokuchi +18 more
2014Cell Metabolism204 citations Open access
Semantic Scholar
Statins Activate Peroxisome Proliferator-Activated Receptor γ Through Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase–Dependent Cyclooxygenase-2 Expression in Macrophages
M. Yano, T. Matsumura, Takafumi Senokuchi, Norio Ishii +11 more
2007Circulation Research195 citations Open access
Semantic Scholar
Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice.
T. Seimon, Yi-Bin Wang, Seongah Han, Takafumi Senokuchi +4 more
2009Journal of Clinical Investigation188 citations Open access
Semantic Scholar
The Macrophage at the Crossroads of Insulin Resistance and Atherosclerosis
Chien-ping Liang, Seongah Han, Takafumi Senokuchi, A. Tall
2007Circulation Research146 citations Open access
Semantic Scholar
Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice*
M. Yano, Ken Watanabe, Tadashi Yamamoto, K. Ikeda +15 more
2010Journal of Biological Chemistry144 citations Open access
Semantic Scholar
Sirt7 Contributes to Myocardial Tissue Repair by Maintaining Transforming Growth Factor-&bgr; Signaling Pathway
S. Araki, Y. Izumiya, T. Rokutanda, Alessandro Ianni +12 more
2015Circulation106 citations
Semantic Scholar
Hyperglycemia Induces Cellular Hypoxia through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1
Kiminori Sada, T. Nishikawa, Daisuke Kukidome, T. Yoshinaga +6 more
2016PLoS ONE100 citations Open access
Semantic Scholar
Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.
Seongah Han, Chien-ping Liang, M. Westerterp, Takafumi Senokuchi +5 more
2009Journal of Clinical Investigation98 citations Open access
Semantic Scholar
Statins Suppress Oxidized Low Density Lipoprotein-induced Macrophage Proliferation by Inactivation of the Small G Protein-p38 MAPK Pathway*
Takafumi Senokuchi, T. Matsumura, M. Sakai, M. Yano +9 more
2005Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress
Takafumi Senokuchi, Chien-ping Liang, T. Seimon, Seongah Han +7 more
2008Diabetes88 citations Open access
Semantic Scholar
Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line.
K. Yamagata, Takafumi Senokuchi, Meihong Lu, M. Takemoto +8 more
2011Biochemical and Biophysical Research Communications - BBRC83 citations
Semantic Scholar
Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein.
Takafumi Senokuchi, T. Matsumura, M. Sakai, T. Matsuo +6 more
2004Atherosclerosis73 citations
Semantic Scholar
Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages
Y. Higuchi, Nobuaki Shiraki, Keitaro Yamane, Zeng Qin +7 more
2010Journal of Cell Science70 citations Open access
Semantic Scholar
Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice
Satoko Hanatani, H. Motoshima, Yuki Takaki, Shuji Kawasaki +10 more
2016Journal of clinical biochemistry and nutrition60 citations Open access
Semantic Scholar
Oxidized Low Density Lipoprotein Activates Peroxisome Proliferator-activated Receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 Expression in Macrophages*
Kayo Taketa, T. Matsumura, M. Yano, Norio Ishii +10 more
2008Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Telmisartan Exerts Antiatherosclerotic Effects by Activating Peroxisome Proliferator-Activated Receptor-&ggr; in Macrophages
T. Matsumura, H. Kinoshita, Norio Ishii, K. Fukuda +8 more
2011Arteriosclerosis, Thrombosis and Vascular Biology53 citations
Semantic Scholar
SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL Published, JLR Papers in Press, October 24, 2007.
L. Yvan-Charvet, T. Pagler, Nan Wang, Takafumi Senokuchi +4 more
2008Journal of Lipid Research51 citations Open access
Semantic Scholar
Activation of AMP-activated Protein Kinase Suppresses Oxidized Low-density Lipoprotein-induced Macrophage Proliferation*
Norio Ishii, T. Matsumura, H. Kinoshita, H. Motoshima +8 more
2009Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Novel function of transthyretin in pancreatic alpha cells
Yu Su, H. Jono, Y. Misumi, Takafumi Senokuchi +9 more
2012FEBS Letters46 citations Open access
Semantic Scholar
Identification of microRNA that represses IRS-1 expression in liver
Kaoru Ono, M. Igata, Tatsuya Kondo, Sayaka Kitano +9 more
2018PLoS ONE42 citations Open access
Semantic Scholar
Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan
R. Tateishi, Takeshi Matsumura, T. Okanoue, T. Shima +22 more
2021Journal of gastroenterology40 citations Open access
Semantic Scholar
Nifedipine Induces Peroxisome Proliferator-Activated Receptor-&ggr; Activation in Macrophages and Suppresses the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice
Norio Ishii, T. Matsumura, H. Kinoshita, K. Fukuda +10 more
2010Arteriosclerosis, Thrombosis and Vascular Biology39 citations Open access
Semantic Scholar
Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes
T. Matsumura, Kayo Taketa, H. Motoshima, Takafumi Senokuchi +11 more
2013Cardiovascular Diabetology37 citations Open access
Semantic Scholar
Inhibition of Local Macrophage Growth Ameliorates Focal Inflammation and Suppresses Atherosclerosis
Sarie Yamada, Takafumi Senokuchi, T. Matsumura, Yutaro Morita +13 more
2018Arteriosclerosis, Thrombosis and Vascular Biology36 citations Open access
Semantic Scholar
Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages.
H. Kinoshita, T. Matsumura, Norio Ishii, K. Fukuda +9 more
2013Biochemical and Biophysical Research Communications - BBRC31 citations
Semantic Scholar
Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation.
K. Fukuda, T. Matsumura, Takafumi Senokuchi, Norio Ishii +11 more
2015Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
A 1‐year, prospective, observational study of Japanese outpatients with type 1 and type 2 diabetes switching from insulin glargine or detemir to insulin degludec in basal–bolus insulin therapy (Kumamoto Insulin Degludec Observational study)
S. Shimoda, Miki Sato, T. Sekigami, H. Motoshima +43 more
2016Journal of Diabetes Investigation24 citations Open access
Semantic Scholar
Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes
Tatsuya Kondo, Nobukazu Miyakawa, H. Motoshima, Satoko Hanatani +9 more
2018Journal of Diabetes Investigation20 citations Open access
Semantic Scholar
Orally administrated acetate inhibits atherosclerosis progression through AMPK activation via GPR43 in plaque macrophages.
Toshiaki Wada, Takafumi Senokuchi, Yu-Dan Shi, Tatsuya Furusho +10 more
2024Atherosclerosis18 citations Open access
Semantic Scholar
15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB.
T. Matsuo, T. Matsumura, M. Sakai, Takafumi Senokuchi +8 more
2004Biochemical and Biophysical Research Communications - BBRC16 citations
Semantic Scholar
Inhibition of inflammation-mediated DPP-4 expression by linagliptin increases M2 macrophages in atherosclerotic lesions.
S. Nishida, T. Matsumura, Takafumi Senokuchi, Saiko Murakami-Nishida +6 more
2020Biochemical and Biophysical Research Communications - BBRC15 citations
Semantic Scholar
Impact of tissue macrophage proliferation on peripheral and systemic insulin resistance in obese mice with diabetes
Yutaro Morita, Takafumi Senokuchi, Sarie Yamada, Toshiaki Wada +9 more
2020BMJ Open Diabetes Research & Care12 citations Open access
Semantic Scholar
Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ.
Saiko Murakami-Nishida, T. Matsumura, Takafumi Senokuchi, Norio Ishii +8 more
2019Atherosclerosis12 citations
Semantic Scholar
Troglitazone inhibits oxidized low-density lipoprotein-induced macrophage proliferation: impact of the suppression of nuclear translocation of ERK1/2.
M. Yano, T. Matsumura, Takafumi Senokuchi, Norio Ishii +9 more
2007Atherosclerosis11 citations
Semantic Scholar
Factors Affecting Human Damage in Heavy Rains and Typhoon Disasters.
H. Naito, D. Sueta, Satoko Hanatani, H. Ikeda +6 more
2022Tohoku journal of experimental medicine9 citations Open access
Semantic Scholar
Sirt7 Deficiency Attenuates Neointimal Formation Following Vascular Injury by Modulating Vascular Smooth Muscle Cell Proliferation.
Yuichi Kimura, Y. Izumiya, S. Araki, S. Yamamura +16 more
2021Circulation Journal9 citations Open access
Semantic Scholar
The Occurrence of Islet Amyloid Polypeptide Amyloidosis in Japanese Subjects
Yu Su, Y. Misumi, M. Ueda, Makoto Shono +7 more
2012Pancreas9 citations
Semantic Scholar
The benefits and accuracy of real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes attending a summer camp
Tatsuya Kondo, Takafumi Senokuchi, J. Morinaga, A. Miyashita +4 more
2024Journal of Diabetes Investigation4 citations
Semantic Scholar
Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice.
Shuji Kawasaki, H. Motoshima, Satoko Hanatani, Yuki Takaki +12 more
2013Biochemical and Biophysical Research Communications - BBRC4 citations
Semantic Scholar
Sirt 7 Contributes to Myocardial Tissue Repair by Maintaining TGF-Signaling Pathway
S. Araki, Y. Izumiya, T. Rokutanda, Alessandro Ianni +12 more
20153 citations
Semantic Scholar
Hematopoietic dipeptidyl peptidase-4 deficiency promotes M2 macrophage polarization and attenuates atherosclerosis.
Yu-Qi Zhou, T. Matsumura, S. Saito, Yoshitaka Yagi +11 more
2025Biochemical and Biophysical Research Communications - BBRC2 citations Open access
Semantic Scholar
Potent anti-obesity effect of acetate; acetate may alter the expression of genes involved in beige adipogenesis in obese KK-Ay mice
H. Motoshima, Satoko Hanatani, Yuki Takaki, Shuji Kawasaki +8 more
20162 citations
Semantic Scholar
Evaluation of a new device for measurement of hemoglobin A1c for Japanese subjects
S. Shimoda, Takako Maeda, N. Furukawa, K. Ichinose +5 more
2013Diabetology International2 citations
Semantic Scholar
Corrigendum to “Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein”[Atherosclerosis, 2004, 176 (2): 233–245]
Takafumi Senokuchi, T. Matsumura, M. Sakai, T. Matsuo +6 more
20042 citations
Semantic Scholar
Impact of Endothelium-Derived Mitochondrial Reactive Oxygen Species on Obesity-Associated Atherosclerosis
T. Yoshinaga, T. Matsumura, Nobuhiro Kajihara, Yoshitaka Yagi +11 more
2026Antioxidants and Redox Signaling1 citations
Semantic Scholar
Benefits and Accuracy of Real-Time CGM in Children and Adolescents with Type 1 Diabetes Attending Summer Camp: 2nd year.
Tatsuya Kondo, Takafumi Senokuchi, Mayumi Yano, Haruo Takeda +3 more
2025Journal of Clinical Endocrinology and Metabolism1 citations
Semantic Scholar
New perspectives on insulin therapy
E. Araki, Hirotaka Araki, Takafumi Senokuchi, H. Motoshima
2020Journal of Diabetes Investigation1 citations Open access
Semantic Scholar
Title Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancrea
Y. Higuchi, Nobuaki Shiraki, Keitaro Yamane, Zeng Qin +9 more
20181 citations
Semantic Scholar
Impacts of tight multifactorial intervention in patients with type 2 diabetes: Implications from the Japan Diabetes Outcome Intervention Trial 3
E. Araki, Takafumi Senokuchi, N. Furukawa
2018Journal of Diabetes Investigation1 citations Open access
Semantic Scholar
Abstract 9663: Sirt7 Contributes to Proper Wound Healing After Murine Model of Myocardial Infarction by Modulating the Fibroblast Differentiation
S. Araki, Y. Izumiya, Takafumi Senokuchi, T. Rokutanda +5 more
2011Circulation1 citations
Semantic Scholar

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E. Araki×31
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E. Araki — researcher profile on SciRah
T. Matsumura×27
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T. Matsumura — researcher profile on SciRah
H. Motoshima×23
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H. Motoshima — researcher profile on SciRah
Norio Ishii×19
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Daisuke Kukidome×13

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K. Yamagata×12

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K. Yamagata — researcher profile on SciRah

Tatsuya Kondo×11

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M. Yano — researcher profile on SciRah

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Shuji Kawasaki — researcher profile on SciRah