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J. Crabtree · SciRah

Researcher profile · Semantic Scholar

J. Crabtree

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J. Crabtree — researcher profile on SciRah

h-index: 32
Works: 67
Citations: 5,936

Most-cited papers

Positional cloning of the gene for multiple endocrine neoplasia-type 1.
S. Chandrasekharappa, S. Guru, P. Manickam, S. Olufemi +19 more
1997Science2,009 citations
Semantic Scholar
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors.
J. Crabtree, P. Scacheri, Jerrold M. Ward, L. Garrett-Beal +8 more
2001Proceedings of the National Academy of Sciences of the United States of America447 citations Open access
Semantic Scholar
Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas.
Z. Zhuang, A. Vortmeyer, S. Pack, Steve C. Huang +23 more
1997Cancer Research308 citations
Semantic Scholar
Targeting Notch in oncology: the path forward
Samarpan Majumder, J. Crabtree, T. Golde, L. Minter +2 more
2020Nature reviews. Drug discovery249 citations
Semantic Scholar
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung.
L. Debelenko, E. Brambilla, S. Agarwal, J. I. Swalwell +17 more
1997Human Molecular Genetics241 citations
Semantic Scholar
Mutations of the MEN1 tumor suppressor gene in pituitary tumors.
Z. Zhuang, S. Ezzat, A. Vortmeyer, R. Weil +21 more
1997Cancer Research240 citations
Semantic Scholar
Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout
J. Crabtree, P. Scacheri, Jerrold M. Ward, Sara R. McNally +13 more
2003Molecular and Cellular Biology239 citations Open access
Semantic Scholar
Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias.
S. Marx, S. Agarwal, M. Kester, C. Heppner +19 more
1999Recent Progress in Hormone Research177 citations
Semantic Scholar
Molecular Pathology of the MEN1 Gene
S. Agarwal, A. Burns, Karen E. Sukhodolets, P. Kennedy +23 more
2004Annals of the New York Academy of Sciences154 citations Open access
Semantic Scholar
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter
S. Agarwal, E. Novotny, J. Crabtree, J. Weitzman +6 more
2003Proceedings of the National Academy of Sciences of the United States of America141 citations Open access
Semantic Scholar
The 32-Kilodalton Subunit of Replication Protein A Interacts with Menin, the Product of the MEN1 Tumor Suppressor Gene
Karen E. Sukhodolets, A. Hickman, S. Agarwal, Maxim V. Sukhodolets +8 more
2003Molecular and Cellular Biology134 citations Open access
Semantic Scholar
A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus.
S. Guru, S. Agarwal, P. Manickam, S. Olufemi +14 more
1997Genome Research126 citations Open access
Semantic Scholar
Bidirectional transcriptional activity of PGK‐neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice
P. Scacheri, J. Crabtree, E. Novotny, L. Garrett-Beal +6 more
2001Genesis116 citations
Semantic Scholar
Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism.
S. Libutti, J. Crabtree, D. Lorang, A. Burns +13 more
2003Cancer Research104 citations
Semantic Scholar
Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway.
J. Crabtree, S. Jelinsky, H. Harris, Sung E. Choe +14 more
2009Cancer Research102 citations Open access
Semantic Scholar
Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways
Fokhrul M. Hossain, C. Sorrentino, Deniz A. Ucar, Yin Peng +13 more
2018Frontiers in Oncology94 citations Open access
Semantic Scholar
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms
James C. Yao, E. Bergsland, R. Aggarwal, A. Aparicio +8 more
2022The Oncologist92 citations Open access
Semantic Scholar
Effects of various selective estrogen receptor modulators with or without conjugated estrogens on mouse mammary gland.
B. Peano, J. Crabtree, B. Komm, R. Winneker +1 more
2009Endocrinology92 citations
Semantic Scholar
Notch Signaling in Neuroendocrine Tumors
J. Crabtree, Ciera S. Singleton, L. Miele
2016Frontiers in Oncology84 citations Open access
Semantic Scholar
DNA Isolation and Sequencing
B. Roe, J. Crabtree, Akbar S. Khan
199664 citations
Semantic Scholar
A mouse model of androgenetic alopecia.
J. Crabtree, E. Kilbourne, B. Peano, S. Chippari +7 more
2010Endocrinology63 citations
Semantic Scholar
Breast Cancer Stem Cells
J. Crabtree, L. Miele
2018Biomedicines62 citations Open access
Semantic Scholar
Activity of three selective estrogen receptor modulators on hormone-dependent responses in the mouse uterus and mammary gland.
J. Crabtree, B. Peano, Xiaochun Zhang, B. Komm +2 more
2008Molecular and Cellular Endocrinology62 citations
Semantic Scholar
Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1
P. Scacheri, J. Crabtree, A. Kennedy, Gary P. Swain +4 more
2004Mammalian Genome58 citations
Semantic Scholar
Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region
P. Manickam, S. Guru, L. Debelenko, S. Agarwal +16 more
1997Human Genetics57 citations
Semantic Scholar
miR-24 regulates menin in the endocrine pancreas.
J. Vijayaraghavan, Elaine C. Maggi, J. Crabtree
2014American Journal of Physiology. Endocrinology and Metabolism51 citations
Semantic Scholar
A study of 17beta-estradiol-regulated genes in the vagina of postmenopausal women with vaginal atrophy.
M. Cotreau, Vargheese M. Chennathukuzhi, H. Harris, Lixin Han +9 more
2007Maturitas44 citations
Semantic Scholar
A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13.
S. Guru, S. Olufemi, P. Manickam, Christiano Cummings +20 more
1997Genomics40 citations
Semantic Scholar
Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families
S. Agarwal, L. Debelenko, M. Kester, S. Guru +15 more
1998Human Mutation39 citations Open access
Semantic Scholar
The gene for multiple endocrine neoplasia type 1: recent findings.
S. Marx, S. Agarwal, C. Heppner, Young-Min Kim +15 more
1999Bone36 citations
Semantic Scholar
The complete nucleotide sequences of the SacBII Kan domain of the P1 pAD10-SacBII cloning vector and three cosmid cloning vectors: pTCF, svPHEP, and LAWRIST16.
H. Pan, Ying-Ping Wang, S. Chissoe, A. Bodenteich +5 more
1994Genetic analysis, techniques and applications34 citations
Semantic Scholar
Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene
S. Guru, J. Crabtree, K. Brown, K. Dunn +9 more
1999Mammalian Genome33 citations
Semantic Scholar
Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone-regulated gene markers.
J. Crabtree, Xiaochun Zhang, B. Peano, Zhi-Ming Zhang +2 more
2006Journal of Steroid Biochemistry and Molecular Biology29 citations
Semantic Scholar
Loss of Inhibitory IRS-1 Phosphorylation is an Early Event in mTOR-Dependent Endometrial Hyperplasia and Carcinoma
A. Mccampbell, H. Harris, J. Crabtree, R. Winneker +2 more
2010Cancer Prevention Research22 citations Open access
Semantic Scholar
Molecular analysis of the vaginal response to estrogens in the ovariectomized rat and postmenopausal woman
S. Jelinsky, Sung E. Choe, J. Crabtree, M. Cotreau +8 more
2008BMC Medical Genomics18 citations Open access
Semantic Scholar
Epigenetic Regulation in Gastroenteropancreatic Neuroendocrine Tumors
J. Crabtree
2022Frontiers in Oncology15 citations Open access
Semantic Scholar
Clinical and Preclinical Advances in Gastroenteropancreatic Neuroendocrine Tumor Therapy
J. Crabtree
2017Frontiers in Endocrinology14 citations Open access
Semantic Scholar
ISGylation is increased in the peripheral blood mononuclear cells derived from symptomatic COVID-19 patients
Joshua Schwartzenburg, Ryan E. Reed, H. Koul, A. Zea +4 more
2022Experimental biology and medicine10 citations Open access
Semantic Scholar
The Complete Nucleotide Sequences of the pSacBII P1 Cloning Vector and Three Cosmid Cloning Vectors: pTCF, svPHEP, and LAWRIST16
B. Roe, J. Crabtree, S. Clifton, K. Iyer +4 more
19947 citations
Semantic Scholar
Neuroendocrine tumors: current therapies, notch signaling, and cancer stem cells
J. Crabtree, L. Miele
20166 citations Open access
Semantic Scholar
Acquisition of an oncogenic fusion protein is sufficient to globally alter the landscape of miRNA expression to inhibit myogenic differentiation
Jacob M. Loupe, P. Miller, J. Crabtree, J. Zabaleta +1 more
2017OncoTarget5 citations Open access
Semantic Scholar
Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects
Jacob M. Loupe, P. Miller, B. P. Bonner, Elaine C. Maggi +6 more
2016OncoTarget4 citations Open access
Semantic Scholar
The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
Wendy M. McKimpson, Zi-Qiang Yuan, Min Zheng, J. Crabtree +2 more
2015PLoS ONE4 citations Open access
Semantic Scholar
Precision diagnostics in cancer: Predict, prevent, and personalize.
J. Crabtree, Lucio Miele
2022Progress in Molecular Biology and Translational Science3 citations
Semantic Scholar
Effects of Various SERMs with or without Conjugated Estrogens on Mouse Mammary Gland
B. Peano, J. Crabtree, B. Komm, R. Winneker +1 more
20093 citations Open access
Semantic Scholar
ER+ Breast Cancer Mammosphere Formation and Analysis.
Ciera S. Singleton, L. Chan, K. McCulley, S. Kessel +2 more
2021Methods in molecular biology2 citations
Semantic Scholar
Fundamentals of epigenetics
J. Crabtree
20202 citations
Semantic Scholar
Non‐cannonical notch signaling pathways regulate breast cancer stem‐like cells function in triple negative breast cancer
Fokhrul M. Hossain, C. Sorrentino, A. Bilyeu, J. Crabtree +4 more
2017The FASEB Journal2 citations Open access
Semantic Scholar
Fundamentals of heredity
J. Crabtree
20201 citations
Semantic Scholar
Novel targets in the treatment of neuroendocrine tumors: RBP2
Elaine C. Maggi, J. Crabtree
20171 citations
Semantic Scholar

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S. Chandrasekharappa×17
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S. Chandrasekharappa — researcher profile on SciRah
S. Marx×14
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A. Burns×13
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S. Guru×11
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P. Manickam — researcher profile on SciRah

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