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A. Takashima · SciRah

Researcher profile · Semantic Scholar

A. Takashima

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A. Takashima — researcher profile on SciRah

h-index: 37
Works: 368
Citations: 4,805

Most-cited papers

Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer
K. Shitara, K. Muro, J. Watanabe, K. Yamazaki +27 more
2024Nature Medicine118 citations Open access
Semantic Scholar
Trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-overexpressing/amplified (HER2+) metastatic colorectal cancer (mCRC): Primary results from the multicenter, randomized, phase 2 DESTINY-CRC02 study.
K. Raghav, S. Siena, A. Takashima, T. Kato +16 more
2023Journal of Clinical Oncology55 citations Open access
Semantic Scholar
Olaparib with or without bevacizumab versus bevacizumab plus a fluoropyrimidine as maintenance therapy in advanced colorectal cancer: The randomized phase 3 LYNK-003 study.
A. Takashima, P. García-Alfonso, Raimundo Manneh, A. A. Besen +11 more
2024European Journal of Cancer20 citations Open access
Semantic Scholar
A multi-institutional observational study evaluating the incidence and the clinicopathological characteristics of NeoRAS wild-type metastatic colorectal cancer
H. Osumi, A. Takashima, A. Ooki, Yuri Yoshinari +17 more
2023Translational Oncology19 citations Open access
Semantic Scholar
Rivoceranib, a VEGFR-2 inhibitor, monotherapy in previously treated patients with advanced or metastatic gastric or gastroesophageal junction cancer (ANGEL study): an international, randomized, placebo-controlled, phase 3 trial
Yoon-Koo Kang, M. Ryu, M. Di Bartolomeo, I. Chau +14 more
2024Gastric Cancer18 citations Open access
Semantic Scholar
A Learning Program for Treatment Recommendations by Molecular Tumor Boards and Artificial Intelligence
K. Sunami, Yoichi Naito, Y. Saigusa, T. Amano +31 more
2023JAMA Oncology16 citations Open access
Semantic Scholar
Trifluridine/tipiracil+bevacizumab (BEV) vs. fluoropyrimidine-irinotecan+BEV as second-line therapy for metastatic colorectal cancer: a randomised noninferiority trial
Y. Kuboki, T. Terazawa, T. Masuishi, Masato Nakamura +20 more
2023British Journal of Cancer14 citations Open access
Semantic Scholar
Oxaliplatin Added to Fluoropyrimidine/Bevacizumab as Initial Therapy for Unresectable Metastatic Colorectal Cancer in Older Patients: A Multicenter, Randomized, Open-Label Phase III Trial (JCOG1018)
A. Takashima, T. Hamaguchi, J. Mizusawa, Fumio Nagashima +16 more
2024Journal of Clinical Oncology13 citations
Semantic Scholar
A comprehensive appraisal of HER2 heterogeneity in HER2-amplified and HER2-low colorectal cancer
T. Hashimoto, D. Takayanagi, Junpei Yonemaru, Tomoaki Naka +9 more
2023British Journal of Cancer12 citations Open access
Semantic Scholar
Characteristics of anal canal squamous cell carcinoma as an HPV-associated cancer in Japan
Kazutaka Yamada, K. Shiraishi, A. Takashima, D. Takayanagi +12 more
2023International Journal of Clinical Oncology12 citations
Semantic Scholar
Comparison of clinicopathological and genomic profiles in anal squamous cell carcinoma between Japanese and Caucasian cohorts
Takahiko Ito, D. Takayanagi, S. Sekine, T. Hashimoto +11 more
2023Scientific Reports10 citations Open access
Semantic Scholar
Randomized Phase II/III Trial Comparing Hepatectomy, Followed by mFOLFOX6 With Hepatectomy Alone for Liver Metastasis From Colorectal Cancer: Long-Term Results of JCOG0603
Y. Kanemitsu, Yasuhiro Shimizu, J. Mizusawa, Yoshitaka Inaba +16 more
2026Journal of Clinical Oncology9 citations Open access
Semantic Scholar
Implementing generative artificial intelligence in precision oncology: safety, governance, and significance
R. Hamamoto, T. Koyama, Satoshi Takahashi, T. Yasuda +23 more
2026Journal of Hematology & Oncology8 citations Open access
Semantic Scholar
Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database
H. Fujii, H. Hirano, K. Shiraishi, H. Shoji +5 more
2024JCO Precision Oncology8 citations
Semantic Scholar
Efficacy of anti-epidermal growth factor antibody rechallenge in RAS/BRAF wild-type metastatic colorectal cancer: a multi-institutional observational study
K. Fukuda, H. Osumi, Y. Yoshinami, A. Ooki +17 more
2024Journal of Cancer Research and Clinical Oncology7 citations Open access
Semantic Scholar
Safety and Efficacy of Encorafenib, Binimetinib, and Cetuximab for BRAFV600E-Mutant Metastatic Colorectal Cancer: Results of the Japanese Expanded Access Program.
D. Kotani, A. Takashima, T. Kato, T. Satoh +15 more
2024Clinical colorectal cancer7 citations Open access
Semantic Scholar
Phase 1 trial of the anti-LAG3 antibody favezelimab plus pembrolizumab in advanced gastric cancer.
S. Rha, W. Miller, M. D. de Miguel, S. Im +9 more
2023Journal of Clinical Oncology7 citations
Semantic Scholar
Longitudinal ctDNA monitoring and prediction of anti-EGFR rechallenge outcomes in RAS/BRAF wild-type metastatic colorectal cancer (mCRC): The REMARRY & PURSUIT trials.
Y. Kagawa, H. Taniguchi, D. Kotani, T. Hashimoto +16 more
2025Journal of Clinical Oncology6 citations
Semantic Scholar
Retrospective Analysis of Definitive Chemoradiotherapy With FOLFOX in Patients With Esophageal Cancer Intolerant to Cisplatin
Mayu Yada, S. Yamamoto, Y. Honma, H. Hirano +6 more
2024In Vivo6 citations Open access
Semantic Scholar
First report of the randomized phase III study of bi-weekly trifluridine/tipiracil (FTD/TPI) plus bevacizumab (BEV) vs. FTD/TPI monotherapy for chemorefractory metastatic colorectal cancer (mCRC): JCOG2014 (ROBiTS).
Hironaga Satake, K. Yamazaki, Y. Suwa, T. Tsushima +16 more
2024Journal of Clinical Oncology6 citations Open access
Semantic Scholar
Feasibility of antibiotic-assisted fecal microbiota transplantation with immunotherapy for esophageal and gastric cancer
Y. Yoshinami, S. Yamaguchi, H. Shoji, N. Okita +13 more
2025Future Oncology5 citations Open access
Semantic Scholar
Efficacy and safety of fruquintinib in patients with refractory metastatic colorectal cancer: a FRESCO-2 subgroup analysis of patients enrolled in Japan
D. Kotani, T. Yoshino, T. Masuishi, Y. Sunakawa +14 more
2025International Journal of Clinical Oncology5 citations Open access
Semantic Scholar
Impact of immune checkpoint inhibitors on survival outcomes in advanced gastric cancer in Japan: A real‐world analysis
T. Kadono, S. Iwasa, T. Hirose, H. Hirano +4 more
2024Cancer Medicine5 citations Open access
Semantic Scholar
Sex differences in toxicities and survival outcomes among Japanese patients with Stage III colorectal cancer receiving adjuvant fluoropyrimidine monotherapy: A pooled analysis of 4 randomized controlled trials (JCOG2310A).
H. Hirano, K. Kataoka, Toshifumi Yamaguchi, A. Wagner +16 more
2024European Journal of Cancer5 citations
Semantic Scholar
Definitive S-1/mitomycin-C chemoradiotherapy for stage II/III anal canal squamous cell carcinoma: a phase I/II dose-finding and single-arm confirmatory study (JCOG0903)
Yoshinori Ito, T. Hamaguchi, A. Takashima, J. Mizusawa +19 more
2023International Journal of Clinical Oncology5 citations
Semantic Scholar
Renal impairment as a risk factor for trifluridine/tipiracil-induced adverse events in metastatic colorectal cancer patients from the REGOTAS study
Mamiko Shiroyama, S. Fukuoka, T. Masuishi, A. Takashima +7 more
2023Scientific Reports5 citations Open access
Semantic Scholar
Abstract 7148: Exploratory biomarker analysis of trastuzumab deruxtecan (T-DXd) treatment for HER2-positive (HER2+) metastatic colorectal cancer (mCRC) in DESTINY-CRC02 (DC-02)
S. Siena, K. Raghav, A. Takashima, T. Kato +19 more
2025Cancer Research4 citations
Semantic Scholar
Localized colorectal cancer database integrating 4 randomized controlled trials; (JCOG2310A).
K. Kataoka, Akira Ouchi, Y. Suwa, H. Hirano +16 more
2024European Journal of Surgical Oncology4 citations
Semantic Scholar
Immunogenicity after vaccination of COVID-19 vaccines in patients with cancer: a prospective, single center, observational study
Katsuya Yuki, T. Yoshida, A. Takashima, K. Yonemori +9 more
2024International Journal of Clinical Oncology4 citations Open access
Semantic Scholar
Real-world treatment costs of first-line treatment for metastatic colorectal cancer: a survey of the JCOG colorectal cancer study group.
A. Takashima, M. Ishiguro, K. Sasaki, R. Machida +21 more
2024Japanese Journal of Clinical Oncology4 citations
Semantic Scholar
Utility of circulating tumour DNA for prognosis and prediction of therapeutic effect in locally recurrent rectal cancer: study protocol for a multi-institutional, prospective observational study (JCOG1801A1, CAP-LR study)
T. Hashimoto, Y. Tsukada, M. Ito, K. Kanato +5 more
2023BMJ Open4 citations Open access
Semantic Scholar
The impact of claudin-18.2 expression in patients with advanced gastric cancer treated with nivolumab.
T. Kadono, H. Shoji, H. Hirano, N. Okita +3 more
2023Journal of Clinical Oncology4 citations
Semantic Scholar
Role of plasma angiogenesis factors in the efficacy of first‐line chemotherapy combined with biologics in RAS wild‐type metastatic colorectal cancer: Results from the GI‐SCREEN CRC‐Ukit study
S. Yuki, K. Yamazaki, Y. Sunakawa, H. Taniguchi +17 more
2023Cancer Medicine4 citations Open access
Semantic Scholar
A safety trial of antibiotic fecal microbiota transplantation for esophageal and gastric cancer patients treated with immune checkpoint inhibitors (Biorich2 trial).
Y. Yoshinami, H. Shoji, N. Okita, H. Takamaru +10 more
2025Journal of Clinical Oncology3 citations
Semantic Scholar
Exploring novel therapeutic targets in small bowel adenocarcinoma: insights from claudin 18.2, nectin-4, and HER3 expression analysis
H. Fujii, H. Shoji, H. Hirano, T. Hirose +3 more
2025ESMO Open3 citations Open access
Semantic Scholar
CRP and soluble CTLA4 are determinants of anti-PD1 resistance in gastrointestinal cancer.
K. Oshima, H. Shoji, N. Boku, H. Hirano +4 more
2024American Journal of Cancer Research3 citations Open access
Semantic Scholar
Preoperative docetaxel, cisplatin, and 5-fluorouracil for resectable locally advanced esophageal and esophagogastric junctional adenocarcinoma
T. Hirose, S. Yamamoto, Y. Honma, Kazuki Yokoyama +10 more
2024Esophagus3 citations Open access
Semantic Scholar
Sidedness-Dependent Prognostic Impact of Gene Alterations in Metastatic Colorectal Cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN)
T. Kajiwara, T. Nishina, Riu Yamashita, Yoshiaki Nakamura +12 more
2023Cancers3 citations Open access
Semantic Scholar
Association Between Immune‐Related Adverse Events and Treatment Outcomes in Advanced Gastric Cancer Patients Receiving Nivolumab Plus Chemotherapy: A Retrospective Study
Kazumasa Yamamoto, H. Hirano, T. Hirose, H. Shoji +3 more
2025Cancer Medicine2 citations Open access
Semantic Scholar
Clinicopathological and molecular features of claudin-18 isoform 2 expression in patients with colorectal cancer: a single-center retrospective study
S. Takamizawa, H. Hirano, A. Takashima, H. Shoji +7 more
2024Therapeutic Advances in Medical Oncology2 citations Open access
Semantic Scholar
Geriatric assessment and management with question prompt list using a web-based application for elderly patients with cancer to communicate aging-related concerns: A randomized clinical trial (J-SUPPORT 2101 study).
Ayumu Matsuoka, M. Fujimori, N. Boku, A. Takashima +16 more
2024Journal of Clinical Oncology2 citations Open access
Semantic Scholar
Safety and efficacy of ONO-4578 plus nivolumab in metastatic colorectal cancer.
A. Kawazoe, A. Takashima, H. Matsuoka, Y. Hamamoto +8 more
2024Journal of Clinical Oncology2 citations Open access
Semantic Scholar
A retrospective analysis of the prognostic impact of KRAS G12D mutation in patients with RAS-mutated metastatic colorectal cancer.
T. Hirose, Kunihito Matsuguma, H. Hirano, N. Okita +3 more
2024Journal of Clinical Oncology2 citations
Semantic Scholar
A randomized phase II study comparing preoperative mFOLFOX6 versus FOLFOXIRI for locally advanced colon cancer: JCOG2006.
T. Hashimoto, S. Maruyama, Y. Takii, J. Mizusawa +6 more
2023Future Oncology2 citations
Semantic Scholar
Prognostic Impact of Claudin18.2 and TROP2 Expression in Advanced Gastric Cancer Treated With Nivolumab
Takahito Awatsu, T. Kadono, H. Shoji, T. Hirose +5 more
2026Anticancer Research1 citations
Semantic Scholar
Prognostic Role of Pretreatment Nutritional and Inflammatory Status in Unresectable Metastatic Colorectal Cancer: Supplementary Analysis of JCOG1007.
Taichi Horino, K. Komori, Y. Ishikawa, K. Kataoka +16 more
2026Annals of Surgical Oncology1 citations
Semantic Scholar
Comparison of first-line cetuximab and panitumumab plus doublet chemotherapies for left-sided colorectal cancer: a multicenter real-world observational study by the Japanese Society for Cancer of the Colon and Rectum.
Ryosuke Kawagoe, Toshikazu Moriwaki, K. Yamazaki, H. Yukami +22 more
2026International Journal of Clinical Oncology1 citations
Semantic Scholar
Predictive factors for early mortality after regorafenib or trifluridine/tipiracil initiation in metastatic colorectal cancer
T. Masuishi, S. Fukuoka, A. Takashima, Y. Kumekawa +3 more
2026The Oncologist1 citations Open access
Semantic Scholar
POD1UM-303/INTERAACT2 subgroup analyses and impact of delayed retifanlimab treatment on outcomes in patients with squamous cell carcinoma of the anal canal (SCAC).
M. Fakih, Rebecca Muirhead, A. Scott, M. Narang +16 more
2025Journal of Clinical Oncology1 citations
Semantic Scholar
Impact of prior nivolumab use on the efficacy of second-line taxane-based chemotherapy in advanced gastric or esophagogastric junction adenocarcinoma.
Momoko Sano, T. Hirose, S. Yamaguchi, H. Hirano +4 more
2025Journal of Clinical Oncology1 citations Open access
Semantic Scholar

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H. Hirano — researcher profile on SciRah
H. Shoji×13
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H. Shoji — researcher profile on SciRah
Y. Kanemitsu×13
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K. Kato — researcher profile on SciRah

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J. Mizusawa — researcher profile on SciRah