Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Melanie J. Shears · SciRah

Researcher profile · Semantic Scholar

Melanie J. Shears

Share profile

Melanie J. Shears — researcher profile on SciRah

h-index: 17
Works: 48
Citations: 1,359

Most-cited papers

Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics
Kristian E. Swearingen, S. Lindner, Lirong Shi, Melanie J. Shears +7 more
2016PLoS Pathogens177 citations Open access
Semantic Scholar
Lipid Profile Remodeling in Response to Nitrogen Deprivation in the Microalgae Chlorella sp. (Trebouxiophyceae) and Nannochloropsis sp. (Eustigmatophyceae)
Gregory J. O. Martin, D. Hill, I. Olmstead, Amanda Bergamin +6 more
2014PLoS ONE144 citations Open access
Semantic Scholar
Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression
Yining Zhu, Ruochen Shen, Ivan Vuong, Rebekah A. Reynolds +8 more
2022Nature Communications127 citations Open access
Semantic Scholar
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites
Cyrille Y. Botté, Yoshiki Yamaryo-Botté, T. Rupasinghe, Kylie A. Mullin +9 more
2013Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites
S. Lindner, Kristian E. Swearingen, Melanie J. Shears, M. P. Walker +6 more
2019Nature Communications120 citations Open access
Semantic Scholar
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity
Yining Zhu, Jing-Yao Ma, Ruochen Shen, Jinghan Lin +26 more
2023Nature Biomedical Engineering96 citations Open access
Semantic Scholar
Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts.
Melanie J. Shears, Cyrille Y. Botté, G. McFadden
2015Molecular and biochemical parasitology (Print)92 citations Open access
Semantic Scholar
Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase
Souad Amiar, J. MacRae, D. Callahan, D. Dubois +8 more
2016PLoS Pathogens69 citations Open access
Semantic Scholar
Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling.
Souad Amiar, Nicholas J. Katris, L. Berry, Sheena Dass +8 more
2020Cell Reports52 citations Open access
Semantic Scholar
Alpha-v–containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP
Kirsten Dundas, Melanie J. Shears, Yi Sun, Christine S. Hopp +6 more
2018Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria
Melanie J. Shears, R. Nirujogi, Kristian E. Swearingen, S. Renuse +5 more
2019bioRxiv37 citations Open access
Semantic Scholar
Important Extracellular Interactions between Plasmodium Sporozoites and Host Cells Required for Infection.
Kirsten Dundas, Melanie J. Shears, Photini Sinnis, Gavin J. Wright
2018Trends in Parasitology35 citations Open access
Semantic Scholar
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
Sachel Mok, Tomas Yeo, Davin Hong, Melanie J. Shears +20 more
2023bioRxiv34 citations Open access
Semantic Scholar
Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast
Melanie J. Shears, J. MacRae, Vanessa Mollard, C. Goodman +6 more
2016Cellular Microbiology32 citations Open access
Semantic Scholar
O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites
Giulia Bandini, Deborah R. Leon, Carolin M Hoppe, Yue Zhang +6 more
2018Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters
K. McLean, J. Straimer, Christine S. Hopp, Joel Vega-Rodríguez +12 more
2019Scientific Reports23 citations Open access
Semantic Scholar
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes
Camila Marques-da-Silva, Barun Poudel, R. Baptista, Kristen Peissig +10 more
2023Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein
Cherrelle Dacon, Re’em Moskovitz, Kristian E. Swearingen, Lais da Silva Pereira +43 more
2025Science17 citations Open access
Semantic Scholar
Cryopreserved Sporozoites with and without the Glycolipid Adjuvant 7DW8-5 Protect in Prime-and-Trap Malaria Vaccination.
Felicia N. Watson, Melanie J. Shears, Jokichi Matsubara, Anya C. Kalata +8 more
2022American Journal of Tropical Medicine and Hygiene16 citations Open access
Semantic Scholar
Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites
S. Chakravarty, Melanie J. Shears, E. James, U. Rai +6 more
2022Malaria Journal10 citations Open access
Semantic Scholar
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine
Zachary MacMillen, Kiara Hatzakis, Adrian C Simpson, Melanie J. Shears +8 more
2024npj Vaccines9 citations Open access
Semantic Scholar
Androgens inhibit protective CD8+ T cell responses against pre-erythrocytic malaria parasites in mice
C. Duncombe, N. Sen, Felicia N. Watson, Alen S. Poehlman +9 more
2025Nature Communications7 citations Open access
Semantic Scholar
Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression
Yining Zhu, Ruochen Shen, Ivan Vuong, Rebekah A. Reynolds +8 more
20226 citations Open access
Semantic Scholar
Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models
Melanie J. Shears, A. Seilie, B. Kim lee Sim, S. Hoffman +1 more
2020Malaria Journal6 citations Open access
Semantic Scholar
Direct quantification of single red blood cell hemoglobin concentration with multiphoton microscopy.
Andrew T. Francis, Melanie J. Shears, S. Murphy, Dan Fu
2020Analytical Chemistry5 citations
Semantic Scholar
Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria
Felicia N. Watson, Melanie J. Shears, Anya C. Kalata, C. Duncombe +11 more
2024Scientific Reports4 citations Open access
Semantic Scholar
More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
Naveen Yadav, C. Parthiban, Zachary P. Billman, B. Stone +10 more
2023iScience4 citations Open access
Semantic Scholar
Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria
Felicia N. Watson, Melanie J. Shears, Anya C. Kalata, C. Duncombe +11 more
2023Research Square4 citations Open access
Semantic Scholar
Generation of Transgenic Human Malaria Parasites With Strong Fluorescence in the Transmission Stages
K. McLean, J. Straimer, Christine S. Hopp, Joel Vega-Rodríguez +10 more
2018bioRxiv4 citations Open access
Semantic Scholar
Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research
Melanie J. Shears, Rebekah A. Reynolds, C. Duncombe, Felicia N. Watson +7 more
2023Malaria Journal3 citations Open access
Semantic Scholar
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine
Zachary MacMillen, Kiara Hatzakis, Adrian C Simpson, Melanie J. Shears +8 more
2023bioRxiv3 citations Open access
Semantic Scholar
Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver
Camila Marques-da-Silva, Barun Poudel, R. Baptista, Kristen Peissig +10 more
2021bioRxiv3 citations Open access
Semantic Scholar
O-fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites
Giulia Bandini, Deborah R. Leon, Carolin M Hoppe, Yue Zhang +6 more
2018bioRxiv3 citations Open access
Semantic Scholar
Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates
Melanie J. Shears, Felicia N. Watson, B. Stone, Irene Cruz Talavera +6 more
2023Vaccine2 citations Open access
Semantic Scholar
Vancomycin improves Plasmodium yoelii malaria parasite in vitro liver stage cultures by controlling Elizabethkingia anophelis, a bacterium in the microbiome of lab-reared Anopheles mosquitoes
Melanie J. Shears, S. Murphy
2020Molecular and biochemical parasitology (Print)2 citations Open access
Semantic Scholar
Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling
Souad Amiar, Nicholas J. Katris, L. Berry, Sheena Dass +7 more
2019bioRxiv2 citations Open access
Semantic Scholar
Drivers of complexity in ecosystem restoration
E. Waddell, B. Woodcock, James A. Harris, Kirsty J. Park +17 more
2026Journal of Applied Ecology1 citations Open access
Semantic Scholar
Identification of genetic markers of quinine partial resistance in Plasmodium falciparum
Mariko Kanai, Sachel Mok, Tomas Yeo, Melanie J. Shears +27 more
2026Nature Microbiology1 citations Open access
Semantic Scholar
Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54×Cam3.II P. falciparum genetic cross
Mariko Kanai, Sachel Mok, Tomas Yeo, Melanie J. Shears +23 more
2024bioRxiv1 citations Open access
Semantic Scholar
Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice
Felicia N. Watson, C. Duncombe, Anya C. Kalata, Ethan Conrad +6 more
2022Biomolecules1 citations Open access
Semantic Scholar
Extensive Transcriptional and Translational Regulation Occur During the Maturation of Malaria Parasite Sporozoites
S. Lindner, Kristian E. Swearingen, Melanie J. Shears, M. P. Walker +6 more
20191 citations Open access
Semantic Scholar
A prime-and-trap vaccination strategy to evaluate minimal requirements for malaria liver stage protection in mice
Felicia N. Watson, Rebekah A. Reynolds, Anya C. Kalata, Melanie J. Shears +1 more
2026Malaria Journal0 citations Open access
Semantic Scholar
Host biological sex directs immune control of the Plasmodium parasite liver stage in mice
C. Duncombe, Alen S. Poehlman, Ethan Conrad, N. Sen +10 more
2026Frontiers in Immunology0 citations Open access
Semantic Scholar
Drivers of invertebrate community assembly during ecosystem restoration
Samuel P. Rogerson, E. Waddell, Kirsty J. Park, E. Fuentes-Montemayor +9 more
2026Restoration Ecology0 citations Open access
Semantic Scholar
Differential sex-specific immune responses following Prime-and-Trap vaccination alters protection against malaria in mice
C. Duncombe, Felicia N. Watson, Anya C. Kalata, Melanie J. Shears +1 more
2022Journal of Immunology0 citations
Semantic Scholar
Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites
S. Chakravarty, Melanie J. Shears, E. James, U. Rai +6 more
2022Malaria Journal0 citations Open access
Semantic Scholar
Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites
S. Lindner, Kristian E. Swearingen, Melanie J. Shears, A. Sebastian +8 more
2022Nature Communications0 citations Open access
Semantic Scholar
Exploring how fatty acids synthesized by malaria parasites are incorporated into lipids: Characterization of the Plasmodium apicoplast glycerol-3-phosphate acyltransferase
Melanie J. Shears
20150 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

S. Murphy×21
Invite
S. Murphy — researcher profile on SciRah
Photini Sinnis×15
Invite
Photini Sinnis — researcher profile on SciRah
Felicia N. Watson×12
Invite
Felicia N. Watson — researcher profile on SciRah
Anya C. Kalata×9
Invite
Anya C. Kalata — researcher profile on SciRah

Cyrille Y. Botté

×7

Invite

Cyrille Y. Botté — researcher profile on SciRah

Invite

A. Seilie — researcher profile on SciRah

Invite

C. Duncombe — researcher profile on SciRah

Kristian E. Swearingen×6

Invite

Kristian E. Swearingen — researcher profile on SciRah

Invite

G. McFadden — researcher profile on SciRah

Invite

S. Hoffman — researcher profile on SciRah

S. Chakravarty×6

Invite

S. Chakravarty — researcher profile on SciRah

Invite

G. Mlambo — researcher profile on SciRah