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G. Brinkmalm · SciRah

Researcher profile · Semantic Scholar

G. Brinkmalm

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G. Brinkmalm — researcher profile on SciRah

h-index: 45
Works: 204
Citations: 8,672

Most-cited papers

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts.
T. Karikari, T. Pascoal, N. Ashton, S. Janelidze +19 more
2020Lancet Neurology1,135 citations Open access
Semantic Scholar
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
N. Ashton, T. Pascoal, T. Karikari, A. Benedet +11 more
2021Acta Neuropathologica616 citations Open access
Semantic Scholar
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility
T. Karikari, N. Ashton, G. Brinkmalm, W. Brum +8 more
2022Nature Reviews Neurology299 citations
Semantic Scholar
Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
C. Cicognola, G. Brinkmalm, Jessica Wahlgren, E. Portelius +12 more
2018Acta Neuropathologica148 citations Open access
Semantic Scholar
Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies
L. Montoliu-Gaya, A. Benedet, C. Tissot, A. Vrillon +17 more
2023Nature Aging121 citations Open access
Semantic Scholar
Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis
T. Karikari, A. Emeršič, A. Vrillon, J. Lantero-Rodríguez +10 more
2020Alzheimer's & Dementia120 citations Open access
Semantic Scholar
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain
I. Alić, P. Goh, Aoife Murray, E. Portelius +39 more
2020bioRxiv119 citations Open access
Semantic Scholar
Synaptic proteins in CSF as potential novel biomarkers for prognosis in prodromal Alzheimer’s disease
F. Duits, G. Brinkmalm, C. Teunissen, A. Brinkmalm +4 more
2018Alzheimer's Research & Therapy107 citations Open access
Semantic Scholar
Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain.
G. Brinkmalm, W. Hong, Zemin Wang, Wen Liu +8 more
2019Brain : a journal of neurology97 citations Open access
Semantic Scholar
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology.
K. Blennow, Chun Chen, C. Cicognola, Kristin R. Wildsmith +15 more
2019Brain : a journal of neurology97 citations Open access
Semantic Scholar
A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimer's Disease
G. Brinkmalm, S. Sjödin, A. Simonsen, S. Hasselbalch +3 more
2018PROTEOMICS - Clinical Applications97 citations Open access
Semantic Scholar
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease
H. Kvartsberg, T. Lashley, C. Murray, G. Brinkmalm +5 more
2018Acta Neuropathologica79 citations Open access
Semantic Scholar
Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer’s and Parkinson’s disease
S. Sjödin, G. Brinkmalm, A. Öhrfelt, L. Parnetti +6 more
2019Alzheimer's Research & Therapy75 citations Open access
Semantic Scholar
Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's disease
J. Nilsson, J. Gobom, S. Sjödin, G. Brinkmalm +7 more
2021Alzheimer's & Dementia73 citations Open access
Semantic Scholar
CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease
J. Lantero-Rodríguez, L. Montoliu-Gaya, A. Benedet, A. Vrillon +17 more
2024Acta Neuropathologica66 citations Open access
Semantic Scholar
Update on biomarkers for amyloid pathology in Alzheimer's disease.
N. Ashton, M. Schöll, Kerstin Heurling, Eleni Gkanatsiou +6 more
2018Biomarkers in Medicine66 citations Open access
Semantic Scholar
In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds
Naoto Watamura, M. Foiani, S. Bez, M. Bourdenx +24 more
2024Nature Neuroscience61 citations Open access
Semantic Scholar
A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's disease.
Eleni Gkanatsiou, E. Portelius, C. Toomey, K. Blennow +3 more
2019Neuroscience Letters57 citations Open access
Semantic Scholar
Optimal blood tau species for the detection of Alzheimer’s disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study
L. Montoliu-Gaya, M. Alosco, E. Yhang, Y. Tripodis +32 more
2023Acta Neuropathologica54 citations Open access
Semantic Scholar
Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology
W. Michno, Sofie Nyström, Patrick Wehrli, T. Lashley +11 more
2019Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer’s disease continuum
J. Gobom, A. Benedet, N. Mattsson-Carlgren, L. Montoliu-Gaya +13 more
2022Molecular Neurodegeneration45 citations Open access
Semantic Scholar
P‐tau235: a novel biomarker for staging preclinical Alzheimer’s disease
J. Lantero-Rodríguez, A. Snellman, A. Benedet, M. Milà-Alomà +15 more
2021EMBO Molecular Medicine43 citations Open access
Semantic Scholar
Plasma tau biomarkers for biological staging of Alzheimer’s disease
L. Montoliu-Gaya, G. Salvadó, J. Therriault, J. Nilsson +15 more
2025Nature Aging40 citations Open access
Semantic Scholar
Decreased cerebrospinal fluid Aβ 38, 40, 42, and 43 levels in sporadic and hereditary cerebral amyloid angiopathy
A. D. de Kort, H. B. Kuiperij, Tainá M. Marques, Lieke Jäkel +18 more
2023Annals of Neurology37 citations Open access
Semantic Scholar
Tau protein profiling in tauopathies: a human brain study
J. Lantero-Rodríguez, Elena Camporesi, L. Montoliu-Gaya, J. Gobom +13 more
2024Molecular Neurodegeneration35 citations Open access
Semantic Scholar
Quantification of total apolipoprotein E and its isoforms in cerebrospinal fluid from patients with neurodegenerative diseases
K. Minta, G. Brinkmalm, S. Janelidze, S. Sjödin +6 more
2020Alzheimer's Research & Therapy35 citations Open access
Semantic Scholar
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology
Przemysław R. Kac, F. González-Ortiz, A. Emeršič, M. Dulewicz +29 more
2024Nature Communications33 citations Open access
Semantic Scholar
Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase
Bruno Becker, Faisal Hayat Nazir, G. Brinkmalm, Elena Camporesi +8 more
2018Molecular Neurodegeneration33 citations Open access
Semantic Scholar
Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury
K. Minta, G. Brinkmalm, F. Al Nimer, E. Thelin +7 more
2020Scientific Reports30 citations Open access
Semantic Scholar
Plasma ACE2 species are differentially altered in COVID‐19 patients
M. García-Ayllón, Ó. Moreno-Pérez, J. García-Arriaza, J. Ramos-Rincón +10 more
2021The FASEB Journal26 citations Open access
Semantic Scholar
Synthetic standard aided quantification and structural characterization of amyloid-beta glycopeptides enriched from cerebrospinal fluid of Alzheimer’s disease patients
J. Nilsson, G. Brinkmalm, S. Ramadan, Lisa Gilborne +7 more
2019Scientific Reports24 citations Open access
Semantic Scholar
Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer’s Disease
K. Minta, G. Brinkmalm, E. Portelius, P. Johansson +6 more
2020Journal of Alzheimer's Disease21 citations Open access
Semantic Scholar
Amyloid pathology and synaptic loss in pathological aging
Eleni Gkanatsiou, J. Nilsson, C. Toomey, A. Vrillon +7 more
2021Journal of Neurochemistry20 citations Open access
Semantic Scholar
Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
K. Höglund, N. Schussler, H. Kvartsberg, U. Smailović +10 more
2020Neurobiology of Disease20 citations Open access
Semantic Scholar
Genetic mapping of APP and amyloid-β biology modulation by trisomy 21
Paige Mumford, Justin L. Tosh, Silvia Anderle, Eleni Gkanatsiou Wikberg +13 more
2022Journal of Neuroscience19 citations Open access
Semantic Scholar
Fluid‐based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases
A. Brinkmalm, E. Portelius, G. Brinkmalm, Josef Pannee +4 more
2018Journal of Neurochemistry19 citations
Semantic Scholar
Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus
K. Minta, A. Jeppsson, G. Brinkmalm, E. Portelius +4 more
2021Fluids and Barriers of the CNS18 citations Open access
Semantic Scholar
Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer’s disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma
W. Michno, K. Blennow, H. Zetterberg, G. Brinkmalm
2021Journal of Neurochemistry17 citations Open access
Semantic Scholar
Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis.
I. López‐Font, Aitana Sogorb-Esteve, Míriam Javier-Torrent, G. Brinkmalm +11 more
2019Neurobiology of Disease17 citations Open access
Semantic Scholar
Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments
Marianne K. O. Grant, Maureen Handoko, M. Rozga, G. Brinkmalm +5 more
2019PLoS ONE17 citations Open access
Semantic Scholar
Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity
S. Schilling, Ajay Pradhan, A. Heesch, Andrea Helbig +8 more
2023Acta Neuropathologica Communications16 citations Open access
Semantic Scholar
Characterization of monomeric and soluble aggregated Aβ in Down’s syndrome and Alzheimer’s disease brains
Eleni Gkanatsiou, Charlotte Sahlin, E. Portelius, Malin Johannesson +9 more
2020Neuroscience Letters15 citations Open access
Semantic Scholar
Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer’s disease with APPdup and Down syndrome
Amal Kasri, Elena Camporesi, Eleni Gkanatsiou, Susana Boluda +16 more
2024Acta Neuropathologica14 citations Open access
Semantic Scholar
Alzheimer's Disease Biomarker Analysis Using Targeted Mass Spectrometry
J. Gobom, A. Brinkmalm, G. Brinkmalm, K. Blennow +1 more
2024Molecular & Cellular Proteomics14 citations Open access
Semantic Scholar
The presubiculum is preserved from neurodegenerative changes in Alzheimer’s disease
C. Murray, P. Gami-Patel, Eleni Gkanatsiou, G. Brinkmalm +10 more
2018Acta Neuropathologica Communications14 citations Open access
Semantic Scholar
Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology
Przemysław R. Kac, F. González-Ortiz, A. Emeršič, M. Dulewicz +28 more
2023medRxiv13 citations Open access
Semantic Scholar
Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients
M. P. Lennol, Irene Sánchez-Domínguez, I. Cuchillo-Ibáñez, Elena Camporesi +9 more
2022Alzheimer's Research & Therapy13 citations Open access
Semantic Scholar
Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage
C. Cicognola, Tugce Munise Satir, G. Brinkmalm, Irena Matečko-Burmann +6 more
2020Journal of Alzheimer's Disease13 citations Open access
Semantic Scholar
Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury.
K. Minta, G. Brinkmalm, E. Thelin, F. Al Nimer +7 more
2020Clinica chimica acta; international journal of clinical chemistry12 citations Open access
Semantic Scholar
Chemical traits of cerebral amyloid angiopathy in familial British‐, Danish‐, and non‐Alzheimerʼs dementias
W. Michno, Srinivas Koutarapu, Rafael Camacho, C. Toomey +11 more
2022Journal of Neurochemistry11 citations Open access
Semantic Scholar

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