H. Rupani

Most-cited papers

Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Eugenia Mustafa Sadia Alfie Ashraf Sherif Mohamed Basir Al Abaleke Abbas Abbasi Abbott Abdelaziz Abdelbadiee , E. Abaleke, M. Abbas, Sadia Abbasi +496 more
2021The Lancet289 citations Open access
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Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3–like protein 1
T. Hinks, T. Brown, L. Lau, H. Rupani +10 more
2016Journal of Allergy and Clinical Immunology170 citations Open access
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Eosinophils and tissue remodeling: relevance to airway disease.
S. Siddiqui, C. Bachert, L. Bjermer, K. Buchheit +6 more
2023Journal of Allergy and Clinical Immunology105 citations Open access
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Time for a Paradigm Shift.
H. Rupani
2021Chest85 citations
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A MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells
R. Martínez-Núñez, Victor P Bondanese, F. Louafi, Ana S. Francisco-Garcia +6 more
2014PLoS ONE74 citations Open access
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Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile.
H. Rupani, R. Martínez-Núñez, P. Dennison, L. Lau +6 more
2016American Journal of Respiratory and Critical Care Medicine64 citations Open access
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Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma
A. Singhania, H. Rupani, N. Jayasekera, S. Lumb +5 more
2017PLoS ONE56 citations Open access
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Using FeNO Measurement in Clinical Asthma Management.
H. Rupani, B. Kent
2021Chest51 citations
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Recent Insights into the Management of Inflammation in Asthma
H. Rupani, W. Fong, A. Kyyaly, R. Kurukulaaratchy
2021Journal of Inflammation Research34 citations Open access
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The 2025 British Society for Rheumatology management recommendations for ANCA-associated vasculitis
K. Biddle, Judith Jade, H. Wilson-Morkeh, M. Adikari +27 more
2025Rheumatology33 citations Open access
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Advanced Symptom Management System for Patients with Malignant Pleural Mesothelioma (ASyMSmeso): Mixed Methods Study
R. Maguire, J. Connaghan, A. Arber, N. Klepacz +9 more
2020Journal of Medical Internet Research32 citations Open access
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Comprehensive characterisation of difficult-to-treat asthma reveals near absence of T2-low status.
H. Rupani, M. A. Kyyaly, A. Azim, Rana Abadalkareen +9 more
2023Journal of Allergy and Clinical Immunology: In Practice31 citations Open access
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Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation
Ana S. Francisco-Garcia, E. M. Garrido-Martin, H. Rupani, L. Lau +3 more
2019Non-Coding RNA28 citations Open access
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Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma
A. Azim, B. Green, L. Lau, H. Rupani +3 more
2021Allergy. European Journal of Allergy and Clinical Immunology27 citations Open access
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An international consensus on the use of asthma biologics in pregnancy.
Jennifer Naftel, D. Jackson, M. Coleman, G. D'ancona +4 more
2024The Lancet Respiratory Medicine26 citations
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Genome-wide post-transcriptional dysregulation by microRNAs in human asthma as revealed by Frac-seq
R. Martinez-Nunez, H. Rupani, M. Platé, M. Niranjan +3 more
2017Journal of Immunology26 citations Open access
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Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
E. Khaleva, C. Brightling, T. Eiwegger, A. Altraja +73 more
2024European Respiratory Journal25 citations Open access
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Reframing remission in severe asthma: a conceptual framework for distinguishing disease activity versus damage.
C. Porsbjerg, H. Rupani, John D Brannan, S. Ueki +5 more
2025The Lancet Respiratory Medicine22 citations Open access
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Overcoming Barriers to Remission in Severe Eosinophilic Asthma: Two‐Year Real‐World Data With Benralizumab
D. J. Jackson, H. Burhan, H. Rupani, P. Pfeffer +11 more
2024Clinical and Experimental Allergy22 citations Open access
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Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care
L. Loewenthal, John Busby, Ronald McDowell, Thomas Brown +18 more
2023Thorax20 citations Open access
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Effects of obesity on response to asthma biologic treatment: Longitudinal data from the United Kingdom Severe Asthma Registry.
S. Gonem, C. Redmond, John Busby, Pujan H. Patel +19 more
2025Journal of Allergy and Clinical Immunology: In Practice19 citations Open access
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IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit
A. Hill, Jessica E. Donaldson, C. Blume, Natalie P. Smithers +9 more
2016Tissue Barriers18 citations Open access
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Therapeutic relevance of eosinophilic inflammation and airway viral interactions in severe asthma
H. Rupani, Willliam Busse, Peter H. Howarth, P. Bardin +3 more
2024Allergy. European Journal of Allergy and Clinical Immunology15 citations Open access
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Bringing the treatable traits approach to primary care asthma management
P. Pfeffer, H. Rupani, A. De Simoni
2023Frontiers in Allergy13 citations Open access
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Benralizumab treatment of severe asthma in pregnancy: a case series.
J. Naftel, C. Eames, S. Kerley, C. Whitfield +7 more
2023Journal of Allergy and Clinical Immunology: In Practice11 citations Open access
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Pregnancy, asthma and exacerbations: a population-based cohort
Bohee Lee, Ernie Wong, Tricia Tan, H. Rupani +1 more
2025European Respiratory Journal9 citations
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A simple and effective evidence-based approach to asthma management: ICS-formoterol reliever therapy
M. L. Levy, R. Beasley, B. Bostock, T. Capstick +8 more
2024The British journal of general practice : the journal of the Royal College of General Practitioners8 citations Open access
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Biologics in severe asthma: Which one, When and Where?
H. Rupani, A. Murphy, Katie Bluer, Charlotte Renwick +7 more
2021Clinical and Experimental Allergy8 citations
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Early and Sustained Efficacy of Depemokimab in Type 2 Asthma: A Pooled Analysis of the SWIFT-1/-2 Studies.
M. Wechsler, I. Pavord, R. Panettieri, Roland Buhl +10 more
2026Journal of Allergy and Clinical Immunology: In Practice7 citations Open access
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Long term clinical remission on biologics: an analysis of real-worl data from the UK severe asthma registry.
C. Redmond, John Busby, A. H. Mansur, M. Patel +4 more
2025Journal of Allergy and Clinical Immunology: In Practice7 citations Open access
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Greenhouse gas emissions associated with severe asthma care in the United Kingdom.
A. Wilkinson, M. Khezrian, L. Heaney, Soram Patel +6 more
2025Journal of Allergy and Clinical Immunology: In Practice7 citations Open access
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Measurement of FeNO in asthma: what the hospital doctor needs to know.
H. Rupani, A. Chauhan
2019British journal of hospital medicine7 citations
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Evaluation of telehealth support in an integrated respiratory clinic
L. Fox, E. Heiden, M. Chauhan, Jayne Longstaff +10 more
2022npj Primary Care Respiratory Medicine6 citations Open access
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Super-Responders to Severe Asthma Treatments: Defining a New Paradigm.
H. Rupani, M. Hew
2021Journal of Allergy and Clinical Immunology: In Practice6 citations Open access
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The VICTORY (Investigation of Inflammacheck to Measure Exhaled Breath Condensate Hydrogen Peroxide in Respiratory Conditions) Study: Protocol for a Cross-sectional Observational Study
L. Fox, J. Gates, R. De Vos, L. Wiffen +5 more
2020JMIR Research Protocols6 citations Open access
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Modern Innovative Solutions to Improve Outcomes in Asthma, Breathlessness, and Chronic Obstructive Pulmonary Disease (MISSION ABC): Protocol for a Mixed-Methods Study
E. Lanning, E. Heiden, J. Longstaff, C. Fogg +9 more
2019JMIR Research Protocols6 citations Open access
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Pre-biologic assessment of adherence in severe asthma and association with biologic continuation: a UK Severe Asthma Registry Study
Freda Yang, Ronald McDowell, John Busby, Anna Murphy +25 more
2025BMJ Open Respiratory Research5 citations Open access
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Exploring the long-term utility of remotely monitored FeNO suppression testing in severe asthma.
John Busby, J. Holmes, M. Almutairi, Irene Berrar-Torre +15 more
2025Journal of Allergy and Clinical Immunology: In Practice5 citations Open access
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Impact of comorbidities on EQ-5D quality-of-life index in severe asthma
P. Pfeffer, Thomas Brown, Rekha Chaudhuri, Shoaib Faruqi +11 more
2024Journal of Allergy and Clinical Immunology: Global5 citations Open access
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COVID-19 vaccination acceptance, safety and side-effects in European patients with severe asthma
A. Bossios, A. Bacon, K. Eger, D. Paróczai +34 more
2023ERJ Open Research5 citations Open access
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Inhaler recycling prevalence in a secondary care clinic in England
R. De Vos, H. Rupani, J. Longstaff, A. Hicks +4 more
20205 citations
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Clinical and economic burden of severe asthma with low blood eosinophil counts.
John Busby, S. Menon, Neil Martin, Joe Lipworth +13 more
2024Journal of Allergy and Clinical Immunology: In Practice4 citations Open access
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MISSION ABC: transforming respiratory care through one-stop multidisciplinary clinics – an observational study
E. Heiden, Jayne Longstaff, M. Chauhan, R. De Vos +11 more
2024BMJ Open4 citations Open access
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Validation and further insight into the International Severe Asthma Registry (ISAR) eosinophil gradient algorithm in the Wessex AsThma CoHort of difficult asthma (WATCH) using historical blood eosinophil counts and induced sputum
C. Barber, A. Azim, C. Newell, A. Kyyaly +4 more
2022Clinical and Experimental Allergy4 citations Open access
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LSC Abstract – Altered small RNA cargo in severe asthma exosomes
Ana S. Francisco-Garcia, R. Martínez-Núñez, H. Rupani, L. Lau +2 more
20164 citations
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Newly diagnosed eosinophilic granulomatosis with polyangiitis in patients on biologics for severe asthma- a multi-centre case series.
H. Rupani, A. Bansal, S. Sergejeva, A. Nanzer +21 more
2025Journal of Allergy and Clinical Immunology: In Practice3 citations Open access
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Real-world effectiveness of biologic therapies in severe asthma patients ineligible for phase 3 randomised controlled trials of biologics: an analysis from the UK Severe Asthma Registry
P. Pfeffer, J. Karaj, Thomas Brown, H. Burhan +9 more
2025ERJ Open Research3 citations Open access
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Preserved antibody responses to COVID-19 vaccination and lower odds of developing COVID-19 in adults with severe asthma.
H. Rupani, D. Edwards, R. Chaudhuri, S. Smith +9 more
2024Journal of Allergy and Clinical Immunology: In Practice3 citations Open access
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Blood Eosinophil and Neutrophil Categories Can Differentiate Adult Asthma Phenotypes.
H. Rupani, W. Teague
2023Journal of Allergy and Clinical Immunology: In Practice3 citations Open access
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FeNO testing for asthma diagnosis in primary care
J. Longstaff, M. Chauhan, R. De Vos, T. Brown +3 more
20203 citations
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