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X. Palomer · SciRah

Researcher profile · Semantic Scholar

X. Palomer

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X. Palomer — researcher profile on SciRah

h-index: 44
Works: 108
Citations: 6,318

Most-cited papers

Role of vitamin D in the pathogenesis of type 2 diabetes mellitus
X. Palomer, J. González-Clemente, F. Blanco-Vaca, D. Mauricio
2008Diabetes, obesity and metabolism585 citations Open access
Semantic Scholar
Palmitic and Oleic Acid: The Yin and Yang of Fatty Acids in Type 2 Diabetes Mellitus.
X. Palomer, J. Pizarro-Delgado, E. Barroso, M. Vázquez-Carrera
2017Trends in endocrinology and metabolism493 citations Open access
Semantic Scholar
Oleate Reverses Palmitate-induced Insulin Resistance and Inflammation in Skeletal Muscle Cells*
Teresa Coll, Elena Eyre, R. Rodríguez-Calvo, X. Palomer +4 more
2008Journal of Biological Chemistry344 citations Open access
Semantic Scholar
An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy.
X. Palomer, Laia Salvadó, E. Barroso, M. Vázquez-Carrera
2013International Journal of Cardiology282 citations
Semantic Scholar
Targeting endoplasmic reticulum stress in insulin resistance.
Laia Salvadó, X. Palomer, E. Barroso, M. Vázquez-Carrera
2015Trends in endocrinology and metabolism207 citations
Semantic Scholar
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism
Laia Salvadó, Teresa Coll, A. M. Gómez-Foix, E. Salmerón +3 more
2013Diabetologia198 citations Open access
Semantic Scholar
The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells.
David Álvarez-Guardia, X. Palomer, Teresa Coll, M. Davidson +4 more
2010Cardiovascular Research188 citations Open access
Semantic Scholar
SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation
X. Palomer, M. Silvia Román-Azcona, J. Pizarro-Delgado, A. Planavila +11 more
2020Signal Transduction and Targeted Therapy179 citations Open access
Semantic Scholar
TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.
X. Palomer, David Álvarez-Guardia, R. Rodríguez-Calvo, Teresa Coll +5 more
2009Cardiovascular Research170 citations
Semantic Scholar
The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.
E. Barroso, R. Rodríguez-Calvo, L. Serrano-Marco, A. Astudillo +3 more
2011Endocrinology151 citations Open access
Semantic Scholar
Palmitate-Mediated Downregulation of Peroxisome Proliferator–Activated Receptor-γ Coactivator 1α in Skeletal Muscle Cells Involves MEK1/2 and Nuclear Factor-κB Activation
Teresa Coll, M. Jové, R. Rodríguez-Calvo, Elena Eyre +5 more
2006Diabetes141 citations Open access
Semantic Scholar
Activation of Peroxisome Proliferator–Activated Receptor β/δ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-κB Activity via Extracellular Signal–Related Kinase 1/2
R. Rodríguez-Calvo, Lucía Serrano, Teresa Coll, N. Moullan +7 more
2008Diabetes132 citations Open access
Semantic Scholar
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease
M. Zarei, E. Barroso, X. Palomer, Jianli Dai +14 more
2017Molecular Metabolism103 citations Open access
Semantic Scholar
PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism
Laia Salvadó, E. Barroso, A. M. Gómez-Foix, X. Palomer +3 more
2014Diabetologia98 citations
Semantic Scholar
Emerging Actors in Diabetic Cardiomyopathy: Heartbreaker Biomarkers or Therapeutic Targets?
X. Palomer, J. Pizarro-Delgado, M. Vázquez-Carrera
2018TIPS - Trends in Pharmacological Sciences92 citations Open access
Semantic Scholar
Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
Teresa Coll, David Álvarez-Guardia, E. Barroso, A. M. Gómez-Foix +3 more
2010Endocrinology92 citations
Semantic Scholar
PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
X. Palomer, E. Barroso, J. Pizarro-Delgado, Lucía Peña +5 more
2018International Journal of Molecular Sciences91 citations Open access
Semantic Scholar
PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.
David Álvarez-Guardia, X. Palomer, Teresa Coll, Lucía Serrano +7 more
2011Biochimica et Biophysica Acta88 citations
Semantic Scholar
Targeting FGF21 for the Treatment of Nonalcoholic Steatohepatitis.
M. Zarei, J. Pizarro-Delgado, E. Barroso, X. Palomer +1 more
2020TIPS - Trends in Pharmacological Sciences83 citations Open access
Semantic Scholar
The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells
L. Serrano-Marco, E. Barroso, I. El Kochairi, X. Palomer +3 more
2012Diabetologia80 citations Open access
Semantic Scholar
Activation of Peroxisome Proliferator–Activated Receptor-β/-δ (PPAR-β/-δ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6–Stimulated Adipocytes
L. Serrano-Marco, R. Rodríguez-Calvo, I. El Kochairi, X. Palomer +3 more
2011Diabetes79 citations Open access
Semantic Scholar
GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.
David Aguilar-Recarte, E. Barroso, A. Gumà, J. Pizarro-Delgado +5 more
2020Cell Reports76 citations Open access
Semantic Scholar
Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation.
Teresa Coll, M. Jové, R. Rodríguez-Calvo, Elena Eyre +5 more
2006Diabetes76 citations
Semantic Scholar
GADD45A: With or without you
X. Palomer, Jesús M. Salvador, C. Griñán-Ferré, E. Barroso +2 more
2024Medicinal research reviews (Print)74 citations Open access
Semantic Scholar
The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1.
E. Barroso, Elena Eyre, X. Palomer, M. Vázquez-Carrera
2011Biochemical Pharmacology71 citations
Semantic Scholar
Atorvastatin prevents carbohydrate response element binding protein activation in the fructose‐fed rat by activating protein kinase A
R. Rodríguez-Calvo, E. Barroso, Lucía Serrano, Teresa Coll +5 more
2009Hepatology69 citations
Semantic Scholar
Peroxisome proliferator-activated receptor (PPAR) beta/delta: a new potential therapeutic target for the treatment of metabolic syndrome.
Teresa Coll, Ricardo Rodrïguez-Calvo, E. Barroso, Lucía Serrano +3 more
2009Current Molecular Pharmacology68 citations
Semantic Scholar
PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells.
X. Palomer, Eva Capdevila-Busquets, Gaia Botteri, Laia Salvadó +5 more
2014International Journal of Cardiology66 citations Open access
Semantic Scholar
The Effects of Liposuction Removal of Subcutaneous Abdominal Fat on Lipid Metabolism are Independent of Insulin Sensitivity in Normal-Overweight Individuals
J. Ybarra, F. Blanco-Vaca, Sandra Férnandez, A. Castellví +6 more
2008Obesity Surgery66 citations
Semantic Scholar
Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells.
Teresa Coll, X. Palomer, F. Blanco-Vaca, J. Escolà-Gil +3 more
2010Endocrinology62 citations
Semantic Scholar
Increased hepatic gluconeogenesis and type 2 diabetes mellitus.
E. Barroso, Javier Jurado-Aguilar, W. Wahli, X. Palomer +1 more
2024Trends in endocrinology and metabolism61 citations
Semantic Scholar
TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes.
L. Serrano-Marco, M. Chacón, E. Maymó-Masip, E. Barroso +7 more
2012Biochimica et Biophysica Acta55 citations
Semantic Scholar
PGC-1α Induces Mitochondrial and Myokine Transcriptional Programs and Lipid Droplet and Glycogen Accumulation in Cultured Human Skeletal Muscle Cells
Emma Mormeneo, C. Jimenez-Mallebrera, X. Palomer, V. De Nigris +6 more
2012PLoS ONE53 citations Open access
Semantic Scholar
Dietary phytosterols modulate T-helper immune response but do not induce apparent anti-inflammatory effects in a mouse model of acute, aseptic inflammation.
L. Calpe-Berdiel, J. Escolà-Gil, S. Benítez, Cristina Bancells +3 more
2007Life Science53 citations
Semantic Scholar
Antisense down-regulation of strawberry endo-β-(1,4)-glucanase genes does not prevent fruit softening during ripening
X. Palomer, I. Llop-Tous, M. Vendrell, F. Krens +4 more
200650 citations Open access
Semantic Scholar
PPARβ/δ and lipid metabolism in the heart.
X. Palomer, E. Barroso, M. Zarei, Gaia Botteri +1 more
2016Biochimica et Biophysica Acta49 citations
Semantic Scholar
Targeting AMPK as a potential treatment for hepatic fibrosis in MASLD.
X. Palomer, Jue-Rui Wang, Claudia Escalona, Siyuan Wu +2 more
2025TIPS - Trends in Pharmacological Sciences48 citations
Semantic Scholar
Peroxisome Proliferator-Activated Receptor (PPAR)β /δ: A New Potential Therapeutic Target for the Treatment of Metabolic Syndrome
Teresa Coll, R. Rodríguez-Calvo, E. Barroso, Lucía Serrano +3 more
200948 citations
Semantic Scholar
GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway.
Javier Jurado-Aguilar, E. Barroso, Maribel Bernard, Meijian Zhang +6 more
2024Metabolism: Clinical and Experimental46 citations Open access
Semantic Scholar
miR-146a targets Fos expression in human cardiac cells
X. Palomer, Eva Capdevila-Busquets, Gaia Botteri, M. Davidson +7 more
2015Disease Models & Mechanisms46 citations Open access
Semantic Scholar
Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.
David Aguilar-Recarte, E. Barroso, X. Palomer, W. Wahli +1 more
2022Trends in endocrinology and metabolism44 citations Open access
Semantic Scholar
Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy.
X. Palomer, David Aguilar-Recarte, R. García, J. Nistal +1 more
2021Trends in Molecular Medicine44 citations Open access
Semantic Scholar
Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus
Laia Salvadó, L. Serrano-Marco, E. Barroso, X. Palomer +1 more
2012Expert opinion on therapeutic targets43 citations
Semantic Scholar
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
E. Barroso, R. Rodríguez-Rodríguez, M. Zarei, Javier Pizarro-Degado +4 more
2020Cell Communication and Signaling42 citations Open access
Semantic Scholar
Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity
M. García-Ramírez, C. Hernández, X. Palomer, M. Vázquez-Carrera +1 more
2016Acta Diabetologica42 citations
Semantic Scholar
Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.
E. Barroso, J. del Valle, David Porquet, Ana M. Vieira Santos +11 more
2013Biochimica et Biophysica Acta42 citations Open access
Semantic Scholar
A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.
David Aguilar-Recarte, E. Barroso, Meijian Zhang, P. Rada +6 more
2022Pharmacological Research40 citations Open access
Semantic Scholar
Revealing the role of Peroxisome Proliferator-Activated Receptor β/δ in nonalcoholic fatty liver disease.
M. Zarei, David Aguilar-Recarte, X. Palomer, M. Vázquez-Carrera
2020Metabolism: Clinical and Experimental39 citations Open access
Semantic Scholar
The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling.
Gaia Botteri, Laia Salvadó, A. Gumà, D. Hamilton +13 more
2018Metabolism: Clinical and Experimental37 citations Open access
Semantic Scholar
Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency
M. Zarei, E. Barroso, R. Leiva, Marta Barniol-Xicota +11 more
2016Diabetes37 citations Open access
Semantic Scholar

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