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P. Gual · SciRah

Researcher profile · Semantic Scholar

P. Gual

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P. Gual — researcher profile on SciRah

h-index: 47
Works: 136
Citations: 9,398

Most-cited papers

M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease
J. Wan, M. Benkdane, F. Teixeira-Clerc, S. Bonnafous +8 more
2014Hepatology492 citations Open access
Semantic Scholar
ER stress induces NLRP3 inflammasome activation and hepatocyte death
C. Lebeaupin, E. Proics, Chd de Bieville, D. Rousseau +14 more
2015Cell Death and Disease387 citations Open access
Semantic Scholar
Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients
Adeline Bertola, T. Ciucci, D. Rousseau, V. Bourlier +10 more
2012Diabetes370 citations Open access
Semantic Scholar
Hepatic Expression Patterns of Inflammatory and Immune Response Genes Associated with Obesity and NASH in Morbidly Obese Patients
Adeline Bertola, S. Bonnafous, R. Anty, S. Patouraux +8 more
2010PLoS ONE245 citations Open access
Semantic Scholar
Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients
Franck Chiappini, A. Coilly, H. Kadar, P. Gual +9 more
2017Scientific Reports230 citations Open access
Semantic Scholar
Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression
J. Barr, J. Caballería, I. Martínez-Arranz, A. Domínguez‐Díez +25 more
2012Journal of Proteome Research222 citations Open access
Semantic Scholar
Chronic Inflammation in Non-Alcoholic Steatohepatitis: Molecular Mechanisms and Therapeutic Strategies
C. Luci, Manon Bourinet, P. Leclère, R. Anty +1 more
2020Frontiers in Endocrinology181 citations Open access
Semantic Scholar
Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence by Osteopontin Production
D. Sawaki, G. Czibik, M. Pini, J. Ternacle +14 more
2018Circulation175 citations Open access
Semantic Scholar
Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.
M. Cerezo, Abdelali Lehraiki, Antoine Millet, Florian Rouaud +26 more
2016Cancer Cell157 citations Open access
Semantic Scholar
Liquid Chromatography−Mass Spectrometry-Based Parallel Metabolic Profiling of Human and Mouse Model Serum Reveals Putative Biomarkers Associated with the Progression of Nonalcoholic Fatty Liver Disease
J. Barr, M. Vazquez--Chantada, C. Alonso, Miriam Pérez-Cormenzana +16 more
2010Figshare157 citations Open access
Semantic Scholar
A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin‐18 for the diagnosis of non‐alcoholic steatohepatitis in morbidly obese patients
R. Anty, A. Iannelli, S. Patouraux, S. Bonnafous +11 more
2010Alimentary Pharmacology and Therapeutics148 citations Open access
Semantic Scholar
Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery.
R. Anty, S. Marjoux, A. Iannelli, S. Patouraux +11 more
2012Journal of Hepatology140 citations
Semantic Scholar
Endoplasmic reticulum-mitochondria miscommunication is an early and causal trigger of hepatic insulin resistance and steatosis.
Agathe Beaulant, M. Dia, B. Pillot, M. Chauvin +15 more
2022Journal of Hepatology138 citations Open access
Semantic Scholar
Autophagy and Non-Alcoholic Fatty Liver Disease
V. Lavallard, P. Gual
2014BioMed Research International126 citations Open access
Semantic Scholar
CD44 is a key player in non-alcoholic steatohepatitis.
S. Patouraux, D. Rousseau, S. Bonnafous, C. Lebeaupin +11 more
2017Journal of Hepatology120 citations
Semantic Scholar
C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients.
E. Zimmermann, R. Anty, J. Tordjman, A. Verrijken +11 more
2011Journal of Hepatology114 citations
Semantic Scholar
Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.
M. Cerezo, Abdelali Lehraiki, Antoine Millet, Florian Rouaud +26 more
2016Cancer Cell100 citations Open access
Semantic Scholar
Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice
Stéphanie Garcia, B. Dirat, Thomas Tognacci, N. Rochet +8 more
2013Science Translational Medicine87 citations
Semantic Scholar
The Osteopontin Level in Liver, Adipose Tissue and Serum Is Correlated with Fibrosis in Patients with Alcoholic Liver Disease
S. Patouraux, S. Bonnafous, C. Voican, R. Anty +12 more
2012PLoS ONE87 citations Open access
Semantic Scholar
Screening for therapeutic trials and treatment indication in clinical practice: MACK‐3, a new blood test for the diagnosis of fibrotic NASH
J. Boursier, R. Anty, L. Vonghia, Valérie Moal +19 more
2018Alimentary Pharmacology and Therapeutics80 citations Open access
Semantic Scholar
Autophagy, signaling and obesity.
V. Lavallard, A. Meijer, P. Codogno, P. Gual
2012Pharmacological Research80 citations
Semantic Scholar
Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice
C. Lebeaupin, Déborah Vallée, D. Rousseau, S. Patouraux +12 more
2018Hepatology79 citations
Semantic Scholar
Serum Markers of Hepatocyte Death and Apoptosis Are Non Invasive Biomarkers of Severe Fibrosis in Patients with Alcoholic Liver Disease
V. Lavallard, S. Bonnafous, S. Patouraux, M. Saint-Paul +5 more
2011PLoS ONE74 citations Open access
Semantic Scholar
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD.
Romain Donné, Maëva Saroul-Ainama, Pierre Cordier, A. Hammoutène +20 more
2022Developmental Cell71 citations Open access
Semantic Scholar
Autophagy in chronic liver diseases: the two faces of Janus.
P. Gual, H. Gilgenkrantz, S. Lotersztajn
2017American Journal of Physiology - Cell Physiology70 citations
Semantic Scholar
Low Levels of 25-Hydroxy Vitamin D are Independently Associated with the Risk of Bacterial Infection in Cirrhotic Patients
R. Anty, M. Tonohouan, Patricia Ferrari-Panaia, T. Piche +4 more
2014Clinical and Translational Gastroenterology64 citations Open access
Semantic Scholar
Natural Killer Cells and Type 1 Innate Lymphoid Cells Are New Actors in Non-alcoholic Fatty Liver Disease
C. Luci, Élodie Vieira, Thibaut Perchet, P. Gual +1 more
2019Frontiers in Immunology59 citations Open access
Semantic Scholar
Metabolic Fatty Liver Disease in Children: A Growing Public Health Problem
S. Le Garf, V. Négre, R. Anty, P. Gual
2021Biomedicines46 citations Open access
Semantic Scholar
Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice
S. Patouraux, D. Rousseau, A. Rubio, S. Bonnafous +7 more
2014Cell Death and Disease46 citations Open access
Semantic Scholar
Hemojuvelin: A New Link Between Obesity and Iron Homeostasis
N. Luciani, C. Brasse-Lagnel, Maura Poli, R. Anty +9 more
2011Obesity45 citations Open access
Semantic Scholar
Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1
Marion Seillier, L. Pouyet, P. N'guessan, Marie Nollet +18 more
2015EMBO Molecular Medicine44 citations Open access
Semantic Scholar
The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis
A. Sans, S. Bonnafous, D. Rousseau, S. Patouraux +12 more
2019Scientific Reports42 citations Open access
Semantic Scholar
Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation
Meghana Patel, W. Bernard, N. Milev, W. Cawthorn +18 more
2014Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver.
C. Canivet, S. Bonnafous, D. Rousseau, P. Leclère +9 more
2020Biochimica et Biophysica Acta - Molecular Basis of Disease37 citations Open access
Semantic Scholar
Roux-En Y Gastric Bypass Results in Long-Term Remission of Hepatocyte Apoptosis and Hepatic Histological Features of Non-alcoholic Steatohepatitis
A. Schneck, R. Anty, S. Patouraux, S. Bonnafous +8 more
2016Frontiers in Physiology37 citations Open access
Semantic Scholar
Body composition, anthropometrics, energy expenditure, systemic inflammation, in premenopausal women 1 year after laparoscopic Roux-en-Y gastric bypass
A. Iannelli, F. Martini, Anty Rodolphe, A. Schneck +4 more
2014Surgical Endoscopy37 citations
Semantic Scholar
Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction
D. Sawaki, Yan-Yan Zhang, A. Mohamadi, M. Pini +18 more
2023JCI Insight36 citations Open access
Semantic Scholar
Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease
M. Vazquez--Chantada, Aintzane González-Lahera, I. Martínez-Arranz, C. García-Monzón +28 more
2013Hepatology36 citations Open access
Semantic Scholar
Non-alcoholic steatohepatitis in morbidly obese patients.
A. Tran, P. Gual
2013Clinics And Research in Hepatology and Gastroenterology34 citations
Semantic Scholar
Severe Vitamin D Deficiency May be an Additional Cofactor for the Occurrence of Alcoholic Steatohepatitis.
R. Anty, C. Canivet, S. Patouraux, Patricia Ferrari-Panaia +6 more
2015Alcoholism: Clinical and Experimental Research31 citations
Semantic Scholar
Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.
C. Regazzetti, K. Dumas, S. Lacas-Gervais, Faustine Pastor +11 more
2015Endocrinology29 citations
Semantic Scholar
Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia
Céline Saint-Laurent, Stéphanie Garcia, Vincent Sarrazy, K. Dumas +7 more
2018PLoS ONE28 citations Open access
Semantic Scholar
Severe Vitamin D Deficiency Is Not Associated with Liver Damage in Morbidly Obese Patients
R. Anty, A. Hastier, C. Canivet, S. Patouraux +8 more
2016Obesity Surgery26 citations
Semantic Scholar
Baseline Anthropometric and Metabolic Parameters Correlate with Weight Loss in Women 1-Year After Laparoscopic Roux-En-Y Gastric Bypass
A. Sans, L. Bailly, R. Anty, Igor Sielezenef +4 more
2017Obesity Surgery24 citations
Semantic Scholar
Effects of sleeve gastrectomy in high fat diet-induced obese mice: respective role of reduced caloric intake, white adipose tissue inflammation and changes in adipose tissue and ectopic fat depots
A. Schneck, A. Iannelli, S. Patouraux, D. Rousseau +9 more
2014Surgical Endoscopy23 citations
Semantic Scholar
MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice
P. Leclère, D. Rousseau, S. Patouraux, Sophie Guérin +9 more
2020Scientific Reports22 citations Open access
Semantic Scholar
Therapeutic Physical Exercise Programs in the Context of NASH Cirrhosis and Liver Transplantation: A Systematic Review
M. Farrugia, S. Le Garf, Andréa Chierici, T. Piche +3 more
2023Metabolites19 citations Open access
Semantic Scholar
The mid-infrared spectroscopy: A novel non-invasive diagnostic tool for NASH diagnosis in severe obesity
R. Anty, Marie Morvan, M. Le Corvec, C. Canivet +14 more
2019JHEP Reports19 citations Open access
Semantic Scholar
Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE 1 α signaling
C. Lebeaupin, Déborah Vallée, D. Rousseau, S. Patouraux +12 more
201819 citations
Semantic Scholar
Immunoglobulin G4-associated autoimmune hepatitis may be found in Western countries.
C. Canivet, R. Anty, S. Patouraux, M. Saint-Paul +4 more
2016Digestive and Liver Disease19 citations
Semantic Scholar

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