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T. Pochapsky · SciRah

Researcher profile · Semantic Scholar

T. Pochapsky

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T. Pochapsky — researcher profile on SciRah

h-index: 34
Works: 152
Citations: 4,545

Most-cited papers

A soluble α-synuclein construct forms a dynamic tetramer
Wei Wang, Iva Perovic, J. Chittuluru, A. Kaganovich +16 more
2011Proceedings of the National Academy of Sciences of the United States of America465 citations Open access
Semantic Scholar
Mechanistic studies of two dioxygenases in the methionine salvage pathway of Klebsiella pneumoniae.
Yong Dai, T. Pochapsky, R. Abeles
2001Biochemistry127 citations
Semantic Scholar
Conformational Plasticity and Structure/Function Relationships in Cytochromes P450
T. Pochapsky, S. Kazanis, Marina Dang
2010Antioxidants and Redox Signaling123 citations Open access
Semantic Scholar
The dynamic structure of α-synuclein multimers.
Thomas Gurry, Orly Ullman, Charles K. Fisher, Iva Perovic +2 more
2013Journal of the American Chemical Society103 citations Open access
Semantic Scholar
Modeling and experiment yields the structure of acireductone dioxygenase from Klebsiella pneumoniae
T. Pochapsky, S. Pochapsky, Ting-Ting Ju, H. Mo +2 more
2002Nature Structural Biology82 citations
Semantic Scholar
The immediate-early ethylene response gene OsARD1 encodes an acireductone dioxygenase involved in recycling of the ethylene precursor S-adenosylmethionine.
M. Sauter, René Lorbiecke, Bo Ouyang, T. Pochapsky +1 more
2005The Plant Journal77 citations Open access
Semantic Scholar
A model for effector activity in a highly specific biological electron transfer complex: the cytochrome P450(cam)-putidaredoxin couple.
S. Pochapsky, T. Pochapsky, Julie W Wei
2003Biochemistry72 citations
Semantic Scholar
Intermolecular interactions characterized by nuclear Overhauser effects
H. Mo, T. Pochapsky
199771 citations
Semantic Scholar
The communication between the zinc and nickel sites in dimeric HypA: Metal recognition and pH sensing
R. Herbst, Iva Perovic, V. Martin-Diaconescu, K. O'Brien +4 more
2010Journal of the American Chemical Society53 citations Open access
Semantic Scholar
One protein, two enzymes revisited: a structural entropy switch interconverts the two isoforms of acireductone dioxygenase.
Ting-Ting Ju, R. Goldsmith, S. Chai, M. Maroney +2 more
2006Journal of Molecular Biology53 citations Open access
Semantic Scholar
XAS investigation of the structure and function of Ni in acireductone dioxygenase.
F. Al-Mjeni, Ting-Ting Ju, T. Pochapsky, M. Maroney
2002Biochemistry51 citations
Semantic Scholar
Substrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation Reactions*
Shengying Li, D. Tietz, F. Rutaganira, P. M. Kells +5 more
2012Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Acireductone Dioxygenase 1 (ARD1) Is an Effector of the Heterotrimeric G Protein β Subunit in Arabidopsis*
Erin J. Friedman, Helen X. Wang, Kun Jiang, Iva Perovic +6 more
2011Journal of Biological Chemistry45 citations Open access
Semantic Scholar
A refined model for the solution structure of oxidized putidaredoxin.
T. Pochapsky, N. Jain, M. Kuti, Teresa A. Lyons +1 more
1999Biochemistry44 citations
Semantic Scholar
Detection of substrate-dependent conformational changes in the P450 fold by nuclear magnetic resonance
Allison M. Colthart, D. Tietz, Yu-Hua Ni, J. Friedman +2 more
2016Scientific Reports42 citations Open access
Semantic Scholar
A functional proline switch in cytochrome P450cam.
Bo Ouyang, S. Pochapsky, Marina Dang, T. Pochapsky
2008Structure41 citations Open access
Semantic Scholar
The metal drives the chemistry: Dual functions of acireductone dioxygenase
A. Deshpande, T. Pochapsky, D. Ringe
2017Chemical Reviews40 citations Open access
Semantic Scholar
Solution NMR structure of putidaredoxin-cytochrome P450cam complex via a combined residual dipolar coupling-spin labeling approach suggests a role for Trp106 of putidaredoxin in complex formation
Wei Zhang, S. Pochapsky, T. Pochapsky, N. Jain
2008Journal of Molecular Biology39 citations Open access
Semantic Scholar
Metal-dependent function of a mammalian acireductone dioxygenase
A. Deshpande, K. Wagenpfeil, T. Pochapsky, G. Petsko +1 more
2016Biochemistry38 citations Open access
Semantic Scholar
Expression, Function of the Human Androgen-Responsive Gene AD11 in Prostate Cancer
Shane W. Oram, J. Ai, Gina M. Pagani, M. R. Hitchens +10 more
200738 citations Open access
Semantic Scholar
Rapid recycle (13)C',(15)N and (13)C,(13)C' heteronuclear and homonuclear multiple quantum coherence detection for resonance assignments in paramagnetic proteins: example of Ni(2+)-containing acireductone dioxygenase.
M. Kostic, S. Pochapsky, T. Pochapsky
2002Journal of the American Chemical Society38 citations
Semantic Scholar
Characterization of metal binding in the active sites of acireductone dioxygenase isoforms from Klebsiella ATCC 8724.
S. Chai, Ting-Ting Ju, Marina Dang, R. Goldsmith +2 more
2008Biochemistry37 citations Open access
Semantic Scholar
A Refined Model for the Structure of Acireductone Dioxygenase from Klebsiella ATCC 8724 Incorporating Residual Dipolar Couplings
T. Pochapsky, S. Pochapsky, Ting-Ting Ju, C. Hoefler +1 more
2006Journal of Biomolecular NMR37 citations
Semantic Scholar
Analogs of 1-phosphonooxy-2,2-dihydroxy-3-oxo-5-(methylthio)pentane, an acyclic intermediate in the methionine salvage pathway: a new preparation and characterization of activity with E1 enolase/phosphatase from Klebsiella oxytoca.
Ya-Lin Zhang, Melissa H Heinsen, M. Kostic, Gina M. Pagani +5 more
2004Bioorganic & Medicinal Chemistry33 citations
Semantic Scholar
Unfolding a molecular trefoil derived from a zwitterionic metallopeptide to form self-assembled nanostructures
Ye Zhang, Ning Zhou, Jun-Feng Shi, S. Pochapsky +4 more
2015Nature Communications32 citations Open access
Semantic Scholar
Solution Structural Ensembles of Substrate-Free Cytochrome P450cam,
Eliana K. Asciutto, M. J. Young, J. Madura, S. Pochapsky +1 more
2012Biochemistry32 citations Open access
Semantic Scholar
Detection of a high-barrier conformational change in the active site of cytochrome P450cam upon binding of putidaredoxin.
Julie Y. Wei, T. Pochapsky, S. Pochapsky
2005Journal of the American Chemical Society32 citations
Semantic Scholar
Comparison of the complexes formed by cytochrome P450cam with cytochrome b5 and putidaredoxin, two effectors of camphor hydroxylase activity.
Lingyun Rui, S. Pochapsky, T. Pochapsky
2006Biochemistry31 citations Open access
Semantic Scholar
Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies
John B. Sanderson, S. De, Haiyang Jiang, Matteo Rovere +13 more
2020Brain Communications30 citations Open access
Semantic Scholar
Structural and dynamic implications of an effector-induced backbone amide cis-trans isomerization in cytochrome P450cam
Eliana K. Asciutto, J. Madura, S. Pochapsky, Bo Ouyang +1 more
2009Journal of Molecular Biology28 citations Open access
Semantic Scholar
Specific effects of potassium ion binding on wild-type and L358P cytochrome P450cam.
Bo Ouyang, S. Pochapsky, Gina M. Pagani, T. Pochapsky
2006Biochemistry28 citations Open access
Semantic Scholar
Expression and function of the human androgen-responsive gene ADI1 in prostate cancer.
Shane W. Oram, J. Ai, Gina M. Pagani, M. R. Hitchens +10 more
2007Neoplasia27 citations
Semantic Scholar
Redox-dependent conformational selection in a Cys4Fe2S2 ferredoxin.
T. Pochapsky, M. Kostic, N. Jain, R. Pejchal
2001Biochemistry26 citations
Semantic Scholar
A model for the solution structure of oxidized terpredoxin, a Fe2S2 ferredoxin from Pseudomonas.
H. Mo, S. Pochapsky, T. Pochapsky
1999Biochemistry26 citations
Semantic Scholar
Nuclear magnetic resonance as a tool in drug discovery, metabolism and disposition.
S. Pochapsky, T. Pochapsky
2001Current Topics in Medicinal Chemistry25 citations
Semantic Scholar
Experimentally restrained molecular dynamics simulations for characterizing the open states of cytochrome P450cam,
Eliana K. Asciutto, Marina Dang, S. Pochapsky, J. Madura +1 more
2011Biochemistry24 citations Open access
Semantic Scholar
Comparison of functional domains in vertebrate-type ferredoxins.
M. Kostic, S. Pochapsky, J. Obenauer, H. Mo +3 more
2002Biochemistry21 citations
Semantic Scholar
Redox-dependent dynamics in cytochrome P450cam
S. Pochapsky, Marina Dang, Bo Ouyang, Alana K. Simorellis +1 more
2009Biochemistry20 citations Open access
Semantic Scholar
NMR for Physical and Biological Scientists
T. Pochapsky, S. Pochapsky
200620 citations
Semantic Scholar
Thermodynamics of interactions between amino acid side chains: experimental differentiation of aromatic-aromatic, aromatic-aliphatic, and aliphatic-aliphatic side-chain interactions in water.
A. D. de Araújo, T. Pochapsky, B. Joughin
1999Biophysical Journal20 citations Open access
Semantic Scholar
What Your Crystal Structure Will Not Tell You about Enzyme Function
T. Pochapsky, S. Pochapsky
2019Accounts of Chemical Research19 citations Open access
Semantic Scholar
Solution conformations and dynamics of substrate-bound cytochrome P450 MycG
D. Tietz, L. Podust, D. Sherman, T. Pochapsky
2017Biochemistry19 citations Open access
Semantic Scholar
Hydrogen-deuterium exchange mass spectrometry for investigation of backbone dynamics of oxidized and reduced cytochrome P450cam.
Y. Hamuro, Kathleen S. Molnar, Stephen J. Coales, Bo Ouyang +2 more
2008Journal of Inorganic Biochemistry18 citations Open access
Semantic Scholar
NMR Structure Determination of Ion Pairs Derived from Quinine: A Model for Templating in Asymmetric Phase-Transfer Reductions by BH(4)(-) with Implications for Rational Design of Phase-Transfer Catalysts.
Christine Hofstetter, P. Wilkinson, T. Pochapsky
1999Journal of Organic Chemistry18 citations
Semantic Scholar
Nickel in Acireductone Dioxygenase
T. Pochapsky, Ting-Ting Ju, Marina Dang, Rachel Beaulieu +2 more
200717 citations
Semantic Scholar
A dynamic understanding of cytochrome P450 structure and function through solution NMR
T. Pochapsky, S. Pochapsky
2020Current Opinion in Biotechnology14 citations Open access
Semantic Scholar
Spring-loading the active site of cytochrome P450cam
Marina Dang, S. Pochapsky, T. Pochapsky
2010Metallomics13 citations Open access
Semantic Scholar
Dual chemistry catalyzed by human acireductone dioxygenase
A. Deshpande, T. Pochapsky, G. Petsko, D. Ringe
2017Protein engineering, design & selection : PEDS12 citations Open access
Semantic Scholar
Some surprising implications of NMR-directed simulations of substrate recognition and binding by cytochrome P450cam (CYP101A1)
Eliana K. Asciutto, T. Pochapsky
2018Journal of Molecular Biology11 citations Open access
Semantic Scholar
Substrate recognition by two different P450s: Evidence for conserved roles in a common fold
D. Tietz, Allison M. Colthart, Susan Sondej Pochapsky, T. Pochapsky
2017Scientific Reports11 citations Open access
Semantic Scholar

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