A. Gozman

Most-cited papers

1. Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

   Eloisi Caldas-Lopes, L. Cerchietti, J. H. Ahn, Cristina C. Clement +14 more

   2009Proceedings of the National Academy of Sciences of the United States of America317 citations Open access

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2. Targeting Hsp90: small-molecule inhibitors and their clinical development

   Tony Taldone, A. Gozman, R. Maharaj, G. Chiosis

   2008Current opinion in pharmacology (Print)289 citations Open access

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3. HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.

   Sachie Marubayashi, Priya Koppikar, Tony Taldone, O. Abdel-Wahab +14 more

   2010Journal of Clinical Investigation191 citations Open access

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4. Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

   Anna Rodina, Pallav D. Patel, Yanlong Kang, Yogita Patel +14 more

   2013Chemistry and Biology103 citations Open access

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5. A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species

   Hong-Liang Zong, A. Gozman, Eloisi Caldas-Lopes, Tony Taldone +15 more

   2015Cell Reports62 citations Open access

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6. Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

   Yanlong Kang, Tony Taldone, Hardik J. Patel, Pallav D. Patel +8 more

   2014Journal of Medicinal Chemistry58 citations Open access

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7. Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

   Tony Taldone, Yanlong Kang, Hardik J. Patel, Maulik R. Patel +9 more

   2014Journal of Medicinal Chemistry51 citations Open access

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8. Synthesis of Reblastatin, Autolytimycin, Non-Benzoquinone Analogs: Potent Inhibitors of Heat Shock Protein 90 (Hsp90)

   I. Wrona, A. Gozman, Tony Taldone, G. Chiosis +1 more

   2010Journal of Organic Chemistry51 citations Open access

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9. Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

   Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D. Patel +17 more

   2014ACS Chemical Biology24 citations Open access

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10. HSP 90 is a therapeutic target in JAK 2-dependent myeloproliferative neoplasms in mice and humans

    Sachie Marubayashi, Priya Koppikar, Tony Taldone, O. Abdel-Wahab +14 more

    201811 citations

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11. Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells

    Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D. Patel +16 more

    20150 citations

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12. Determinants of Apoptotic Sensitivity to HSP90 Inhibition In Acute Myeloid Leukemia

    E. C. Lopes, A. Gozman, Tony Taldone, J. H. Ahn +5 more

    20100 citations

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13. Abstract 5463: YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells

    Anna Rodina, Yanlong Kang, R. Maharaj, A. Gozman +12 more

    20100 citations

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14. Efficacy of the Novel Non-Quinone Based HSP-90 Inhibitor PU-H71 in JAK2V617F and MPLW515L-Induced Murine Models of Myeloproliferative Neoplasms.

    Priya Koppikar, Sachie Marubayashi, Tony Taldone, O. Abdel-Wahab +9 more

    20090 citations

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