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W. Farrugia · SciRah

Researcher profile · Semantic Scholar

W. Farrugia

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W. Farrugia — researcher profile on SciRah

h-index: 20
Works: 56
Citations: 1,135

Most-cited papers

Structural Basis for FcγRIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes
P. Ramsland, W. Farrugia, T. Bradford, C. Sardjono +8 more
2011Journal of Immunology163 citations Open access
Semantic Scholar
Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
P. Ramsland, N. Willoughby, H. Trist, W. Farrugia +3 more
2007Proceedings of the National Academy of Sciences of the United States of America119 citations Open access
Semantic Scholar
Three‐dimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer
E. Yuriev, W. Farrugia, A. Scott, P. Ramsland
2005Immunology and Cell Biology76 citations
Semantic Scholar
Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens.
P. Ramsland, W. Farrugia, T. Bradford, P. Hogarth +1 more
2004Journal of Molecular Biology69 citations
Semantic Scholar
An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 Envelopes
Jasminka Sterjovski, Michael Roche, Melissa J. Churchill, Anne M. Ellett +9 more
2010Virology66 citations Open access
Semantic Scholar
Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.
S. Saini, W. Farrugia, P. Ramsland, A. Kaushik
2003International Immunology58 citations Open access
Semantic Scholar
Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody.
P. Ramsland, S. Terzyan, G. Cloud, C. Bourne +6 more
2006Biochemical Journal48 citations Open access
Semantic Scholar
Crystal structures of human antibodies: a detailed and unfinished tapestry of immunoglobulin gene products
P. Ramsland, W. Farrugia
2002Journal of Molecular Recognition37 citations
Semantic Scholar
Contribution of type II phospholipase A2 to in vitro phospholipase A2 enzymatic activity in human term placenta.
Gregory E. Rice, M. Wong, W. Farrugia, K. Scott
1998Journal of Endocrinology36 citations Open access
Semantic Scholar
The expression of parathyroid hormone-related protein mRNA and immunoreactive protein in human amnion and choriodecidua is increased at term compared with preterm gestation.
N. Curtis, P. Ho, R. King, W. Farrugia +5 more
1997Journal of Endocrinology32 citations
Semantic Scholar
CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity.
Jasminka Sterjovski, Melissa J. Churchill, Michael Roche, Anne M. Ellett +5 more
2011Virology30 citations Open access
Semantic Scholar
Type II phospholipase A2 in human gestational tissues: extractable immuno- and enzymatic activity in fetal membranes.
M. Aitken, W. Farrugia, M. Wong, K. Scott +2 more
1993Biochimica et Biophysica Acta30 citations
Semantic Scholar
Parathyroid hormone-related protein(1-34) in gestational fluids and release from human gestational tissues.
W. Farrugia, P. W. Ho, G. Rice, J. Moseley +2 more
2000Journal of Endocrinology26 citations Open access
Semantic Scholar
Parathyroid hormone(1-34) and parathyroid hormone-related protein(1-34) stimulate calcium release from human syncytiotrophoblast basal membranes via a common receptor.
W. Farrugia, T. de Gooyer, G. Rice, Jane M. Moseley +1 more
2000Journal of Endocrinology25 citations Open access
Semantic Scholar
A Possible Role for Metallic Ions in the Carbohydrate Cluster Recognition Displayed by a Lewis Y Specific Antibody
W. Farrugia, A. Scott, P. Ramsland
2009PLoS ONE24 citations Open access
Semantic Scholar
Metabolism of osteocalcin
W. Farrugia, R. Melick
1986Calcified Tissue International24 citations
Semantic Scholar
Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non‐canonical tumour‐associated mucin 1‐8 peptide
E. Lazoura, Jodie Lodding, W. Farrugia, P. Ramsland +4 more
2006Immunology22 citations Open access
Semantic Scholar
Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications
M. Agostino, M. Sandrin, P. Thompson, W. Farrugia +2 more
2011Expert Opinion on Biological Therapy21 citations
Semantic Scholar
Construction of single-chain Fv with two possible CDR3H conformations but similar inter-molecular forces that neutralize bovine herpesvirus 1.
M. Koti, W. Farrugia, É. Nagy, P. Ramsland +1 more
2010Molecular Immunology20 citations
Semantic Scholar
Structural biology of carbohydrate xenoantigens
E. Yuriev, M. Agostino, W. Farrugia, D. Christiansen +2 more
2009Expert Opinion on Biological Therapy20 citations
Semantic Scholar
Release of Type II phospholipase A2 immunoreactivity and phospholipase A2 enzymatic activity from human placenta.
W. Farrugia, G. Rice, M. Wong, K. Scott +1 more
1997Journal of Endocrinology18 citations
Semantic Scholar
Effects of prednisolone and deflazacort on osteocalcin metabolism in sheep
S. O'Connell, J. Tresham, Carolyn L. Fortune, W. Farrugia +3 more
1993Calcified Tissue International18 citations Open access
Semantic Scholar
A conserved host and pathogen recognition site on immunoglobulins: structural and functional aspects.
B. Wines, H. Trist, W. Farrugia, C. Ngo +5 more
2012Advances in Experimental Medicine and Biology17 citations
Semantic Scholar
PTH/PTHrP receptor and mid-molecule PTHrP regulation of intrauterine PTHrP: PTH/PTHrP receptor antagonism increases SHR fetal weight.
M. Wlodek, R. Di Nicolantonio, K. Westcott, W. Farrugia +2 more
2004Placenta17 citations Open access
Semantic Scholar
Effect of bacterial endotoxin on the in vitro release of Type II phospholipase-A2 and prostaglandin E2 from human placenta.
W. Farrugia, L. Nicholls, Gregory E. Rice
1999Journal of Endocrinology17 citations Open access
Semantic Scholar
Secretory type II PLA2 immunoreactivity and PLA2 enzymatic activity in human gestational tissues before, during and after spontaneous-onset labour at term.
M. Munns, W. Farrugia, R. King, G. Rice
1999Placenta16 citations
Semantic Scholar
Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor
I. Burvenich, W. Farrugia, F. Lee, B. Catimel +10 more
2016mAbs13 citations Open access
Semantic Scholar
Dissimilar aggregation processes govern precipitation and gelation of human IgM cryoglobulins
V. Vallas, W. Farrugia, R. Raison, A. Edmundson +1 more
2007Journal of Molecular Recognition13 citations
Semantic Scholar
The effect of uninephrectomy on osteocalcin metabolism in sheep: a direct evaluation of renal osteocalcin clearance.
W. Farrugia, N. A. Yates, Carolyn L. Fortune, J. Mcdougall +2 more
1991Journal of Endocrinology12 citations
Semantic Scholar
Cold-induced precipitation of a monoclonal IgM: a negative activation enthalpy reaction.
Stefano C. Meliga, W. Farrugia, P. Ramsland, R. Falconer
2013Journal of Physical Chemistry B11 citations Open access
Semantic Scholar
Non-canonical anchor motif peptides bound to MHC class I induce cellular responses.
E. Lazoura, Jodie Lodding, W. Farrugia, Stephanie L. Day +2 more
2009Molecular Immunology7 citations
Semantic Scholar
Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy
M. Agostino, W. Farrugia, M. Sandrin, A. Scott +2 more
20126 citations
Semantic Scholar
The metabolic clearance rate of osteocalcin in sheep
R. Melick, W. Farrugia, C. L. Heaton, K. Quelch +2 more
1988Calcified Tissue International6 citations
Semantic Scholar
Tumor necrosis factor-beta in human pregnancy and labor.
N. Laham, F. V. van Dunné, L. Abraham, W. Farrugia +3 more
1997Journal of Reproductive Immunology5 citations
Semantic Scholar
The roles of the parathyroid glands, parathyroid hormone (PTH), parathyroid hormone-related protein (PTHrP), and elevated plasma calcium in bone formation in fetal lambs
I. Caple, J. A. Heath, Tt Pham, R. MacIsaac +5 more
19905 citations
Semantic Scholar
Reduced intestinal epithelial cell brush border membrane calcium transport in spontaneously hypertensive rats.
T. de Gooyer, W. Farrugia, M. Wlodek
1999Journal of Hypertension4 citations
Semantic Scholar
The effect of monophosphoryl lipid A on lipopolysaccharide-induced prostaglandin E2 release in human choriodecidua.
L. Nicholls, W. Farrugia, Gregory E. Rice
1997Placenta4 citations
Semantic Scholar
Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
I. Burvenich, W. Farrugia, Zhan-Qi Liu, Dahna Makris +6 more
2018Biochemical Journal2 citations
Semantic Scholar
Human IgG1 lacking complement-dependent cytotoxicity: hu3S193 Fc mutant K322A
W. Farrugia, I. Burvenich, A. Scott, P. Ramsland
20180 citations
Semantic Scholar
Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A/H310A
W. Farrugia, I. Burvenich, A. Scott, P. Ramsland
20150 citations
Semantic Scholar
Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type)
W. Farrugia, I. Burvenich, A. Scott, P. Ramsland
20150 citations
Semantic Scholar
Divalent zinc ion mediated aggregation of the hu3S193 Fab.
W. Farrugia, A. Scott, P. Ramsland
20130 citations Open access
Semantic Scholar
Signaling Complexes Human IgG and Formation of Inflammatory RIIa Recognition of g Structural Basis for Fc
D. Wines, A. Scott, P. Hogarth, M. Powell +9 more
20110 citations
Semantic Scholar
Three-dimensional structure of glycosylated fcgammariia (high-responder polymorphism)
P. Ramsland, W. Farrugia, P. Hogarth
20110 citations
Semantic Scholar
Signaling Complexes Human IgG and Formation of Inflammatory RIIa Recognition of g Structural Basis for Fc
D. Wines, A. Scott, P. Hogarth, M. Powell +9 more
20110 citations
Semantic Scholar
1.5 Angstrom resolution structure of glycosylated fcgammariia (low-responder polymorphism)
P. Ramsland, W. Farrugia, P. Hogarth
20110 citations
Semantic Scholar
This information is current as Signaling Complexes Human IgG and Formation of Inflammatory RIIa Recognition of γ Structural Basis for Fc
P. Ramsland, W. Farrugia, T. Bradford, C. Sardjono +8 more
20110 citations
Semantic Scholar
Signaling Complexes Human IgG and Formation of Inflammatory RIIa Recognition of g Structural Basis for Fc
D. Wines, A. Scott, P. Hogarth, M. Powell +9 more
20110 citations
Semantic Scholar
Anti-Lewis Y Fab fragment with Lewis Y antigen in the presence of zinc ions
W. Farrugia, A. Scott, P. Ramsland
20090 citations
Semantic Scholar
Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1
P. Ramsland, N. Willoughby, H. Trist, W. Farrugia +3 more
20070 citations
Semantic Scholar

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