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D. Bracewell · SciRah

Researcher profile · Semantic Scholar

D. Bracewell

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D. Bracewell — researcher profile on SciRah

h-index: 36
Works: 221
Citations: 4,739

Most-cited papers

Manufacturing Exosomes: A Promising Therapeutic Platform.
I. Colao, R. Corteling, D. Bracewell, I. Wall
2018Trends in Molecular Medicine379 citations Open access
Semantic Scholar
The future of host cell protein (HCP) identification during process development and manufacturing linked to a risk‐based management for their control
D. Bracewell, Richard Francis, C. Smales
2015Biotechnology and Bioengineering167 citations Open access
Semantic Scholar
Fabricating electrospun cellulose nanofibre adsorbents for ion-exchange chromatography
Stewart Dods, O. Hardick, Bob Stevens, D. Bracewell
2015Journal of Chromatography A63 citations Open access
Semantic Scholar
Re-use of Protein A Resin: Fouling and Economics
A. Rathore, M. Pathak, G. Ma, D. Bracewell
201561 citations
Semantic Scholar
Strategies to control therapeutic antibody glycosylation during bioprocessing: Synthesis and separation
Elizabeth Edwards, M. Livanos, A. Krueger, A. Dell +3 more
2022Biotechnology and Bioengineering56 citations Open access
Semantic Scholar
Nanofiber adsorbents for high productivity continuous downstream processing.
O. Hardick, Stewart Dods, Bob Stevens, D. Bracewell
2015Journal of Biotechnology51 citations Open access
Semantic Scholar
Enriching leukapheresis improves T cell activation and transduction efficiency during CAR T processing
Elsa Noaks, C. Peticone, E. Kotsopoulou, D. Bracewell
2021Molecular Therapy: Methods & Clinical Development48 citations Open access
Semantic Scholar
Synthesis and Assembly of Hepatitis B Virus-Like Particles in a Pichia pastoris Cell-Free System
Alex J. Spice, Rochelle Aw, D. Bracewell, K. Polizzi
2020Frontiers in Bioengineering and Biotechnology47 citations Open access
Semantic Scholar
Evaluation of fluorescent dyes to measure protein aggregation within mammalian cell culture supernatants
Sheun Oshinbolu, Rachana Shah, G. Finka, Michael J Molloy +2 more
2018Journal of chemical technology and biotechnology47 citations Open access
Semantic Scholar
Cell free protein synthesis: a viable option for stratified medicines manufacturing?
O. Ogonah, K. Polizzi, D. Bracewell
201743 citations Open access
Semantic Scholar
Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture.
Michael Martinez, M. Spitali, E. Norrant, D. Bracewell
2019Trends in Biotechnology39 citations Open access
Semantic Scholar
Investigating heparin affinity chromatography for extracellular vesicle purification and fractionation.
Benjamin Barnes, Thomas Caws, Samantha Thomas, A. Shephard +3 more
2022Journal of Chromatography A36 citations Open access
Semantic Scholar
Mechanical characterisation of agarose-based chromatography resins for biopharmaceutical manufacture.
Mauryn C. Nweke, R. McCartney, D. Bracewell
2017Journal of Chromatography A36 citations Open access
Semantic Scholar
Residual on column host cell protein analysis during lifetime studies of protein A chromatography.
K. Lintern, Mili Pathak, C. Smales, K. Howland +2 more
2016Journal of Chromatography A35 citations Open access
Semantic Scholar
Advanced control strategies for bioprocess chromatography: Challenges and opportunities for intensified processes and next generation products.
Alexander Armstrong, Kieran Horry, Ting-Ting Cui, Martyn Hulley +4 more
2021Journal of Chromatography A34 citations Open access
Semantic Scholar
Lentiviral Vector Purification Using Nanofiber Ion-Exchange Chromatography
J. Ruščić, Christopher M. Perry, T. Mukhopadhyay, Y. Takeuchi +1 more
2019Molecular Therapy: Methods & Clinical Development32 citations Open access
Semantic Scholar
Dual Data-Independent Acquisition Approach Combining Global HCP Profiling and Absolute Quantification of Key Impurities during Bioprocess Development.
Gauthier Husson, Aurélie Delangle, J. O'Hara, S. Cianférani +4 more
2018Analytical Chemistry32 citations Open access
Semantic Scholar
X-ray computed tomography of packed bed chromatography columns for three dimensional imaging and analysis.
T. Johnson, P. Levison, P. Shearing, D. Bracewell
2017Journal of Chromatography A32 citations Open access
Semantic Scholar
Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort
Alex J. Spice, Rochelle Aw, D. Bracewell, K. Polizzi
2020Synthetic and Systems Biotechnology29 citations Open access
Semantic Scholar
Analytics of host cell proteins (HCPs): lessons from biopharmaceutical mAb analysis for Gene therapy products.
D. Bracewell, Victoria B. Smith, M. Delahaye, C. Smales
2021Current Opinion in Biotechnology27 citations Open access
Semantic Scholar
Identification of upstream culture conditions and harvest time parameters that affect host cell protein clearance
Louis J. Wilson, Will Lewis, Richard Kucia-Tran, D. Bracewell
2019Biotechnology progress (Print)27 citations Open access
Semantic Scholar
Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture.
Mauryn C. Nweke, A. Rathore, D. Bracewell
2018Trends in Biotechnology26 citations Open access
Semantic Scholar
Measurement of impurities to support process development and manufacture of biopharmaceuticals
Sheun Oshinbolu, Louis J. Wilson, Will Lewis, Rachana Shah +1 more
201724 citations Open access
Semantic Scholar
Shear effects on aluminum phosphate adjuvant particle properties in vaccine drug products.
O. O. Kolade, Wen-Bin Jin, C. Tengroth, K. D. Green +1 more
2015Journal of Pharmacy and Science24 citations Open access
Semantic Scholar
Neutron reflectivity measurement of protein A–antibody complex at the solid-liquid interface
A. Mazzer, L. Clifton, T. Perevozchikova, P. Butler +2 more
2017Journal of Chromatography A22 citations Open access
Semantic Scholar
Purification of therapeutic & prophylactic mRNA by affinity chromatography
Julian Grinsted, J. Liddell, Emir Bouleghlimat, Ka-Yan Kwok +3 more
2022Cell and Gene Therapy Insights19 citations
Semantic Scholar
Three dimensional characterisation of chromatography bead internal structure using X-ray computed tomography and focused ion beam microscopy.
T. Johnson, Josh J. Bailey, F. Iacoviello, J. Welsh +3 more
2018Journal of Chromatography A19 citations Open access
Semantic Scholar
UV resonance Raman spectroscopy : a process analytical tool for host cell DNA and RNA dynamics in mammalian cell lines
L. Ashton, Catherine E. M. Hogwood, A. Tait, J. Kuligowski +4 more
201519 citations
Semantic Scholar
Time‐dependent sorption behavior of lentiviral vectors during anion‐exchange chromatography
George Pamenter, L. Davies, Carol Knevelman, J. Miskin +3 more
2023Biotechnology and Bioengineering17 citations Open access
Semantic Scholar
Protein A chromatography resin lifetime—impact of feed composition
Mili Pathak, A. Rathore, K. Lintern, D. Bracewell
2018Biotechnology progress (Print)17 citations Open access
Semantic Scholar
Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
Elham Ramin, A. Cardillo, Reinhard Liebers, Johannes Schmölder +11 more
2024Current Opinion in Chemical Engineering16 citations Open access
Semantic Scholar
Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens
Nishant Sawant, K. Kaur, David A. Holland, J. Hickey +13 more
2020Journal of Pharmacy and Science16 citations Open access
Semantic Scholar
Analysis of fouling and breakthrough of process related impurities during depth filtration using confocal microscopy
Maria Parau, T. Johnson, J. Pullen, D. Bracewell
2022Biotechnology progress (Print)15 citations Open access
Semantic Scholar
The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter‐current chromatography
H. El-Sabbahy, David P. Ward, O. Ogonah, L. Deakin +2 more
2018Biotechnology progress (Print)15 citations Open access
Semantic Scholar
Fluorescence based real time monitoring of fouling in process chromatography
Mili Pathak, K. Lintern, V. Chopda, D. Bracewell +1 more
2017Scientific Reports15 citations Open access
Semantic Scholar
Lentiviral vector determinants of anion‐exchange chromatography elution heterogeneity
George Pamenter, Lee Davies, Ciaran Lamont, Danyal H. Rahim +5 more
2024Biotechnology and Bioengineering14 citations Open access
Semantic Scholar
Solid-Solid Interfacial Contact of Tubing Walls Drives Therapeutic Protein Aggregation During Peristaltic Pumping.
Thomas B. Fanthom, Christopher Wilson, David Gruber, D. Bracewell
2023Journal of Pharmacy and Science14 citations Open access
Semantic Scholar
Escherichia coli-Based Cell-Free Protein Synthesis for Iterative Design of Tandem-Core Virus-Like Particles
Noelle Colant, Beatrice J Melinek, S. Frank, W. Rosenberg +1 more
2021Vaccines14 citations Open access
Semantic Scholar
Characterisation of porous anodic alumina membranes for ultrafiltration of protein nanoparticles as a size mimic of virus particles
A. Sharma, D. Bracewell
2019Journal of Membrane Science14 citations Open access
Semantic Scholar
Drying techniques for the visualisation of agarose-based chromatography media by scanning electron microscopy.
Mauryn C. Nweke, M. Turmaine, R. McCartney, D. Bracewell
2017Biotechnology Journal14 citations Open access
Semantic Scholar
An integrated experimental and economic evaluation of cell therapy affinity purification technologies.
B. Weil, M. Jenkins, S. Uddin, D. Bracewell +3 more
2017Regenerative medicine14 citations Open access
Semantic Scholar
Flocculation on a chip: a novel screening approach to determine floc growth rates and select flocculating agents.
Anand N. P. Radhakrishnan, M. Marques, M. Davies, B. O'Sullivan +2 more
2018Lab on a Chip13 citations Open access
Semantic Scholar
A rational approach to improving titer in Escherichia coli‐based cell‐free protein synthesis reactions
Noelle Colant, Beatrice J Melinek, Jaime Teneb, S. Goldrick +3 more
2020Biotechnology progress (Print)12 citations Open access
Semantic Scholar
Novel constructs and 1-step chromatography protocols for the production of Porcine Circovirus 2d (PCV2d) and Circovirus 3 (PCV3) subunit vaccine candidates
Amber R. Peswani, Jaraspim Narkpuk, A. Krueger, D. Bracewell +5 more
2021Food and Bioproducts Processing11 citations Open access
Semantic Scholar
Identification and classification of host cell proteins during biopharmaceutical process development
Louis J. Wilson, Will Lewis, Richard Kucia-Tran, D. Bracewell
2021Biotechnology progress (Print)10 citations Open access
Semantic Scholar
Exploring Bayesian methods in chromatographic development: Increasing the capacity of the mRNA affinity ligand
S. S. Rosa, David Nunes, Julian Grinsted, Duarte M.F. Prazeres +3 more
2025Separation and Purification Technology9 citations Open access
Semantic Scholar
Reactor design for continuous monoclonal antibody precipitation based upon micro‐mixing
Michael Martinez, Gareth J. Mannall, M. Spitali, E. Norrant +1 more
2021Journal of Chemical Technology & Biotechnology9 citations Open access
Semantic Scholar
In situ neutron scattering of antibody adsorption during protein A chromatography
M. Papachristodoulou, J. Doutch, Hoi Sang Beatrice Leung, A. Church +5 more
2020Journal of Chromatography A9 citations Open access
Semantic Scholar
Analytical tools for monitoring changes in physical and chemical properties of chromatography resin upon reuse
Mili Pathak, K. Lintern, T. Johnson, Aswathy M. Nair +3 more
2019Electrophoresis9 citations Open access
Semantic Scholar
Dynamic modelling of aqueous two-phase systems to quantify the impact of bioprocess design, operation and variability
Nehal K. Patel, D. Bracewell, E. Sorensen
20189 citations Open access
Semantic Scholar

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