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N. Wettschureck · SciRah

Researcher profile · Semantic Scholar

N. Wettschureck

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N. Wettschureck — researcher profile on SciRah

h-index: 40
Works: 106
Citations: 8,955

Most-cited papers

Mammalian G proteins and their cell type specific functions.
N. Wettschureck, S. Offermanns
2005Physiological Reviews1,217 citations
Semantic Scholar
G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension
A. Wirth, Z. Benyó, Martina Lukasova, B. Leutgeb +10 more
2008Nature Medicine670 citations
Semantic Scholar
Platelet-derived nucleotides promote tumor-cell transendothelial migration and metastasis via P2Y2 receptor.
D. Schumacher, Boris Strilic, K. Sivaraj, N. Wettschureck +1 more
2013Cancer Cell608 citations Open access
Semantic Scholar
Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.
Sheng-Peng Wang, Ramesh Chennupati, H. Kaur, András Iring +2 more
2016Journal of Clinical Investigation539 citations Open access
Semantic Scholar
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
C. Özcelik, B. Erdmann, B. Pilz, N. Wettschureck +5 more
2002Proceedings of the National Academy of Sciences of the United States of America492 citations Open access
Semantic Scholar
Rho/Rho-kinase mediated signaling in physiology and pathophysiology
N. Wettschureck, S. Offermanns
2002Journal of molecular medicine337 citations
Semantic Scholar
Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation
J. Albarrán-Juárez, András Iring, Sheng-Peng Wang, Sayali Joseph +5 more
2018Journal of Experimental Medicine279 citations Open access
Semantic Scholar
Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.
Hui Chen, J. C. Assmann, A. Krenz, Mahbubur Rahman +6 more
2014Journal of Clinical Investigation275 citations Open access
Semantic Scholar
G13 is an essential mediator of platelet activation in hemostasis and thrombosis
A. Moers, B. Nieswandt, S. Massberg, N. Wettschureck +8 more
2003Nature Medicine270 citations
Semantic Scholar
Passing the Vascular Barrier: Endothelial Signaling Processes Controlling Extravasation.
N. Wettschureck, Boris Strilic, S. Offermanns
2019Physiological Reviews254 citations Open access
Semantic Scholar
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.
András Iring, Young-June Jin, J. Albarrán-Juárez, M. Siragusa +14 more
2019Journal of Clinical Investigation176 citations Open access
Semantic Scholar
P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.
Sheng-Peng Wang, András Iring, Boris Strilic, Julián Albarrán Juárez +9 more
2015Journal of Clinical Investigation155 citations Open access
Semantic Scholar
G(12)/G(13)-mediated signalling in mammalian physiology and disease.
Thomas Worzfeld, N. Wettschureck, S. Offermanns
2008TIPS - Trends in Pharmacological Sciences146 citations
Semantic Scholar
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages
Iñigo Ruiz de Azúa, Giacomo Mancini, R. Srivastava, Alejandro Aparisi Rey +22 more
2017Journal of Clinical Investigation138 citations Open access
Semantic Scholar
Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Sheng-Peng Wang, Shuang Cao, Malika Arhatte, Dahui Li +13 more
2020Nature Communications137 citations Open access
Semantic Scholar
Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development.
J. Kero, Kashan Ahmed, N. Wettschureck, S. Tunaru +4 more
2007Journal of Clinical Investigation130 citations Open access
Semantic Scholar
Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.
N. Wettschureck, EunAh Lee, S. Libutti, S. Offermanns +2 more
2007Molecular Endocrinology121 citations Open access
Semantic Scholar
Anaphylactic shock depends on endothelial Gq/G11
H. Korhonen, B. Fisslthaler, A. Moers, A. Wirth +6 more
2009Journal of Experimental Medicine110 citations Open access
Semantic Scholar
Tamoxifen‐inducible Cre‐mediated recombination in adipocytes
Antonia Sassmann, S. Offermanns, N. Wettschureck
2010Genesis104 citations
Semantic Scholar
Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis
Sheng-Peng Wang, Bianbian Wang, Yue Shi, Tanja Möller +8 more
2021Blood99 citations Open access
Semantic Scholar
Lineage tracing of cells involved in atherosclerosis.
Julián Albarrán-Juárez, H. Kaur, M. Grimm, S. Offermanns +1 more
2016Atherosclerosis88 citations Open access
Semantic Scholar
Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system
H. Kaur, J. Carvalho, M. Looso, P. Singh +8 more
2017Nature Communications86 citations Open access
Semantic Scholar
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.
F. Wanke, S. Moos, A. Croxford, André P. Heinen +23 more
2017Cell Reports84 citations Open access
Semantic Scholar
Forebrain-Specific Inactivation of Gq/G11 Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation
N. Wettschureck, M. van der Stelt, H. Tsubokawa, H. Krestel +5 more
2006Molecular and Cellular Biology78 citations Open access
Semantic Scholar
The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice.
Antonia Sassmann, B. Gier, H. Grone, G. Drews +2 more
2010Journal of Clinical Investigation77 citations Open access
Semantic Scholar
Mouse models to study G-protein-mediated signaling.
N. Wettschureck, A. Moers, S. Offermanns
2004Pharmacology and Therapeutics71 citations
Semantic Scholar
GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo.
J. Healy, A. Nugent, R. Rempel, Andrea B. Moffitt +16 more
2016Blood65 citations Open access
Semantic Scholar
Gα12/Gα13 Deficiency Causes Localized Overmigration of Neurons in the Developing Cerebral and Cerebellar Cortices
A. Moers, Alexander Nürnberg, S. Goebbels, N. Wettschureck +1 more
2007Molecular and Cellular Biology62 citations Open access
Semantic Scholar
G13 controls angiogenesis through regulation of VEGFR-2 expression.
K. Sivaraj, M. Takefuji, Inga Schmidt, R. Adams +2 more
2013Developmental Cell59 citations Open access
Semantic Scholar
Loss of Gq/11 Family G Proteins in the Nervous System Causes Pituitary Somatotroph Hypoplasia and Dwarfism in Mice
N. Wettschureck, A. Moers, Barbara Wallenwein, A. Parlow +2 more
2005Molecular and Cellular Biology59 citations Open access
Semantic Scholar
Unresponsiveness of Platelets Lacking Both Gαq and Gα13
A. Moers, N. Wettschureck, S. Grüner, B. Nieswandt +1 more
2004Journal of Biological Chemistry59 citations Open access
Semantic Scholar
P 2 Y 2 and G q / G 11 control blood pressure by mediating endothelial mechanotransduction
Sheng-Peng Wang, András Iring, Boris Strilic, J. Juárez +9 more
201955 citations
Semantic Scholar
Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling.
A. Wirth, Sheng-Peng Wang, M. Takefuji, Cong Tang +4 more
2016Cardiovascular Research52 citations
Semantic Scholar
Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility.
Susanne Herroeder, P. Reichardt, Antonia Sassmann, B. Zimmermann +10 more
2009Immunity50 citations Open access
Semantic Scholar
Heterotrimeric G Proteins of the Gq/11 Family Are Crucial for the Induction of Maternal Behavior in Mice
N. Wettschureck, A. Moers, T. Hämäläinen, T. Lemberger +2 more
2004Molecular and Cellular Biology48 citations Open access
Semantic Scholar
Characteristic defects in neural crest cell-specific Gαq/Gα11- and Gα12/Gα13-deficient mice
Dagmara A. Dettlaff-Swiercz, N. Wettschureck, A. Moers, K. Huber +1 more
200544 citations Open access
Semantic Scholar
Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues
Shuya Liu, Shun Lu, Rui Xu, A. Atzberger +3 more
2017Frontiers in Physiology41 citations Open access
Semantic Scholar
Lysophospholipids Control Integrin-dependent Adhesion in Splenic B Cells through Gi and G12/G13 Family G-proteins but Not through Gq/G11*
S. Rieken, Susanne Herroeder, Antonia Sassmann, B. Wallenwein +3 more
2006Journal of Biological Chemistry41 citations Open access
Semantic Scholar
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators
Malarvizhi Gurusamy, D. Tischner, Jingchen Shao, Stephan Klatt +9 more
2021Nature Communications39 citations Open access
Semantic Scholar
RhoGEF12 controls cardiac remodeling by integrating G protein– and integrin-dependent signaling cascades
M. Takefuji, Marcus Krüger, K. Sivaraj, K. Kaibuchi +2 more
2013Journal of Experimental Medicine39 citations Open access
Semantic Scholar
G13-Mediated Signaling Pathway Is Required for Pressure Overload–Induced Cardiac Remodeling and Heart Failure
M. Takefuji, A. Wirth, Martina Lukasova, S. Takefuji +5 more
2012Circulation39 citations Open access
Semantic Scholar
Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2
Rui Li, Jingchen Shao, Young-June Jin, H. Kawase +11 more
2023Nature Communications38 citations Open access
Semantic Scholar
G12/G13 Family G Proteins Regulate Marginal Zone B Cell Maturation, Migration, and Polarization1
S. Rieken, Antonia Sassmann, Susanne Herroeder, B. Wallenwein +3 more
2006Journal of Immunology38 citations Open access
Semantic Scholar
Gαq/11 signaling tonically modulates nociceptor function and contributes to activity‐dependent sensitization
A. Tappe-Theodor, Cristina E. Constantin, I. Tegeder, S. G. Lechner +12 more
2012Pain37 citations Open access
Semantic Scholar
Procontractile G protein–mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling
Till F. Althoff, J. Juárez, K. Troidl, Cong Tang +5 more
2012Journal of Experimental Medicine37 citations Open access
Semantic Scholar
Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
Young-June Jin, Ramesh Chennupati, Rui Li, G. Liang +5 more
202136 citations
Semantic Scholar
Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction
Takuma Tsuda, M. Takefuji, N. Wettschureck, K. Kotani +12 more
2017Journal of Experimental Medicine35 citations Open access
Semantic Scholar
Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices.
A. Moers, Alexander Nürnberg, S. Goebbels, N. Wettschureck +1 more
2008Molecular and Cellular Biology35 citations
Semantic Scholar
Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation.
A. Moers, N. Wettschureck, S. Grüner, B. Nieswandt +1 more
2004Journal of Biological Chemistry35 citations
Semantic Scholar
G 13 -Mediated Signaling Pathway Is Required for Pressure Overload–Induced Cardiac Remodeling and Heart Failure
M. Takefuji, A. Wirth, Martina Lukasova, S. Takefuji +5 more
201234 citations
Semantic Scholar

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S. Offermanns×48
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S. Offermanns — researcher profile on SciRah
A. Moers×13
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A. Moers — researcher profile on SciRah
Sheng-Peng Wang×10
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M. Takefuji×7
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Boris Strilic×6

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Till F. Althoff — researcher profile on SciRah