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T. Daemen · SciRah

Researcher profile · Semantic Scholar

T. Daemen

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T. Daemen — researcher profile on SciRah

h-index: 45
Works: 213
Citations: 9,229

Most-cited papers

The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis
M. Gooden, G. D. de Bock, N. Leffers, T. Daemen +1 more
2011British Journal of Cancer1,223 citations Open access
Semantic Scholar
Myeloid derived suppressor cells—An overview of combat strategies to increase immunotherapy efficacy
O. Draghiciu, J. Lübbers, H. Nijman, T. Daemen
2015Oncoimmunology268 citations Open access
Semantic Scholar
CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer
F. Komdeur, Thalina M. Prins, S. van de Wall, A. Plat +6 more
2017Oncoimmunology159 citations Open access
Semantic Scholar
Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response
M. V. van Poelgeest, M. Welters, Renee Vermeij, Linda F. M. Stynenbosch +23 more
2016Clinical Cancer Research155 citations Open access
Semantic Scholar
Immunization with a P53 synthetic long peptide vaccine induces P53‐specific immune responses in ovarian cancer patients, a phase II trial
N. Leffers, A. Lambeck, Marloes J. M. Gooden, B. Hoogeboom +16 more
2009International Journal of Cancer141 citations Open access
Semantic Scholar
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication
O. Draghiciu, H. Nijman, B. Hoogeboom, T. Meijerhof +1 more
2015Oncoimmunology111 citations Open access
Semantic Scholar
Potentiation of a p53‐SLP vaccine by cyclophosphamide in ovarian cancer: A single‐arm phase II study
Renee Vermeij, N. Leffers, B. Hoogeboom, I. Hamming +12 more
2012International Journal of Cancer89 citations Open access
Semantic Scholar
A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer
E. Dijkgraaf, S. Santegoets, A. Reyners, R. Goedemans +10 more
2015OncoTarget75 citations Open access
Semantic Scholar
CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy
F. Komdeur, M. Wouters, Hagma H. Workel, A. Tijans +15 more
2016OncoTarget72 citations Open access
Semantic Scholar
First-in-Human Phase I Clinical Trial of an SFV-Based RNA Replicon Cancer Vaccine against HPV-Induced Cancers
F. Komdeur, Amrita Singh, S. van de Wall, J. Meulenberg +19 more
2020Molecular Therapy71 citations Open access
Semantic Scholar
Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer
M. Wouters, F. Komdeur, H. Workel, H. Klip +14 more
2015Clinical Cancer Research66 citations
Semantic Scholar
Until which age should women be vaccinated against HPV infection? Recommendation based on cost-effectiveness analyses.
T. Westra, M. Rozenbaum, R. Rogoza, H. Nijman +3 more
2011Journal of Infectious Diseases66 citations
Semantic Scholar
Long‐term clinical and immunological effects of p53‐SLP® vaccine in patients with ovarian cancer
N. Leffers, Renee Vermeij, B. Hoogeboom, Ute Schulze +7 more
2012International Journal of Cancer57 citations Open access
Semantic Scholar
Re-polarization of immunosuppressive macrophages to tumor-cytotoxic macrophages by repurposed metabolic drugs
C. Oyarce, Ana Vizcaino-Castro, Shipeng Chen, A. Boerma +1 more
2021Oncoimmunology56 citations Open access
Semantic Scholar
Noninvasive monitoring of cancer therapy induced activated T cells using [18F]FB-IL-2 PET imaging
S. Hartimath, O. Draghiciu, S. van de Wall, V. Manuelli +4 more
2017Oncoimmunology53 citations Open access
Semantic Scholar
Therapeutic immunization and local low‐dose tumor irradiation, a reinforcing combination
O. Draghiciu, M. Walczak, B. Hoogeboom, K. Franken +3 more
2014International Journal of Cancer49 citations Open access
Semantic Scholar
Identification of genes and pathways associated with cytotoxic T lymphocyte infiltration of serous ovarian cancer
N. Leffers, R. Fehrmann, Mjm Gooden, Urj Schulze +7 more
2010British Journal of Cancer49 citations Open access
Semantic Scholar
Immunological and Clinical Effects of Vaccines Targeting p53-Overexpressing Malignancies
Renee Vermeij, N. Leffers, S. H. van der Burg, C. Melief +2 more
2011Journal of Biomedicine and Biotechnology46 citations Open access
Semantic Scholar
Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity
M. Gooden, Valerie R. Wiersma, A. Boerma, N. Leffers +7 more
2014British Journal of Cancer41 citations Open access
Semantic Scholar
Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens
S. van de Wall, K. Ljungberg, Peng P. Ip, A. Boerma +4 more
2018Oncoimmunology39 citations Open access
Semantic Scholar
Antigen-specific active immunotherapy for ovarian cancer.
N. Leffers, T. Daemen, W. Helfrich, H. Boezen +3 more
2010Cochrane Database of Systematic Reviews39 citations Open access
Semantic Scholar
From Tumor Immunosuppression to Eradication: Targeting Homing and Activity of Immune Effector Cells to Tumors
O. Draghiciu, H. Nijman, T. Daemen
2011Clinical and Developmental Immunology37 citations Open access
Semantic Scholar
Resistance Mechanisms Influencing Oncolytic Virotherapy, a Systematic Analysis
D. Bhatt, R. Chammas, T. Daemen
2021Vaccines36 citations Open access
Semantic Scholar
Inclusion of the benefits of enhanced cross-protection against cervical cancer and prevention of genital warts in the cost-effectiveness analysis of human papillomavirus vaccination in the Netherlands
T. Westra, I. Stirbu-Wagner, S. Dorsman, Eric D. Tutuhatunewa +5 more
2013BMC Infectious Diseases36 citations Open access
Semantic Scholar
Therapeutic vaccination against chronic hepatitis C virus infection.
Peng P. Ip, H. Nijman, J. Wilschut, T. Daemen
2012Antiviral Research36 citations
Semantic Scholar
On discounting of health gains from human papillomavirus vaccination: effects of different approaches.
T. Westra, M. Parouty, W. Brouwer, P. Beutels +6 more
2012Value in Health36 citations Open access
Semantic Scholar
Tumor-infiltrating Cytotoxic T Lymphocytes as Independent Prognostic Factor in Epithelial Ovarian Cancer With Wilms Tumor Protein 1 Overexpression
Renee Vermeij, G. D. de Bock, N. Leffers, K. T. ten Hoor +6 more
2011Journal of immunotherapy35 citations
Semantic Scholar
Interleukin-6 receptor and its ligand interleukin-6 are opposite markers for survival and infiltration with mature myeloid cells in ovarian cancer
M. Wouters, E. Dijkgraaf, M. Kuijjer, E. Jordanova +7 more
2014Oncoimmunology34 citations Open access
Semantic Scholar
Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses.
Peng P. Ip, A. Boerma, J. Regts, T. Meijerhof +3 more
2014Molecular Therapy33 citations Open access
Semantic Scholar
Cost-effectiveness of prophylactic vaccination against human papillomavirus 16/18 for the prevention of cervical cancer: adaptation of an existing cohort model to the situation in the Netherlands.
R. Rogoza, T. A. Westra, N. Ferko, J. J. Tamminga +4 more
2009Vaccine33 citations
Semantic Scholar
Histone Deacetylase 3-Directed PROTACs Have Anti-inflammatory Potential by Blocking Polarization of M0-like into M1-like Macrophages.
Chunlong Zhao, Shipeng Chen, Deng Chen, Clàudia Río-Bergé +4 more
2023Angewandte Chemie32 citations Open access
Semantic Scholar
Prediction model for regional or distant recurrence in endometrial cancer based on classical pathological and immunological parameters
M. Versluis, De A. M. Jong, A. Plat, T. Bosse +13 more
2015British Journal of Cancer30 citations Open access
Semantic Scholar
A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development
O. Draghiciu, A. Boerma, B. Hoogeboom, H. Nijman +1 more
2015Oncoimmunology30 citations Open access
Semantic Scholar
Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer
Renee Vermeij, T. Daemen, G. D. de Bock, P. de Graeff +6 more
2010Clinical and Developmental Immunology29 citations Open access
Semantic Scholar
Heterologous prime-boost immunizations with a virosomal and an alphavirus replicon vaccine.
M. Walczak, A. de Mare, A. Riezebos-Brilman, J. Regts +8 more
2011Molecular Pharmaceutics28 citations
Semantic Scholar
Equity in human papilloma virus vaccination uptake?: sexual behaviour, knowledge and demographics in a cross-sectional study in (un)vaccinated girls in the Netherlands
M. Mollers, Karin Lubbers, S. K. Spoelstra, W. Weijmar-Schultz +6 more
2014BMC Public Health27 citations Open access
Semantic Scholar
Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer.
N. Leffers, Marloes J. M. Gooden, Anna A. Mokhova, W. Kast +6 more
2009Gynecologic Oncology27 citations
Semantic Scholar
Augmentation of alphavirus vector-induced human papilloma virus-specific immune and anti-tumour responses by co-expression of interleukin-12.
A. Riezebos-Brilman, J. Regts, M. Chen, J. Wilschut +1 more
2009Vaccine26 citations
Semantic Scholar
An alphavirus-based therapeutic cancer vaccine: from design to clinical trial
Amrita Singh, Georgia Koutsoumpli, S. van de Wall, T. Daemen
2018Cancer Immunology and Immunotherapy24 citations Open access
Semantic Scholar
Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes
Peng P. Ip, H. Nijman, T. Daemen
2015Vaccines23 citations Open access
Semantic Scholar
Cost-effectiveness of the prophylactic HPV vaccine: an application to the Netherlands taking non-cervical cancers and cross-protection into account.
J. Luttjeboer, T. Westra, J. Wilschut, H. W. Nijman +2 more
2013Vaccine23 citations
Semantic Scholar
Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress
W. A. Ríos-Ocampo, T. Daemen, M. Buist-Homan, K. Faber +2 more
2019Redox Report22 citations Open access
Semantic Scholar
The cost–effectiveness of HPV vaccination in addition to screening: a Dutch perspective
D. Setiawan, J. Luttjeboer, T. Westra, J. Wilschut +5 more
2015Expert Review of Vaccines22 citations Open access
Semantic Scholar
Vvax001, a Therapeutic Vaccine for Patients with HPV16-positive High-grade Cervical Intraepithelial Neoplasia: a Phase II Trial.
A. Eerkens, M. Esajas, K. Brummel, A. Vledder +15 more
2025Clinical Cancer Research21 citations Open access
Semantic Scholar
The combined signatures of hypoxia and cellular landscape provides a prognostic and therapeutic biomarker in hepatitis B virus‐related hepatocellular carcinoma
Shipeng Chen, Yu-Zhen Gao, Y. Wang, T. Daemen
2022International Journal of Cancer19 citations Open access
Semantic Scholar
Tattoo Delivery of a Semliki Forest Virus-Based Vaccine Encoding Human Papillomavirus E6 and E7
S. van de Wall, M. Walczak, Nienke van Rooij, B. Hoogeboom +3 more
2015Vaccines19 citations Open access
Semantic Scholar
Antigen-specific active immunotherapy for ovarian cancer.
N. Leffers, T. Daemen, W. Helfrich, H. Boezen +3 more
2014Cochrane Database of Systematic Reviews19 citations Open access
Semantic Scholar
Modelling the spatial dynamics of oncolytic virotherapy in the presence of virus-resistant tumour cells
Darshak K. Bhatt, Thijs Janzen, T. Daemen, F. Weissing
2022bioRxiv18 citations Open access
Semantic Scholar
Hepatitis C Virus Proteins Core and NS5A Are Highly Sensitive to Oxidative Stress-Induced Degradation after eIF2α/ATF4 Pathway Activation
W. A. Ríos-Ocampo, M. Navas, M. Buist-Homan, K. Faber +2 more
2020Viruses18 citations Open access
Semantic Scholar
The cellular stress response in hepatitis C virus infection: A balancing act to promote viral persistence and host cell survival.
W. A. Ríos-Ocampo, M. Navas, K. Faber, T. Daemen +1 more
2019Virus Research18 citations Open access
Semantic Scholar

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