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A. Quéméner · SciRah

Researcher profile · Semantic Scholar

A. Quéméner

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A. Quéméner — researcher profile on SciRah

h-index: 16
Works: 44
Citations: 1,060

Most-cited papers

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.
Erwan Mortier, A. Quéméner, P. Vusio, I. Lorenzen +4 more
2006Journal of Biological Chemistry262 citations Open access
Semantic Scholar
High antitumor activity of RLI, an interleukin-15 (IL-15)–IL-15 receptor α fusion protein, in metastatic melanoma and colorectal cancer
A. Bessard, V. Solé, G. Bouchaud, A. Quéméner +1 more
2009Molecular Cancer Therapeutics133 citations Open access
Semantic Scholar
Tumor targeting of the IL‐15 superagonist RLI by an anti‐GD2 antibody strongly enhances its antitumor potency
Marie Vincent, A. Bessard, Denis Cochonneau, G. Teppaz +6 more
2013International Journal of Cancer75 citations Open access
Semantic Scholar
Identification of an Interleukin-15α Receptor-binding Site on Human Interleukin-15*
J. Bernard, Catherine Harb, Erwan Mortier, A. Quéméner +8 more
2004Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent Agonist of IL-15 Action through IL-15Rβ/γ
Erwan Mortier, A. Quéméner, P. Vusio, I. Lorenzen +4 more
2006Journal of Biological Chemistry63 citations Open access
Semantic Scholar
The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.
G. Bouchaud, L. Garrigue-Antar, V. Solé, A. Quéméner +5 more
2008Journal of Molecular Biology55 citations
Semantic Scholar
Prevalence, biological phenotype and genotype in moderate/mild hemophilia A with discrepancy between one‐stage and chromogenic factor VIII activity
M. Trossaert, P. Boisseau, A. Quéméner, M. Sigaud +6 more
2011Journal of Thrombosis and Haemostasis48 citations Open access
Semantic Scholar
Production of Recombinant Human Trimeric CD137L (4-1BBL)
Catherine Rabu, A. Quéméner, Y. Jacques, K. Echasserieau +2 more
2005Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse
Marie Vincent, G. Teppaz, L. Lajoie, V. Solé +9 more
2014mAbs41 citations Open access
Semantic Scholar
Molecular evolution and antigenic variation of European brown hare syndrome virus (EBHSV).
A. M. Lopes, L. Capucci, D. Gavier-Widén, G. Le Gall-Reculé +8 more
2014Virology26 citations Open access
Semantic Scholar
Cutting Edge: Differential Fine-Tuning of IL-2– and IL-15–Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor
Dihia Meghnem, S. Morisseau, Marie Frutoso, K. Trillet +8 more
2017Journal of Immunology25 citations Open access
Semantic Scholar
Unexpected ultrasonographic prenatal diagnosis of autosomal dominant polycystic kidney disease
H. Journel, C. Guyot, R. M. Barc, P. Belbeoch +2 more
1989Prenatal Diagnosis24 citations
Semantic Scholar
Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI
Marie Vincent, A. Quéméner, Y. Jacques
2013Oncoimmunology22 citations Open access
Semantic Scholar
Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.
A. Quéméner, M. Maillasson, L. Arzel, B. Sicard +6 more
2017Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles
Marie Frutoso, S. Morisseau, Fella Tamzalit, A. Quéméner +4 more
2018Journal of Immunology20 citations Open access
Semantic Scholar
Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation
Léa Dubreuil, B. Maniangou, P. Chevallier, A. Quéméner +10 more
2020Cancers18 citations Open access
Semantic Scholar
Selective Targeting of IL-15Rα Is Sufficient to Reduce Inflammation
Dihia Meghnem, M. Maillasson, I. Barbieux, S. Morisseau +4 more
2022Frontiers in Immunology13 citations Open access
Semantic Scholar
Docking of human interleukin‐15 to its specific receptor α chain: Correlation between molecular modeling and mutagenesis experimental data
A. Quéméner, J. Bernard, Erwan Mortier, A. Plet +2 more
2006Proteins: Structure, Function, and Bioinformatics12 citations
Semantic Scholar
Identification of Hepatic-like EPO as a Cause of Polycythemia.
Laurent Martin, Darko Maric, Salam Idriss, Marine Delamare +53 more
2025New England Journal of Medicine11 citations
Semantic Scholar
Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology
Erwan Mortier, M. Maillasson, A. Quéméner
2023Journal of Interferon and Cytokine Research9 citations
Semantic Scholar
Genetic diversity and evolution of Hare Calicivirus (HaCV), a recently identified lagovirus from Lepus europaeus.
Clément Droillard, E. Lemaitre, Marina Chatel, A. Quéméner +6 more
2020Infection, Genetics and Evolution9 citations Open access
Semantic Scholar
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma
Noémie Joalland, A. Quéméner, S. Deshayes, Romain Humeau +9 more
2025Journal for ImmunoTherapy of Cancer8 citations Open access
Semantic Scholar
Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia
Fatema Dib, A. Quéméner, Sophie Bayart, P. Boisseau +9 more
2022British Journal of Haematology8 citations Open access
Semantic Scholar
Evolution of interleukin-15 for higher E. coli expression and solubility.
G. Béhar, V. Solé, A. Defontaine, M. Maillasson +3 more
2011Protein engineering, design & selection : PEDS8 citations Open access
Semantic Scholar
A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
F. Dilasser, L. Rose, A. Quéméner, Y. Ferrandez +23 more
2025Cell Reports Medicine7 citations Open access
Semantic Scholar
IL-15Rα membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling
A. Quéméner, S. Morisseau, Rui P. Sousa, K. Trillet +9 more
2019Journal of Cell Science7 citations
Semantic Scholar
230 The exon 3-encoded domain of IL-15Ralpha contributes to IL-15 high-affinity binding and is crucial for IL-15 antagonistic effect of soluble IL-15Ralpha
G. Bouchaud, L. Garrigue-Antar, V. Solé, A. Quéméner +5 more
20087 citations
Semantic Scholar
Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein.
Jimmy Smadja, A. Quéméner, M. Maillasson, B. Sicard +6 more
2021Bioorganic & Medicinal Chemistry5 citations Open access
Semantic Scholar
Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations
Rui P. Sousa, Adèle D. Laurent, A. Quéméner, Erwan Mortier +1 more
2019Molecules4 citations Open access
Semantic Scholar
High antitumor activity of RLI, an IL15-IL15Ralpha fusion protein, in metastatic melanoma and colorectal cancer
A. Bessard, V. Solé, G. Bouchaud, A. Quéméner +1 more
20094 citations
Semantic Scholar
Development of potent Affitin-based bispecific NK cell engagers for the therapy of MSLN-expressing cancers
Tina Briolay, Tacien Petithomme, Hermelyne Gravoueille, Judith Fresquet +12 more
2025Molecular therapy. Oncology3 citations
Semantic Scholar
Reversible DNA Hypermethylation of the Interleukin-15 (IL-15) Promoter Induces IL-15 Expression, Drives the Pathogenesis of T-Cell Large Granular Lymphocytic Leukemia and Provides a Potential Therapeutic Approach Using 5-Azacitidine
J. Brammer, Amy E Boles, A. Mansour, A. Freud +5 more
2019Blood3 citations Open access
Semantic Scholar
Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations?
Pierre Boisseau, Camille Debord, M. Eveillard, A. Quéméner +9 more
2018Platelets2 citations
Semantic Scholar
Identification of Hepatic-like Erythropoietin with Enhanced Activity As a New Cause of Hereditary and Acquired Erythrocytosis
Laurent Martin, Darko Maric, Salam Idriss, Marine Delamare +53 more
2024Blood1 citations
Semantic Scholar
Third French Congress on Mesothelioma
J. Assié, N. Benzerdjeb, Christophe Blanquart, D. Damotte +53 more
2026Pleura and Peritoneum0 citations Open access
Semantic Scholar
Contribution des marqueurs polymorphes KIR et HLA sur le répertoire des cellules Natural Killer et impact en greffes de cellules souches hématopoïétiques haplo-identiques
Léa Dubreuil, Bercelin Maniangou, P. Chevallier, A. Quéméner +10 more
2021Transfusion Clinique et Biologique0 citations
Semantic Scholar
79696 Reversible DNA Hypermethylation of the Interleukin-15 Promoter Induces IL-15 Expression, Drives the Pathogenesis of T-Cell Large Granular Lymphocytic Leukemia (T-LGLL) and Provides a Therapeutic Approach Using 5-Azacitidine
J. Brammer, A. Mishra, Amy E Boles, A. Mansour +3 more
2021Journal of Clinical and Translational Science0 citations Open access
Semantic Scholar
Abstract B033: A novel IL-2 and IL-15 antagonist shifting the immune balance towards tolerance: Potential therapeutic applications
Meghnem Dihia, S. Morisseau, K. Trillet, Marie Frutoso +4 more
20160 citations
Semantic Scholar
CS14-6. Development of two IL15 immunocytokines targeting either GD2- or CD20- tumoral bearing cells.
Marie Vincent, G. Teppaz, V. Solé, A. Bessard +8 more
20110 citations
Semantic Scholar
15Ralpha sushi domains of selective and effective as enhancers of the action of IL-15 through IL-15rbeta / gamma in the prote? Nas 15Ralpha sushi fusion of hiperagonistas-yl 15.
Y. Jacques, Erwan Mortier, A. Plet, A. Quéméner +1 more
20060 citations
Semantic Scholar
IL-15Ralpha sushi Domäin als selektieve und potente Enhancer von IL-15 Aktion durch IL-15Rbeta/gamma, und Hyperagonist (IL15Ralpha sushi -IL15) Fusionsproteine
Y. Jacques, Ariane Plet, E. Mortier, A. Quéméner +1 more
20050 citations
Semantic Scholar
Binding site of IL-15 to IL-15Ralpha and specific mutants of IL-15 having agonist / antagonist activity.
J. Bernard, Catherine Harb, Y. Jacques, Erwan Mortier +2 more
20050 citations
Semantic Scholar
New derivatives of imidazole antagonists and / or agonists of the H3 receptor of histamine, their preparation and their therapeutic applications
J. Schwartz, J. Arrang, M. Garbarg, A. Quéméner +6 more
19950 citations
Semantic Scholar
Novel histamine h3 receptor antagonist and / or agonist imidazole derivatives, their preparation and their therapeutic applications
J. Schwartz, J. Arrang, M. Garbarg, A. Quéméner +6 more
19950 citations
Semantic Scholar

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Erwan Mortier×24
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Erwan Mortier — researcher profile on SciRah
Y. Jacques×22
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M. Maillasson×15
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A. Plet×8
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A. Plet — researcher profile on SciRah

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V. Solé — researcher profile on SciRah

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P. Vusio — researcher profile on SciRah

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A. Bessard — researcher profile on SciRah

L. Garrigue-Antar×5

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Y. Boublik — researcher profile on SciRah

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G. Bouchaud — researcher profile on SciRah

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