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R. Hickerson · SciRah

Researcher profile · Semantic Scholar

R. Hickerson

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R. Hickerson — researcher profile on SciRah

h-index: 27
Works: 53
Citations: 3,540

Most-cited papers

mRNA helicase activity of the ribosome.
S. Takyar, R. Hickerson, H. Noller
2005Cell506 citations Open access
Semantic Scholar
First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.
S. Leachman, R. Hickerson, M. Schwartz, Emily E. Bullough +10 more
2010Molecular Therapy267 citations Open access
Semantic Scholar
Digital Commons @ Trinity Digital Commons @ Trinity
Erika I. Geihe, Christina B. Cooley, Jeff R. Simon, M. K. Kiesewetter +6 more
258 citations
Semantic Scholar
Keratin 16 regulates innate immunity in response to epidermal barrier breach
J. Lessard, Sylvia Piña-Paz, Jeremy D. Rotty, R. Hickerson +3 more
2013Proceedings of the National Academy of Sciences of the United States of America202 citations Open access
Semantic Scholar
Observation of intersubunit movement of the ribosome in solution using FRET.
D. N. Ermolenko, Zigurts K. Majumdar, R. Hickerson, P. Spiegel +2 more
2007Journal of Molecular Biology200 citations
Semantic Scholar
Following movement of the L1 stalk between three functional states in single ribosomes
P. Cornish, D. N. Ermolenko, D. W. Staple, Ho-Ang Lee +3 more
2009Proceedings of the National Academy of Sciences of the United States of America193 citations Open access
Semantic Scholar
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
D. N. Ermolenko, P. Spiegel, Zigurts K. Majumdar, R. Hickerson +2 more
2007Nature Structural &Molecular Biology145 citations
Semantic Scholar
In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles
T. Lobovkina, G. Jacobson, E. Gonzalezgonzalez, R. Hickerson +4 more
2011ACS Nano144 citations Open access
Semantic Scholar
Stability Study of Unmodified siRNA and Relevance to Clinical Use
R. Hickerson, A. Vlassov, Qian Wang, D. Leake +5 more
2008Oligonucleotides128 citations Open access
Semantic Scholar
Single-nucleotide-specific siRNA targeting in a dominant-negative skin model.
R. Hickerson, F. Smith, R. Reeves, C. Contag +5 more
2008Journal of Investigative Dermatology124 citations Open access
Semantic Scholar
Sequence and Stacking Dependence of 8-Oxoguanine Oxidation: Comparison of One-Electron vs Singlet Oxygen Mechanisms
R. Hickerson, Ferran Prat, J. G. Muller, C. Foote +1 more
1999121 citations
Semantic Scholar
Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.
S. Leachman, R. Hickerson, P. R. Hull, F. Smith +6 more
2008Journal of dermatological science (Amsterdam)120 citations Open access
Semantic Scholar
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells
Erika I. Geihe, Christina B. Cooley, Jeff R. Simon, M. K. Kiesewetter +6 more
2012Proceedings of the National Academy of Sciences of the United States of America112 citations Open access
Semantic Scholar
DNA Damage from Sulfite Autoxidation Catalyzed by a Nickel(II) Peptide
J. G. Muller, R. Hickerson, Ronelito J. Perez, C. Burrows
1997106 citations
Semantic Scholar
Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD).
E. Gonzalezgonzalez, T. Speaker, R. Hickerson, Ryan Spitler +4 more
2010Molecular Therapy84 citations Open access
Semantic Scholar
Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: quantitative spectroscopic methods.
Zigurts K. Majumdar, R. Hickerson, H. Noller, R. Clegg
2005Journal of Molecular Biology78 citations
Semantic Scholar
Development of therapeutic siRNAs for pachyonychia congenita.
F. Smith, R. Hickerson, Jane M. Sayers, R. Reeves +4 more
2008Journal of Investigative Dermatology76 citations Open access
Semantic Scholar
Measurement of internal movements within the 30 S ribosomal subunit using Förster resonance energy transfer.
R. Hickerson, Zigurts K. Majumdar, A. Baucom, R. Clegg +1 more
2005Journal of Molecular Biology73 citations
Semantic Scholar
Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.
R. Hickerson, D. Leake, Lana N. Pho, S. Leachman +1 more
2009Journal of dermatological science (Amsterdam)68 citations
Semantic Scholar
Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model.
R. Hickerson, M. A. Flores, D. Leake, M. F. Lara +3 more
2011Journal of Investigative Dermatology56 citations Open access
Semantic Scholar
siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model
E. Gonzalezgonzalez, H. Ra, R. Hickerson, Qian Wang +9 more
2009Gene Therapy53 citations Open access
Semantic Scholar
Mechanism-Based DNA−Protein Cross-Linking of MutY via Oxidation of 8-Oxoguanosine
R. Hickerson, C. L. Chepanoske, Scott D. Williams, S. David +1 more
199947 citations
Semantic Scholar
Inhibition of CD44 Gene Expression in Human Skin Models, Using Self-Delivery Short Interfering RNA Administered by Dissolvable Microneedle Arrays
M. F. Lara, E. Gonzalezgonzalez, T. Speaker, R. Hickerson +4 more
2012Human Gene Therapy44 citations Open access
Semantic Scholar
In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation
V. Hegde, R. Hickerson, Sitheswaran Nainamalai, P. Campbell +3 more
2014Journal of Controlled Release40 citations Open access
Semantic Scholar
Gene Expression Profiling in Pachyonychia Congenita Skin
Yuhua Cao, R. Hickerson, Brandon L Seegmiller, D. Grapov +12 more
2015Journal of dermatological science (Amsterdam)35 citations Open access
Semantic Scholar
Development of skin-humanized mouse models of pachyonychia congenita.
Marta García, F. Larcher, R. Hickerson, E. Baselga +3 more
2011Journal of Investigative Dermatology35 citations Open access
Semantic Scholar
Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device
R. Hickerson, W. Wey, D. Rimm, T. Speaker +6 more
2013Molecular Therapy: Nucleic Acids28 citations Open access
Semantic Scholar
Development of quantitative molecular clinical end points for siRNA clinical trials.
R. Hickerson, S. Leachman, Lana N. Pho, E. Gonzalezgonzalez +6 more
2011Journal of Investigative Dermatology27 citations Open access
Semantic Scholar
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy
Edwin H. A. Allen, D. Courtney, Sarah D. Atkinson, Johnny E. Moore +15 more
2016Human Molecular Genetics26 citations Open access
Semantic Scholar
Visualization of plasmid delivery to keratinocytes in mouse and human epidermis
E. Gonzalezgonzalez, Yeu-Chun Kim, T. Speaker, R. Hickerson +10 more
2011Scientific Reports25 citations Open access
Semantic Scholar
binding Fluorescently labeled ribosomes as a tool for analyzing antibiotic
Beatriz Llano-Sotelo, R. Hickerson, L. Lancaster, H. Noller +1 more
200924 citations
Semantic Scholar
Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters
E. Gonzalezgonzalez, H. Ra, Ryan Spitler, R. Hickerson +2 more
2010Gene Therapy21 citations
Semantic Scholar
SiRNA‐Mediated Selective Inhibition of Mutant Keratin mRNAs Responsible for the Skin Disorder Pachyonychia Congenita
R. Hickerson, F. Smith, W. H. Irwin McLean, M. Landthaler +2 more
2006Annals of the New York Academy of Sciences21 citations
Semantic Scholar
Nanoparticle formation of organic compounds with retained biological activity.
G. Jacobson, Rajesh R. Shinde, Rebecca L. Mccullough, N. Cheng +8 more
2010Journal of Pharmacy and Science18 citations
Semantic Scholar
Therapeutic Prospects of Exon Skipping for Epidermolysis Bullosa
Franciscus C Vermeer, J. Bremer, R. Sietsma, A. Sandilands +8 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Intravital Fluorescence Imaging of Small Interfering RNA–Mediated Gene Repression in a Dual Reporter Melanoma Xenograft Model
R. Hickerson, E. Gonzalezgonzalez, A. Vlassov, Mu Li +3 more
2012Nucleic Acid Therapeutics6 citations Open access
Semantic Scholar
Non-Invasive Intravital Imaging of siRNA-Mediated Mutant Keratin Gene Repression in Skin
R. Hickerson, T. Speaker, M. F. Lara, E. Gonzalezgonzalez +3 more
2016Molecular Imaging and Biology4 citations
Semantic Scholar
Development of a Corneal Bioluminescence Mouse for Real-Time In Vivo Evaluation of Gene Therapies
D. J. Fu, Edwin H. A. Allen, R. Hickerson, D. L. Leslie Pedrioli +1 more
2020Translational Vision Science & Technology3 citations Open access
Semantic Scholar
Imaging Functional Nucleic Acid Delivery to Skin.
R. Kaspar, R. Hickerson, E. Gonzalezgonzalez, M. A. Flores +4 more
2016Methods in molecular biology2 citations
Semantic Scholar
Studies on the Mechanisms of Translocation and Termination
H. Noller, D. N. Ermolenko, A. Korostelev, M. Laurberg +11 more
20112 citations
Semantic Scholar
Erratum to “Measurements of Internal Distance Changes of the 30 S Ribosome Using FRET with Multiple Donor–Acceptor Pairs: Quantitative Spectroscopic Methods” [J. Mol. Biol. (2005) 351, 1123–1145]
Zigurts K. Majumdar, R. Hickerson, H. Noller, R. Clegg
20052 citations Open access
Semantic Scholar
499 A tension-based skin explant model
M. Conneely, S. Roque, T. G. McWilliams, D. Lunny +4 more
20181 citations Open access
Semantic Scholar
Follow ing movement of the L1 stalk between three functional states in single ribosomes. (Proceedings of the National Academy of Sciences of the United States of America (2009) 24:8 (2571-2576) DOI: 10.1073/pnas.0813180106)
P. Cornish, D. N. Ermolenko, D. W. Staple, Ho-Ang Lee +3 more
20091 citations Open access
Semantic Scholar
Protective Effects of Antioxidant Mix Pre-Treatment Against Visible Light-Induced Damage in Dark Skin Phototype
A. Guiotto, Malak Alghamdi, R. Hickerson, Michael J. Conneely +5 more
2026Antioxidants0 citations Open access
Semantic Scholar
1053 Mechanical tension influences the immunocompetency of ex vivo skin tissue
R. Hickerson, D. Grussu, K. Tsutsumi, P. Campbell +1 more
2023Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
PD06 (P26): Using the Vitiligo Noticeability Scale in clinical trials and clinical practice: construct validity, interpretability, reliability and acceptability
E. Eadie, R. Hickerson, M. Conneely, R. Hammond +14 more
2021British Journal of Dermatology0 citations Open access
Semantic Scholar
PD05: Skin safety and efficacy of filtered far ultraviolet C for SARS‐CoV‐2 inactivation
E. Eadie, R. Hickerson, M. Conneely, R. Hammond +7 more
2021British Journal of Dermatology0 citations Open access
Semantic Scholar
969 Wounding response and wound healing in a novel tension-based skin explant model
D. Grussu, M. Conneely, L. Nicholson, K. Hirata +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
Microneedle array for gene delivery to skin Robust transduction of the fetal nervous system with lentivectors Imaging siRNA delivery
E. Gonzalezgonzalez, T. Speaker, R. Hickerson, Ryan Spitler +4 more
20100 citations
Semantic Scholar
Development of Therapeutic siRNAs for Pachyonychia Congenita. Commentary
E. Rugg, F. Smith, R. Hickerson, Jane M. Sayers +5 more
20080 citations
Semantic Scholar

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C. Contag×16
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E. Gonzalezgonzalez×13
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D. Leake×13
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H. Noller — researcher profile on SciRah

W. H. Irwin McLean×9

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L. Milstone — researcher profile on SciRah

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S. Leachman — researcher profile on SciRah

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M. A. Flores×7

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D. N. Ermolenko×5

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D. N. Ermolenko — researcher profile on SciRah