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G. Lambrinidis · SciRah

Researcher profile · Semantic Scholar

G. Lambrinidis

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G. Lambrinidis — researcher profile on SciRah

h-index: 20
Works: 78
Citations: 1,420

Most-cited papers

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay
Chun-Long Ma, M. Sacco, Zi-Lei Xia, G. Lambrinidis +13 more
2021ACS Central Science156 citations Open access
Semantic Scholar
In vitro, in silico and integrated strategies for the estimation of plasma protein binding. A review.
G. Lambrinidis, T. Vallianatou, A. Tsantili-Kakoulidou
2015Advanced Drug Delivery Reviews125 citations
Semantic Scholar
Structure of eukaryotic purine/H+ symporter UapA suggests a role for homodimerization in transport activity
Y. Alguel, S. Amillis, James Leung, G. Lambrinidis +9 more
2016Nature Communications115 citations Open access
Semantic Scholar
Anti-Melanogenic Properties of Greek Plants. A Novel Depigmenting Agent from Morus alba Wood
E. Chaita, G. Lambrinidis, C. Cheimonidi, A. Agalou +5 more
2017Molecules75 citations Open access
Semantic Scholar
A new class of phytoestrogens; evaluation of the estrogenic activity of deoxybenzoins.
N. Fokialakis, G. Lambrinidis, D. Mitsiou, N. Aligiannis +5 more
2004Chemistry and Biology70 citations Open access
Semantic Scholar
Multi-objective optimization methods in novel drug design
G. Lambrinidis, A. Tsantili-Kakoulidou
2020Expert Opinion on Drug Discovery50 citations
Semantic Scholar
The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides
F. Malliou, I. Andreadou, F. Gonzalez, A. Lazou +7 more
2018Journal of Nutritional Biochemistry44 citations Open access
Semantic Scholar
Identification of the Substrate Recognition and Transport Pathway in a Eukaryotic Member of the Nucleobase-Ascorbate Transporter (NAT) Family
V. Kosti, G. Lambrinidis, V. Myrianthopoulos, G. Diallinas +1 more
2012PLoS ONE43 citations Open access
Semantic Scholar
Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors.
A. Vontzalidou, Grigoris Zoidis, E. Chaita, M. Makropoulou +4 more
2012Bioorganic & Medicinal Chemistry Letters40 citations Open access
Semantic Scholar
In silico prediction of human serum albumin binding for drug leads
T. Vallianatou, G. Lambrinidis, A. Tsantili-Kakoulidou
2013Expert Opinion on Drug Discovery39 citations
Semantic Scholar
Supporting online, non-traditional students through the introduction of effective e-learning tools in a pre-university tertiary enabling programme
G. Lambrinidis
201438 citations
Semantic Scholar
The Eurozone between Austerity and Default [In Greek]
C. Lapavitsas, Annina Kaltenbrunner, G. Lambrinidis, D. Lindo +7 more
201034 citations
Semantic Scholar
Erythroidine Alkaloids: A Novel Class of Phytoestrogens
Sefirin Djiogue, M. Halabalaki, D. Njamen, G. Kretzschmar +6 more
2014Planta Medica33 citations Open access
Semantic Scholar
Challenges with multi-objective QSAR in drug discovery
G. Lambrinidis, A. Tsantili-Kakoulidou
2018Expert Opinion on Drug Discovery27 citations
Semantic Scholar
Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments.
Rami Musharrafieh, Panagiotis Lagarias, Chun-Long Ma, Raymond K. Hau +4 more
2020ACS Pharmacology & Translational Science26 citations Open access
Semantic Scholar
Cryptic purine transporters in Aspergillus nidulans reveal the role of specific residues in the evolution of specificity in the NCS1 family
Georgia Sioupouli, G. Lambrinidis, E. Mikros, S. Amillis +1 more
2017Molecular Microbiology26 citations Open access
Semantic Scholar
Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA
Emilia Krypotou, G. Lambrinidis, T. Evangelidis, E. Mikros +1 more
2014Molecular Microbiology24 citations
Semantic Scholar
The estrogen receptor and polyphenols: molecular simulation studies of their interactions, a review
G. Lambrinidis, M. Halabalaki, E. Katsanou, A. Skaltsounis +2 more
200623 citations
Semantic Scholar
Cytotoxic germacranolides from Inula verbascifolia subsp. methanea.
E. Harvala, N. Aligiannis, A. Skaltsounis, Haris Pratsinis +3 more
2002Journal of Natural Products23 citations
Semantic Scholar
Discovery of Novel Adenosine Receptor Antagonists through a Combined Structure- and Ligand-Based Approach Followed by Molecular Dynamics Investigation of Ligand Binding Mode
Panagiotis Lagarias, E. Vrontaki, G. Lambrinidis, D. Stamatis +5 more
2018Journal of Chemical Information and Modeling22 citations Open access
Semantic Scholar
Synthesis and Biological Evaluation of Resveratrol Methoxy Derivatives
E. Fragopoulou, Katerina Gkotsi, Filio Petsini, K. Gioti +4 more
2023Molecules20 citations Open access
Semantic Scholar
X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance
J. Thomaston, Athina Konstantinidi, Lijun Liu, G. Lambrinidis +5 more
2020Biochemistry20 citations Open access
Semantic Scholar
Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from Bjerkandera adusta Targeting Proteostasis Network Modules
K. Georgousaki, N. Tsafantakis, S. Gumeni, G. Lambrinidis +5 more
2020Molecules18 citations Open access
Semantic Scholar
Steroid sulfatase inhibiting lanostane triterpenes - Structure activity relationship and in silico insights.
U. Grienke, T. Kaserer, B. Kirchweger, G. Lambrinidis +5 more
2019Bioorganic chemistry (Print)17 citations
Semantic Scholar
Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli
Maria Botou, P. Lazou, Konstantinos Papakostas, G. Lambrinidis +3 more
2018Molecular Microbiology17 citations Open access
Semantic Scholar
A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis
Kan Li, Michael J. Rudy, Yanmei Hu, Hao-Zhou Tan +11 more
2025Nature Communications16 citations Open access
Semantic Scholar
Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter.
N. Lougiakis, Efthymios-Spyridon Gavriil, M. Kairis, Georgia Sioupouli +7 more
2016Bioorganic & Medicinal Chemistry16 citations
Semantic Scholar
Differential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles.
Xanthippi Alexi, K. Kasiotis, Nikolaos Fokialakis, G. Lambrinidis +4 more
2009Journal of Steroid Biochemistry and Molecular Biology15 citations
Semantic Scholar
Cytosolic N- and C-Termini of the Aspergillus nidulans FurE Transporter Contain Distinct Elements that Regulate by Long Range Effects Function and Specificity.
G. Papadaki, G. Lambrinidis, Andreas Zamanos, E. Mikros +1 more
2019Journal of Molecular Biology14 citations
Semantic Scholar
Investigation of Tumor Cells and Receptor-Ligand Simulation Models for the Development of PET Imaging Probes Targeting PSMA and GRPR and a Possible Crosstalk between the Two Receptors.
Christos Liolios, Christos Patsis, G. Lambrinidis, Efpraxia Tzortzini +4 more
2022Molecular Pharmaceutics13 citations
Semantic Scholar
Novel Carbonyl Analogs of Tamoxifen: Design, Synthesis, and Biological Evaluation
K. Kasiotis, G. Lambrinidis, N. Fokialakis, E. Tzanetou +2 more
2017Frontiers in Chemistry13 citations Open access
Semantic Scholar
Structure-based lead optimization of enterovirus D68 2A protease inhibitors
Bin Tan, Chang Liu, Kan Li, Prakash Jadhav +8 more
2023Journal of Medicinal Chemistry12 citations
Semantic Scholar
Biological evaluation of isoflavonoids from Genista halacsyi using estrogen-target cells: Activities of glucosides compared to aglycones
N. Fokialakis, Xanthippi Alexi, N. Aligiannis, Athina Boulaka +8 more
2019PLoS ONE12 citations Open access
Semantic Scholar
Specific Residues in a Purine Transporter Are Critical for Dimerization, ER Exit, and Function
Anezia Kourkoulou, Pothos Grevias, G. Lambrinidis, Euan Pyle +5 more
2019Genetics12 citations Open access
Semantic Scholar
Analysis of PPAR‐α/γ Activity by Combining 2‐D QSAR and Molecular Simulation
T. Vallianatou, G. Lambrinidis, C. Giaginis, E. Mikros +1 more
2013Molecular Informatics12 citations
Semantic Scholar
Deoxybenzoins are novel potent selective estrogen receptor modulators.
Z. Papoutsi, E. Kassi, N. Fokialakis, S. Mitakou +3 more
2007Steroids12 citations
Semantic Scholar
Recent Advances in Dual COX/LOX Inhibitor Design (2020–2024): Establishing “The Rule of Four for Inflammation”
F. P. Chatzipieris, Errikos Petsas, G. Lambrinidis, Stamatia Vassiliou +1 more
2026Life11 citations
Semantic Scholar
Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
Hao-Zhou Tan, Qian-Ru Zhang, Kyriakos Georgiou, Siyu Zhang +5 more
2025Nature Communications11 citations Open access
Semantic Scholar
Design of Multifaceted Antioxidants: Shifting towards Anti-Inflammatory and Antihyperlipidemic Activity
Ariadni Tzara, G. Lambrinidis, A. Kourounakis
2021Molecules10 citations Open access
Semantic Scholar
Ochraceopyronide, a Rare α-Pyrone-C-lyxofuranoside from a Soil-Derived Fungus Aspergillus ochraceopetaliformis
Mostafa A. Asmaey, D. Abatis, A. Abdel-Razek, G. Lambrinidis +5 more
2021Molecules10 citations Open access
Semantic Scholar
Estrogenic activity of isoflavonoids from the stem bark of the tropical tree Amphimas pterocarpoides, a source of traditional medicines.
J. Tchoumtchoua, M. Makropoulou, Sylvain Benjamin Ateba, Athina Boulaka +9 more
2016Journal of Steroid Biochemistry and Molecular Biology10 citations
Semantic Scholar
Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer
Christos Liolios, Danai Bouziotis, W. Sihver, Martin Schäfer +7 more
2024ACS Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor
Xiang-Lin Huang, Anna Chorianopoulou, Panagoula Kalkounou, M. Georgiou +10 more
2024Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
Analysis of conserved NCS2 motifs in the Escherichia coli xanthine permease XanQ
Ekaterini Karena, Ekaterini Tatsaki, G. Lambrinidis, E. Mikros +1 more
2015Molecular Microbiology8 citations
Semantic Scholar
Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.
P. Nikolaou, G. Lambrinidis, M. Georgiou, D. Karagiannis +12 more
2023Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
QSAR/QSPR Modeling in the Design of Drug Candidates with Balanced Pharmacodynamic and Pharmacokinetic Properties
G. Lambrinidis, Fotios Tsopelas, C. Giaginis, A. Tsantili-Kakoulidou
20177 citations
Semantic Scholar
Uracil/H+ symport by FurE refines aspects of the rocking-bundle mechanism of APC-type transporters.
Iliana Zantza, Yiannis Pyrris, S. Raniolo, Georgia F. Papadaki +4 more
2023Journal of Molecular Biology6 citations
Semantic Scholar
The growth of juvenile Trochus niloticus fed on algae
G. Lambrinidis, J. Luong-Van Thinh, S. Renaud
19976 citations
Semantic Scholar
Accurate calculation of affinity changes to the close state of influenza A M2 transmembrane domain in response to subtle structural changes of adamantyl amines using free energy perturbation methods in different lipid bilayers.
Kyriakos Georgiou, Athina Konstantinidi, Johanna Hutterer, Kathrin Freudenberger +6 more
2023Biochimica et Biophysica Acta - Biomembranes5 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of new raloxifene analogues of improved antagonist activity and endometrial safety.
G. Lambrinidis, C. Gouédard, S. Stasinopoulou, Angeliki Angelopoulou +7 more
2020Bioorganic chemistry (Print)5 citations Open access
Semantic Scholar

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