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K. Yamazaki · SciRah

Researcher profile · Semantic Scholar

K. Yamazaki

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K. Yamazaki — researcher profile on SciRah

h-index: 17
Works: 44
Citations: 1,953

Most-cited papers

Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor.
S. Yaguchi, Y. Fukui, I. Koshimizu, H. Yoshimi +5 more
2006Journal of the National Cancer Institute412 citations Open access
Semantic Scholar
Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel.
T. Yamori, Akio Matsunaga, S. Sato, K. Yamazaki +12 more
1999Cancer Research268 citations
Semantic Scholar
An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.
Shingo Dan, T. Tsunoda, Osamu Kitahara, Rempei Yanagawa +5 more
2002Cancer Research247 citations
Semantic Scholar
p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.
T. Mashima, T. Oh-hara, S. Sato, M. Mochizuki +10 more
2005Journal of the National Cancer Institute116 citations
Semantic Scholar
High‐throughput screening in colorectal cancer tissue‐originated spheroids
J. Kondo, T. Ekawa, H. Endo, K. Yamazaki +12 more
2018Cancer Science112 citations Open access
Semantic Scholar
Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations.
Shingo Dan, M. Okamura, M. Seki, K. Yamazaki +8 more
2010Cancer Research112 citations
Semantic Scholar
Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.
D. Kong, Shingo Dan, K. Yamazaki, T. Yamori
2010European Journal of Cancer79 citations
Semantic Scholar
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays
N. Nakatsu, Y. Yoshida, K. Yamazaki, Tomoki Nakamura +3 more
2005Molecular Cancer Therapeutics77 citations
Semantic Scholar
AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy
Y. Ohashi, H. Iijima, N. Yamaotsu, K. Yamazaki +6 more
2011Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Array-based structure and gene expression relationship study of antitumor sulfonamides including N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide.
T. Owa, A. Yokoi, K. Yamazaki, K. Yoshimatsu +2 more
2002Journal of Medicinal Chemistry69 citations Open access
Semantic Scholar
Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis
Yuya Kitajima, T. Ishii, T. Kohda, M. Ishizuka +5 more
2019Scientific Reports55 citations Open access
Semantic Scholar
Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells.
Kazuhiro Ishizu, Naohide Sunose, K. Yamazaki, T. Tsuruo +3 more
2007Biological and Pharmaceutical Bulletin53 citations Open access
Semantic Scholar
Evaluation of Action Mechanisms of Toxic Chemicals Using JFCR39, a Panel of Human Cancer Cell Lines
N. Nakatsu, Tomoki Nakamura, K. Yamazaki, S. Sadahiro +3 more
2007Molecular Pharmacology43 citations
Semantic Scholar
In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK3CA
D. Kong, T. Yamori, K. Yamazaki, Shingo Dan
2014Investigational new drugs32 citations
Semantic Scholar
Synthesis of functional proteins by mixing peptide motifs.
Hirohide Saito, Takako Honma, T. Minamisawa, K. Yamazaki +3 more
2004Chemistry and Biology31 citations Open access
Semantic Scholar
Synthesis and pharmacological evaluation of the novel pseudo-symmetrical tamoxifen derivatives as anti-tumor agents.
Isamu Shiina, Y. Sano, Kenya Nakata, Takaaki Kikuchi +6 more
2008Biochemical Pharmacology27 citations
Semantic Scholar
Inhibition of proliferation and induction of differentiation of glioma cells with Datura stramonium agglutinin
T. Sasaki, K. Yamazaki, Takao Yamori, T. Endo
2002British Journal of Cancer26 citations Open access
Semantic Scholar
Discovery of phosphatidylinositol 3-kinase inhibitory compounds from the Screening Committee of Anticancer Drugs (SCADS) library.
D. Kong, K. Yamazaki, T. Yamori
2010Biological and Pharmaceutical Bulletin17 citations Open access
Semantic Scholar
Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines
Shingo Dan, M. Shirakawa, Yumiko Mukai, Y. Yoshida +5 more
2003Cancer Science16 citations Open access
Semantic Scholar
p 53-Defective Tumors With a Functional Apoptosome-Mediated Pathway : A New Therapeutic Target
T. Mashima, T. Oh-hara, S. Sato, M. Mochizuki +10 more
200515 citations
Semantic Scholar
Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines
Nachi Namatame, Naomi Tamaki, Y. Yoshizawa, M. Okamura +8 more
2018OncoTarget14 citations Open access
Semantic Scholar
Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors
I. Momose, Hikaru Abe, Takumi Watanabe, Shun-ichi Ohba +5 more
2014Cancer Science12 citations Open access
Semantic Scholar
Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth.
M. Kawatani, Harumi Aono, Takeshi Shimizu, Shouta Ohkura +9 more
2021ACS Chemical Biology10 citations
Semantic Scholar
Identification of a dihydroorotate dehydrogenase inhibitor that inhibits cancer cell growth by proteomic profiling
M. Kawatani, Harumi Aono, S. Hiranuma, Takeshi Shimizu +9 more
2023Oncology Research9 citations Open access
Semantic Scholar
Metabolically inducing defects in DNA repair sensitizes BRCA-wild-type cancer cells to replication stress.
Kenji Watanabe, Tatsuro Yamamoto, Tomoko Fujita, Shinjiro Hino +9 more
2024Science Signaling7 citations
Semantic Scholar
Suppression of tumor metastasis by a RECK-activating small molecule
Y. Yoshida, Kanako Yuki, Shingo Dan, K. Yamazaki +1 more
2022Scientific Reports7 citations Open access
Semantic Scholar
Identification of candidate genes determining chemosensitivity to anti-cancer drugs of gastric cancer cell lines.
Tomoki Nakamura, N. Nakatsu, Y. Yoshida, K. Yamazaki +4 more
2009Biological and Pharmaceutical Bulletin7 citations Open access
Semantic Scholar
Establishment of a Hepatocyte Cell Line Producing Growth‐promoting Factors for Liver‐colonizing Tumor Cells
T. Yamori, Koji Shimada, H. Kanda, Yumiko Nishizuru +8 more
1996Japanese journal of cancer research : Gann4 citations Open access
Semantic Scholar
88 In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines
Shingo Dan, M. Okamura, M. Seki, K. Yamazaki +5 more
20102 citations
Semantic Scholar
Abstract 3909: Potential antitumor effect of a pan-PI3K inhibitor ZSTK474 on human sarcoma cell lines
Shingo Dan, Naomi Tamaki, Nachi Namatame, Y. Yoshizawa +4 more
2019Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Enzyme activity as an actionable axis for small-molecule precision oncology
Kyohhei Fujita, M. Kamiya, S. Dan, Ryo Tachibana +17 more
2026bioRxiv0 citations
Semantic Scholar
Abstract 384: Identification of a lung adenocarcinoma cell line addicted to ERBB4, an actionable target for cancer therapy
Noritaka Tanaka, K. Yamazaki, Y. Uno, Y. Ohashi +3 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
STUDIES In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK 3 CA
D. Kong, T. Yamori, K. Yamazaki, Shingo Dan
20140 citations
Semantic Scholar
Antitumor effects of tyropeptin‐boronic acid derivatives. Gene expression analyses of RPMI8226 cells treated with tyropeptin‐boronic acid derivatives using Agilent human whole genome microarray
I. Momose, Hikaru Abe, Takumi Watanabe, Shun-ichi Ohba +5 more
20140 citations Open access
Semantic Scholar
Abstract LB-357: Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy
Y. Ohashi, H. Iijima, N. Yamaotsu, K. Yamazaki +6 more
20120 citations
Semantic Scholar
513 Development of a Novel Inhibitor of ADP-Ribosylation Factor 1 (Arf1) That Has Potential for Cancer Therapy
Y. Ohashi, H. Iijima, N. Yamaotsu, K. Yamazaki +5 more
20120 citations
Semantic Scholar
Abstract 4399: In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines
Shingo Dan, M. Okamura, M. Seki, K. Yamazaki +2 more
20110 citations
Semantic Scholar
Abstract 2493: Inhibition of phosphoinositide 3-kinase suppressed growth of cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1arrest of cell cycle but not apoptosis
Shingo Dan, M. Okamura, H. Yoshimi, Yumiko Mukai +7 more
20100 citations
Semantic Scholar
Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI 3 K superfamily and human cancer cell line panel
D. Kong, Shingo Dan, K. Yamazaki, T. Yamori
20100 citations
Semantic Scholar
Abstract C67: JFCR39 COMPARE system can predict molecular targets of phophatidylinositol 3‐kinase inhibitors with high resolution
D. Kong, Shingo Dan, K. Yamazaki, T. Yamori
20090 citations
Semantic Scholar
Abstract #LB-214: Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels
Shingo Dan, Hironobu Sugita, K. Yamazaki, T. Yamori
20090 citations
Semantic Scholar
Abstract C55: Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression
Shingo Dan, Hironobu Sugita, M. Seki, Yumiko Mukai +3 more
20090 citations
Semantic Scholar
Abstract C65: Enhanced antitumor effect by the combination of a PI3K inhibitor ZSTK474 with an mTOR inhibitor rapamycin
H. Yoshimi, Mutumi Okamura, K. Yamazaki, T. Yamori
20090 citations
Semantic Scholar
A novel phosphatidylinositol 3-kinase inhibitor, ZSTK474 exerted antitumor activity against human tumor xenografts by oral administration
S. Yaguchi, Y. Fukui, I. Koshimizu, H. Yoshimi +5 more
20050 citations
Semantic Scholar

Frequent co-authors

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T. Yamori×34
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T. Yamori — researcher profile on SciRah
Shingo Dan×27
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M. Okamura×9
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Yumiko Mukai×6
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Yumiko Mukai — researcher profile on SciRah

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D. Kong — researcher profile on SciRah

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Y. Ohashi — researcher profile on SciRah

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S. Hirono — researcher profile on SciRah

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S. Sato — researcher profile on SciRah

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T. Tsuruo — researcher profile on SciRah

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Y. Ishikawa — researcher profile on SciRah

Yumiko Nishimura×5

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Yumiko Nishimura — researcher profile on SciRah

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S. Yaguchi — researcher profile on SciRah