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S. Fling · SciRah

Researcher profile · Semantic Scholar

S. Fling

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S. Fling — researcher profile on SciRah

h-index: 33
Works: 95
Citations: 10K

Most-cited papers

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
L. Walker, S. Phogat, P. Chan-hui, Denise Wagner +18 more
2009Science1,827 citations Open access
Semantic Scholar
Broad neutralization coverage of HIV by multiple highly potent antibodies
L. Walker, M. Huber, K. Doores, Emilia Falkowska +20 more
2011Nature1,559 citations Open access
Semantic Scholar
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma
P. Nghiem, S. Bhatia, E. Lipson, R. Kudchadkar +27 more
2016New England Journal of Medicine1,129 citations Open access
Semantic Scholar
Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea.
S. Fling, D. Gregerson
1986Analytical Biochemistry885 citations
Semantic Scholar
Gene expression markers of Tumor Infiltrating Leukocytes
P. Danaher, S. Warren, L. Dennis, Leonard D'Amico +6 more
2016Journal of Immunotherapy for Cancer712 citations Open access
Semantic Scholar
Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.
P. Nghiem, S. Bhatia, E. Lipson, W. Sharfman +27 more
2018Journal of Clinical Oncology336 citations Open access
Semantic Scholar
HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells
S. Fling, B. Arp, D. Pious
1994Nature300 citations
Semantic Scholar
A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease 1
M. Fort, Afsaneh Mozaffarian, A. G. Stöver, J. da Silva Correia +9 more
2005Journal of Immunology226 citations
Semantic Scholar
Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer-A Phase 1 Study.
T. Uldrick, P. Goncalves, M. Abdul-Hay, A. Claeys +17 more
2019JAMA Oncology213 citations Open access
Semantic Scholar
Pembrolizumab in Relapsed and Refractory Mycosis Fungoides and Sézary Syndrome: A Multicenter Phase II Study.
M. Khodadoust, A. Rook, P. Porcu, F. Foss +29 more
2020Journal of Clinical Oncology208 citations Open access
Semantic Scholar
Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma
Garry P. Nolan, D. Phillips, M. Matusiak, B. Gutierrez +14 more
2020Nature Communications204 citations Open access
Semantic Scholar
Tuberculosis following PD-1 blockade for cancer immunotherapy
Daniel L. Barber, Shunsuke Sakai, R. Kudchadkar, S. Fling +11 more
2019Science Translational Medicine187 citations Open access
Semantic Scholar
PHASE I TRIAL OF ALT-803, A NOVEL RECOMBINANT INTERLEUKIN-15 COMPLEX, IN PATIENTS WITH ADVANCED SOLID TUMORS
K. Margolin, C. Morishima, V. Velcheti, Jeffrey S. Miller +13 more
2018Clinical Cancer Research158 citations Open access
Semantic Scholar
Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab
Nicolas A. Giraldo, Peter Nguyen, Elizabeth L. Engle, G. Kaunitz +23 more
2018Journal of Immunotherapy for Cancer158 citations Open access
Semantic Scholar
CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis.
S. Fling, R. Sutherland, Lisa N. Steele, Bruce E. Hess +5 more
2001Proceedings of the National Academy of Sciences of the United States of America149 citations Open access
Semantic Scholar
The Murine Cytomegalovirus Immunomodulatory Gene m152 Prevents Recognition of Infected Cells by M45-Specific CTL But Does Not Alter the Immunodominance of the M45-Specific CD8 T Cell Response In Vivo1
Marielle C. Gold, M. Munks, Markus Wagner, U. Koszinowski +2 more
2002Journal of Immunology124 citations Open access
Semantic Scholar
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets
N. Bhardwaj, P. Friedlander, A. Pavlick, M. Ernstoff +30 more
2020Nature Cancer120 citations
Semantic Scholar
An Inclusion Membrane Protein from Chlamydia trachomatis Enters the MHC Class I Pathway and Stimulates a CD8+ T Cell Response 1
M. Starnbach, W. P. Loomis, P. Ovendale, David Regan +3 more
2003Journal of Immunology120 citations Open access
Semantic Scholar
Three-year survival, correlates and salvage therapies in patients receiving first-line pembrolizumab for advanced Merkel cell carcinoma
P. Nghiem, S. Bhatia, E. Lipson, W. Sharfman +25 more
2021Journal for ImmunoTherapy of Cancer118 citations Open access
Semantic Scholar
Classically Restricted Human CD8+ T Lymphocytes Derived from Mycobacterium tuberculosis-Infected Cells: Definition of Antigenic Specificity1
D. Lewinsohn, Li-Qing Zhu, Valerie J. Madison, D. Dillon +4 more
2001Journal of Immunology115 citations Open access
Semantic Scholar
S-antigen-specific rat T cell lines recognize peptide fragments of S-antigen and mediate experimental autoimmune uveoretinitis and pinealitis.
D. Gregerson, W. F. Obritsch, S. Fling, J. Cameron
1986Journal of Immunology107 citations Open access
Semantic Scholar
Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with Mycobacterium tuberculosis1
R. Coler, A. Campos-Neto, P. Ovendale, Fiona H. Day +6 more
2001Journal of Immunology106 citations
Semantic Scholar
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy
T. Uldrick, Scott V. Adams, R. Fromentin, Michael Roche +20 more
2022Science Translational Medicine89 citations Open access
Semantic Scholar
Identification of an HIV-1 Clade A Envelope That Exhibits Broad Antigenicity and Neutralization Sensitivity and Elicits Antibodies Targeting Three Distinct Epitopes
S. Hoffenberg, Rebecca L. R. Powell, A. Carpov, Denise Wagner +18 more
2013Journal of Virology79 citations Open access
Semantic Scholar
Pembrolizumab for Treatment of Relapsed/Refractory Mycosis Fungoides and Sezary Syndrome: Clinical Efficacy in a Citn Multicenter Phase 2 Study
M. Khodadoust, A. Rook, P. Porcu, F. Foss +22 more
201673 citations
Semantic Scholar
Metabolic adaptations of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses
K. Odunsi, F. Qian, A. Lugade, Han Yu +32 more
2022Science Translational Medicine70 citations Open access
Semantic Scholar
PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy
Sylvain Simon, V. Voillet, V. Vignard, Zhongen Wu +20 more
2020Journal for ImmunoTherapy of Cancer65 citations Open access
Semantic Scholar
IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC)
R. Pachynski, C. Morishima, R. Szmulewitz, L. Harshman +19 more
2021Journal for ImmunoTherapy of Cancer63 citations Open access
Semantic Scholar
Identification of T cell recognition sites in S-antigen: dissociation of proliferative and pathogenic sites.
D. Gregerson, S. Fling, Wesley F. Obritsch, C. Merryman +1 more
1989Cellular Immunology59 citations
Semantic Scholar
In vitro unresponsiveness to autologous sequences of the immunopathogenic autoantigen, S-antigen.
S. Fling, L. Donoso, D. Gregerson
1991Journal of Immunology36 citations Open access
Semantic Scholar
New interpretable machine-learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy
Evan Greene, G. Finak, Leonard D'Amico, N. Bhardwaj +8 more
2021Patterns34 citations Open access
Semantic Scholar
Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy
Natalie J. Miller, C. Church, S. Fling, R. Kulikauskas +8 more
2018Journal of Immunotherapy for Cancer34 citations Open access
Semantic Scholar
Human CD8+ T Cells Recognize the 60-kDa Cysteine-Rich Outer Membrane Protein from Chlamydia trachomatis1
A. Gervassi, K. Grabstein, P. Probst, B. Hess +2 more
2004Journal of Immunology33 citations
Semantic Scholar
Conserved T cell receptor V gene usage by uveitogenic T cells.
D. Gregerson, S. Fling, C. Merryman, Xiang-Ming Zhang +2 more
1991Clinical Immunology and Immunopathology33 citations
Semantic Scholar
Pembrolizumab in mycosis fungoides with PD-L1 structural variants.
S. Beygi, S. Fernandez-Pol, G. Duran, E. Wang +8 more
2021Blood Advances31 citations Open access
Semantic Scholar
The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.
Hélène G. Bazin, T. J. Murray, William S. Bowen, Afsaneh Mozaffarian +9 more
2008Bioorganic & Medicinal Chemistry Letters30 citations Open access
Semantic Scholar
Characterization of immunologically active cyanogen bromide peptide fragments of bovine and human retinal S-antigen.
D. Gregerson, S. Fling, R. M. Wohlhueter
1986Experimental Eye Research29 citations
Semantic Scholar
Identification of a uveitogenic cyanogen bromide peptide of bovine retinal S‐antigen and preparation of a uveitogenic, peptide‐specific T cell line
D. Gregerson, Wesley F. Obritsch, S. Fling
1987European Journal of Immunology26 citations
Semantic Scholar
HLA-DMA and DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells
S. Fling, B. Arp, D. Pious
199420 citations
Semantic Scholar
A Phase II Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with Malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant Human Flt3 Ligand.
N. Bhardwaj, A. Pavlick, M. Ernstoff, B. Hanks +11 more
201618 citations
Semantic Scholar
A new perspective of S-antigen from immunochemical analysis.
D. Gregerson, S. Fling, W. F. Obritsch, C. Merryman +1 more
1990Current Eye Research17 citations
Semantic Scholar
Merkel cell polyomavirus-specific and CD39+CLA+ CD8 T cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma
H. Ryu, Timothy Bi, T. Pulliam, Korok Sarkar +11 more
2024Cell Reports Medicine16 citations Open access
Semantic Scholar
Effect of CD4+ T cell count on treatment-emergent adverse events among patients with and without HIV receiving immunotherapy for advanced cancer
T. Odeny, K. Lurain, J. Strauss, S. Fling +9 more
2022Journal for ImmunoTherapy of Cancer15 citations Open access
Semantic Scholar
Cell-based gene therapy experiments in murine experimental autoimmune encephalomyelitis
K. Louie, L. Weiner, Jing Du, Harold H. Kochounian +3 more
2005Gene Therapy14 citations
Semantic Scholar
Multiple, autoreactive TCR V beta genes utilized in response to a small pathogenic peptide of an autoantigen in EAU.
S. Fling, Daniel P. Gold, D. Gregerson
1992Cellular Immunology14 citations
Semantic Scholar
Unresponsiveness to self-peptides of S-antigen in EAU: an overview of recent results.
D. Gregerson, S. Fling, L. Donoso, Daniel P. Gold
1992Current Eye Research13 citations
Semantic Scholar
Assignment of several epitopes to cyanogen bromide peptides of bovine retinal S-antigen by immunoblotting with peptide-specific antibodies.
Volker Knospe, S. Fling, D. Gregerson
1988Current Eye Research13 citations
Semantic Scholar
T antigen–specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma
U. K. Hansen, C. Church, A. M. Carnaz Simões, M. S. Frej +8 more
2024Journal of Clinical Investigation12 citations Open access
Semantic Scholar
Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome
Tianying Su, G. Duran, A. Kwang, N. Ramchurren +3 more
2022medRxiv12 citations Open access
Semantic Scholar
A new data-driven cell population discovery and annotation method for single-cell data, FAUST, reveals correlates of clinical response to cancer immunotherapy
Evan Greene, G. Finak, Leonard D'Amico, N. Bhardwaj +8 more
2019bioRxiv12 citations Open access
Semantic Scholar

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