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I. Briaud · SciRah

Researcher profile · Semantic Scholar

I. Briaud

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I. Briaud — researcher profile on SciRah

h-index: 21
Works: 36
Citations: 2,130

Most-cited papers

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids.
I. Briaud, J. Harmon, C. Kelpe, V. Segu +1 more
2001Diabetes320 citations Open access
Semantic Scholar
Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1)*
C. Wrede, L. M. Dickson, M. K. Lingohr, I. Briaud +1 more
2002Journal of Biological Chemistry271 citations Open access
Semantic Scholar
Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration.
S. Jacqueminet, I. Briaud, C. Rouault, G. Reach +1 more
2000Metabolism: Clinical and Experimental181 citations
Semantic Scholar
Differential Activation Mechanisms of Erk-1/2 and p70S6K by Glucose in Pancreatic β-Cells
I. Briaud, M. K. Lingohr, L. M. Dickson, C. Wrede +1 more
2003162 citations
Semantic Scholar
Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.
I. Briaud, C. Kelpe, L. M. Johnson, P. O. Tran +1 more
2002Diabetes132 citations Open access
Semantic Scholar
Insulin Receptor Substrate-2 Proteasomal Degradation Mediated by a Mammalian Target of Rapamycin (mTOR)-induced Negative Feedback Down-regulates Protein Kinase B-mediated Signaling Pathway in β-Cells*
I. Briaud, L. M. Dickson, M. K. Lingohr, J. McCuaig +2 more
2005Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Glucose-induced Translational Control of Proinsulin Biosynthesis Is Proportional to Preproinsulin mRNA Levels in Islet β-Cells but Not Regulated via a Positive Feedback of Secreted Insulin*
B. Wicksteed, C. Alárcon, I. Briaud, M. K. Lingohr +1 more
2003Journal of Biological Chemistry122 citations Open access
Semantic Scholar
Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.
M. Donelan, G. Morfini, Richard Julyan, S. Sommers +7 more
2002Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
I. Briaud, M. K. Lingohr, L. M. Dickson, C. Wrede +1 more
2003Diabetes84 citations
Semantic Scholar
Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
I. Briaud, L. M. Dickson, M. K. Lingohr, J. McCuaig +2 more
2005Journal of Biological Chemistry80 citations
Semantic Scholar
Specific Regulation of IRS-2 Expression by Glucose in Rat Primary Pancreatic Islet β-Cells*
M. K. Lingohr, I. Briaud, L. M. Dickson, J. McCuaig +3 more
2006Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Inhibition of Insulin Secretion by Leptin in Normal Rodent Islets of Langerhans.
V. Poitout, C. Rouault, M. Guerre-Millo, I. Briaud +1 more
1998Endocrinology75 citations Open access
Semantic Scholar
Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-Cells
D. Demozay, Shinichi Tsunekawa, I. Briaud, Ramila Shah +1 more
2011Diabetes61 citations Open access
Semantic Scholar
Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans.
V. Poitout, C. Rouault, M. Guerre-Millo, I. Briaud +1 more
1998Endocrinology59 citations Open access
Semantic Scholar
Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).
Christian E. Wrede, L. M. Dickson, M. K. Lingohr, I. Briaud +1 more
2003Journal of Molecular Endocrinology52 citations Open access
Semantic Scholar
FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes
Shinichi Tsunekawa, D. Demozay, I. Briaud, J. McCuaig +3 more
2011Diabetes46 citations Open access
Semantic Scholar
Long-term exposure of isolated rat islets of Langerhans to supraphysiologic glucose concentrations decreases insulin mRNA levels.
I. Briaud, C. Rouault, Gérard Reach, V. Poitout
1999Metabolism: Clinical and Experimental38 citations
Semantic Scholar
Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells
M. Donelan, G. Morfini, Richard Julyan, S. Sommers +7 more
2002Journal of Biological Chemistry27 citations Open access
Semantic Scholar
40th EASD Annual Meeting of the European Association for the Study of Diabetes
M. Veitenhansl, K. Stegner, F. Hierl, C. Dieterle +496 more
2016Diabetologia26 citations Open access
Semantic Scholar
Plasma alpha-glutathione S-transferase assessed as a marker of liver damage in patients with chronic hepatitis C.
Michel Vaubourdolle, O. Chazouillères, I. Briaud, Claire Legendre +3 more
1995Clinical Chemistry26 citations Open access
Semantic Scholar
Gluco-lipotoxicity of the pancreatic beta cell.
V. Poitout, I. Briaud, C. Kelpe, D. Hagman
2004Annales d'Endocrinologie22 citations
Semantic Scholar
TAP, LMP and HLA-DM polymorphism: 12th International Histocompatibility Workshop study
H. Teisserenc, L. Besnault, I. Briaud, M. Busson +9 more
199712 citations
Semantic Scholar
Anti-Tumor Activity of Novel Small Molecule Wnt Signaling Inhibitor, CWP232291, In Multiple Myeloma
J. Cha, Ji‐Eun Jung, K. Lee, I. Briaud +10 more
201011 citations
Semantic Scholar
Glucose-induced insulin mRNA accumulation is impaired in islets from neonatal streptozotocin-treated rats.
I. Briaud, C. Rouault, D. Bailbé, B. Portha +2 more
2000Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme9 citations
Semantic Scholar
Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression.
M. K. Lingohr, L. M. Dickson, Christian E. Wrede, I. Briaud +3 more
2003Molecular and Cellular Endocrinology8 citations
Semantic Scholar
[Comparison of the activity of beta-lactams against Pseudomonas aeruginosa according to phenotypes of resistance].
F. Bert, I. Briaud, Catherine Branger, N. Lambert-Zechovsky
1996Pathologie et biologie5 citations
Semantic Scholar
Erratum: Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet β-cells (Journal of Biological Chemistry (2006) 281, (15884-15892))
M. K. Lingohr, I. Briaud, L. M. Dickson, J. McCuaig +3 more
20063 citations
Semantic Scholar
Abstract LB-176: Discovery of CWP232291: A novel and potent small molecule inhibitor of Wnt signaling in hematological malignacies
J. Cha, Ji‐Eun Jung, K. Emami, I. Briaud +8 more
20102 citations
Semantic Scholar
Lipotoxicity of the pancreatic beta-cell is associated with a glucose-dependent, substrate-driven increase in esterification of fatty acids into neutral lipids
I. Briaud, J. Harmon, C. Kelpe, V. Segu +1 more
20002 citations
Semantic Scholar
Therapeutic Potential of Small Molecule Inhibitor of Wnt Signaling in Acute Myelogenous Leukemia
I. Briaud, Fnu Tenzin, Jaeyoung Chun, Se-Woong Oh +8 more
20081 citations
Semantic Scholar
Glucose-induced insulin mRNA accumulation is impaired in islets from neonatal streptozotocin-treated rats.
I. Briaud, C. Rouault, D. Bailbé, B. Portha +2 more
2000Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme1 citations
Semantic Scholar
Iconography : Gluco-lipotoxicity of the pancreatic beta cell
V. Poitout, I. Briaud, C. Kelpe, D. Hagman
20080 citations
Semantic Scholar
Microsoft Word-PKB text-CJR-REV.DOC
C. Wrede, L. M. Dickson, Melissa, Lingohr +2 more
20020 citations
Semantic Scholar
Glucose-Induced Insulin mRNA Accumulation is Impaired in Islets from Neonatal Streptozotocin-Treated Rats
I. Briaud, C. Rouault, D. Bailbé, B. Portha +2 more
20000 citations
Semantic Scholar
Glucose-Induced Insulin mRNA Accumulation is Impaired in Islets from Neonatal Streptozotocin-Treated Rats
I. Briaud, C. Rouault, D. Bailbé, B. Portha +2 more
20000 citations
Semantic Scholar
Effets chroniques du glucose et des acides gras sur la fonction de la cellule β-pancréatique : études in vitro et in vivo
I. Briaud
20000 citations
Semantic Scholar

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