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Floyd Sarsoza · SciRah

Researcher profile · Semantic Scholar

Floyd Sarsoza

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Floyd Sarsoza — researcher profile on SciRah

h-index: 18
Works: 36
Citations: 2,249

Most-cited papers

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
R. Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing +10 more
2007Molecular Neurodegeneration564 citations Open access
Semantic Scholar
Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer*
R. Kayed, Anna Pensalfini, Lawrence Margol, Y. Sokolov +4 more
2009Journal of Biological Chemistry358 citations Open access
Semantic Scholar
Amyloid precursor protein (APP) regulates synaptic structure and function
S. Tyan, A. Shih, J. Walsh, H. Murayama +6 more
2012Molecular and cellular neurosciences189 citations Open access
Semantic Scholar
Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain.
M. Nistor, M. Don, M. Parekh, Floyd Sarsoza +8 more
2007Neurobiology of Aging139 citations Open access
Semantic Scholar
Synaptic proteins, neuropathology and cognitive status in the oldest-old.
E. Head, M. Corrada, K. Kahle-Wrobleski, R. Kim +3 more
2009Neurobiology of Aging134 citations Open access
Semantic Scholar
β-Amyloid deposition and tau phosphorylation in clinically characterized aged cats
E. Head, K. Moffat, Pritam Das, Floyd Sarsoza +4 more
2005118 citations
Semantic Scholar
Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals
K. Lee, Guidenn Sulbarán, Shixin Yang, Young-Mun Ji +10 more
2018Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1–Induced Pluripotent Stem Cell Mutant Carriers
Qing Liu, S. Waltz, G. Woodruff, J. Ouyang +9 more
2014JAMA Neurology94 citations Open access
Semantic Scholar
A Two-Year Study with Fibrillar β-Amyloid (Aβ) Immunization in Aged Canines: Effects on Cognitive Function and Brain Aβ
E. Head, V. Pop, V. Vasilevko, M. Hill +8 more
2008Journal of Neuroscience80 citations Open access
Semantic Scholar
Amyloid β-Peptide and Oligomers in the Brain and CSF of Aged Canines
E. Head, V. Pop, Floyd Sarsoza, R. Kayed +5 more
2010Journal of Alzheimer's Disease78 citations Open access
Semantic Scholar
The myosin converter domain modulates muscle performance
D. Swank, A. Knowles, J. A. Suggs, Floyd Sarsoza +3 more
2002Nature Cell Biology75 citations
Semantic Scholar
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and α-synuclein pathology
Jodie Newman, R. A. Rissman, Floyd Sarsoza, R. Kim +5 more
2005Acta Neuropathologica59 citations
Semantic Scholar
A fibril-specific, conformation-dependent antibody recognizes a subset of Aβ plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain
Floyd Sarsoza, Tommy Saing, R. Kayed, Robert Dahlin +10 more
2009Acta Neuropathologica49 citations Open access
Semantic Scholar
Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function
Brea Midthune, S. Tyan, J. Walsh, Floyd Sarsoza +4 more
2012Molecular and cellular neurosciences35 citations Open access
Semantic Scholar
Myosin storage myopathy mutations yield defective myosin filament assembly in vitro and disrupted myofibrillar structure and function in vivo
Meera C. Viswanathan, Rick Tham, William A. Kronert, Floyd Sarsoza +3 more
2017Human Molecular Genetics25 citations Open access
Semantic Scholar
Reduced neuronal expression of synaptic transmission modulator HNK‐1/neural cell adhesion molecule as a potential consequence of amyloid β‐mediated oxidative stress: a proteomic approach
Stefani N. Thomas, Brian A. Soreghan, M. Nistor, Floyd Sarsoza +2 more
2005Journal of Neurochemistry25 citations
Semantic Scholar
Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression
Jennifer Grundman, B. Spencer, Floyd Sarsoza, R. Rissman
2021bioRxiv22 citations Open access
Semantic Scholar
Immunization with fibrillar Aβ1–42 in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Aβ
E. Head, E. Barrett, M. Murphy, Pritam Das +10 more
200621 citations
Semantic Scholar
Modulation of Amyloid-β and Tau in Alzheimer’s Disease Plasma Neuronal-Derived Extracellular Vesicles by Cerebrolysin® and Donepezil
X. A. Alvarez, Charisse N. Winston, James Barlow, Floyd Sarsoza +7 more
2022Journal of Alzheimer's Disease18 citations Open access
Semantic Scholar
Reductions in ATPase activity, actin sliding velocity, and myofibril stability yield muscle dysfunction in Drosophila models of myosin-based Freeman–Sheldon syndrome
Deepti Rao, William A. Kronert, Yi-Ming Guo, K. Hsu +2 more
2019Molecular Biology of the Cell15 citations Open access
Semantic Scholar
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta.
E. Head, E. Barrett, M. Murphy, Pritam Das +10 more
2006Vaccine9 citations
Semantic Scholar
Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2
Jennifer Ngolab, S. Canchi, S. Rasool, Abderrahman Elmaarouf +10 more
2021Neurobiology of Disease8 citations Open access
Semantic Scholar
Leukocyte Surface Biomarkers Implicate Deficits of Innate Immunity in Sporadic Alzheimer’s Disease
Xin Huang, Yihan Li, C. Fowler, J. Doecke +22 more
2022Alzheimer's & Dementia6 citations Open access
Semantic Scholar
Characterizing blood‐based, microglial derived exosomes (MDEs) as biomarkers for Alzheimer’s disease
Charisse N. Winston, Floyd Sarsoza, B. Spencer, Robert A. Rissman
2021Alzheimer's & Dementia6 citations
Semantic Scholar
Amyloid β -Peptide and Oligomers in the Brain and CSF of Aged Canines
E. Head, V. Pop, Floyd Sarsoza, R. Kayed +6 more
20106 citations
Semantic Scholar
Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism
Yi-Ming Guo, William A. Kronert, K. Hsu, Alice Huang +5 more
2020Skeletal Muscle5 citations Open access
Semantic Scholar
Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer’s Disease Mice
André D. G. Leitão, B. Spencer, Floyd Sarsoza, Jennifer Ngolab +4 more
2023Journal of Alzheimer's Disease3 citations Open access
Semantic Scholar
Myosin Transducer Inter-Strand Communication Is Critical for Normal ATPase Activity and Myofibril Structure
William A. Kronert, K. Hsu, Aditi Madan, Floyd Sarsoza +2 more
2022Biology3 citations Open access
Semantic Scholar
Myosin II Head Interaction in Primitive Species
K. Lee, Shixin Yang, Xiong Liu, E. Korn +6 more
20163 citations Open access
Semantic Scholar
18F-fluoropropyl curcumin binding to β-amyloid plaques in transgenic mouse model of Alzheimer's disease
P. Patel, Floyd Sarsoza, V. Vasilevko, Min-Liang Pan +5 more
20082 citations
Semantic Scholar
Validation Studies of CRF Receptor 1 as a Target for AD
K. Nguyen, M. Ellisman, Jasmine Patanapirom, Floyd Sarsoza +1 more
20180 citations
Semantic Scholar
Expression of Myosin Storage Myopathy Mutations in Drosophila Disrupts Muscle Function, Myofibrillar Structure and Causes Defects in Thick Filament Assembly
Meera C. Viswanathan, Rick Tham, William A. Kronert, William Schmidt +4 more
20170 citations Open access
Semantic Scholar
18F-Fluoropropyl curcumin: Improved radiosynthesis and binding to {beta}-amyloid plaques in a transgenic mouse model of Alzheimer's disease
P. Patel, Floyd Sarsoza, B. Easwawramoorthy, W. Tsu +2 more
20080 citations
Semantic Scholar
Evaluation of 18F-nifrolene binding to transgenic mice model of Alzheimer's disease
Narmisha Patel, Balu Easwaramoorthy, Floyd Sarsoza, Rama Pichika +2 more
20080 citations
Semantic Scholar
P2-008 β-Amyloid accumulation and tau phosphorylation in the aged cat brain: comparison with Alzheimer's disease and Down syndrome
E. Head, K. Moffatt, Pritam Das, Floyd Sarsoza +3 more
20040 citations
Semantic Scholar
P3-212 Caspase-cleaved tau accumulation in Pick's disease, Lewy body disease and frontotemporal dementia
T. Rohn, Jodie Newman, Floyd Sarsoza, R. Kim +2 more
20040 citations
Semantic Scholar

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