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Gary R. Grotendorst · SciRah

Researcher profile · Semantic Scholar

Gary R. Grotendorst

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Gary R. Grotendorst — researcher profile on SciRah

h-index: 50
Works: 117
Citations: 13K

Most-cited papers

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
D. Bradham, A. Igarashi, R. Potter, Gary R. Grotendorst
1991Journal of Cell Biology901 citations Open access
Semantic Scholar
Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor.
K. Frazier, S. Williams, Devashish Kothapalli, H. Klapper +1 more
1996Journal of Investigative Dermatology763 citations Open access
Semantic Scholar
Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair.
A. Igarashi, H. Okochi, D. Bradham, Gary R. Grotendorst
1993Molecular Biology of the Cell737 citations Open access
Semantic Scholar
Connective tissue growth factor: a mediator of TGF-β action on fibroblasts
Gary R. Grotendorst
1997713 citations Open access
Semantic Scholar
Connective tissue growth factor mediates transforming growth factor β‐induced collagen synthesis: down‐regulation by cAMP
M. R. Duncan, K. Frazier, S. Abramson, S. Williams +3 more
1999The FASEB Journal636 citations
Semantic Scholar
A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene.
Gary R. Grotendorst, H. Okochi, N. Hayashi
1996Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research561 citations
Semantic Scholar
Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders.
A. Igarashi, K. Nashiro, K. Kikuchi, S. Sato +4 more
1996Journal of Investigative Dermatology441 citations Open access
Semantic Scholar
Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis.
Y. Martinet, W. Rom, Gary R. Grotendorst, G. Martin +1 more
1987New England Journal of Medicine427 citations
Semantic Scholar
Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity
Y. Martinet, P. Bitterman, J. Mornex, Gary R. Grotendorst +2 more
1986Nature370 citations
Semantic Scholar
Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts.
Gary R. Grotendorst
1997Cytokine & growth factor reviews337 citations
Semantic Scholar
TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression
K. Takehara, E. Leroy, Gary R. Grotendorst
1987321 citations
Semantic Scholar
Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation
Gary R. Grotendorst, Hamed Rahmanie, M. R. Duncan
2004The FASEB Journal313 citations
Semantic Scholar
Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis.
A. Igarashi, K. Nashiro, K. Kikuchi, S. Sato +3 more
1995Journal of Investigative Dermatology290 citations Open access
Semantic Scholar
Production of transforming growth factor beta by human peripheral blood monocytes and neutrophils
Gary R. Grotendorst, Georgeanne Smale, D. Pencev
1989Journal of Cellular Physiology259 citations
Semantic Scholar
Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation
Gary R. Grotendorst, M. R. Duncan
2005The FASEB Journal208 citations
Semantic Scholar
Transforming growth factor beta induces anchorage-independent growth of NRK fibroblasts via a connective tissue growth factor-dependent signaling pathway.
Devashish Kothapalli, K. Frazier, A. Welply, P. Segarini +1 more
1997Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research195 citations
Semantic Scholar
EGF and TGF‐alpha are potent chemoattractants for endothelial cells and EGF‐like peptides are present at sites of tissue regeneration
Gary R. Grotendorst, Y. Soma, K. Takehara, M. Charette
1989Journal of Cellular Physiology162 citations
Semantic Scholar
TGF‐β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF‐related peptides
Y. Soma, Gary R. Grotendorst
1989157 citations
Semantic Scholar
Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?
J. Dammeier, M. Brauchle, W. Falk, Gary R. Grotendorst +1 more
1998International Journal of Biochemistry and Cell Biology154 citations Open access
Semantic Scholar
Connective tissue growth factor mediates transforming growth factor b-induced collagen synthesis : down-regulation by cAMP
M. R. Duncan, K. Frazier, S. Abramson, Shawn Williams +3 more
1999151 citations
Semantic Scholar
Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress.
Q. Garrett, P. Khaw, T. Blalock, G. Schultz +2 more
2004Investigative Ophthalmology and Visual Science141 citations
Semantic Scholar
Expression of connective tissue growth factor mRNA in the fibrous stroma of mammary tumors.
K. Frazier, Gary R. Grotendorst
1997International Journal of Biochemistry and Cell Biology139 citations Open access
Semantic Scholar
Elevated levels of PDGF alpha receptors in keloid fibroblasts contribute to an enhanced response to PDGF.
M. Haisa, H. Okochi, Gary R. Grotendorst
1994Journal of Investigative Dermatology139 citations Open access
Semantic Scholar
Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue
N. Iida, Gary R. Grotendorst
1990Molecular and Cellular Biology137 citations Open access
Semantic Scholar
Retinal pigment epithelial cells produce PDGF-like proteins and secrete them into their media.
P. Campochiaro, R. Sugg, Gary R. Grotendorst, L. Hjelmeland
1989Experimental Eye Research131 citations
Semantic Scholar
Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.
J. Mornex, Y. Martinet, K. Yamauchi, P. Bitterman +4 more
1986Journal of Clinical Investigation127 citations Open access
Semantic Scholar
Inhibition of TGF‐β‐stimulated CTGF gene expression and anchorage‐independent growth by cAMP identifies a CTGF‐dependent restriction point in the cell cycle
Devashish Kothapalli, N. Hayashi, Gary R. Grotendorst
1998The FASEB Journal112 citations
Semantic Scholar
Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring.
J. Daniels, G. Schultz, T. Blalock, Q. Garrett +3 more
2003American Journal of Pathology107 citations Open access
Semantic Scholar
Connective tissue growth factor expression and action in human corneal fibroblast cultures and rat corneas after photorefractive keratectomy.
T. Blalock, M. R. Duncan, J. Varela, M. Goldstein +3 more
2003Investigative Ophthalmology and Visual Science98 citations
Semantic Scholar
Connective Tissue Growth Factor
A. Igarashi, D. Bradham, H. Okochi, Gary R. Grotendorst
1992Journal of dermatology (Print)97 citations Open access
Semantic Scholar
Two peptides related to platelet-derived growth factor are present in human wound fluid.
J. Matsuoka, Gary R. Grotendorst
1989Proceedings of the National Academy of Sciences of the United States of America81 citations Open access
Semantic Scholar
CCN proteins are distinct from, and should not be considered members of, the insulin-like growth factor-binding protein superfamily.
Gary R. Grotendorst, L. Lau, B. Perbal
2000Journal of Clinical Endocrinology and Metabolism79 citations Open access
Semantic Scholar
Transforming growth factor-beta-stimulated connective tissue growth factor expression during corneal myofibroblast differentiation.
P. A. Folger, D. Zekaria, Gary R. Grotendorst, S. Masur
2001Investigative Ophthalmology and Visual Science73 citations
Semantic Scholar
Expression of connective tissue growth factor after glaucoma filtration surgery in a rabbit model.
Douglas W. Esson, Arvind Neelakantan, Sandhya A. Iyer, T. Blalock +4 more
2004Investigative Ophthalmology and Visual Science67 citations Open access
Semantic Scholar
Changes in growth factor levels in human wound fluid.
V. Dvonch, R. J. Murphey, J. Matsuoka, Gary R. Grotendorst
1992Surgery67 citations
Semantic Scholar
CTGF modulates cell cycle progression in cAMP‐arrested NRK fibroblasts
Devashish Kothapalli, Gary R. Grotendorst
2000Journal of Cellular Physiology65 citations
Semantic Scholar
Connective tissue growth factor acts within both endothelial cells and β cells to promote proliferation of developing β cells
Michelle A. Guney, Christine P. Petersen, Andre Boustani, M. R. Duncan +7 more
2011Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Connective tissue growth factor is directly related to liver fibrosis.
N. Hayashi, T. Kakimuma, Y. Soma, Gary R. Grotendorst +3 more
2002Hepato-Gastroenterology64 citations
Semantic Scholar
Chemotaxis of rat brain astrocytes to platelet derived growth factor.
J. Bressler, Gary R. Grotendorst, C. Levitov, L. Hjelmeland
1985Brain Research51 citations
Semantic Scholar
Purification and partial characterization of the phospholipase A2 and co-lytic factor from sea anemone (Aiptasia pallida) nematocyst venom.
Gary R. Grotendorst, D. Hessinger
1999Toxicon50 citations
Semantic Scholar
Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: Possible role of Th17 cells in chronic lung pathology
N. Mishra, Jules Rir-sima-ah, Gary R. Grotendorst, R. Langley +6 more
2012International Immunopharmacology49 citations Open access
Semantic Scholar
Platelet‐derived growth factor AA homodimer is the predominant isoform in human platelets and acute human wound fluid
Y. Soma, V. Dvonch, Gary R. Grotendorst
1992The FASEB Journal49 citations
Semantic Scholar
Spectrophotometric assay for the quantitation of cell migration in the Boyden chamber chemotaxis assay.
Gary R. Grotendorst
1987Methods in Enzymology45 citations
Semantic Scholar
Combinatorial signaling by Twisted Gastrulation and Decapentaplegic.
Elizabeth D. Mason, Shawn Williams, Gary R. Grotendorst, J. Marsh
1997Mechanisms of Development43 citations Open access
Semantic Scholar
Chemoattractants and growth factors
Gary R. Grotendorst
199243 citations
Semantic Scholar
Sulfur Mustard Induces Immune Sensitization in Hairless Guinea Pigs
N. Mishra, Jules Rir-sima-ah, T. March, W. Weber +6 more
2009International Immunopharmacology38 citations Open access
Semantic Scholar
Differential binding, biological and biochemical actions of recombinant PDGF AA, AB, and BB molecules on connective tissue cells
Gary R. Grotendorst, A. Igarashi, R. Larson, Y. Soma +1 more
1991Journal of Cellular Physiology37 citations
Semantic Scholar
Doxorubicin-induced impairment of wound healing in rats.
W. Lawrence, J. Norton, A. K. Harvey, C. Gorschboth +2 more
1986Journal of the National Cancer Institute36 citations
Semantic Scholar
Enzymatic characterization of the major phospholipase A2 component of sea anemone (Aiptasia pallida) nematocyst venom.
Gary R. Grotendorst, D. Hessinger
2000Toxicon35 citations
Semantic Scholar
Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury
J. Benson, J. Seagrave, W. Weber, Colleen D. Santistevan +3 more
2011Wound Repair and Regeneration31 citations Open access
Semantic Scholar

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A. Igarashi×7
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