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L. Ciszak · SciRah

Researcher profile · Semantic Scholar

L. Ciszak

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L. Ciszak — researcher profile on SciRah

h-index: 19
Works: 52
Citations: 898

Most-cited papers

The significance of Treg cells in defective tumor immunity
A. Kosmaczewska, L. Ciszak, S. Potoczek, I. Frydecka
2008Archivum Immunologiae et Therapiae Experimentalis82 citations
Semantic Scholar
Alterations of the expression of T-cell-related costimulatory CD28 and downregulatory CD152 (CTLA-4) molecules in patients with B-cell chronic lymphocytic leukaemia
I. Frydecka, A. Kosmaczewska, D. Boćko, L. Ciszak +3 more
2004British Journal of Cancer62 citations Open access
Semantic Scholar
CTLA-4 overexpression in CD19+/CD5+ cells correlates with the level of cell cycle regulators and disease progression in B-CLL patients
A. Kosmaczewska, L. Ciszak, K. Suwalska, D. Wołowiec +1 more
2005Leukemia49 citations Open access
Semantic Scholar
The CTLA‐4 gene polymorphisms are associated with CTLA‐4 protein expression levels in multiple sclerosis patients and with susceptibility to disease
L. Karabon, A. Kosmaczewska, M. Bilińska, E. Pawlak +7 more
2009Immunology48 citations Open access
Semantic Scholar
Peripheral blood Th17/Treg imbalance in patients with low-active systemic lupus erythematosus.
M. Szmyrka-Kaczmarek, A. Kosmaczewska, L. Ciszak, A. Szteblich +1 more
2014Postępy Higieny i Medycyny Doświadczalnej46 citations Open access
Semantic Scholar
[The role of Th1, Th17, and Treg cells in the pathogenesis of rheumatoid arthritis including anti-inflammatory action of Th1 cytokines].
A. Kosmaczewska, J. Świerkot, L. Ciszak, P. Wiland
2011Postępy Higieny i Medycyny Doświadczalnej39 citations Open access
Semantic Scholar
Lactoferrin-induced up-regulation of zeta (zeta) chain expression in peripheral blood T lymphocytes from cervical cancer patients.
Irena Frydecka, Michał Zimecki, D. Boćko, A. Kosmaczewska +6 more
2002Anticancer Research36 citations
Semantic Scholar
Cell cycle regulatory proteins and apoptosis in B-cell chronic lymphocytic leukemia.
D. Wołowiec, L. Ciszak, A. Kosmaczewska, D. Boćko +3 more
2001Haematologica36 citations
Semantic Scholar
Dysregulated Expression of Both the Costimulatory CD28 and Inhibitory CTLA-4 Molecules in PB T Cells of Advanced Cervical Cancer Patients Suggests Systemic Immunosuppression Related to Disease Progression
A. Kosmaczewska, D. Boćko, L. Ciszak, I. Włodarska-Polińska +4 more
2011Pathology and Oncology Research34 citations Open access
Semantic Scholar
Possible association of cytotoxic T-lymphocyte antigen 4 gene promoter single nucleotide polymorphism with acute rejection of allogeneic kidney transplant.
A. Wiśniewski, M. Kusztal, M. Magott-Procelewska, M. Klinger +8 more
2006Transplantation Proceedings34 citations
Semantic Scholar
Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibody
L. Ciszak, I. Frydecka, D. Wołowiec, A. Szteblich +1 more
2015Tumor Biology33 citations Open access
Semantic Scholar
Alterations in the expression of signal-transducing CD3ζ chain in T cells from patients with chronic inflammatory/autoimmune diseases
L. Ciszak, E. Pawlak, A. Kosmaczewska, S. Potoczek +1 more
2007Archivum Immunologiae et Therapiae Experimentalis33 citations
Semantic Scholar
CD28 costimulatory molecule--expression, structure and function.
D. Boćko, A. Kosmaczewska, L. Ciszak, R. Teodorowska +1 more
2002Archivum Immunologiae et Therapiae Experimentalis33 citations
Semantic Scholar
Expression and functional significance of CTLA-4, a negative regulator of T cell activation.
A. Kosmaczewska, L. Ciszak, D. Boćko, Irena Frydecka
2001Archivum Immunologiae et Therapiae Experimentalis33 citations
Semantic Scholar
Abnormal Expression of BTLA and CTLA-4 Immune Checkpoint Molecules in Chronic Lymphocytic Leukemia Patients
L. Karabon, A. Partyka, L. Ciszak, E. Pawlak-Adamska +7 more
2020Journal of Immunological Research32 citations Open access
Semantic Scholar
Exogenous IL-2 Controls the Balance in Th1, Th17, and Treg Cell Distribution in Patients with Progressive Rheumatoid Arthritis Treated with TNF-Alpha Inhibitors
A. Kosmaczewska, L. Ciszak, J. Świerkot, A. Szteblich +2 more
2014Inflammation24 citations Open access
Semantic Scholar
CD4+CD28null T cells are expanded in moderately active systemic lupus erythematosus and secrete pro-inflammatory interferon gamma, depending on the Disease Activity Index
A. Kosmaczewska, L. Ciszak, Malgorzata Stosio, A. Szteblich +4 more
2020Lupus22 citations
Semantic Scholar
Impaired zeta chain expression and IFN-gamma production in peripheral blood T and NK cells of patients with advanced lung cancer.
L. Ciszak, A. Kosmaczewska, B. Weryńska, A. Szteblich +2 more
2009Oncology Report22 citations Open access
Semantic Scholar
Correlation of blood lymphocyte CTLA‐4 (CD152) induction in Hodgkin's disease with proliferative activity, interleukin 2 and interferon‐gamma production
A. Kosmaczewska, I. Frydecka, D. Boćko, L. Ciszak +1 more
2002British Journal of Haematology22 citations Open access
Semantic Scholar
Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement
A. Kosmaczewska, J. Świerkot, L. Ciszak, A. Szteblich +6 more
2013Rheumatology International19 citations Open access
Semantic Scholar
Deregulated Expression of Immune Checkpoints on Circulating CD4 T Cells May Complicate Clinical Outcome and Response to Treatment with Checkpoint Inhibitors in Multiple Myeloma Patients
Anna Kulikowska de Nałęcz, L. Ciszak, L. Usnarska-Zubkiewicz, I. Frydecka +3 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
High intracellular content of cyclin‐dependent kinase inhibitor p27Kip1 in early‐ and intermediate stage B‐cell chronic lymphocytic leukemia lymphocytes predicts rapid progression of the disease
D. Wołowiec, M. Wójtowicz, L. Ciszak, A. Kosmaczewska +5 more
2009European Journal of Haematology17 citations
Semantic Scholar
CTLA-4 affects expression of key cell cycle regulators of G0/G1 phase in neoplastic lymphocytes from patients with chronic lymphocytic leukaemia
L. Ciszak, I. Frydecka, D. Wołowiec, A. Szteblich +1 more
2015Clinical and Experimental Medicine (Testo stampato)16 citations Open access
Semantic Scholar
CD40L, CD28, and CTLA-4 expression on CD4+ T cells in kidney graft recipients: a relationship with post-transplantation clinical course.
A. Kosmaczewska, M. Magott-Procelewska, I. Frydecka, L. Ciszak +6 more
2006Transplant Immunology16 citations
Semantic Scholar
Inappropriate Expression of PD-1 and CTLA-4 Checkpoints in Myeloma Patients Is More Pronounced at Diagnosis: Implications for Time to Progression and Response to Therapeutic Checkpoint Inhibitors
Anna Kulikowska de Nałęcz, L. Ciszak, L. Usnarska-Zubkiewicz, E. Pawlak +3 more
2023International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
Pretransplant donor and recipient CTLA-4 mRNA and protein levels as a prognostic marker for aGvHD in allogeneic hematopoietic stem cell transplantation.
L. Karabon, M. Markiewicz, A. Kosmaczewska, A. Partyka +7 more
2015Immunology Letters9 citations
Semantic Scholar
Zeta chain expression in T and NK cells in peripheral blood of children with nephrotic syndrome
K. Musiał, L. Ciszak, A. Kosmaczewska, A. Szteblich +2 more
2010Pediatric nephrology (Berlin, West)9 citations
Semantic Scholar
BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production
L. Karabon, Anna Andrzejczak, L. Ciszak, Anna Tomkiewicz +6 more
2021Cells8 citations Open access
Semantic Scholar
Alterations in Both the Activatory and Inhibitory Potential of Peripheral Blood CD4+ T Cells in Rheumatoid Arthritis Patients Correlate with Disease Progression
A. Kosmaczewska, L. Ciszak, J. Świerkot, A. Szteblich +2 more
2013Pathology and Oncology Research8 citations Open access
Semantic Scholar
CD28 downregulation on CD4+ T cells is associated with age of kidney transplant recipient
M. Kusztal, A. Kosmaczewska, M. Magott-Procelewska, I. Frydecka +4 more
2008Transplant International5 citations
Semantic Scholar
Alterations in signal transduction molecule CD3zeta in patients with neoplastic diseases
Irena Frydecka, Pawel Kaczmarek, D. Boćko, A. Kosmaczewska +1 more
19985 citations
Semantic Scholar
Association of Genetic Variants at the CDKN1B and CCND2 Loci Encoding p27Kip1 and Cyclin D2 Cell Cycle Regulators with Susceptibility and Clinical Course of Chronic Lymphocytic Leukemia
L. Ciszak, A. Kosmaczewska, E. Pawlak, Irena Frydecka +2 more
2024International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-γ-Secreting Cells, Especially in Patients with Clinical Complications
A. Kosmaczewska, Joanna Przeździecka-Dołyk, A. Turno-Kręcicka, L. Ciszak +4 more
2020Mediators of Inflammation4 citations Open access
Semantic Scholar
Carp liver DNase--isolation, further characterization and interaction with endogenous actin.
A. Krawczenko, L. Ciszak, M. Malicka-Błaszkiewicz
2005Comparative Biochemistry and Physiology Part B Comparative Biochemistry4 citations
Semantic Scholar
Increased turnover of non-malignant T lymphocytes in patients with chronic lymphocytic leukemia may affect clinical progression.
A. Kosmaczewska, L. Ciszak, Irena Frydecka, E. Pawlak +3 more
2025Polish Archives of Internal Medicine3 citations Open access
Semantic Scholar
Is cyclin D2 a marker of B-cLL cell activation?
A. Kosmaczewska, L. Ciszak, A. Szteblich, A. Laba +3 more
2009Oncology Research3 citations Open access
Semantic Scholar
Impaired ̇ chain expression and IFN-Á production in peripheral blood T and NK cells of patients with advanced lung cancer
L. Ciszak, A. Kosmaczewska, B. Weryńska, A. Szteblich +2 more
20083 citations
Semantic Scholar
[Expression of zeta (zeta) chain in peripheral blood T lymphocytes and NK cells of children with idiopathic nephrotic syndrome (INS)--preliminary results].
K. Musiał, L. Ciszak, A. Kosmaczewska, A. Szteblich +3 more
2006Przeglad lekarski3 citations
Semantic Scholar
Does a natural DNase-actin complex exist in the carp liver cytosol?
A. Krawczenko, L. Ciszak, M. Malicka-Bøaszkiewicz
1994Acta Biochimica Polonica3 citations Open access
Semantic Scholar
Exogenous IL-2 Controls the Balance in Th1, Th17, and Treg Cell Distribution in Patients with Progressive Rheumatoid Arthritis Treated with TNF-Alpha Inhibitors
A. Kosmaczewska, L. Ciszak, J. Świerkot, A. Szteblich +2 more
2014Inflammation2 citations Open access
Semantic Scholar
[Plasma concentration of the shed form of L-selectin (sL-selectin) in patients with acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) and its relation to the clinical course].
K. Kapelko-Słowik, B. Jaźwiec, Słowik Mirosław, D. Wołowiec +5 more
2004Polskie Archiwum Medycyny Wewnetrznej2 citations
Semantic Scholar
miR-155-5p Silencing Does Not Alter BTLA Molecule Expression in CLL T Cells: Implications for Targeted Immunotherapy
A. Kosmaczewska, L. Ciszak, Anna Andrzejczak, Anna Tomkiewicz +8 more
2025Biomolecules1 citations Open access
Semantic Scholar
PD-1 overexpression determines the disproportion of circulating Th1/Th17/Treg cells and clinical outcome of multiple myeloma
A. Kosmaczewska, A. Masternak, K. Kosciow, L. Ciszak +4 more
20191 citations Open access
Semantic Scholar
[CD40L expression on T CD4+ lymphocytes from peripheral blood in patients with relapsing-remitting and secondary progressive multiple sclerosis].
M. Bilińska, I. Frydecka, A. Kosmaczewska, L. Ciszak +2 more
2006Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego1 citations
Semantic Scholar
Immunotherapy with recombinant human interleukin 2 in patients with hematological malignancies after bone marrow or peripheral blood stem cell transplantation.
I. Frydecka, A. Kosmaczewska, D. Boćko, L. Ciszak +1 more
1999Archivum Immunologiae et Therapiae Experimentalis1 citations
Semantic Scholar
Non-Malignant T Cells as Determinants of Immunotherapeutic Response in Chronic Lymphocytic Leukemia: Towards Personalized Strategies
A. Kosmaczewska, L. Ciszak
2026Oncology Research0 citations Open access
Semantic Scholar
Circulating CD16-Positive Monocyte-like Myeloid-Derived Suppressor Cells and Intermediate Monocytes Associated with Clinical and Immunological Complications in Pars Planitis Patients
A. Kosmaczewska, Joanna Przeździecka-Dołyk, L. Ciszak, Zofia Rojek-Gajda +4 more
2025Cells0 citations Open access
Semantic Scholar
PS5:98 Tcr zeta dim lymphocytes in patients with systemic lupus erythematosus
M. Szmyrka, L. Ciszak, A. Szteblich, M. Weglarz +1 more
20180 citations Open access
Semantic Scholar
Dysregulated interferon-γ and interleukin-2 synthesis in peripheral blood T cells in quiescent systemic lupus erythematosus is dependent on the affected T-cell receptor ζ chain expression.
M. Szmyrka, L. Ciszak, M. Weglarz, Karolina Andrzejewska +2 more
2018Polish Archives of Internal Medicine0 citations Open access
Semantic Scholar
ELEVATED CD40L EXPRESSION ACCOMPANIED BY LOW EXPRESSION OF CTLA4 ON PERIPHERAL BLOOD CD4+ CELLS MAY BE ASSOCIATED WITH CHRONIC ALLOGRAFT NEPHROPATHY AND GRAFT LOSS.
M. Magott-Procelewska, A. Kosmaczewska, L. Ciszak, I. Frydecka +3 more
20060 citations Open access
Semantic Scholar

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A. Kosmaczewska×47
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A. Kosmaczewska — researcher profile on SciRah
I. Frydecka×33
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A. Szteblich×21
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D. Boćko — researcher profile on SciRah

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E. Pawlak — researcher profile on SciRah

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S. Potoczek — researcher profile on SciRah

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M. Szmyrka — researcher profile on SciRah