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K. Almholt · SciRah

Researcher profile · Semantic Scholar

K. Almholt

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K. Almholt — researcher profile on SciRah

h-index: 19
Works: 41
Citations: 2,393

Most-cited papers

Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation.
Lotte Bjerre Knudsen, L. Madsen, Søren Andersen, K. Almholt +15 more
2010Endocrinology659 citations Open access
Semantic Scholar
Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation.
M. Johnsen, L. R. Lund, J. Rømer, K. Almholt +1 more
1998Current Opinion in Cell Biology377 citations
Semantic Scholar
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.
O. Vasiljeva, A. Papazoglou, A. Krüger, H. Brodoefel +8 more
2006Cancer Research362 citations Open access
Semantic Scholar
Reduced metastasis of transgenic mammary cancer in urokinase‐deficient mice
K. Almholt, L. R. Lund, J. Rygaard, B. Nielsen +3 more
2005International Journal of Cancer162 citations Open access
Semantic Scholar
Plasminogen activation independent of uPA and tPA maintains wound healing in gene‐deficient mice
L. R. Lund, K. Green, A. Stoop, M. Ploug +8 more
2006EMBO Journal147 citations Open access
Semantic Scholar
Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors.
Birgitte Grum-Schwensen, J. Klingelhöfer, M. Grigorian, K. Almholt +3 more
2010Cancer Research85 citations
Semantic Scholar
Stromal cell involvement in cancer.
K. Almholt, M. Johnsen
2003Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer75 citations
Semantic Scholar
Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice
K. Almholt, B. Nielsen, T. Frandsen, N. Brünner +2 more
2003Oncogene71 citations Open access
Semantic Scholar
Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion
A. Fleetwood, A. Achuthan, H. Schultz, A. Nansen +3 more
2014Journal of Immunology52 citations
Semantic Scholar
Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas.
T. X. Pedersen, C. Pennington, K. Almholt, I. Christensen +5 more
2005Carcinogenesis49 citations Open access
Semantic Scholar
Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model
K. Almholt, A. Juncker-Jensen, O. D. Laerum, K. Danø +3 more
2008Molecular Cancer Therapeutics47 citations Open access
Semantic Scholar
Extracellular Proteolysis in Transgenic Mouse Models of Breast Cancer
K. Almholt, K. Green, A. Juncker-Jensen, B. Nielsen +2 more
2007Journal of mammary gland biology and neoplasia40 citations Open access
Semantic Scholar
Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysis in Vivo*
I. Lund, A. Jögi, Birgitte Rønø, M. Rasch +6 more
2008Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Profibrinolytic effects of metalloproteinases during skin wound healing in the absence of plasminogen.
K. Green, K. Almholt, M. Ploug, Birgitte Rønø +5 more
2008Journal of Investigative Dermatology30 citations Open access
Semantic Scholar
Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells.
S. Thornton, Harini Raghu, C. Cruz, Malinda D. Frederick +5 more
2017Blood Advances29 citations Open access
Semantic Scholar
Indication of a role of plasminogen activator inhibitor type 1 in protecting murine fibrosarcoma cells against apoptosis
M. U. Rømer, A. Due, J. K. Larsen, K. Hofland +6 more
2005Thrombosis and Haemostasis29 citations
Semantic Scholar
Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models
K. Almholt, J. Hebsgaard, A. Nansen, C. Andersson +15 more
2018Journal of Immunology24 citations Open access
Semantic Scholar
Concomitant lack of MMP9 and uPA disturbs physiological tissue remodeling.
I. Lund, B. Nielsen, K. Almholt, Birgitte Rønø +6 more
2011Developmental Biology23 citations Open access
Semantic Scholar
Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera.
K. Almholt, Søren Tullin, O. Skyggebjerg, K. Scudder +2 more
2004Cellular Signalling23 citations
Semantic Scholar
Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor.
Lene Hansen, L. C. Petersen, B. Lauritzen, J. Clausen +5 more
2014Thrombosis Research17 citations
Semantic Scholar
Spontaneous metastasis in matrix metalloproteinase 3‐deficient mice
A. Juncker-Jensen, J. Rømer, C. Pennington, L. R. Lund +1 more
2009Molecular Carcinogenesis14 citations Open access
Semantic Scholar
Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8‐GP) and development of a human pharmacokinetic prediction model
F. Rode, K. Almholt, M. Petersen, M. Kreilgaard +7 more
2018Journal of Thrombosis and Haemostasis10 citations Open access
Semantic Scholar
Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer
T. Thurison, K. Almholt, H. Gårdsvoll, M. Ploug +2 more
2016Molecular Carcinogenesis8 citations
Semantic Scholar
Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation
K. Almholt, A. Juncker-Jensen, Ole Didrik Laerum, M. Johnsen +2 more
2013Clinical and Experimental Metastasis7 citations
Semantic Scholar
Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice.
R. Stagaard, C. D. Ley, K. Almholt, L. H. Olsen +2 more
2018Blood Advances6 citations Open access
Semantic Scholar
Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR
K. Almholt, O. D. Laerum, B. Nielsen, I. Lund +3 more
2015Clinical and Experimental Metastasis4 citations
Semantic Scholar
Sensitive and specific in situ hybridization for early drug discovery.
P. Usher, E. Galsgaard, K. Kruse, Ji-Shu Wang +3 more
2014Methods in molecular biology4 citations
Semantic Scholar
CTLA4‐Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats
Gabi Overgaard Øvlisen, P. Thygesen, K. Weldingh, E. Bloem +5 more
2022Haemophilia2 citations
Semantic Scholar
Normal Neurodevelopment and Fertility in Juvenile Male Rats Exposed to Polyethylene Glycol Following Dosing With PEGylated rFIX (Nonacog Beta Pegol, N9-GP): Evidence from a 10-Week Repeat-Dose Toxicity Study
V. F. H. Jensen, L. H. Schefe, H. Jacobsen, A. Mølck +12 more
2022International journal of toxicology2 citations
Semantic Scholar
The Plasminogen Activation System in Tissue Remodeling and Cancer Invasion
K. Almholt, A. Juncker-Jensen, K. Green, H. Solberg +2 more
20082 citations
Semantic Scholar
Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis
K. Almholt, Ji-Shu Wang, J. Pass, G. Røder +10 more
2020Journal of molecular medicine1 citations
Semantic Scholar
Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR
K. Almholt, O. D. Laerum, B. Nielsen, I. Lund +3 more
2015Clinical and Experimental Metastasis0 citations
Semantic Scholar
Degradation, and Adhesion Three-Dimensional Invasion, Matrix Central Regulator of Macrophage Urokinase Plasminogen Activator Is a
A. Hamilton, A. Nansen, K. Almholt, P. Usher +4 more
20140 citations
Semantic Scholar
Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation
K. Almholt, A. Juncker-Jensen, Ole Didrik Laerum, M. Johnsen +2 more
2012Clinical and Experimental Metastasis0 citations
Semantic Scholar
Abstract 4401: Antibody-mediated targeting of the uPA proteolytic activity neutralizes uPA functionsin vivo
I. Lund, A. Jögi, Birgitte Rønø, M. Rasch +6 more
20100 citations
Semantic Scholar
24 Specific targeting of uPA activity with a monoclonal antibody neutralizeS uPA-dependent effects in vivo
I. Lund, A. Jögi, Birgitte Rønø, M. Rasch +6 more
20080 citations
Semantic Scholar
754 Role of plasminogen activation system
K. Danø, L. R. Lund, K. Almholt, M. Johnsen +3 more
20030 citations
Semantic Scholar
A method of screening substances for detecting intracellular translocation.
O. Thastrup, Sara Petersen Bjoern, S. Tullin, K. Almholt +1 more
19980 citations
Semantic Scholar
A method for screening substances for their effect on intracellular translocation.
K. Almholt, P. Arkhammer, Sara Petersen Bjoern, K. Scudder +3 more
19980 citations
Semantic Scholar
A method for screening of substances with respect to their effect on cAMP levels based on intracellular translocation of PKA
K. Almholt, P. Arkhammar, Sara Petersen Bjoern, K. Scudder +3 more
19980 citations
Semantic Scholar
A method for screening substances which have an effect on intracellular translocation
O. Thastrup, Sara Petersen Bjoern, S. Tullin, K. Almholt +3 more
19980 citations
Semantic Scholar

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L. R. Lund×16
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M. Johnsen×10
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K. Danø — researcher profile on SciRah

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