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M. Kusuhara · SciRah

Researcher profile · Semantic Scholar

M. Kusuhara

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M. Kusuhara — researcher profile on SciRah

h-index: 36
Works: 197
Citations: 4,425

Most-cited papers

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors
K. Ohshima, K. Hatakeyama, T. Nagashima, Yuko Watanabe +14 more
2017Scientific Reports129 citations Open access
Semantic Scholar
Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients
T. Nagashima, Ken Yamaguchi, K. Urakami, Y. Shimoda +31 more
2019Cancer Science83 citations Open access
Semantic Scholar
Implementation of individualized medicine for cancer patients by multiomics-based analyses—the Project HOPE—.
Ken Yamaguchi, K. Urakami, K. Ohshima, T. Mochizuki +6 more
2014Biomedical research58 citations Open access
Semantic Scholar
CYP3A4 Gene Is a Novel Biomarker for Predicting a Poor Prognosis in Hepatocellular Carcinoma.
R. Ashida, Y. Okamura, K. Ohshima, Y. Kakuda +8 more
2017Cancer Genomics & Proteomics55 citations Open access
Semantic Scholar
Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model.
Isako Saga, S. Shibao, Jun Okubo, S. Osuka +8 more
2014Neuro-Oncology52 citations Open access
Semantic Scholar
CD133-positive cancer stem cells from Colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile
Z. Vincent, K. Urakami, Koji Maruyama, Ken Yamaguchi +1 more
2014Genes & cancer49 citations Open access
Semantic Scholar
Metabolomic profiling of gastric cancer tissues identified potential biomarkers for predicting peritoneal recurrence
S. Kaji, T. Irino, M. Kusuhara, R. Makuuchi +12 more
2020Gastric Cancer46 citations Open access
Semantic Scholar
Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing.
K. Hatakeyama, T. Nagashima, K. Urakami, K. Ohshima +10 more
2018Biomedical research43 citations Open access
Semantic Scholar
Next generation sequencing approach for detecting 491 fusion genes from human cancer.
K. Urakami, Y. Shimoda, K. Ohshima, T. Nagashima +11 more
2016Biomedical research38 citations Open access
Semantic Scholar
Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors
K. Ohshima, Keiichi Fujiya, T. Nagashima, Sumiko Ohnami +17 more
2019Cancer Science37 citations Open access
Semantic Scholar
Comprehensive analysis of gene mutation and expression profiles in neuroendocrine carcinomas of the stomach.
R. Makuuchi, M. Terashima, M. Kusuhara, T. Nakajima +5 more
2017Biomedical research36 citations Open access
Semantic Scholar
Organotypic brain explant culture as a drug evaluation system for malignant brain tumors
N. Minami, Y. Maeda, S. Shibao, Y. Arima +8 more
2017Cancer Medicine34 citations Open access
Semantic Scholar
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene
H. Hino, A. Shiomi, M. Kusuhara, H. Kagawa +8 more
2019Cancer Medicine33 citations Open access
Semantic Scholar
Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy
K. Hatakeyama, T. Nagashima, K. Ohshima, Sumiko Ohnami +10 more
2019Cancer Science29 citations Open access
Semantic Scholar
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations
K. Hatakeyama, K. Ohshima, T. Nagashima, S. Ohnami +9 more
2018Scientific Reports29 citations Open access
Semantic Scholar
Metabolome analysis of esophageal cancer tissues using capillary electrophoresis-time-of-flight mass spectrometry.
M. Tokunaga, K. Kami, S. Ozawa, Junya Oguma +5 more
2018International Journal of Oncology29 citations Open access
Semantic Scholar
Integrated next-generation sequencing analysis of whole exome and 409 cancer-related genes.
Y. Shimoda, T. Nagashima, K. Urakami, Tomoe Tanabe +9 more
2016Biomedical research28 citations Open access
Semantic Scholar
Identification of metabolic signatures associated with erlotinib resistance of non-small cell lung cancer cells.
M. Serizawa, M. Kusuhara, Vincent Zangiacomi, K. Urakami +5 more
2014Anticancer Research27 citations
Semantic Scholar
Optimizing an ion semiconductor sequencing data analysis method to identify somatic mutations in the genomes of cancer cells in clinical tissue samples.
T. Nagashima, Y. Shimoda, Tomoe Tanabe, Akane Naruoka +9 more
2016Biomedical research26 citations Open access
Semantic Scholar
CD44 variant 9 expression as a predictor for gastric cancer recurrence: immunohistochemical and metabolomic analysis of surgically resected tissues.
Y. Yamakawa, M. Kusuhara, M. Terashima, Y. Kinugasa +6 more
2017Biomedical research25 citations Open access
Semantic Scholar
Disclosure of secondary findings in exome sequencing of 2480 Japanese cancer patients
Y. Horiuchi, H. Matsubayashi, Kiyozumi Yoshimi, S. Nishimura +9 more
2020Human Genetics22 citations
Semantic Scholar
Associations Between Loss of ARID1A Expression and Clinicopathologic and Genetic Variables in T1 Early Colorectal Cancer.
Yoshihiro Kishida, Takuma Oishi, T. Sugino, A. Shiomi +5 more
2019American Journal of Clinical Pathology22 citations
Semantic Scholar
Classification of tumor microenvironment immune types based on immune response-associated gene expression.
Ryota Kondou, A. Iizuka, C. Nonomura, H. Miyata +7 more
2018International Journal of Oncology19 citations Open access
Semantic Scholar
Assessment of associations between clinical and immune microenvironmental factors and tumor mutation burden in resected nonsmall cell lung cancer by applying machine learning to whole‐slide images
A. Ono, Y. Terada, T. Kawata, M. Serizawa +16 more
2020Cancer Medicine18 citations Open access
Semantic Scholar
The down-regulation of the CYP2C19 gene is associated with aggressive tumor potential and the poorer recurrence-free survival of hepatocellular carcinoma
R. Ashida, Y. Okamura, K. Ohshima, Y. Kakuda +8 more
2018OncoTarget18 citations Open access
Semantic Scholar
Plasma epidermal growth factor receptor mutation testing with a chip-based digital PCR system in patients with advanced non-small cell lung cancer.
N. Kasahara, H. Kenmotsu, M. Serizawa, R. Umehara +15 more
2017Lung Cancer18 citations
Semantic Scholar
Effect of preoperative chemoradiotherapy on the immunological status of rectal cancer patients
K. Yasui, Ryota Kondou, A. Iizuka, H. Miyata +17 more
2020Journal of Radiation Research17 citations Open access
Semantic Scholar
A Fragrant Environment Containing α-Pinene Suppresses Tumor Growth in Mice by Modulating the Hypothalamus/Sympathetic Nerve/Leptin Axis and Immune System
M. Kusuhara, Koji Maruyama, H. Ishii, Yoko Masuda +3 more
2019Integrative Cancer Therapies17 citations Open access
Semantic Scholar
Effect of STAT3 inhibition on the metabolic switch in a highly STAT3-activated lymphoma cell line.
Yasuto Akiyama, A. Iizuka, A. Kume, Masaru Komiyama +6 more
2015Cancer Genomics & Proteomics16 citations
Semantic Scholar
Germline mismatch repair gene variants analyzed by universal sequencing in Japanese cancer patients
Kiyozumi Yoshimi, H. Matsubayashi, Y. Horiuchi, Satomi Higashigawa +8 more
2019Cancer Medicine15 citations Open access
Semantic Scholar
Identification of a neoantigen epitope in a melanoma patient with good response to anti-PD-1 antibody therapy.
C. Nonomura, M. Otsuka, Ryota Kondou, A. Iizuka +16 more
2019Immunology Letters14 citations Open access
Semantic Scholar
Molecular profile of a pleomorphic adenoma of the hard palate
Y. Iida, M. Serizawa, T. Mukaigawa, T. Kamijo +5 more
2020Medicine13 citations Open access
Semantic Scholar
Immune response-associated gene analysis of 1,000 cancer patients using whole-exome sequencing and gene expression profiling-Project HOPE.
Yasuto Akiyama, Ryota Kondou, A. Iizuka, K. Ohshima +9 more
2016Biomedical research13 citations Open access
Semantic Scholar
Genetic alterations of driver genes as independent prognostic factors for disease-free survival in patients with resected non-small cell lung cancer.
A. Ono, M. Isaka, M. Serizawa, K. Omae +14 more
2019Lung Cancer12 citations Open access
Semantic Scholar
Sutureless microvascular anastomosis assisted by an expandable shape-memory alloy stent
Noriko Saegusa, S. Sarukawa, Kunihiro Ohta, Kensuke Takamatsu +7 more
2017PLoS ONE12 citations Open access
Semantic Scholar
Pancreatic adenocarcinoma with a germline PTEN p.Arg234Gln mutation
S. Uemura, H. Matsubayashi, Kiyozumi Yoshimi, K. Uesaka +6 more
2018Familial Cancer10 citations
Semantic Scholar
Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases.
A. Shiomi, M. Kusuhara, T. Sugino, T. Sugiura +6 more
2021Oncology Letters9 citations Open access
Semantic Scholar
Crizotinib-induced simultaneous multiple cardiac toxicities
T. Oyakawa, N. Muraoka, Kei Iida, M. Kusuhara +3 more
2018Investigational new drugs9 citations
Semantic Scholar
Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors
S. Ohnami, K. Ohshima, T. Nagashima, K. Urakami +9 more
2017Molecular and Cellular Biochemistry8 citations Open access
Semantic Scholar
Use of direct oral anti-coagulants for the treatment of venous thromboembolism in patients with advanced cancer: a prospective observational study
T. Oyakawa, N. Muraoka, Kei Iida, M. Kusuhara +1 more
2019International Journal of Clinical Oncology7 citations
Semantic Scholar
Multi-omics Profiling of Patients with Melanoma Treated with Nivolumab in Project HOPE.
S. Yoshikawa, Y. Kiyohara, M. Otsuka, Ryota Kondou +11 more
2017Anticancer Research7 citations Open access
Semantic Scholar
Unstable B7-H4 cell surface expression and T-cell redirection as a means of cancer therapy.
A. Iizuka, Ryota Kondou, C. Nonomura, T. Ashizawa +6 more
2016Oncology Report7 citations Open access
Semantic Scholar
Volatile Components of the Kuromoji Essential Oil (Lindera umbellata Thunb.) and the Utilization for Touch Care Treatment.
K. Sakurai, Eiko Tamai, Yoko Masuda, K. Urakami +1 more
2021Journal of Oleo Science6 citations Open access
Semantic Scholar
BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer
S. Ohnami, K. Maruyama, Kai Chen, Y. Takahashi +15 more
2021Molecular and Cellular Biochemistry6 citations Open access
Semantic Scholar
Metabolic Profiling of Human Gastric Cancer Cells Treated With Salazosulfapyridine
K. Takizawa, Koji Muramatsu, K. Maruyama, K. Urakami +5 more
2020Technology in Cancer Research and Treatment6 citations Open access
Semantic Scholar
Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases: a retrospective study
A. Shiomi, M. Kusuhara, T. Sugino, T. Sugiura +5 more
20206 citations Open access
Semantic Scholar
Characteristics of cellular composition in malignant pericardial effusion and its association with the clinical course of carcinomatous pericarditis
T. Oyakawa, N. Muraoka, Kei Iida, M. Kusuhara +2 more
2018Japanese Journal of Clinical Oncology6 citations
Semantic Scholar
Metabolic profiling of gemcitabine- and paclitaxel-treated immortalized human pancreatic cell lines with K-RASG12D.
A. Todaka, R. Umehara, K. Sasaki, M. Serizawa +4 more
2017Biomedical research6 citations Open access
Semantic Scholar
Prevalence of low-penetrant germline TP53 D49H mutation in Japanese cancer patients.
Ken Yamaguchi, K. Urakami, T. Nagashima, Y. Shimoda +29 more
2016Biomedical research6 citations Open access
Semantic Scholar
Chemotherapy-induced cardiomyopathy caused by Pemetrexed
T. Oyakawa, Kei Iida, M. Kusuhara, H. Kenmotsu +1 more
2018Investigational new drugs5 citations
Semantic Scholar

Frequent co-authors

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K. Urakami×38
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K. Urakami — researcher profile on SciRah
Ken Yamaguchi×36
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Ken Yamaguchi — researcher profile on SciRah
K. Ohshima×25
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K. Ohshima — researcher profile on SciRah
T. Nagashima×24
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T. Nagashima — researcher profile on SciRah

×19

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M. Serizawa — researcher profile on SciRah

Yasuto Akiyama×18

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Yasuto Akiyama — researcher profile on SciRah

Sumiko Ohnami×16

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Sumiko Ohnami — researcher profile on SciRah

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T. Sugino — researcher profile on SciRah

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Y. Shimoda — researcher profile on SciRah

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S. Ohnami — researcher profile on SciRah

T. Mochizuki×13

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T. Mochizuki — researcher profile on SciRah

K. Hatakeyama×12

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K. Hatakeyama — researcher profile on SciRah