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K. Kaarniranta · SciRah

Researcher profile · Semantic Scholar

K. Kaarniranta

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K. Kaarniranta — researcher profile on SciRah

h-index: 87
Works: 545
Citations: 38K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
FinnGen provides genetic insights from a well-phenotyped isolated population
M. Kurki, J. Karjalainen, P. Palta, Timo P. Sipilä +164 more
2023Nature3,914 citations Open access
Semantic Scholar
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C. Bellenguez, F. Küçükali, I. Jansen, L. Kleineidam +496 more
2022Nature Genetics1,984 citations Open access
Semantic Scholar
Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin
A. Salminen, K. Kaarniranta, A. Kauppinen
2022Inflammation Research408 citations Open access
Semantic Scholar
Autophagy in age-related macular degeneration
K. Kaarniranta, J. Błasiak, P. Liton, M. Boulton +2 more
2022Autophagy227 citations Open access
Semantic Scholar
A Linkage between Angiogenesis and Inflammation in Neovascular Age-Related Macular Degeneration
Hanna Heloterä, K. Kaarniranta
2022Cells114 citations Open access
Semantic Scholar
Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population
M. Kurki, J. Karjalainen, P. Palta, Timo P. Sipilä +164 more
2023Nature95 citations Open access
Semantic Scholar
Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases
A. Salminen, K. Kaarniranta, A. Kauppinen
2021Inflammation Research93 citations Open access
Semantic Scholar
Interplay between aging and other factors of the pathogenesis of age-related macular degeneration.
J. Błasiak, Piotr Sobczuk, E. Pawłowska, K. Kaarniranta
2022Ageing Research Reviews76 citations Open access
Semantic Scholar
Micro-RNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy.
J. Hyttinen, J. Błasiak, S. Felszeghy, K. Kaarniranta
2021Ageing Research Reviews45 citations Open access
Semantic Scholar
Tissue fibroblasts are versatile immune regulators: an evaluation of their impact on the aging process.
A. Salminen, K. Kaarniranta, A. Kauppinen
2024Ageing Research Reviews39 citations Open access
Semantic Scholar
Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension: A randomized, double‐masked, vehicle‐controlled study
E. Stefánsson, T. Loftsson, M. Larsen, A. Papp +4 more
2022Acta ophthalmologica36 citations Open access
Semantic Scholar
Therapeutic potential of PGC-1α in age-related macular degeneration (AMD) – the involvement of mitochondrial quality control, autophagy, and antioxidant response
J. Hyttinen, J. Błasiak, P. Tavi, K. Kaarniranta
2021Expert opinion on therapeutic targets28 citations
Semantic Scholar
Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer’s Disease
Sanna Hannonen, S. Andberg, Virve Kärkkäinen, M. Rusanen +10 more
2022Journal of Alzheimer's Disease26 citations Open access
Semantic Scholar
The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
Susanne Csader, Sonja Korhonen, K. Kaarniranta, U. Schwab
2022Nutrients25 citations Open access
Semantic Scholar
A New Generation of Gene Therapies as the Future of Wet AMD Treatment
J. Błasiak, E. Pawłowska, Justyna Ciupińska, M. Derwich +2 more
2024International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD)
J. Hyttinen, J. Błasiak, K. Kaarniranta
2023International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration.
Joel T. Rämö, E. Abner, E. C. van Dijk, Xin Wang +24 more
2023JAMA ophthalmology24 citations Open access
Semantic Scholar
Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
Maeve Boyce, Ying Xin, Olivia Chowdhury, P. Shang +12 more
2022Cells23 citations Open access
Semantic Scholar
Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
J. Błasiak, A. Koskela, E. Pawłowska, M. Liukkonen +9 more
2021International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
J. Błasiak, J. Szczepanska, M. Fila, E. Pawłowska +1 more
2021International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients
Viivi Karema-Jokinen, A. Koskela, M. Hytti, H. Hongisto +7 more
2023Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Activation of cGAS-STING signaling in senescent cells promotes the aging process by remodeling the functions of the immune system
Antero Salminen, K. Kaarniranta, A. Kauppinen
2025Biogerontology (Dordrecht)20 citations Open access
Semantic Scholar
Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata
E. Sliz, J. Tyrmi, N. Rahmioglu, K. Zondervan +323 more
2023Nature Communications18 citations Open access
Semantic Scholar
TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells
S. Ranta-Aho, N. Piippo, E. Korhonen, K. Kaarniranta +2 more
2021International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Ultrasound and Microbubbles for the Treatment of Ocular Diseases: From Preclinical Research towards Clinical Application
C. Rousou, C. Schuurmans, A. Urtti, E. Mastrobattista +4 more
2021Pharmaceutics18 citations Open access
Semantic Scholar
Photoaging: UV radiation-induced cGAS-STING signaling promotes the aging process in skin by remodeling the immune network
A. Salminen, K. Kaarniranta, A. Kauppinen
2025Biogerontology (Dordrecht)17 citations
Semantic Scholar
Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration
J. Błasiak, J. Chojnacki, J. Szczepanska, M. Fila +3 more
2023Nutrients17 citations Open access
Semantic Scholar
Oxidative Stress and Cellular Protein Accumulation Are Present in Keratoconus, Macular Corneal Dystrophy, and Fuchs Endothelial Corneal Dystrophy
Linda Vottonen, A. Koskela, S. Felszeghy, Adam Wylęgała +4 more
2023Journal of Clinical Medicine17 citations Open access
Semantic Scholar
Effect of cataract surgery on wet age‐related macular degeneration activity
Petteri Karesvuo, U. Elbaz, A. Achiron, I. Hecht +2 more
2021Acta ophthalmologica17 citations Open access
Semantic Scholar
Visual impairment due to age‐related macular degeneration during 40 years in Finland and the impact of novel therapies
Petri K. M. Purola, K. Kaarniranta, M. Ojamo, M. Gissler +1 more
2022Acta ophthalmologica16 citations Open access
Semantic Scholar
Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration
J. Błasiak, J. Hyttinen, J. Szczepanska, E. Pawłowska +1 more
2021International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Hypoxia/ischemia impairs CD33 (Siglec-3)/TREM2 signaling: Potential role in Alzheimer's pathogenesis.
A. Salminen, K. Kaarniranta, A. Kauppinen
2021Neurochemistry International15 citations Open access
Semantic Scholar
Secretory autophagy: a turn key for understanding AMD pathology and developing new therapeutic targets?
J. Błasiak, K. Kaarniranta
2022Expert opinion on therapeutic targets14 citations
Semantic Scholar
Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
M. Amirkavei, Flavia Plastino, A. Kvanta, K. Kaarniranta +2 more
2022Cells14 citations Open access
Semantic Scholar
Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α -/- Mouse Model Evoke Complement Component C5a Independent of C3
Iswariyaraja Sridevi Gurubaran, Hanna Heloterä, Stephen Marry, A. Koskela +7 more
2021Biology13 citations Open access
Semantic Scholar
Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals
Perttu J Liuska, Joel T. Rämö, S. Lemmelä, K. Kaarniranta +6 more
2023Investigative Ophthalmology and Visual Science12 citations Open access
Semantic Scholar
Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study
V. D. de Mello, T. Selander, J. Lindström, J. Tuomilehto +2 more
2021Nutrients12 citations Open access
Semantic Scholar
The role of secretory autophagy and exosomes in the accumulation of drusen during the development of age-related macular degeneration (AMD).
J. Hyttinen, M. Niittykoski, K. Kaarniranta
2025Ageing Research Reviews11 citations Open access
Semantic Scholar
NTHL1 is a recessive cancer susceptibility gene
Anna K. Nurmi, L. Pelttari, J. Kiiski, Sofia Khan +333 more
2023Scientific Reports11 citations Open access
Semantic Scholar
PGC‐1α regulates the interplay between oxidative stress, senescence and autophagy in the ageing retina important in age‐related macular degeneration
Iswariyaraja Sridevi Gurubaran, Cezary Watała, Joanna Kostanek, J. Szczepanska +3 more
2024Journal of Cellular and Molecular Medicine10 citations Open access
Semantic Scholar
Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration
M. Hytti, E. Korhonen, H. Hongisto, K. Kaarniranta +2 more
2021International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells
A. Koskela, F. Manai, Filippo Basagni, M. Liukkonen +6 more
2022Antioxidants9 citations Open access
Semantic Scholar
Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells
Niina Bhattarai, E. Korhonen, Y. Mysore, K. Kaarniranta +1 more
2021Cells8 citations Open access
Semantic Scholar
A FinnGen pilot clinical recall study for Alzheimer’s disease
V. Julkunen, C. Schwarz, Juho Kalapudas, M. Hallikainen +325 more
2023medRxiv7 citations Open access
Semantic Scholar
Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired
Juha-Matti Lehtola, Virve Kärkkäinen, S. Andberg, Sanna Hannonen +10 more
2022Alzheimer Disease and Associated Disorders7 citations Open access
Semantic Scholar
Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population.
Perttu J Liuska, S. Lemmelä, A. Havulinna, K. Kaarniranta +6 more
2021JAMA ophthalmology7 citations Open access
Semantic Scholar
Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells
Iswariyaraja Sridevi Gurubaran, M. Hytti, K. Kaarniranta, A. Kauppinen
2022Antioxidants6 citations Open access
Semantic Scholar
Cis-urocanic acid improves cell viability and suppresses inflammasome activation in human retinal pigment epithelial cells.
E. Korhonen, N. Piippo, M. Hytti, K. Kaarniranta +1 more
2023Biochemical Pharmacology5 citations Open access
Semantic Scholar
Comparison of barrier properties of outer blood-retinal barrier models - human stem cell-based models as a novel tool for ocular drug discovery.
Laura Hellinen, H. Hongisto, Eva Ramsay, K. Kaarniranta +3 more
2023European journal of pharmaceutics and biopharmaceutics5 citations Open access
Semantic Scholar

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A. Kauppinen — researcher profile on SciRah
J. Błasiak×11
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