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R. Topless · SciRah

Researcher profile · Semantic Scholar

R. Topless

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R. Topless — researcher profile on SciRah

h-index: 27
Works: 73
Citations: 2,438

Most-cited papers

Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts
T. J. Major, R. Topless, N. Dalbeth, T. Merriman
2018British medical journal210 citations Open access
Semantic Scholar
Twenty-eight loci that influence serum urate levels: analysis of association with gout
A. Phipps-Green, M. Merriman, R. Topless, S. Altaf +8 more
2014Annals of the Rheumatic Diseases144 citations
Semantic Scholar
Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case-control sample sets.
Jade E. Hollis-Moffatt, Xin Xu, N. Dalbeth, M. Merriman +8 more
2009Arthritis & Rheumatism138 citations
Semantic Scholar
A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets.
A. Phipps-Green, Jade E. Hollis-Moffatt, N. Dalbeth, M. Merriman +7 more
2010Human Molecular Genetics133 citations Open access
Semantic Scholar
No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study
Daniel M. Jordan, Hyon K. Choi, M. Verbanck, R. Topless +4 more
2019PLoS Medicine127 citations Open access
Semantic Scholar
Sugar-sweetened beverage consumption: a risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout
C. Batt, A. Phipps-Green, M. Black, M. Cadzow +9 more
2013Annals of the Rheumatic Diseases111 citations Open access
Semantic Scholar
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm.
Gregory T. Jones, M. Bown, S. Gretarsdottir, Siôn Romaine +34 more
2013Human Molecular Genetics110 citations Open access
Semantic Scholar
Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease
R. Roberts, R. Topless, A. Phipps-Green, R. Gearry +2 more
2010Genes and Immunity104 citations Open access
Semantic Scholar
A genome-wide association analysis reveals new pathogenic pathways in gout
T. J. Major, R. Takei, H. Matsuo, M. Leask +95 more
2024Nature Genetics91 citations Open access
Semantic Scholar
ABCG2 loss-of-function polymorphism predicts poor response to allopurinol in patients with gout
R. Roberts, M. Wallace, A. Phipps-Green, R. Topless +5 more
2016The Pharmacogenomics Journal87 citations
Semantic Scholar
The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samples.
L. Rodríguez-Rodríguez, W. Taib, R. Topless, S. Steer +19 more
2011Arthritis & Rheumatism81 citations Open access
Semantic Scholar
Discordant association of the CREBRF rs373863828 A-allele with increased body mass index and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa New Zealand
M. Krishnan, T. J. Major, R. Topless, O. Dewes +22 more
2018Diabetologia73 citations Open access
Semantic Scholar
Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout
C. McKinney, L. Stamp, N. Dalbeth, R. Topless +12 more
2015Arthritis Research & Therapy67 citations Open access
Semantic Scholar
Mendelian Randomization Analysis to Examine for a Causal Effect of Urate on Bone Mineral Density
N. Dalbeth, R. Topless, Tanya J. Flynn, M. Cadzow +2 more
2015Journal of Bone and Mineral Research56 citations Open access
Semantic Scholar
Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects
Tanya J. Flynn, A. Phipps-Green, Jade E. Hollis-Moffatt, M. Merriman +6 more
2013Arthritis Research & Therapy54 citations Open access
Semantic Scholar
Population specific resequencing associates the ATP Binding Cassette Subfamily C Member 4 (ABCC4) gene with gout in New Zealand Māori and Pacific men
C. Tanner, J. Boocock, E. Stahl, Amanda Dobbyn +10 more
2017Arthritis & Rheumatology52 citations Open access
Semantic Scholar
Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption
Humaira Rasheed, A. Phipps-Green, R. Topless, Jade E. Hollis-Moffatt +7 more
2013Arthritis Research & Therapy51 citations Open access
Semantic Scholar
Gout, Rheumatoid Arthritis, and the Risk of Death Related to Coronavirus Disease 2019: An Analysis of the UK Biobank
R. Topless, A. Phipps-Green, M. Leask, N. Dalbeth +3 more
2021ACR Open Rheumatology48 citations Open access
Semantic Scholar
Association between ABCG2 rs2231142 and poor response to allopurinol: replication and meta-analysis
M. Wallace, R. Roberts, Payal Nanavati, J. Miner +4 more
2018Rheumatology48 citations Open access
Semantic Scholar
Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout
R. Wrigley, A. Phipps-Green, R. Topless, T. J. Major +11 more
2020Arthritis Research & Therapy47 citations Open access
Semantic Scholar
Testing the Validity of Taxonic Schizotypy Using Genetic and Environmental Risk Variables
Sarah E. Morton, Kirstie J. M. O'Hare, Jaimee L. K. Maha, Max P. Nicolson +4 more
2016Schizophrenia bulletin43 citations Open access
Semantic Scholar
The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets
Humaira Rasheed, C. McKinney, L. Stamp, N. Dalbeth +17 more
2016PLoS ONE42 citations Open access
Semantic Scholar
Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance
Jade E. Hollis-Moffatt, M. Chen-Xu, R. Topless, N. Dalbeth +10 more
2010Arthritis Research & Therapy42 citations Open access
Semantic Scholar
Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study
R. Topless, A. Gaffo, L. Stamp, P. Robinson +2 more
2022The Lancet Rheumatology33 citations Open access
Semantic Scholar
Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares
Tanya J. Flynn, M. Cadzow, N. Dalbeth, Peter B. B. Jones +6 more
2015BMC Musculoskeletal Disorders33 citations Open access
Semantic Scholar
The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: diet has a weak causal effect
R. Topless, T. J. Major, J. Florez, J. Hirschhorn +7 more
2021Arthritis Research & Therapy30 citations Open access
Semantic Scholar
Interactions between serum urate-associated genetic variants and sex on gout risk: analysis of the UK Biobank
R. Narang, R. Topless, M. Cadzow, G. Gamble +3 more
2019Arthritis Research & Therapy27 citations Open access
Semantic Scholar
Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout
N. Sumpter, R. Takei, M. Cadzow, R. Topless +35 more
2022Arthritis & Rheumatology25 citations Open access
Semantic Scholar
Factors associated with orthodontic pain
Wei Lin, M. Farella, J. Antoun, R. Topless +2 more
2021Journal of Oral Rehabilitation24 citations Open access
Semantic Scholar
Assessing the Relationship Between Serum Urate and Urolithiasis Using Mendelian Randomization: An Analysis of the UK Biobank.
R. Narang, G. Gamble, R. Topless, M. Cadzow +3 more
2021American Journal of Kidney Diseases23 citations
Semantic Scholar
Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR
M. Leask, Amy Dowdle, Hamish A. Salvesen, R. Topless +8 more
2019Frontiers in Genetics23 citations Open access
Semantic Scholar
Mediation analysis to understand genetic relationships between habitual coffee intake and gout
J. Hutton, Tahzeeb Fatima, T. J. Major, R. Topless +3 more
2018Arthritis Research & Therapy21 citations Open access
Semantic Scholar
Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.
Humaira Rasheed, A. Phipps-Green, R. Topless, Malcolm D. Smith +18 more
2016Rheumatology20 citations Open access
Semantic Scholar
Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women
R. Topless, Tanya J. Flynn, M. Cadzow, L. Stamp +3 more
2015Frontiers in Genetics20 citations Open access
Semantic Scholar
Mid-pass whole genome sequencing enables biomedical genetic studies of diverse populations
A. Emde, A. Phipps-Green, M. Cadzow, C. Gallagher +13 more
2021BMC Genomics16 citations Open access
Semantic Scholar
Replication of association of the interleukin 23 receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets
M. Chen-Xu, R. Topless, C. McKinney, M. Merriman +24 more
2011Annals of the Rheumatic Diseases16 citations Open access
Semantic Scholar
A genome-wide association analysis of 2,622,830 individuals reveals new pathogenic pathways in gout.
T. J. Major, R. Takei, H. Matsuo, M. Leask +39 more
2022medRxiv14 citations Open access
Semantic Scholar
Association study involving polymorphisms in IL-6, IL-1RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of Māori and Pacific ancestry.
P. M. Azevedo, T. Merriman, R. Topless, N. Wilson +2 more
2016Cytokine14 citations
Semantic Scholar
Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout
Tahzeeb Fatima, S. Altaf, A. Phipps-Green, R. Topless +4 more
2015Rheumatology International13 citations Open access
Semantic Scholar
The Oxytocin Receptor Gene (OXTR) Variant rs53576 Is Not Related to Emotional Traits or States in Young Adults
T. Conner, Karma G. McFarlane, Maria Choukri, Benjamin C. Riordan +5 more
2018Frontiers in Psychology12 citations Open access
Semantic Scholar
Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus
A. Ji, A. Shaukat, R. Takei, M. Bixley +10 more
2021Journal of Rheumatology11 citations
Semantic Scholar
No evidence for association of the systemic lupus erythematosus-associated ITGAM variant, R77H, with rheumatoid arthritis in the Caucasian population.
A. Phipps-Green, R. Topless, M. Merriman, N. Dalbeth +8 more
2009Rheumatology11 citations
Semantic Scholar
Gout, rheumatoid arthritis and the risk of death from COVID-19: an analysis of the UK Biobank
R. Topless, A. Phipps-Green, M. Leask, N. Dalbeth +3 more
2020medRxiv9 citations Open access
Semantic Scholar
Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity
,-Chu Min, M. Leask, R. Topless, Gregory D. Gamble +4 more
2024Arthritis Research & Therapy8 citations Open access
Semantic Scholar
Change in serum urate level with urate-lowering therapy initiation associates in the immediate term with patient-reported outcomes in people with gout.
R. Topless, S. Noorbaloochi, T. Merriman, Jasvinder A. Singh
2022Seminars in Arthritis & Rheumatism8 citations
Semantic Scholar
Do Serum Urate–associated Genetic Variants Influence Gout Risk in People Taking Diuretics? Analysis of the UK Biobank
R. Narang, G. Gamble, A. Phipps-Green, R. Topless +4 more
2020Journal of Rheumatology8 citations
Semantic Scholar
Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia
Rebecca Debono, R. Topless, D. Markie, M. Black +1 more
2012Genes, Brain and Behavior8 citations Open access
Semantic Scholar
Folic acid and methotrexate use and their association with COVID-19 diagnosis and mortality: a case–control analysis from the UK Biobank
R. Topless, Ralph Green, S. Morgan, P. Robinson +2 more
2022BMJ Open7 citations Open access
Semantic Scholar
A Polynesian-specific copy number variant encompassing the MHC Class I Polypeptide-related Sequence A (MICA) gene associates with gout.
Ke Wang, M. Cadzow, M. Bixley, M. Leask +15 more
2022Human Molecular Genetics6 citations Open access
Semantic Scholar
Genetic Polymorphisms on OPRM1, DRD2, DRD4, and COMT in Young Adults: Lack of Association With Alcohol Consumption
Patrick Chung, W. Logge, Benjamin C. Riordan, P. Haber +6 more
2020Frontiers in Psychiatry6 citations Open access
Semantic Scholar

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